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Yahoo
19 hours ago
- Entertainment
- Yahoo
Jonathan Anderson's Dior Man Is a Delight
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." There's a new (new, new) look at Dior. After weeks of teasing glimpses, Jonathan Anderson has finally started to unveil his vision for the nearly 80-year-old fashion house. At Les Invalides in Paris, Anderson showed his debut collection for Dior men's and presented an entirely fresh vernacular for the global brand—one that delicately balanced the historical with the present while presenting lots of propositions for the future. The livestream began with videos of brand ambassadors traveling to the show. Lakeith Stanfield and Josh O'Connor chitchatted in the back of the cab, while Robert Pattinson leisurely strolled into an elevator. All of these guys were decked out in Anderson's new Dior, or perhaps it was less decked out and more dressed. Impossibly stylish, the clothes bend the arch between a dapper man and someone who's a bit of a scoundrel. Outside, Anderson collaborator and friend the director Luca Guadagnino was filming some of the recognizable guests who began to arrive, like Sam Nivola and Donatella Versace. Rihanna and A$AP Rocky were there. Sabrina Carpenter pulled up wearing an Anderson-ized version of Dior's New Look. Inside the venue, a nearly-empty gallery space had been built, punctuated only by light parquet floors and wooden blocks for seats. The walls were sparsely hung with still life paintings by Old Masters like Jean Siméon Chardin, whose work Monsieur Dior was fond of. Other than Versace, several more designers came out to support Anderson, including Pierpaolo Piccioli and Matthieu Blazy, both set to make their own debuts, at Balenciaga and Chanel respectively, this fall. The anticipation for this collection was high, to say the least. Once the first look hit the runway, it was clear just how much the hype had been warranted. Bang out of the gate, a hit: Anderson paired a Donegal tweed bar jacket with ballooning cargo shorts fastened with a pleated, cascading bustle at the back, a design loosely inspired by the mille-feuille dress silhouettes Monsieur Dior showed at the beginning of his career. Everything that followed painted a delightful, whip-smart portrait of the past infused with the present. Riffing off of ideas from his final womenswear collection for Loewe last year, Anderson wrote in the show notes that these pieces were meant to signify 'a reconstruction of formality' and celebrate the 'joy in the art of dressing: a spontaneous, empathetic collusion of then and now, of relics of the past things rediscovered in the archives, classic tropes of class, and pieces that have endured the test of time.' For any other designer, finding resonance with 'then and now' at a storied house might manifest itself as a re-issue. Anderson is one of the most important designers of his generation because he understands how not to do that. He makes things that are recognizable and ripped from history books and turns them into something we've never seen before. For Spring 2026, Anderson did this by crafting precise replicas of embroidered waistcoats and pairing them with white jeans and sneakers. Basic neckties were loose and worn flipped over to reveal Anderson's revamp of the Dior logo—a journey back to its roots when M. Dior, in his exacting way, would only settle for a French-style font. There were classic cravats and rococo-style micro-florals set against athletic socks and fisherman sandals. Anderson's new book totes were carried throughout the show, touting titles like Bonjour Tristesse and In Cold Blood—accessories for a hot dude who reads. The capes and maxi shirt-dresses added touches of Anderson's signature kookiness, abstracting and bending the idea of time even further. These men were dandy and regal, but also a little rough around the edges, the kind that Anderson has made into a bona fide style archetype over the last decade. No one else could, at least in this moment, make eighteenth-century wardrobe staples feel like they belonged with a pair of barrel leg jeans. Anderson imagines completely unimaginable wardrobes for those outside of the fashion sphere, for those who never thought a tie could be worn backwards or a pair of cargos could sashay. The biggest challenge of these gargantuan creative director jobs at luxury houses is being everything to everyone—being a creative director whose clothes, marketing, ambassadors, and accessories appeal to the classic brand loyalists, the high-net worth clients who want a logo splattered all over their bodies, and the kids who are looking for someone to tell them what's coming next. Anderson can imagine something for every luxury customer, and he has the vision to build new sartorial archetypes through instinctive design. He got a standing ovation of course, walking out with a shy swagger, the kind we'd just witnessed reverberate through the clothes he showed on the runway. This is the delight and the dream of Anderson. It was then, it is now, and it will be as he keeps moving ahead at Dior. You Might Also Like 4 Investment-Worthy Skincare Finds From Sephora The 17 Best Retinol Creams Worth Adding to Your Skin Care Routine
