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Iambic Taps Lambda for Increased AI Compute as it Develops the Next Generation of Enchant, a Breakthrough AI Molecular Property Prediction Model for Drug Discovery
Iambic Taps Lambda for Increased AI Compute as it Develops the Next Generation of Enchant, a Breakthrough AI Molecular Property Prediction Model for Drug Discovery

Business Wire

time2 days ago

  • Business
  • Business Wire

Iambic Taps Lambda for Increased AI Compute as it Develops the Next Generation of Enchant, a Breakthrough AI Molecular Property Prediction Model for Drug Discovery

SAN JOSE, Calif.--(BUSINESS WIRE)--Lambda, the GPU cloud company founded by AI engineers, today announced that Iambic Therapeutics, a clinical-stage life science and technology company developing novel medicines using its AI-driven discovery and development platform, has selected Lambda to provide an NVIDIA HGX B200 cluster to support the training of Enchant, its industry-leading model for molecular property prediction. Iambic's Enchant is a breakthrough multi-modal transformer model for predicting clinical and preclinical endpoints related to the drug discovery and development process. Enchant enables researchers to determine the viability of new drug molecules and make high-confidence predictions where data is most sparse, helping address the critical real-world challenge of understanding how novel drug candidates may affect a patient while still in the earliest stages of discovery. Iambic's recently announced Enchant v2 provides accurate predictions for dozens of biological, physiochemical, pharmacokinetic, metabolic, safety, and other properties essential for clinical success. 'With the release of Enchant v2, we demonstrated both the model's accuracy and scalability and we believe we can rapidly build on these gains through model scale alone,' said Matt Welborn, PhD, Iambic's VP of Machine Learning. 'We are expanding our successful relationship with Lambda to an NVIDIA HGX B200 cluster, which will accelerate this opportunity and the breadth of pre-clinical and clinical endpoints Enchant can predict, increasing the likelihood of a molecules' success in human studies and the efficiency of drug development.' Enchant's high-confidence predictions enable multi-parameter optimization for the design of potentially more effective medicines, program prioritization, and the design of clinical trials for the potentially rapid translation of novel medicines. Iambic researchers also demonstrated that in some cases Enchant can be a better predictor of in vivo drug clearance than in vitro experiments – a key advancement as regulators look for drug developers to broaden their use of in silico testing. Today, Enchant is the leading model in the field based on performance benchmarks across diverse molecular property prediction tasks. 'We're thrilled to deepen our partnership with Iambic, a leader in AI-driven drug discovery,' said Robert Brooks IV, Founding Team and VP, Revenue. 'By leveraging Lambda's 1-Click Clusters for rapid testing and validation, Iambic was able to seamlessly scale to an NVIDIA HGX B200 cluster to accelerate breakthroughs in life sciences.' To learn more about Lambda's cloud offerings for AI training and inference, click here. About Iambic's AI-Driven Discovery Platform The Iambic AI-driven platform was created to address the most challenging design problems in drug discovery, leveraging technology innovations such as Enchant (multimodal transformer model that predicts clinical and preclinical endpoints) and NeuralPLexer (best-in-class predictor of protein and protein-ligand structures). The integration of physics principles into the platform's AI architectures improves data efficiency and allows molecular models to venture widely across the space of possible chemical structures. The platform enables identification of novel chemical modalities for engaging difficult-to-address biological targets, discovery of defined product profiles that optimize therapeutic window, and multiparameter optimization for highly differentiated development candidates. Through close integration of AI-generated molecular designs with automated chemical synthesis and experimental execution, Iambic completes design-make-test cycles on a weekly cadence. About Iambic Therapeutics Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at About Lambda Lambda was founded in 2012 by AI engineers with published research at the top machine learning conferences in the world. Our goal is to become the #1 AI compute platform serving developers across the entire AI development lifecycle. We enable AI engineers to easily, securely and affordably build, test and deploy AI products at scale. Our product portfolio spans from on-prem GPU hardware to hosted GPUs in the cloud. Lambda's mission is to create a world where access to computation is as effortless and ubiquitous as electricity.

