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Yahoo
6 hours ago
- Health
- Yahoo
Hematologist Dissatisfaction with Current Warm Autoimmune Hemolytic Anemia (w-AIHA) Treatment Spurs Interest in Late-Stage Pipeline, According to Spherix Global Insights
Hematologists are poised to jump on new market entrants once available, as high unmet need and frustration with current treatment standards persist in w-AIHA. EXTON, PA, July 29, 2025 (GLOBE NEWSWIRE) -- According to new findings from Spherix Global Insights' syndicated Market Dynamix™ service, hematologists managing patients with warm autoimmune hemolytic anemia (w-AIHA) continue to face clinical complexity, a lack of clear treatment algorithms, and suboptimal outcomes across large segments of their patient population. w-AIHA is a rare hematologic condition in which the body's immune system produces antibodies (primarily IgG) that target and destroy red blood cells at normal body temperatures. It is the most common subtype of autoimmune hemolytic anemia, representing approximately 60–70% of AIHA cases. While the exact prevalence remains difficult to pinpoint, recent research estimates the annual incidence at 1–3 cases per 100,000 individuals in the US.1 Insights from a recent survey of 55 hematologists and 8 in-depth physician interviews reveal that nearly half of patients with w-AIHA are not optimally managed, and only one-quarter maintain stable hemoglobin levels above 10 g/dL. While steroids remain the default first-line treatment, physician satisfaction remains low, with many calling for steroid-sparing options that deliver longer-lasting control and address refractory disease. Hematologists also report significant logistical and clinical hurdles, including delayed referrals, reliance on emergency care for diagnosis, and poor insurance coverage contributing to suboptimal care. Comorbidities such as hypertension, obesity, and acute anemia further complicate management in an already fragile population. The future treatment landscape, however, may offer new hope. Physicians highlighted a strong interest in several late-stage pipeline therapies, including nipocalimab (Johnson & Johnson), rilzabrutinib (Sanofi), and ianalumab (Novartis), with each seen as potentially meaningful advances. Physicians approximate that nearly half of their patients may be candidates for at least one of these agents, citing excitement around novel mechanisms, potential for sustained efficacy, and ability to reduce steroid dependence. As hematologists await more definitive guidance and data, they remain aligned in their call for treatments that can deliver durable response, safety, and flexibility across varying levels of disease severity. The w-AIHA space is poised for disruption, but not without overcoming entrenched beliefs and real-world access barriers. Market Dynamix™ is an independent, data-driven service focused on understanding the evolving dynamics of specialty markets poised for disruption. Leveraging quantitative and qualitative research, the service evaluates current treatment approaches, unmet needs, and likely impact of pipeline agents over a three-to-five-year horizon. About Spherix Global Insights Spherix is a leading independent market intelligence and advisory firm that delivers commercial value to the global life sciences industry, across the brand lifecycle. The seasoned team of Spherix experts provides an unbiased and holistic view of the landscape within rapidly evolving specialty markets, including dermatology, gastroenterology, rheumatology, nephrology, neurology, ophthalmology, and hematology. Spherix clients stay ahead of the curve with the perspective of the extensive Spherix Physician Community. As a trusted advisor and industry thought leader, Spherix's unparalleled market insights and advisory services empower clients to make better decisions and unlock opportunities for growth. To learn more about Spherix Global Insights, visit or connect through LinkedIn. For more details on Spherix's primary market research reports and interactive dashboard offerings, visit or register here: NOTICE: All company, brand or product names in this press release are trademarks of their respective holders. The findings and opinions expressed within are based on Spherix Global Insight's analysis and do not imply a relationship with or endorsement of the companies or brands mentioned in this press release. CONTACT: Sarah Hendry, Hematology Franchise Head Spherix Global Insights 4848794284
India.com
05-07-2025
- Health
- India.com
World's Costliest Tear? One Drop from This Animal Can Neutralize 26 Snake Venoms, Help You Earn Lakhs
photoDetails english 2926996 Tears are more than just a response to emotion—they reflect complex feelings and serve vital biological roles. Whether from joy, grief, or irritation, tears protect our eyes, relieve stress, and connect us to others. From ancient beliefs to modern science, these small drops carry deep emotional and physiological significance. Ever wondered about the world's most valuable tear? Updated:Jul 05, 2025, 12:55 PM IST Ship of the desert 1 / 7 In Rajasthan's arid desert region, camels—long revered as the "ships of the desert"—have been essential for helping farmers travel across harsh terrains. Now, scientists at the National Research Centre on Camel (NRCC) in Bikaner have made a groundbreaking discovery: antibodies from camel tears and their immune system may help neutralise snake venom. This promising research could lead to