Yahoo
a day ago
- Health
- Yahoo
Does Rice-Zempic Do Anything? What Doctors Want You to Know
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links."You're probably aware that quick-fix weight loss hacks generally aren't recommended by healthcare professionals and, if you're concerned about your weight, it's always a good idea to check in with a doctor for guidance. But lately, people on TikTok are claiming rice water, a.k.a. 'rice-zempic,' has helped them lose weight. So, it's fair to wonder what this is about. While medications like Ozempic and Mounjaro have exploded in popularity, they can be pricey and aren't always accessible. That's opened the door for unproven strategies that claim to be as good as these injectables for helping people lose weight. Enter rice water for weight loss. Here's the backstory, plus what doctors and a dietitian really think about it. Meet the experts: Kunal Shah, M.D., is an assistant professor in the division of endocrinology at the Rutgers Robert Wood Johnson Medical Center. Mir Ali, M.D., is a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center; Scott Keatley, R.D., is co-owner of Keatley Medical Nutrition Therapy; Darin Detwiler, author of the book Food Safety: Past, Present, and Predictions and a professor at Northeastern University There are variations on Rice-zempic, but it usually includes a similar recipe that features three ingredients: unwashed rice, warm or hot water, and lime juice. People say that they let the rice steep in water overnight, remove the rice, add the lime juice, and drink the leftover starchy solution. Some note they'll drink it about a half an hour before eating, and then follow their usual diet. There are a few potential risks to keep in mind with rice water, including some food safety concerns. 'Drinking unwashed, uncooked rice water poses clear microbiological and chemical safety risks,' says Darin Detwiler, author of the book Food Safety: Past, Present, and Predictions and a professor at Northeastern University. Raw rice can carry bacterial spores like Bacillus cereus, along with residues from pesticides, herbicides, and arsenic, especially in regions where water or soil is contaminated, Detwiler points out. 'Washing rice before use helps remove surface contaminants,' Detwiler says. Skipping that step increases the likelihood of ingesting residues, especially if the rice isn't organic or clearly labeled as washed or pre-cleaned.' Separately, Mir Ali, M.D., medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center, points out that this drink is likely high in carbohydrates, noting that, in excess, they can be 'counterproductive' to weight loss. And weight regain (if you lose any in the first place) is also a risk, Dr. Ali says. 'This weight loss will be temporary because you're not making permanent, healthy, long-term changes,' he says. 'Once you stop doing this kind of thing, the weight will come back.' Also, if you have an underlying health condition like acid reflux, downing lime juice daily may exacerbate symptoms, Dr. Shah says. Maybe, but it's probably not as significant as people are hoping. 'It is relatively low-calorie—it's just starchy water,' says Dr. Ali. Rice water may cause people to feel full before a meal, leading them to eat less than they normally would, Dr. Ali says. (It's not clear where the lime juice comes in, but it may simply be used to add flavor.) But this hack has 'zero scientific backing,' says Scott Keatley, R.D., co-owner of Keatley Medical Nutrition Therapy. 'While rice water may have some nutritional benefits, such as providing a source of energy from its starch content, there is no evidence to suggest it has any properties that would significantly impact weight loss,' especially in the manner that some weight loss medications do, he says. Rice water can also make you feel bloated, points out Kunal Shah, M.D., an assistant professor in the division of endocrinology at the Rutgers Robert Wood Johnson Medical Center. 'The starch expands in your stomach and can make you feel full—but it's very short-lived,' he says. Also, doctors stress that rice water is not in the same ballpark as medications like Ozempic and Wegovy. 'It's really not metabolically helping you at all,' Dr. Shah says. 'It doesn't in any way mimic Ozempic,' Dr. Ali agrees. 'It has no hormonal effects like Ozempic.' There are some claims that rice water contains resistant starch, a complex carbohydrate that the body can't break down to be digested. (Resistant starch is linked with weight management.) But while resistant starch is usually created when rice is cooked and then cooled, it's not clear if making rice water actually has this effect. Rice itself also contains vitamins and minerals like iron, calcium, magnesium, and zinc, but it's uncertain if those nutrients transfer to rice water. If you want to lose weight and you're not sure where to start, it's a good idea to consult with a healthcare provider first, Dr. Ali says. They can give you an evaluation and provide scientifically-sound advice to help you meet your goals. But drinking rice water really isn't the safest way to lose weight, both from a food safety and overall health perspective. 'I don't want people to misconstrue this as Ozempic—it's not,' Dr. Ali says. You Might Also Like Can Apple Cider Vinegar Lead to Weight Loss? Bobbi Brown Shares Her Top Face-Transforming Makeup Tips for Women Over 50
