Latest news with #ISH
RTÉ News
20-07-2025
- Sport
- RTÉ News
Seamus Hughes Kennedy and Darragh Kenny finish well at European Show Jumping Championships
Seamus Hughes Kennedy and Darragh Kenny completed a fine week for the Irish at the 38th Longines FEI European Show Jumping Championships to finish fifth and seventh respectively in the individual standings. Both elicited foot-perfect rounds from ESI Rocky (ISH) and Eddy Blue to record outstanding finishes from a field of 89 that started out on Wednesday. Kilkenny youngster Hughes Kennedy and the ten-year-old bred by his uncles Andrew and Niall, did not have a jumping error in five rounds in Spain and while one time fault left the 22-year-old frustrated, in the end, it only cost him fourth rather than a medal. He had started the day in seventh, so his tally of one fault from his fourth and fifth rounds brought him up two places with a paltry 3.16 faults. Kenny recorded a brilliant double clear on Carol Sollak's Eddy Blue, who was very unfortunate to knock his only fence all week, when having a stumble in Wednesday's speed and handiness class won by Daniel Coyle and Legacy. Victory went to Richard Vogel (GER) with United Touch S on a staggering 0.01 faults, accumulated by virtue of finishing three-hundredths of a second off Coyle and Legacy. Britain's Scott Brash took silver with Hello Folie (1.08) while Gilles Thomas, a star of Belgium's gold medal winning performance in the team event, completed the podium with Ermitage Kalone (1.37). The Irish pair were central cogs as Michael Blake's unit finished fourth in the team event, ahead of 18 nations, and they continued to shine in the white heat of elite competition. Making his senior championship debut, Hughes Kennedy was over the moon, although there was a hint of what might have been, having finished so close to medalling in both the team and medal competitions. "I'm delighted with the result in the finish," said Hughes Kennedy. "Pity not to get a medal in the end after doing the full week without knocking a jump but the plan the first day, everything came off exactly the way we wanted and in the end that wasn't quite enough to win a medal. We were expecting a few more people to have a mistake here or there. "I was delighted with the way the horse jumped, delighted with the opportunity to be able to come out here that Michael Blake has given us to come and be on the team. "It was unfortunate to just miss out on a medal for the teams and to also just miss out on a medal in the individual result as well but we couldn't ask for anymore. The horse jumped brilliant, it was a great championship, especially our first senior championship. "It was a long week and everything went according to plan and to be fifth in the end was a great result and I look forward to the future with such a special horse."
RTÉ News
11-07-2025
- Sport
- RTÉ News
Ireland claim Under-18 European show jumping crown
The Irish show jumping team are the new Under-18 European champions, following an outstanding performance at the FEI European Championships for Young Riders (U21), Juniors (U18) and Children (U14) at Riesenbeck in Germany. The Irish team of Sligo's Paddy Reape (Mr Rocky Blue (ISH), Tipperary's Tabitha Kyle (BP Goodfellas (ISH), Tipperary's Alice Wachman (Killarney) and Kilkenny's Emily Moloney (Temple Alice (ISH), along with reserve rider Jack Kent, moved into the gold medal position following a flawless display on Wednesday. Ireland, managed by Denis Flannelly, produced another foot-perfect display in Thursday's medal decider, with three clear rounds keeping them on a score of 6.99 to secure the European team gold medal. The Netherlands claimed silver on 12.79 while Belgium grabbed the bronze medal on 20.60. Moloney heads into Saturday's Junior individual final in the silver medal position, less than two penalties off the gold medal spot. Tabitha Kyle is n eighth position, while Alice Wachman is in 10th as just over one fence separates the top 10 riders in a very tight leaderboard. Meanwhile, the Irish U21 team have also moved into the gold medal spot in their competition. Managed by Michael Blake, the Irish quartet of Tom Wachman (Obora's Laura), Coen Williams (Floris R Z), Tim Brennan (Diadema della Caccia) and Niamh McEvoy (BP Rocket Man (ISH), are on a score of 4.61. Belgium are in silver, also on 4.61, ahead of Poland in bronze on 9.65.