more effective treatments for snakebite victims and improve the wellbeing of farmers who depend on camels. Echis carinatus sochureki 2 / 7 According to media reports, scientists at the National Research Centre on Camel (NRCC) conducted a series of experiments where they immunised dromedary camels (Camelus dromedarius) using venom from the saw-scaled viper (Echis carinatus sochureki), a highly venomous snake species. Blood serum 3 / 7 The researchers found that antibodies present in the camels' blood serum and tears effectively neutralised the venom's impact. Notably, they significantly reduced the venom's harmful effects, particularly those causing internal bleeding (hemorrhage) and blood clotting disorders (coagulopathy). Allergic reaction 4 / 7 Antibodies derived from camels showed stronger effects and caused fewer allergic reactions compared to traditional antivenoms made from horse immunoglobulin (IgG). Moreover, camel-based antivenoms are more efficient and less costly to produce, making them a promising alternative to the complex and expensive horse-derived options. Snakebite crisis 5 / 7 India faces a severe snakebite crisis, recording around 58,000 deaths and 1.4 lakh disabilities annually—the highest in the world. The NRCC's discovery of camel-derived antibodies offers hope for developing safer, more affordable, and easily producible treatments, especially benefiting rural populations where snakebites are frequent and access to timely medical care is limited. NRCC 6 / 7 This initiative marks a significant economic shift for camel-rearing communities in regions like Bikaner, Jaisalmer, and Jodhpur. The NRCC has partnered with local farmers, offering generous compensation in return for safe and efficient collection of camel tears and blood samples, encouraging greater participation and benefiting both science and livelihoods. Pharmaceutical firms 7 / 7 As per the report, pharmaceutical firms like the Serum Institute of India and other private drug manufacturers are developing business models centred around camel-derived antibodies. This innovation could help farmers earn an extra Rs 5,000 to Rs 10,000 per camel monthly, offering them a sustainable and scientifically promising source of income.
India.com
05-07-2025
- Health
- India.com
This is world's most expensive tear; one drop can neutralize 26 snake venoms, it is worth Rs..., it is of...
This is world's most expensive tear; one drop can neutralize 26 snake venoms, it is worth Rs..., it is of... Tears may seem like merely small drops of water but are quite meaningful and important. For centuries, people have talked about tears. People have used phrases like 'crocodile tears' to show that some tears are fake or false. But tears are not always about sadness or pretending. Tears can show feelings, tell stories, and can even have amazing health impacts. Do you know which is the world's most expensive tear? One drop of tear can… What makes camel's tear so powerful against snake venom? In Rajasthan's dry desert land, camels have always been known as the 'ship of the desert' because they help farmers commute long miles through tough lands. Now, these wonderful animals are revealing something even more astounding. Scientists at the National Research Centre on Camel (NRCC) in Bikaner have discovered that the antibodies derived from the camel tears and its immune system could be used to combat snake venom. This is an exciting finding that may eventually lead to improved treatments for victims of snakebites and also yield improved quality of life for farmers who raise camels. Who conducted the study revealing the medicinal power of camel tears? As per a Moneycontrol report, researchers from the NRCC staged a series of experiments in which they immunized camels (Camelus dromedarius) with venom from the saw-scaled viper (Echis carinatus sochureki), which is an extremely venomous snake species. Their findings indicated that antibodies from the camels' blood serum and tears provided effective neutralization of the effects of the venom; most importantly, the venom's effects related to hemorrhage and coagulopathy were greatly abated. Camel-based antibodies also had fewer allergy issues, and effects were more potent than those derived from traditional antivenoms made from horse immunoglobulin (IgG), which are expensive for production and complex to collect. Why is this tear considered the most expensive in the world? India is experiencing a serious snakebite crisis, with nearly 58,000 deaths per year and another 140,000 people with disabilities—the highest-burden worldwide. The NRCC's camel-derived antibodies could lead to lower-cost, safer, and easier-to-produce treatments. This is ultimately great for patients in rural areas, where snakebites are common and timely medical care is more difficult to obtain. This work shows economic transformation for camel-rearing groups in areas such as Bikaner, Jaisalmer, and Jodhpur. The NRCC has worked to convince local farmers to give them access to their camels for quick and safe collection of tears and blood samples; in exchange, farmers are compensated lavishly. According to the report, Pharmaceutical companies such as the Serum Institute of India and other private drug companies are building business models around the camel-derived antibodies, with estimates that farmers can cash additional income of Rs 5,000 to 10,000 per camel each month; this can give the farmers a new, sustainable, and scientifically lucrative source of cash.