Yahoo
a day ago
- Health
- Yahoo
Scientists Found a Secret Weapon That May Stop Blindness Before It Starts
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." Here's what you'll learn when you read this story: Age-related macular degeneration (AMD) is the most common cause of blindness in people over the age of 50, and while there are treatments, there are few options to stop the degradation in its tracks once the disease has taken hold. A new study finds that the molecule apolipoprotein M, or ApoM—known for its protective and anti-inflammatory qualities—could help clear away vision-damaging cholesterol deposits as they accumulate in the retina. Not only could an increased dose of ApoM in the bloodstream help ward off AMD, the molecule could be useful in treating certain heart ailments as well. The human eye is a wonder of evolution, but it's also host to a variety of maladies that can make a once clear, crisp, and colorful world a dull and blurry one. One of the most prevalent of these vision-based ailments is age-related macular degeneration (AMD)—when the central part of our retina (the macula) begins to waste away. This begins with changes in the retinal pigmented epithelium, which guard the inside and outside of the retinal, as they begin failing to clear waste away from the eye. AMD is the leading cause of blindness in people over 50, and the disease leads to an overall loss of central vision, which is needed for reading, driving, and recognizing faces (all pretty important stuff). Now, a team of researchers—led by scientists at Washington University (WashU) in St. Louis—has found a handy molecule that could possibly help treat AMD as well as certain ailments in the heart. Known as apolipoprotein M, or ApoM, this molecule is a lipocalin (an extracellular protein capable of transporting hydrophobic molecules) that binds with the bioactive lipid sphingosine-1-phosphate, or S1p. The new study found that when this protein was increased in the bloodstream, it helped clear away the cholesterol-rich deposits in the eye that lead to AMD. The results of the study were published in the journal Nature Communications. 'Current therapies that reduce the chance of further vision loss are limited to only the most advanced stages of macular degeneration and do not reverse the disease,' Rajendra S. Apte, the senior author of the study from WashU, said in a press statement. 'Our findings suggest that developing treatments that increase ApoM levels could treat or even prevent the disease and therefore preserve people's vision as they age.' These cholesterol deposits are only the beginning of a patient's problems when experiencing AMD. Someone might not experience any vision loss in the early stages of this disease, but the deposits eventually increase inflammation and eventually lead to 'dry' macular degeneration caused by geographic atrophy—a kind of neurodegeneration that's also found in Alzheimer's patients. While treatable, this advanced stage of AMD is not reversible. However, new treatment using ApoM—which, in recent years, has been shown to be a protective molecule with anti-inflammatory attributes—could potentially stop AMD before it develops past the point of no return. When tested in mice, the rodents showed evidence of improved retinal health, including both better performance from light-sensing cells in the retina and reduced cholesterol build-up. Of course, there's another area of the body particularly sensitive to cholesterol—the heart. Amazingly, the researchers also found that ApoM could also play a pivotal role in treating certain heart diseases. 'One of the exciting things about this collaboration is realizing the links between retinal pigment epithelial cells and heart muscle cells, which are both vulnerable to low ApoM,' Ali Javeheri, a co-author of the study from WashU, said in a press statement. 'It is possible that the interaction between ApoM and S1P is regulating cholesterol metabolism in both cell types.' The eye is undoubtedly one of the most impressive organs we have, and a new era of vision medicine aims to keep it that way, even as we age through the years. You Might Also Like The Do's and Don'ts of Using Painter's Tape The Best Portable BBQ Grills for Cooking Anywhere Can a Smart Watch Prolong Your Life?
