Latest news with #Latent
Business Wire
22-07-2025
- Business
- Business Wire
Introducing Latent-X, a Frontier Generative AI Model for Protein Binder Design Accessible via No-Code Platform for Push-Button Protein Design
LONDON & SAN FRANCISCO--(BUSINESS WIRE)--Today, Latent Labs is launching Latent-X, a frontier AI model for push button protein design, outperforming competing models under identical laboratory conditions. The model is available for early access on Latent's no-code AI protein design platform, where users can upload protein targets and generate cyclic peptides and mini-binders directly in the browser. Through the platform, users can generate, explore, and score binder designs, selecting top-ranked structures for further lab testing. The platform includes a free tier for both commercial and non-commercial users. Sign up is available at Latent Labs is a frontier AI lab working to transform the expensive, labor intensive, and high failure rate processes of drug discovery into automated drug design. Traditional drug discovery requires screening millions of random molecules—a process where hit rates are typically well below 1% and each experiment takes months and costs thousands of dollars. With Latent-X, drug designers can generate high-confidence binders with the push of a button, achieving what would typically require testing millions of candidates by testing as little as 30 candidates per target. AI models have recently enabled solutions to previously insurmountable technical challenges in biology. With generative models, frontier AI can go beyond predicting structures to creating new sequences and structures of candidate drugs. "We envision a future where effective therapeutics can be designed entirely in a computer, much like how space missions or semiconductors are designed today," said Simon Kohl, CEO and founder of Latent Labs. "Our platform empowers scientists with lab-validated protein binder design at their fingertips, whether they're experts or new to AI-powered drug design, and without needing AI infrastructure. This is the first step on our mission toward making biology programmable in order to make drug design instantaneous." Latent-X generates functional, high affinity de novo binders with breakthrough laboratory performance. In extensive wet lab experiments across 7 therapeutic targets, Latent-X achieved 91-100% hit rates for macrocycles and 10-64% hit rates for mini-binders. The model delivered picomolar binding affinities for mini-binders and single-digit micromolar affinities for macrocycles, with generated binders showing strong target specificity. In head-to-head experimental comparisons, Latent-X exceeded the prior state-of-the-art, outperforming existing generative tools in both in silico evaluations and laboratory validation. Macrocycles are a sought after drug modality for their potential oral deliverability, with their compactness promising tissue permeability while retaining specificity. Mini-binders are a versatile new binder modality that offers high specificity in a flexible format. Full results are available in our technical report: The Latent Labs Platform allows users to access the state of the art in protein binder design in an intuitive platform for target upload, hotspot selection, binder design, and computational ranking. The platform features structure visualization, predicted structure overlays, and computational metric rankings allowing to replicate the AI workflows used to generate our successfully lab-validated binders. Latent-X is a general purpose frontier model that creates binders from scratch for unseen or previously untargeted proteins, solving the geometric puzzle of binding at the all-atom level. The model generates designs over 10x faster than previous methods and co-samples sequence and structure simultaneously, allowing for computational experimentation within seconds. Latent-X generalizes beyond nature's repertoire by generating all-atom binder structures that obey atomic-level biochemical rules, opening doors to other therapeutic modalities that depend on target-specific binding—nanobodies and antibodies being prime examples. The company is now open to partnerships to bring these expanded capabilities to new drug applications. Only five months ago Latent Labs announced its $50M funding round co-lead by Radical Ventures and Sofinnova Partners, with participation by Google's Chief Scientist Jeff Dean, Anthropic's CEO Dario Amodei and Eleven Labs' CEO Mati Staniszewski. The team consists of former AlphaFold 2 co-developers, ex-DeepMind team leads, and brings rich experience from Microsoft, Apple, Stability AI, Exscientia, Mammoth Bio, Altos Labs and Zymergen.