Irish Independent
11-07-2025
- Sport
- Irish Independent
Sligo showjumper Paddy Reape helps Irish Under 18 team to win European gold
The Irish team of Sligo's Paddy Reape (Mr Rocky Blue (ISH), Tipperary's Tabitha Kyle (BP Goodfellas (ISH), Tipperary's Alice Wachman (Killarney) and Kilkenny's Emily Moloney (Temple Alice (ISH), along with reserve rider Jack Kent, moved into gold medal position following a flawless display in Germany on Wednesday. Ireland, managed by Denis Flannelly, produced another foot-perfect display in Thursday's medal decider, with three clear rounds keeping them on a score of 6.99 to secure the European team gold medal. The Netherlands claimed Silver on 12.79 while Belgium grabbed the Bronze medal on 20.60. Irish Horse Board Director General Alison Corbally said: 'This was a fantastic performance from the Irish Junior team to win the European Championship team gold medal. Huge congratulations to all of the team, their parents coaches and all those working behind the scenes. "It was also brilliant to see three Irish-bred horses on the gold medal winning Irish team and congratulations to their breeders, George McCullogh (Mr Rocky Blue (ISH), Kevin Babington (BP Goodfellas (ISH) and Susan McDonald (Temple Alice (ISH).' BREEDING: Mr Rocky Blue (ISH) – 2016 gelding by Chacoon Blue out of Ardeche Z by Artos Z. Breeder: George Jonathan Reape. Rider Paddy Reape. BP Goodfellas (ISH) – 2017 gelding by Stakkato Gold out of Goodwins Loyalty (ISH) by OBOS Quality 004. Breeder: Kevin Babington and GBBS Int. Ltd, Owner: GBBS Int. Ltd Temple Alice (ISH) – 2012 gelding by Foxglen Cruise Control out of Innishannon Shamrock (ISH) (TIH) by Rantis Diamond (ISH). Breeder: Susan McDonald Owner: Eddie Moloney and TSI Equestrian BP Rocket Man (ISH) 2017 Bay gelding By Stakkato Gold (HANN) Out of BP Quidy (ISH) By Quidam Junior I (KWPN) Bred by Austin Broderick.
Malaysian Reserve
08-07-2025
- Business
- Malaysian Reserve
$2.35 Billion by 2030: Why In Situ Hybridization Is Revolutionizing Molecular Diagnostics
DELRAY BEACH, Fla. , July 8, 2025 /PRNewswire/ — What's driving the shift to spatially resolved molecular analysis? The global in situ hybridization market, valued at USD 1.64 billion in 2025, is projected to reach USD 2.35 billion by 2030, growing at a CAGR of 7.4%. This growth is driven by the expanding role of ISH in precision medicine, laboratory-developed tests (LDTs), and spatial transcriptomics. Technological innovations—including multiplex ISH, high-sensitivity probes, and automation—are enabling more accurate, efficient, and spatially resolved gene expression analysis in both clinical and research settings. From oncology to neuroscience, ISH is paving the way for advanced diagnostics and next-generation therapeutic strategies. Download PDF Brochure: Why is ISH becoming a molecular game-changer? In Situ Hybridization methods such as FISH and RNA-ISH are increasingly used to detect patient-specific genetic markers at the single-cell level. These techniques offer greater specificity and spatial resolution than conventional assays. For instance, Molecular Instruments' HCR Pro RNA-ISH LDT (Feb 2025) now enables differentiation between psoriasis and atopic dermatitis based on biopsy-derived immunologic markers—transforming diagnostics for millions with chronic skin conditions. Key players like Precision for Medicine, Scantox, and Plus Therapeutics are leveraging ISH to support oncology, gene therapy, and neurodegenerative disease research, further embedding these tools in drug development pipelines and personalized treatment planning. What challenges does ISH solve? ISH technologies address a number of persistent issues in molecular and histopathological diagnostics: Enables precise spatial mapping of gene expression across accuracy in difficult diagnoses where IHC or sequencing alone falls shortSupports multi-target detection for robust biomarker discovery and translational research through integration of transcriptomic and proteomic analyses. For example, Roche's FDA-cleared VENTANA Kappa and Lambda Dual ISH mRNA assay (Jan 2025) enhances lymphoma subtype detection, representing a breakthrough in ISH-based molecular diagnostics. Where is adoption accelerating the fastest? While North America leads with the largest market share due to established infrastructure and funding, rapid growth is forecasted in the Asia Pacific, driven by rising cancer incidence, government funding, and diagnostic modernization. Key momentum drivers include: China, India, and Japan investing heavily in molecular pathology labs expanding ISH capabilities for cancer and infectious disease academic and CRO adoption of automated, scalable ISH platforms. Request Sample Pages : Who are the key leaders—and how are they gaining ground? The ISH market is consolidated, with 5 major players holding 60–65% of global market share: F. Hoffmann-La Roche Ltd (Switzerland): Leading in automated ISH diagnostics, including BenchMark ULTRA PLUS and FDA-cleared lymphoma probes. Danaher (US): Through Leica Biosystems, focuses on integrated automation and spatial biology (US): Dominant in ISH probes for oncology and cytogenetics under the VYSIS (US): RNAscope portfolio expansion to 70,000+ probes position it as a spatial transcriptomics Fisher Scientific (US): Offers a comprehensive suite of ISH instruments and consumables. Recent innovations include: Leica + Bio-Techne (Apr 2025): Automated RNAscope Multiomic LS for spatial + Molecular Instruments (Jan 2025): Launched HCR Pro RNA-ISH for high-sensitivity (Jan 2025): FDA-cleared B-cell ISH + Biocare (Mar 2025): NeoPATH Pro ISH system distributed in the US. What's the biggest challenge—and how do we overcome it? Despite promising advances, high costs and technical complexity remain barriers: Capital investment: ISH instruments like Ventana Benchmark Ultra cost ~$100, Multiplex probe kits and imaging services are costly, with per-slide fees reaching $113 or protocols: Require skilled personnel and careful costs: Advanced scanners such as Vectra can cost $200/hour to operate. Solutions must focus on: User-friendly automation platforms with streamlined optimization to reduce cost per initiatives to expand technical modular platforms for research and clinical users alike. What should diagnostics leaders be asking now? Not 'Is ISH useful?'