Latest news with #Melanotan
New Indian Express
20-07-2025
- Health
- New Indian Express
Medical truth needs to expose cosmetic fiction
At the heart of this trend is a generation growing up on internet advice and reel-life illusions, as well as assured beauty shortcuts to social acceptance and success. However, beneath the promises lies a menacing truth. A recent study revealed that formaldehyde, commonly used in embalming and industrial manufacturing, is also heavily used in cosmetics, face creams, and body lotions for darker skin. Darker-skinned consumers are disproportionately exposed to these toxins. Societal pressures make them consume more beauty products that may contain hazardous chemicals, such as parabens, sulfates, and phthalates. At least 30 percent of users have reported adverse reactions. The film industry plays its own role, celebrating the likes of Shah Rukh Khan and Tom Cruise for their youthfulness and setting unattainable vanity goals. The fallout is becoming apparent as dermatologists report an increasing number of cases of skin damage, infections, vitamin overdose, hormonal and reproductive complications, and a disturbing rise in mental health issues linked to the misuse of steroid creams. The medical fraternity attributes this to the influence of social media and inadequate medical monitoring and prescription practices. Consumers fail to realise that these quick fixes, while enhancing beauty, have multiple side effects. Melanotan nasal sprays often lead to melanoma, and self-injecting Botox filler kits can cause infections and even blindness. It is high time that public discourse caught up with medical reality. Regulation of risky products and their marketing is necessary. Beauty norms should be challenged in visual and broadcast messaging and societal trends. Brands have to be accountable for the safety of their products as well as the narratives they create. Ethical guidelines must be drawn up for influencers to follow.
Roya News
17-07-2025
- Health
- Roya News
Melanotan 1 peptide: Exploring its potential in scientific research
Melanotan 1 peptide has become an intriguing subject of scientific investigation due to its complex interactions within a research model. As a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH), the peptide may exhibit a variety of physiological supports, sparking interest in its possible implications across multiple research fields. Investigations suggest that its engagement with melanocortin receptors may offer valuable insights into processes beyond pigmentation, leading researchers to explore its theoretical support in neurobiology, metabolic regulation, and immunological modulation. This article examines these speculative implications, discussing current research directions while acknowledging the need for further inquiry. Chemical Composition and Mechanism of Action Melanotan 1 is a linear, synthetic peptide composed of 13 amino acids designed to mimic the natural activity of α-MSH. It has been hypothesized that the peptide primarily interacts with melanocortin receptor 1 (MC1R), a key regulator of melanin synthesis. However, studies suggest that the peptide might also engage with other melanocortin receptor subtypes, such as MC3R and MC4R, which are involved in various biological functions related to neural signaling and metabolic processes. The potential binding affinities of Melanotan 1 across these receptors have led to speculation regarding its broader support within a research model. Researchers have theorized that its presence may contribute to a cascade of molecular interactions that may support cellular activity. Investigations suggest that these receptor interactions may be linked to melanogenesis, inflammatory modulation, and cognitive function, providing a foundation for further scientific inquiry. Possible Implications in Dermatological Research Melanin plays a critical role in pigmentation and photoprotection, and research indicates that Melanotan 1 might hold promise in dermatological studies centered on pigment-related conditions. Studies suggest that the peptide may be examined for its theoretical support in disorders such as vitiligo, where melanocyte function is impaired. Some researchers have hypothesized that Melanotan 1 may be studied as part of investigations into potential approaches designed to restore melanin synthesis in impacted areas. Additionally, its interaction with MC1R has led to speculation about its potential support for photoprotection. Melanin is known to absorb ultraviolet radiation, minimizing cellular damage. Investigations suggest that Melanotan 1 may be studied in the context of photoprotective strategies, where researchers aim to understand its potential role in mitigating radiation-induced molecular alterations in skin cells. While definitive findings remain limited, ongoing explorations seek to expand knowledge of melanocortin-associated pathways within dermatological research. Neurobiological Considerations and Cognitive Research Beyond its potential role in pigmentation, Melanotan 1 has been hypothesized to exhibit neurobiological supports, prompting researchers to explore its engagement with the central nervous system. Studies suggest that melanocortin receptors are present in neural tissue and may play a role in cognition, mood regulation, and neuroprotection. Investigations purport that Melanotan 1 might be explored within research domains related to neurodegenerative conditions, including Alzheimer's disease and Parkinson's disease. The melanocortin system has been linked to neuroinflammation and synaptic plasticity, leading scientists to theorize that Melanotan 1 may interact with pathways involved in maintaining neural homeostasis. Some exploratory studies indicate that melanocortin peptides might support neurotransmitter release and receptor sensitivity, potentially contributing to the modulation of neurochemical balance. Research suggests that understanding these interactions may lead to new avenues for investigating neurological disorders and their underlying molecular mechanisms. Furthermore, cognitive science has become a domain of interest regarding Melanotan 1. Researchers have hypothesized that melanocortin signaling might be associated with learning and memory processes, particularly in brain regions involved in synaptic reinforcement. While investigations remain speculative, some studies suggest that Melanotan 1 may be examined for its theoretical role in cognitive function assessments. Metabolic Research and Energy Homeostasis Another potential inquiry regarding Melanotan 1 is its theoretical involvement in metabolic regulation. Research suggests that melanocortin receptors, specifically MC3R and MC4R, play a crucial role in regulating energy balance and modulating hunger hormones. Investigations purport that the peptide might support pathways associated with metabolic homeostasis, including lipid metabolism and glucose regulation. Scientists have theorized that melanocortin peptides may interact with hypothalamic signaling systems, which are crucial for hunger regulation and energy expenditure. Some studies suggest that Melanotan 1 might be explored for its possible implications in metabolic disorders, including obesity and insulin resistance. While definitive mechanisms remain uncertain, research suggests that the peptide's interaction with melanocortin receptors may be examined for its potential role in maintaining metabolic equilibrium. Speculative Immunological Implications Recent investigations have explored the hypothesis that melanocortin peptides may exhibit immunomodulatory properties. Studies suggest that MC1R expression extends beyond melanocytes, potentially supporting immune cell activity. Researchers have theorized that Melanotan 1 may play a role in modulating inflammatory responses, leading to speculation about its potential involvement in immune-related investigations. Some studies suggest that melanocortin receptors may be involved in autoimmune disease mechanisms, prompting researchers to investigate whether Melanotan 1 might be examined in the context of immune signaling pathways. While theoretical considerations remain under review, the intersection of melanocortin activity and immunological response remains an area of interest. Future Research Directions and Considerations As scientific investigations into Melanotan 1 progress, researchers acknowledge the necessity of scrutiny in experimental implications. Studies suggest that further molecular characterization is required to elucidate the peptide's precise support within a research model. Investigations purport that additional research may provide greater insights into its interactions at the cellular level, potentially paving the way for future advancements in peptide-based studies. Evaluations remain crucial in determining the scope of experimental inquiry surrounding synthetic peptides. Researchers emphasize the importance of comprehensive analysis in assessing theoretical implications across diverse biological systems. Investigations suggest that Melanotan 1 may be a valuable target for further exploration, particularly in its interactions with melanocortin-associated pathways. Conclusion Studies have suggested that Melanotan 1 peptide may present a captivating research subject with potential implications spanning dermatology, neurobiology, metabolism, and immunology. While investigations suggest intriguing possibilities, definitive conclusions remain speculative. Scientists have speculated that continued exploration may provide deeper insights into its molecular properties, thereby fostering a more comprehensive understanding of melanocortin receptor interactions within various scientific domains. Researchers interested in further studying the potential of this research compound are encouraged to visit for the most useful peptide data and the highest-quality, most affordable research compounds available online.
Yahoo
25-06-2025
- Health
- Yahoo
Police seize €57 million in illegal Ozempic, peptides, and other black market drugs in global bust
Police agencies worldwide seized $65 million (€57.2 million) worth of counterfeit or unapproved medicines in a major international bust that took aim at the deluge of cheap fakes sold online. Between December and May, authorities in 90 countries – including 16 in the European Union – confiscated 50.4 million doses of drugs that were either fake, misbranded, unapproved, or diverted, according to the International Criminal Police Organization (Interpol), which coordinated the operation. In Europe, many of the seizures were for counterfeit or unapproved weight loss drugs and peptide supplements, which Interpol said reflects the surging popularity of 'cosmetic and performance-enhancing' pharmaceuticals. These drugs are so widely available online and on social media that police are having a hard time keeping up, Alfonso Mejuto Rodríguez, Interpol's pro tempore assistant director of criminal networks, told Euronews Health. Related Rising deaths, fake pills, gang violence: How the EU is struggling to cope with illegal drug problem 'It's not even necessary to go to the dark web [because] there are a lot of advertisements online,' Rodríguez said. The drugs are marketed as 'good for your health, good for your image,' he added. 'That is exactly the risk for human health, because when you buy them, you are not really sure what they contain'. The World Health Organization (WHO) and European Medicines Agency (EMA) have both warned in recent years that the black market is flourishing for counterfeit semaglutide, which is the active ingredient in blockbuster anti-obesity and diabetes medicines such as Ozempic and Wegovy. Interpol said a single semaglutide pen can sell for hundreds of euros on the black market. Meanwhile, peptide seizures were relatively rare until recently. The agency said the uptick in Europe, North America, and Oceania reflects a rise in demand for supplements such as BPC-157, ipamorelin, and melanotan, which are unproven products sold illegally as wellness, anti-ageing, or cosmetic aids. Related Weight loss drugs: New study sheds light on illegal online pharmacies selling Wegovy and Ozempic Melanotan, for example, is a synthetic hormone designed to boost melanin production, giving people the appearance of tanned skin. Sometimes called the 'Barbie drug,' melanotan has taken off on platforms such as TikTok – but it is not regulated in Europe and health agencies have warned that it may cause serious health problems. 