Time of India
08-07-2025
- Entertainment
- Time of India
'Deepika Padukone ke saath aisa...': Apoorva Mukhija recalls her parents' reaction during 'India's Got Latent' controversy
Apoorva Mukhija , the popular content creator and actress also known as The Rebel Kid, recently spoke about how her parents reacted when she found herself caught up in a huge controversy. After appearing on Samay Raina's show 'India's Got Latent' in February, Apoorva faced unexpected trouble that led to multiple FIRs being filed against her. Now, she has opened up about how her family handled the tense situation. How it all started It all began when Apoorva featured on an episode of 'India's Got Latent'. The show landed in hot water after YouTuber Ranveer Allahbadia asked an inappropriate 'parents' sex' question to a contestant. The remark was slammed by viewers as distasteful and offensive. Soon, the backlash grew and turned serious, with several FIRs registered against Apoorva. Here's how her parents reacted Months later, Apoorva opened up about the matter during a chat with director Farah Khan on her YouTube channel. She revealed what her parents told her at the time. Apoorva shared, "Mujhe kehte the, 'Koi baat nahi, aisa hota rehta hai. Hum dekhte the ki Deepika Padukone ke saath aisa ho raha hai. Ab tu bhi toh…'" Their words meant a lot to her. Even though they were clearly stressed, they didn't show it directly. Instead, they compared her situation to Deepika Padukone's — saying it was something that happens even with top stars. This light, supportive approach helped Apoorva deal with all the stress that came with the controversy. Thought it was just a joke Farah also asked Apoorva how she first reacted when she heard there were complaints and backlash against 'India's Got Latent'. The 23-year-old admitted she didn't believe it at first. She said, "Mujhe toh laga mazak ho raha hai, aisa ho hi nahi sakta. Ek din toh main hass rahi thi, ki yeh sab log pagal ho gaye hain. Aisa ho nahi sakta. Jhoot bol rahe hain. Phir uske baad main bahut royi." Forced to leave her flat The problems didn't stop online. Apoorva revealed that after the controversy, she was asked to leave her apartment in Mumbai. When she went hunting for a new place, a building owner recognised her from the 'Latent' row and decided to blacklist her from the entire building. Back on screen with 'The Traitors ' Even after all this, Apoorva didn't let it stop her work. She was recently seen on the reality show 'The Traitors'. Fans still know her best as The Rebel Kid, loved for her funny and relatable videos about everyday life.
India Today
07-07-2025
- Entertainment
- India Today
Grateful that it happened to me: Apoorva Mukhija on India's Got Latent controversy
Social media influencer and actor Apoorva Mukhija, known as the Rebel Kid, recently expressed gratitude for the 'India's Got Latent' controversy. She admitted that even though it wasn't easy to get back, she learnt that "the internet is not your reality."Mukhija, in an interview with Zoom, mentioned that it took a lot of courage to get back after the post-'Latent' backlash. She said, "I am really happy that it happened to me. I am grateful that it happened to me because I realised the internet is not your reality. It is a digital world; you don't live there."advertisementThe influencer further said, "These people don't matter; nothing matters. Whatever you think of yourself matters. It took me so much courage to get back out there. I am glad it happened because it helped me detach from what people are saying about me." "I was in the loop of constantly checking Reddit comments, what people are saying, and the roast videos they're making on me. Now, I don't care. I am glad it happened to me kyunki kisi aur ke saath hota toh nahi seh pate (had it happened with someone else, they wouldn't have been able to tolerate it). So, I really killed with that," she among other content creators, faced backlash for her participation on Samay Raina's show 'India's Got Latent'. In February 2025, the show was embroiled in a major controversy after YouTuber Ranveer Allahbadia made a crude joke about parental the same show, Mukhija responded to a contestant. She was criticised for her vulgar remarks druring the complaints were filed in Mumbai seeking action against Allahbadia, Raina and Mukhija, since the latter was one of the guests on 'India's Got Latent'.The National Commission for Women also took serious note of the distasteful comments and summoned them. Mukhija had earlier said that she was forced to vacate her Mumbai home after the was recently seen in the Prime Video reality series 'The Traitors'. She also had a brief role in Ibrahim Ali Khan-Khushi Kapoor's Netflix film 'Nadaaniyan'.- EndsMust Watch