—but rather: How can ISH improve our ability to detect spatial gene expression at single-cell resolution?Which multiplexing and automation technologies can scale with our diagnostics needs?Are our assays ready for regulatory validation and clinical deployment?How can we integrate transcriptomics and proteomics within one platform? Final Thought: In Spatial Precision, There Is Power. In Multiplexing, There Is Clarity. As genomics shifts toward spatial, multiplexed, and clinically actionable diagnostics, in situ hybridization is evolving from a research tool into a cornerstone of precision healthcare. It's not just about detection anymore—it's about localization, integration, and transformation of diagnostics. In the future of molecular medicine, personalization begins with precision—and ISH is leading the charge. Key Market Players: F. Hoffmann-La Roche Ltd (Switzerland), Danaher (US), Abbott (US), Bio-Techne (US), Thermo Fisher Scientific (US), Bioview (Israel), Biocare Medical (US), Agilent Technologies (US), QIAGEN (Germany), CytoTest Inc. (US), Genemed Biotechnologies (US), ZytoVision GmbH (Germany), Abnova (Taiwan) For more information, Inquire Now! Related Reports: Companion Diagnostics Market Immunohistochemistry Market Tissue Diagnostics Market Immuno Oncology Assays Market Cancer Diagnostics Market Get access to the latest updates on Top Companies in In Situ Hybridization and In Situ Hybridization Market Size About MarketsandMarkets™: MarketsandMarkets™ has been recognized as one of America's Best Management Consulting Firms by Forbes, as per their recent report. MarketsandMarkets™ is a blue ocean alternative in growth consulting and program management, leveraging a man-machine offering to drive supernormal growth for progressive organizations in the B2B space. 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Time of India
15-06-2025
- Politics
- Time of India
Andhra Deputy CM Pawan Kalyan enrolls son Mark Shankar Pawanovich at the International School of Hyderabad. The fees will make your jaw drop
In a significant personal decision, Andhra Pradesh Deputy Chief Minister Pawan Kalyan has admitted his eight-year-old son, Mark Shankar Pawanovich , to the International School of Hyderabad (ISH), located within the ICRISAT campus in Patancheru. As per a Deccan Chronicle report, this move follows a distressing incident a few months ago when Mark sustained burn injuries in an unfortunate fire accident while studying in Singapore. Concerned about his recovery and overall well-being, Kalyan brought his son back to India, choosing to prioritize Mark's medical attention and emotional comfort through proximity and parental care. This Friday, the actor-turned-politician paid a personal visit to the ICRISAT campus. During this trip, he completed formalities related to his son's admission, inspected the school facilities, and briefly stopped by the research center at the institute. Family sources told the news portal that the decision to keep Mark close to home was taken after careful consideration, particularly given the child's recent trauma. For Kalyan, who juggles his political responsibilities with family life, ensuring a safe and nurturing environment for his son was paramount. The International School of Hyderabad, known for its high academic standards and multicultural environment, seemed like the perfect fit. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Santa Ursula: Scholarships You Can Apply For (Start Now) College Scholarship | Google Search Search Now Undo Inside ISH: A Hub of Global Learning The International School of Hyderabad is a reputed day school offering English-medium education to students between the ages of 4 and 18. With an enrollment of over 400 students representing more than 22 countries, the institution prides itself on being an educational melting pot. While it predominantly serves international students, it also reserves a limited number of seats for Indian nationals. Notably, more than one-third of its faculty members hail from outside India, representing 12 different nationalities—making ISH stand out among Hyderabad's international schools. Established in 1981 under the aegis of the International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), ISH operates as a non-profit and holds a status comparable to institutions run by diplomatic missions. Its leadership includes the Director General of ICRISAT and a governing board that works closely with the school's Head of School to ensure seamless management and educational excellence. The school first introduced the IGCSE Cambridge curriculum in 2003 and awarded its first International Baccalaureate (IB) diplomas in 2007. Notably, ISH holds the distinction of being the first Indian school to receive international accreditation from the Council of International Schools (CIS) and continues to be recognized by both CIS and the New England Association of Schools and Colleges (NEASC). It was also the pioneer in offering the IB diploma in what is now Telangana. With a strong emphasis on academic rigor and university readiness, ISH sees a majority of its graduates admitted to top-tier universities, particularly in North America. Take A Look At The Sky High Fees However, this level of education comes at a steep cost. According to the school's website, the registration fee is Rs 83,000, the enrollment charge is a hefty Rs 8.3 lakh, and annual tuition varies between Rs 8.7 lakh and Rs 13.6 lakh, depending on the grade level. Balancing Work and Family On the professional front, Pawan Kalyan remains active in cinema. He is currently working on two films—They Call Him OG, a gritty gangster drama, and Ustad Bhagat Singh, adding yet another layer to his multifaceted life as a political leader, actor, and devoted father.