ZULI Builds on the 'Lambada' Universe with New EP 'Care'
ZULI Builds on the 'Lambada' Universe with New EP 'Care'

CairoScene

time6 days ago

  • Entertainment
  • CairoScene

ZULI Builds on the 'Lambada' Universe with New EP 'Care'

Built between Cairo and Berlin, ZULI's Care dives deeper into the soundscape of 2024's Lambda, blending R&B mutations, field recordings, and ambient fragments into four dense, layered tracks. Jun 22, 2025 Berlin-based Egyptian producer ZULI releases 'Care', a four-track EP that expands the his 2024's LP 'Lambda'. Developed between Cairo and Berlin, the release includes two original tracks and two reimaginings, offering a study in melancholy, detail, and immersive storytelling. The lead track, 'Care', opens with a field recording of ZULI tapping an unplugged guitar. A sudden street fight in Cairo, accidentally captured in the background, forms part of its atmospheric core. The result is a piece equally rooted in restraint and intensity. 'Elysian Blue' continues the textural approach of 'Lambda', using minimalist melody and drifting ambience to conjure emotional residue. The EP also includes a remix of 'Ast' (feat. Coby Sey), with Berlin's Ludwig Wandinger reshaping its R&B DNA into something soulful, surreal, and dream-like.

The serverless shift: Scaling smarter with fewer resources and no infrastructure bloat
The serverless shift: Scaling smarter with fewer resources and no infrastructure bloat

Hans India

time11-06-2025

  • Business
  • Hans India

The serverless shift: Scaling smarter with fewer resources and no infrastructure bloat

In today's fast-paced digital era, agility, scalability, and efficiency have become critical imperatives rather than luxuries. Serverless computing, which eliminates infrastructure management and allows developers to focus purely on delivering value, is emerging as a powerful response to these demands. At the forefront of this transformation is Anil Kumar Manukonda, a cloud innovator who has been instrumental in architecting high-performance, cost-effective solutions for modern enterprises. 'Serverless is more than a trend—it's a mindset shift,' says Anil. 'It empowers teams to build smarter, faster, and with fewer operational burdens. The true value lies in accelerating innovation without compromising reliability or security.' Anil's pioneering work includes the design of a mission-critical, event-driven data ingestion pipeline using AWS Lambda, Kinesis Data Streams, and DynamoDB. The system now processes over 200,000 events per hour with sub-250ms latency—a dramatic improvement over the EC2-based batch system it replaced. 'We achieved a 50% reduction in processing time while completely eliminating downtime,' he explains. By implementing provisioned concurrency, cold-start latency dropped by 90%, ensuring consistent performance even during peak traffic. His leadership extended to transforming a legacy reporting microservice into a serverless REST API with API Gateway, Lambda, and RDS Proxy. The result? A 300% increase in throughput and $120,000 in annual cloud savings. Anil also introduced a centralized governance framework using Terraform modules and AWS Config Rules, enabling consistent, compliant deployments across five critical business applications. The impacts are measurable: 30% higher developer productivity, 80% fewer budget overruns, and a 40% cut in incident response time—thanks in part to automation using SNS and DynamoDB streams. One of his most ambitious projects involved rearchitecting an order processing system with SQS and Lambda, scaling it to 250,000 orders per day and reducing fulfillment times from five minutes to just 30 seconds. 'Serverless lets you scale from zero to massive workloads with grace,' Anil notes. 'But success also means solving new challenges—latency, state management, and security.' His solutions include hybrid warming strategies and IAM automation across multi-account AWS environments. Anil's contributions extend beyond the workplace. He's the author of influential publications like Designing Highly Available and Scalable Web Applications Using Azure Functions and Automating Infrastructure Provisioning Using Terraform. He sees the future of cloud computing in AI-driven serverless functions, edge-native services, and function mesh architectures. 'Serverless is no longer just about cost savings,' he emphasizes. 'It's about enabling resilient, intelligent, and scalable architectures that redefine what's possible.' Through vision, execution, and thought leadership, Anil Kumar Manukonda is not just navigating the serverless frontier—he's charting its course.