Time of India
23-06-2025
- Entertainment
- Time of India
Samay Raina's India's Got Latent returns to YouTube; Months after controversy: Fans call it 'Best comeback ever'
After a turbulent four-month hiatus, comedian Samay Raina's popular YouTube talent show India's Got Latent has quietly staged a digital comeback—this time through a new clips channel. The return comes months after a major controversy involving fellow YouTuber Ranveer Allahbadia forced the original channel to pull down all content and sparked legal action. The Controversy that took the show offline Earlier in 2025, India's Got Latent found itself at the center of a public and legal firestorm after Ranveer Allahbadia allegedly made an inappropriate comment to a contestant. The backlash was swift and severe and the FIRs were reportedly filed not only against Ranveer but also co-panelists Samay Raina, Apoorva Mukhija, and Ashish Chanchlani . The fallout prompted Samay to take down all episodes from his official channel. He further released a statement expressing emotional exhaustion and regret. 'Everything that is happening has been too much for me to handle,' he wrote. 'My only objective was to make people laugh and have a good time.' A Quiet Comeback With Loyal Support Now, the show's revival on a separate platform—India's Got Latent Clips—has taken the internet by surprise. Including public and previously members-only content, over 500 videos are reuploaded. Fans are celebrating the return. The comment sections are overflowing with enthusiasm, with messages like 'Finallyyyyyyyy… comeback ho hi gaya Latent ka' and 'Best comeback everrr.' While the revival lacks the pomp of a full-scale relaunch, it indicates that the show's core community has remained firmly in place. What's Next for Samay Raina? Even as India's Got Latent finds its way back into the YouTube algorithm, host Samay Raina is far from idle. The comedian is currently on an international stand-up tour that spans Europe, the UK, Australia, and New Zealand. The tour kicked off on June 5 and will wrap up in Sydney on July 20. Samay Raina Speaks Out, DELETES All India's Got Latent Videos From YouTube: 'Too Much To Handle'
News18
22-06-2025
- Entertainment
- News18
Samay Raina's India's Got Latent Makes Comeback On YouTube After Ranveer Allahbadia Controversy
Samay Raina's India's Got Latent returns to YouTube months after controversy involving Ranveer Allahbadia. Fans hail it as the 'best comeback ever.' Four months after being embroiled in a major controversy, India's Got Latent — the YouTube talent show hosted by comedian Samay Raina — has quietly made a return, albeit on a different channel. The show was pulled down earlier this year after YouTuber Ranveer Allahbadia faced widespread backlash for making an inappropriate comment to a contestant involving their parents. The controversial remark led to public outrage and legal repercussions, with multiple FIRs filed against Ranveer, Samay, Apoorva Mukhija, and Ashish Chanchlani. Following the incident, Samay Raina took down all episodes from his official channel and issued a public statement expressing his distress. 'Everything that is happening has been too much for me to handle. I have removed all India's Got Latent videos from my channel. My only objective was to make people laugh and have a good time," he wrote. He also confirmed his full cooperation with authorities investigating the matter. Now, months later, the show's segments have reappeared online — not on the original channel but on a newly active page titled India's Got Latent Clips. The revived clips include content from public and members-only episodes, with over 500 videos currently available for viewing. Fans of the show have welcomed its digital return with open arms. Comments like '2025 is the year of comeback," 'Best comeback everrr," and 'Finallyyyyyyyy… comeback ho hi gaya Latent ka" have flooded the clips, suggesting that the core audience has remained loyal despite the controversy. Meanwhile, Samay Raina is currently touring internationally, performing across Europe, the UK, Australia, and New Zealand. His tour, which began on June 5, will conclude in Sydney on July 20. Whether this quiet return marks a full revival for the show or merely serves as a nostalgic archive remains to be seen — but for now, India's Got Latent seems to be back in the algorithm. First Published:
