Latest news with #JohnIoannidis
Daily Mail
3 days ago
- Health
- Daily Mail
'Aggressive mandate' of Covid vaccines was 'probably a bad idea' as new study reveals WHO mandated blanket vaccination saved 'fewer lives than expected'
The 'aggressive mandate' of Covid vaccines has been blasted as a 'bad idea' by experts after a new study revealed it saved less lives than predicted. The World Health Organisation (WHO) claimed that the jabs prevented 14.4million deaths just in the first year, with some estimating up to 20million. However, new research by Stanford University and Italian doctors revealed the true number is closer to 2.5million. The team estimated that nine out of ten prevented deaths were in the over-60s, while it only saved 299 people under the age of 20 and 1,808 youngsters between 20 and 30 globally. John Ioannidis, Professor of Medicine at Stanford University and the first author, said: 'Targeting the populations who would get the vast majority of the benefit and letting alone those with questionable risk-benefit and cost-benefit makes a lot of sense. 'Aggressive mandates and the zealotry to vaccinate everyone at all cost were probably a bad idea.' Overall 5,400 people needed to be vaccinated to save one life but in the under-30s this figure rose to 100,000 jabs, the paper suggests. The over-70s made up nearly 70 per cent of the lives saved, while the 60 to 70s accounted for a further 20 per cent. Meanwhile, under-20s made up just 0.01 per cent of lives saved and 20 to 30s were 0.07 per cent Researchers concluded that although vaccines had a 'substantial benefit' on global mortality, it was 'mostly limited' to older people. More than 23 billion doses of the vaccine have been administered since its roll out in 2021. But there have been growing concerns over its harms, particularly for young people, and how it may not be worth it for a population who is at the lowest risk of death. US scientists from Yale University identified an alarming syndrome linked to mRNA jabs, those made by the likes of Pfizer and Moderna. Called 'post-vaccination syndrome', the condition appears to cause brain fog, dizziness, tinnitus and exercise intolerance, the researchers reported. Some sufferers also show distinct biological changes, including differences in immune cells and the presence of coronavirus proteins in their blood, years after taking the shot. The condition is also said to increase the risk of reawakening a dormant virus called Epstein-Barr, which can cause flu-like symptoms, swollen lymph nodes and nerve issues. In June, manufacturers added warnings for myocarditis and pericarditis - a potentially dangerous inflammation of the heart muscle It comes as more than 17,000 Brits now claim they have been injured or have had loved ones killed by a Covid jab, according to the latest Government data.
Telegraph
3 days ago
- Health
- Telegraph
Covid vaccines ‘saved far fewer lives than first thought'
Covid vaccines saved far fewer lives than first thought, a major new analysis has concluded, with researchers criticising 'aggressive mandates'. In 2024, the World Health Organisation (WHO) claimed that jabs prevented the deaths of 14.4 million globally in the first year alone, with some estimates putting the figure closer to 20 million. However, new modelling by Stanford University and Italian researchers suggests that while the vaccine did undoubtedly save lives, the true figure is 'substantially more conservative' and closer to 2.5 million worldwide over the course of the entire pandemic. The team estimated that nine of 10 prevented deaths were in the over-60s, with jabs saving just 299 youngsters aged under 20, and 1,808 people aged between 20 and 30 globally. Overall 5,400 people needed to be vaccinated to save one life but in the under-30s this figure rose to 100,000 jabs, the paper suggests. Researchers criticised 'aggressive mandates and the zealotry to vaccinate everyone at all cost', adding that the findings had implications for how future vaccine rollouts are handled. John Ioannidis, Professor of Medicine at Stanford University and the first author, said: 'I think early estimates were based on many parameters having values that are incompatible with our current understanding. 'In principle, targeting the populations who would get the vast majority of the benefit and letting alone those with questionable risk-benefit and cost-benefit makes a lot of sense. 