Yahoo
2 days ago
- Entertainment
- Yahoo
Lauren Sánchez's Pre-Wedding Look Was Impossibly Cinched
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." The wedding fashion rollout continues in Italy. On Friday, Amazon founder Jeff Bezos and American journalist Lauren Sánchez will tie the knot in Venice, where the stars have already been showing up in full force to witness the nuptials, including the Kardashian-Jenner clan, Oprah, Orlando Bloom, Tom Brady, and more. Now, the bride-to-be has made her grand appearance for her welcome party, and in Schiaparelli couture, no less. The former Extra correspondent was seen stepping onto a boat with her fiancé, as the two prepared to dine with their wedding guests at the Madonna dell'Orto church. For the soirée, Sánchez chose an eye-popping off-the-shoulder dress pulled from the Spring 2025 Schiaparelli couture collection, designed by Daniel Roseberry and titled 'Icarus.' Her dress featured a jutting, folded-over neckline that, like the skintight midi skirt, was embroidered with designs of swirling vines, florals, and eyes—all in hues of iridescent blue, green, and gold that were set against a champagne fabric. However, it was the contrasting waist that stole the show. The ribbed midsection featured a tightly-wrapped swirl of gold material that cinched Sánchez's body like a spool of thread. In fact, the corset-style swathe was so cinched that the bride needed her husband-to-be to hold her hand as she stepped onto their water taxi. To complete her look, The Fly Who Flew to Space author slipped into a pair of matching metallic gold pumps. For glam, she pulled her hair back into a high ponytail with a few strands hanging like curtains in front of her face—a look that showed off her large diamond earrings. Based on the lavishness of the nuptials, this surely won't be the last designer look we see on Sánchez. You Might Also Like 4 Investment-Worthy Skincare Finds From Sephora The 17 Best Retinol Creams Worth Adding to Your Skin Care Routine
Yahoo
2 days ago
- Health
- Yahoo
The Pharoah's Curse Once Killed Archaeologists. Now It Could Help Fight Cancer.
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." The toxic fungus Aspergillus flavus—known as the 'Pharaoh's Curse' due to its role in the deaths of archaeologists who opened the Tomb of Tutankhamun in the 1920s—could have cancer-fighting abilities. A new study developed ribosomally synthesized and post-translationally modified peptides (RiPPs), which produced novel structures of interlocking rings called 'asperigimycins.' When combined with a lipid, these asperigimycins disrupted cell division in leukemia cancer cells, and were as effective as FDA-approved therapies that have treated the disease for decades. Fungi hold a prominent place in the history of medicine. Discovered in 1928, the world's first antibiotic—penicillin–was derived from a simple mold, and since then, fungi have made their way into the ingredient lists of all kinds of immunosuppressants and cholesterol-lowering drugs. Some fungi with psychoactive properties are even being introduced in states across the U.S. as therapeutic tools. However, not all fungi are medicinally helpful, and one of the more cursed members of the kingdom Fungi is Aspergillus flavus. A true microbial villain, this toxic fungus can produce aflatoxins, which can cause a variety of health issues and even death. The fungus garnered the cryptic nickname 'Pharaoh's Curse' due to it being linked to the deaths of several archeologists who opened ancient tombs around the world, including the famous discovery of the Tomb of Tutankhamun in the 1920s. However, a new study published in the journal Nature Chemical Biology analyzes a wholly different aspect of this fungal villain—it's cancer-fighting properties. The group of scientists led by researchers at the University of Pennsylvania (Penn) modified A. flavus and found molecules that formed a unique structure of interlocking rings, which they named 'asperigimycins.' When mixed with human leukemia cancer cells, these molecules—described as a class of ribosomally synthesized and post-translationally modified peptides, or RiPPs—were effective at knocking them out of commission. When the researchers added lipids (fatty molecules) to the mixture, the 'Pharaoh's Curse' transformed into a microbial blessing that worked as effectively as the FDA-approved drugs that've treated leukemia for decades. 'Fungi gave us penicillin,' Sherry Gao, senior author of the paper from Penn, said in a press statement. 'These results show that many more medicines derived from natural products remain to be found.' To better understand the properties of these RiPPs, the scientists selectively turned genes in the leukemia cells on and off. In doing so, they found that the SLC46A3 gene was crucial for the asperigimycins to enter the cancerous cells in enough numbers to be effective. The added lipid impacts how that gene transported chemicals into the cells, increasing their potency. However, the research team confirmed that these RiPPs were only useful against leukemia cells, and appeared to have no impact on breast, liver, or lung cancer cells. So, its usefulness is specific. Once in the cells, the asperigimycins prevent cell division, which is the process by which cancer spreads. 'Cancer cells divide uncontrollably,' Gao said in a press statement. 'These compounds block the formation of microtubules, which are essential for cell division." The hope is to soon move testing of these compounds into animal models, and then continue onward to human trials in an effort to develop a new method of treating deadly cancers. 'Nature has given us this incredible pharmacy,' Gao said in a press statement. 'It's up to us to uncover its secrets. As engineers, we're excited to keep exploring, learning from nature and using that knowledge to design better solutions.' What once was a pharaoh's curse might one day turn out to be an oncologist's blessing. You Might Also Like The Do's and Don'ts of Using Painter's Tape The Best Portable BBQ Grills for Cooking Anywhere Can a Smart Watch Prolong Your Life?