Time of India
01-07-2025
- Health
- Time of India
Dedicated wards, test kits ready: Patna hospitals gear up to tackle dengue rise
1 2 3 4 Patna: With the district recording over twice the number of dengue cases till June this year as compared to the same period in 2024, hospitals have been directed to create dedicated wards and take other measures to prepare for a potential increase in the cases and other vector-borne diseases, as monsoon progresses. Patna district recorded 48 dengue cases by June 30, compared to around 20 during the same period the previous year. The district authorities anticipate that the number of cases will likely increase this year. Patna civil surgeon Dr Abinash Kumar Singh said that of the 48 dengue patients, 26 tested positive at private hospitals. "Preparation has already started for the prevention, testing and treatment of dengue. Around 10,000 combo kits (to detect both dengue virus NS1 antigen and IgG/IgM antibodies) have been procured, and will be given to the govt health facilities in the district. The hospitals have been asked to keep all required medicines, testing kits and mosquito nets ready for dengue patients," he said. The civil surgeon has directed the medical officers of the primary health centres to create two-bed dengue wards, the subdivisional hospitals to arrange for five-bed wards and govt hospitals to keep 10-bed wards ready. Nalanda Medical College and Hospital (NMCH)-Patna has been designated as the nodal centre for dengue in Patna, where a dedicated ward with 80 beds will be arranged. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Giao dịch CFD với công nghệ và tốc độ tốt hơn IC Markets Đăng ký Undo "At Patna Medical College Hospital, a 10-bed intensive care unit (ICU) will be created for dengue patients. The number of beds in dengue wards will be increased in hospitals as per requirement. Additionally, we have around 20 blood banks, including 14 private ones. The blood bank at Paras HMRI has the equipment to separate platelets," the civil surgeon told this newspaper. A health official said the dengue cases, however, peak around Sept-Oct. Around 250 dengue cases were being reported per day during peak time in Oct last year, he added. Patna district magistrate (DM) Thiyagarajan SM said all municipal officials have been asked to ensure preventive and cautionary measures to control dengue. He emphasised the need for vigilance during the rainy season, even though there was no current outbreak of dengue. The DM instructed the civil surgeon to keep rapid response teams active at all primary, urban primary and community health centres, besides referral hospitals. "Activities like intensive spraying of anti-larvae chemicals, house-to-house surveys, source reduction and awareness campaigns, including at schools, are being done. Large-scale promotion of 'Dos and Don'ts' is crucial," Thiyagarajan said, asking the municipal bodies to conduct fogging and ensure waterlogging is prevented. Active surveillance around confirmed dengue cases should be conducted to identify new patients, he told them. The DM directed all schools and colleges to follow the health advisories. "Students should be encouraged to wear clothes, covering most of their body. Educational institutions must maintain high standards of cleanliness and regularly spray anti-larvae chemicals (temephos) in drains," he said. Get the latest lifestyle updates on Times of India, along with Doctor's Day 2025 , messages and quotes!
Time of India
01-07-2025
- Health
- Time of India
With dengue cases doubling this yr from last, Patna hospitals gear up with dedicated wards
1 2 3 Patna: With the district recording over twice the number of dengue cases till June this year as compared to the same period in 2024, hospitals have been directed to create dedicated wards and take other measures to prepare for a potential increase in the cases and other vector-borne diseases, as monsoon progresses. Patna district recorded 48 dengue cases by June 30, compared to around 20 during the same period the previous year. The district authorities anticipate that the number of cases will likely increase this year. Patna civil surgeon Dr Abinash Kumar Singh said that of the 48 dengue patients, 26 tested positive at private hospitals. "Preparation has already started for the prevention, testing and treatment of dengue. Around 10,000 combo kits (to detect both dengue virus NS1 antigen and IgG/IgM antibodies) have been procured, and will be given to the govt health facilities in the district. The hospitals have been asked to keep all required medicines, testing kits and mosquito nets ready for dengue patients," he said. The civil surgeon has directed the medical officers of the primary health centres to create two-bed dengue wards, the subdivisional hospitals to arrange for five-bed wards and govt hospitals to keep 10-bed wards ready. Nalanda Medical College and Hospital (NMCH)-Patna has been designated as the nodal centre for dengue in Patna, where a dedicated ward with 80 beds will be arranged. "At Patna Medical College Hospital, a 10-bed intensive care unit (ICU) will be created for dengue patients. The number of beds in dengue wards will be increased in hospitals as per requirement. Additionally, we have around 20 blood banks, including 14 private ones. The blood bank at Paras HMRI has the equipment to separate platelets," the civil surgeon told this newspaper. Patna district magistrate (DM) Thiyagarajan SM said all municipal officials have been asked to ensure preventive and cautionary measures to control dengue. He emphasised the need for vigilance during the rainy season, even though there was no current outbreak of dengue. The DM instructed the civil surgeon to keep rapid response teams active at all primary, urban primary and community health centres, besides referral hospitals. "Activities like intensive spraying of anti-larvae chemicals, house-to-house surveys, source reduction and awareness campaigns, including at schools, are being done. Large-scale promotion of 'Dos and Don'ts' is crucial," Thiyagarajan said, asking the municipal bodies to conduct fogging and ensure waterlogging is prevented. Active surveillance around confirmed dengue cases should be conducted to identify new patients, he told them. The DM directed all schools and colleges to follow the health advisories. "Students should be encouraged to wear clothes, covering most of their body. Educational institutions must maintain high standards of cleanliness and regularly spray anti-larvae chemicals (temephos) in drains," he said. Get the latest lifestyle updates on Times of India, along with Doctor's Day 2025 , messages and quotes!