Aligned and Lambda Partner to Power Next-Generation AI Infrastructure
Aligned and Lambda Partner to Power Next-Generation AI Infrastructure

Associated Press

time07-05-2025

  • Business
  • Associated Press

Aligned and Lambda Partner to Power Next-Generation AI Infrastructure

DALLAS, May 07, 2025 (GLOBE NEWSWIRE) -- Aligned Data Centers, a leading technology infrastructure company offering innovative, sustainable and adaptive Scale Data Centers and Build-to-Scale solutions for global hyperscale and enterprise customers, today announced a partnership with Lambda, the AI Developer Cloud, to provide customers with data center infrastructure and an AI cloud platform ready to sustainably accelerate their AI growth. Lambda will occupy Aligned's newest Dallas-Fort Worth area facility, DFW-04, which will be designed to be a liquid-cooled data center capable of supporting the highest-density Graphics Processing Units (GPUs). 'We're proud to partner with Lambda to support the buildout of its GPU cloud infrastructure, accelerated by NVIDIA, for AI deployments, which is transforming how AI developers innovate and businesses utilizing AI models operate,' states Andrew Schaap, CEO of Aligned. 'Particularly in Dallas, where demand for AI computation space has spiked interest in a growing market, combining a GPU cloud built specifically for AI workloads with an AI-ready data center designed with liquid cooling technologies capable of supporting the highest-density environments will be a game changer.' Aligned is at the forefront of building and operating adaptive data centers that future-proof IT infrastructure and provide seamless flexibility for transitions between a variety of deployments ranging from enterprise applications, to cloud, and high-density AI implementation. The company's ultra-scalable and flexible Adaptive Modular Infrastructure (AMI) and innovative air, liquid, and hybrid cooling solutions future-proof IT deployments, mitigate IT obsolescence, and maximize asset lifespan. While committing to sustainability as a core pillar of its customer-focused business strategy, the company has been an industry leader in advancing data center energy efficiency and cooling technologies for more than a decade, including its patented and award-winning Delta3™ air-cooled system. Aligned's patent-pending DeltaFlow™ liquid cooling system delivers unparalleled performance for AI innovation, supporting virtually any density and GPU cloud requirement. The company's scalable, sustainable infrastructure is enabling next-generation AI workloads. Aligned's partnership with Lambda exemplifies its dedication to leading AI service providers. Lambda's AI Developer Cloud is trusted by world-renowned AI engineers and industry pioneers who have shaped modern artificial intelligence. The organization's customers include some of the most successful and best-known technology companies, trillion-dollar capitalization enterprises, academic and research institutions in the world, as well as AI startups. The partnership with Aligned will see Lambda's AI Cloud platform integrated into the company's new DFW-04 data center, which is currently under construction in Plano, Texas. A determinative factor of this alliance is that Aligned's seamless and adaptive infrastructure for next-gen AI will easily support infrastructure accelerated by NVIDIA Blackwell and NVIDIA Blackwell Ultra, as well as the future generations of AI platforms. 'With its unrelenting focus on driving disruptive innovation in data center design, energy efficiency and cooling, Aligned is the ideal partner to help Lambda build large, flexible space that meets the AI demands of today and tomorrow,' comments Lambda VP, Data Center Infrastructure, Ken Patchett. 'Deploying AI at scale is no easy feat, and Aligned's ability to rapidly deliver AI-ready infrastructure, along with its passion for supporting customers with a consistently high-touch, world-class experience, is instrumental to meet the aggressive scale, quality and speed standards Lambda sets for its public and private deployments.' About Aligned Data Centers Aligned Data Centers is a leading technology infrastructure company offering innovative, sustainable, and adaptive Scale Data Centers and Build-to-Scale solutions for global hyperscale and enterprise customers. Our intelligent infrastructure allows densification and vertical growth within the same footprint, enabling customers to scale up without disruption, all while maintaining industry-leading Power Usage Effectiveness (PUE). By reducing the energy, water and space needed to operate, our data center solutions, combined with our patented cooling technology, offer businesses a competitive advantage by improving sustainability, reliability, and their bottom line. For more information, visit and connect with us on X, LinkedIn and Facebook. About Lambda Lambda was founded in 2012 by AI engineers with published research at the top machine learning conferences in the world. Our GPU cloud and on-prem hardware enables AI developers to easily, securely and affordably build, test and deploy AI products at scale. Lambda's mission is to accelerate human progress with ubiquitous and affordable access to computation. One person, one GPU. Press and Analyst Inquiries Jennifer Handshew for Aligned Data Centers [email protected] +1 (917) 359-8838 Press Contact for Lambda [email protected] A photo accompanying this announcement is available at A video accompanying this announcement is available at

Cuomo was a same-sex marriage champion. He's not courting LGBTQ+ votes now.
Cuomo was a same-sex marriage champion. He's not courting LGBTQ+ votes now.

Yahoo

time06-05-2025

  • Politics
  • Yahoo

Cuomo was a same-sex marriage champion. He's not courting LGBTQ+ votes now.

NEW YORK — Andrew Cuomo counts same-sex marriage among his top accomplishments as governor, but he's not targeting LGBTQ+ voters in his bid for New York City mayor. Cuomo, the front-runner in the Democratic primary, has charted his path to political redemption through Black churchgoers and Jewish centrists for whom public safety and antisemitism are chief concerns. He's taken a Rose Garden approach to campaigning and limited his appearances, which has contributed to cutting out crucial Democratic clubs that help drive LGBTQ+ voters to the polls. Most notably, the former governor skipped a mayoral forum cohosted by the Stonewall Democratic Club of NYC, Lambda Independent Democrats of Brooklyn and other LGBTQ+ clubs in March. And he declined to partake in the clubs' candidate questionnaires and interviews. 'We interpreted it to mean that the LGBTQ community doesn't mean jack shit to him,' said Joe Jourdan, Lambda's president. 'Ignoring Lambda and Stonewall both is about as subtle as an atom bomb.' Aside from Lambda and Stonewall, the Jim Owles Liberal Democratic Club has taken umbrage as well. In recent weeks, all three clubs have voted to keep Cuomo off their slates and are advising New Yorkers against including him at all on their ranked choice ballots this June. They've endorsed more left-leaning candidates, including City Council Speaker Adrienne Adams, City Comptroller Brad Lander and state Assemblymember Zohran Mamdani. To be sure, the club leaders weren't Cuomo fans before the endorsement process. They say that he dodges venues where he may face tough questions and that they're assessing him on his full record. They've also accused him of inflating his advocacy for LGBTQ+ New Yorkers and allege he's no ally now as transgender rights are under attack by the Trump administration. 'It's really troubling that he has hired people who worked against trans rights, that he has not engaged with any of the modern LGBTQ issues that matter in 2025 and that he's still relying on a victory from over a decade ago to claim he's standing with our movement,' Stonewall President Gabriel Lewenstein said in an interview, referencing how Cuomo's campaign treasurer worked for an anti-trans group. Cuomo's decision to appeal to a broader swath of Democrats through law-and-order and economic messaging — with little focus on LGBTQ+ rights — reflects a broader shift among establishment Democrats away from culture war issues after last year's election. The former governor appeared to agree with labor leader Sean O'Brien in a recent podcast that focusing on 'social justice' priorities hurt the Democratic Party. Still, advancing gay rights is part of Cuomo's political legacy. He signed the Marriage Equality Act into law in 2011, making New York the largest state at the time to allow gay and lesbian residents to wed — four years before the U.S. Supreme Court effectively legalized same-sex marriage nationwide. He made combating HIV and AIDS a priority, advanced the Gender Expression Non-Discrimination Act and signed legislation to ban so-called conversion therapy. Cuomo also backed a law ensuring those who attack gay people can't claim they panicked over the person's sexual identity. 'We need marriage equality in every state in this nation,' Cuomo said in 2011 at an Empire State Pride Agenda gala, urging the rest of the country to follow New York's lead. 