'Aggressive mandates and the zealotry to vaccinate everyone at all cost were probably a bad idea.' Since 2021, more than 13 billion Covid-19 vaccine doses have been administered. But there have been mounting concerns that vaccines could be harmful for some people, particularly the young, and that the risk was not worth the benefit for a population at little risk from Covid. More than 17,500 Britons have applied to the Government's vaccine damage payment scheme believing they or loved ones were injured by the jab. In June, manufacturers added warnings for myocarditis and pericarditis to Covid-19 messenger RNA (mRNA) vaccines' prescribing information. For the new study, experts used worldwide population data, alongside vaccine effectiveness and infection fatality rates, to estimate how many people died from a Covid infection before or after the periods of vaccination. The team believes earlier modelling may have used overly pessimistic infection fatality rates and overly optimistic vaccine effectiveness, while failing to consider how quickly protection waned. Based on fewer assumptions Earlier studies may also have underestimated how many people had already been unknowingly infected by the time they had the vaccine. Dr Angelo Maria Pezzullo, researcher in general and applied hygiene at the Catholic University of the Sacred Heart, in Milan, said: 'Before ours, several studies tried to estimate lives saved by vaccines with different models and in different periods or parts of the world, but this one is the most comprehensive because it is based on worldwide data. it also covers the omicron period. 'It also calculates the number of years of life that was saved, and it is based on fewer assumptions about the pandemic trend.' The team calculated that around 14.8 million life-years were saved, one life-year saved per 900 vaccine doses administered. Researchers concluded that although vaccines had a 'substantial benefit' on global mortality, it was 'mostly limited' to older people. The over-70s made up nearly 70 per cent of the lives saved, while the 60 to 70s accounted for a further 20 per cent. In contrast, under-20s made up just 0.01 per cent of lives saved and 20 to 30s were 0.07 per cent. Professor Stefania Boccia, of the Catholic University of the Sacred Heart, added: 'These estimates are substantially more conservative than previous calculations that focused mainly on the first year of vaccination, but clearly demonstrate an important overall benefit from Covid-19 vaccination over the period 2020-2024. 'Most of the benefits, in terms of lives and life-years saved, have been secured for a portion of the global population who is typically more fragile, the elderly.' Sir David Davis, the former Brexit secretary who fought against vaccine mandates, said: 'Frankly it's a good cautionary tale that if we have another pandemic we should be far more clinical about the risk-benefit ratio. 'We knew pretty quickly who the most susceptible groups were and we should have focused very strictly on them, rather than placing people who were at little risk in hazard's way. 'The level of aggression of trying to force people to become vaccinated and shutting down people who were raising concerns, the reasons for those concerns are all validated in this report.'
South China Morning Post
12-02-2025
- Science
- South China Morning Post
Far more top cited US scientists have papers retracted than Chinese peers: paper
More leading American scientists have had papers retracted than the number of Chinese, British, Japanese and German researchers combined, according to a study published in PLOS Biology on January 30. Among scientists included in the Stanford Elsevier career-long list of the world's top 2 per cent of scientists last year, some 2,322 US-affiliated elite researchers have had papers retracted in their career, compared with 877 top scientists affiliated with China. Rounding out the top five are Britain with 430 researchers having papers retracted, Japan (362) and Germany (336). 01:49 US declines to sign international declaration on artificial intelligence US declines to sign international declaration on artificial intelligence The authors make clear that retractions, while increasingly common, 'still account for a small minority of published papers' and that a paper can be retracted for a variety of reasons. 'Not every retraction is a sign of misconduct,' John Ioannidis, an epidemiologist at Stanford University who led the study, told Nature News on January 31. 'But it is important to have a bird's-eye view, across all scientific fields, people who are most influential in science.' The data comes from the Retraction Watch Database, a site focused on tracking and recording the withdrawal of academic papers around the world. It was launched in August 2010, having been created and maintained by the scientific monitoring organisation Retraction Watch. Until August 15 last year, the database had more than 55,000 retraction records covering a range of disciplines.