'Otherwise, no state really has marriage equality, and we will not rest until it is a reality.' The former governor is seeking a comeback in New York City after resigning in Albany four years ago amid allegations of sexual misconduct. He is seizing an opening left by the politically weakened incumbent, Mayor Eric Adams, who was beset by since-dropped federal fraud charges. Cuomo's campaign and its allies say he has built a diverse coalition that includes LGBTQ+ New Yorkers. 'Andrew Cuomo is talking directly to voters. His path to victory doesn't run through activist clubs,' said Democratic strategist Jon Reinish, a Cuomo supporter and fundraiser. 'The community knows what he's done. The community knows they have no greater champion.' Cuomo campaign spokesperson Esther Jensen said the former governor will win LGBTQ+ votes citywide 'because New Yorkers know Andrew Cuomo doesn't just pay lip service to the LGBTQ community issues, he delivers.' His stump speeches to receptive audiences, including labor unions that have endorsed him, do not omit mentions of the Marriage Equality Act, but they don't linger on it either. Instead, he uses themes more broadly appealing to moderate and centrist voters, painting himself as the experienced leader who will wipe away a dystopian landscape of homelessness, shuttered storefronts and random violence. 'He wants Eric Adams voters in Southeast Queens. He's going to every church in Brooklyn that he could get into,' said Allen Roskoff, the gay rights activist who leads the Jim Owles club. 'He knows where he's going to get his votes, and he has other things he wants to say. He wants to give a message that's more law-and-order.' Roskoff said he remembers Cuomo for his 'heroic' push to legalize same-sex marriage but also as the young aide who, while campaigning for his father, Mario Cuomo, was accused of slurring political rival Ed Koch in the 1977 mayoral primary. The former governor and his team have denied he's behind the 'Vote for Cuomo, Not the Homo' slogans. Koch went on to endorse Andrew Cuomo for governor in 2010. 'Most of the organized gay community is not with him,' Roskoff said. 'He has the typical Boss Tweed-type gays with him.' Democratic consultant Chris Coffey, who advises the Cuomo campaign, argued otherwise. He lauded the then-governor for building families by ushering in same-sex marriage and making gestational surrogacy possible for same-sex couples. 'He used his political capital to get it done. And it was a really, really, really big deal,' Coffey said. 'The fact is, my husband and I got married because we were able to thanks to Governor Cuomo. There are thousands of gay and lesbian families across the city that have benefited. That is the point of government.' Among Cuomo's highest-profile supporters is Rep. Ritchie Torres, the first gay Afro-Latino elected to Congress. 'Governor Cuomo succeeded where others failed — delivering marriage equality in New York long before it became the law of the land,' Torres told POLITICO. 'His success in advancing LGBTQ equality remains unequaled in New York City.' Cuomo enjoys a sizable lead over his more progressive rivals in public polling. But amid an effort encouraging voters to opt against him — known as DREAM, or 'Don't Rank Evil Andrew for Mayor' — LGBTQ+ political club members are spreading the word that the crowded Democratic field includes allies ready to fight today's fight. They include Adrienne Adams, Lander and Mamdani. 'The leader of New York City should be ready to stand up for all New Yorkers,' Lewenstein of Stonewall said. 'And if you're afraid to do that, it's a problem.'

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