'With a lot of substances, the marketing is amplified by influencers, for instance in terms of health and culture,' Rodríguez said. Worldwide, the most commonly seized illicit pharmaceuticals were psychostimulants, anti-anxiety drugs, and Parkinson's disease medicines, followed by erectile dysfunction drugs, Interpol said. Other commonly seized counterfeit or otherwise illegal drugs include anabolic steroids, anti-smoking medicines, dermatological agents, health supplements, herbal products, and psychotropic medications for mental health conditions. Police also confiscated the opioid painkiller oxycodone in Bulgaria, France, Ireland, and Sweden. Related Fake painkillers are circulating in the Netherlands, authorities warn after man dies The sale of counterfeit medicines can have deadly consequences. In March, a 30-year-old man died after taking fake painkillers in the Netherlands, and last month, health authorities in Denmark warned that they were also circulating there. 'It seems that in the West, the demand for painkillers is rising… and criminals are taking advantage of it,' Rodríguez said. As part of the Interpol operation, nearly 800 suspects were arrested and 123 criminal groups were dismantled. Police also took down about 13,000 websites, social media accounts, and bots that advertised and sold illegal or counterfeit medicines online. Authorities in Ireland shuttered about 1,400 online listings for fake or illegal medicines, more than any other country except for Malaysia and Russia. Together with Singapore and Iran, the five countries accounted for 96 per cent of all listings that were taken down. Related Over 230 arrested as Europol dismantles four major drug smuggling networks Ireland also saw large seizures of illegal medicines, as did the Netherlands, Portugal, Spain, Sweden, and the United Kingdom, according to Interpol. In Portugal, for example, police discovered anabolic steroids in eight prisons, which Interpol said was evidence of a criminal smuggling network. The agency noted that Europe-based criminals have easy access to the raw materials and infrastructure needed to run counterfeit drug production networks, meaning they can quickly adapt to changing trends and demand from consumers. 'It's a challenge for law enforcement agencies to follow this activity,' Rodríguez said.
Euronews
25-06-2025
- Health
- Euronews
Police seize €57 million in black market medicines, weight loss drugs
Police agencies worldwide seized $65 million (€57.2 million) worth of counterfeit or unapproved medicines in a major international bust that took aim at the deluge of cheap fakes sold online. Between December and May, authorities in 90 countries – including 16 in the European Union – confiscated 50.4 million doses of drugs that were either fake, misbranded, unapproved, or diverted, according to the International Criminal Police Organization (Interpol), which coordinated the operation. In Europe, many of the seizures were for counterfeit or unapproved weight loss drugs and peptide supplements, which Interpol said reflects the surging popularity of 'cosmetic and performance-enhancing' pharmaceuticals. These drugs are so widely available online and on social media that police are having a hard time keeping up, Alfonso Mejuto Rodríguez, Interpol's pro tempore assistant director of criminal networks, told Euronews Health. 'It's not even necessary to go to the dark web [because] there are a lot of advertisements online,' Rodríguez said. The drugs are marketed as 'good for your health, good for your image,' he added. 'That is exactly the risk for human health, because when you buy them, you are not really sure what they contain'. The World Health Organization (WHO) and European Medicines Agency (EMA) have both warned in recent years that the black market is flourishing for counterfeit semaglutide, which is the active ingredient in blockbuster anti-obesity and diabetes medicines such as Ozempic and Wegovy. Interpol said a single semaglutide pen can sell for hundreds of euros on the black market. Meanwhile, peptide seizures were relatively rare until recently. The agency said the uptick in Europe, North America, and Oceania reflects a rise in demand for supplements such as BPC-157, ipamorelin, and melanotan, which are unproven products sold illegally as wellness, anti-ageing, or cosmetic aids. Melanotan, for example, is a synthetic hormone designed to boost melanin production, giving people the appearance of tanned skin. Sometimes called the 'Barbie drug,' melanotan has taken off on platforms such as TikTok – but it is not regulated in Europe and health agencies have warned that it may cause serious health problems. 'With a lot of substances, the marketing is amplified by influencers, for instance in terms of health and culture,' Rodríguez said. Most commonly seized drugs Worldwide, the most commonly seized illicit pharmaceuticals were psychostimulants, anti-anxiety drugs, and Parkinson's disease medicines, followed by erectile dysfunction drugs, Interpol said. Other commonly seized counterfeit or otherwise illegal drugs include anabolic steroids, anti-smoking medicines, dermatological agents, health supplements, herbal products, and psychotropic medications for mental health conditions. Police also confiscated the opioid painkiller oxycodone in Bulgaria, France, Ireland, and Sweden. The sale of counterfeit medicines can have deadly consequences. In March, a 30-year-old man died after taking fake painkillers in the Netherlands, and last month, health authorities in Denmark warned that they were also circulating there. 'It seems that in the West, the demand for painkillers is rising… and criminals are taking advantage of it,' Rodríguez said. 13,000 websites, accounts shut down As part of the Interpol operation, nearly 800 suspects were arrested and 123 criminal groups were dismantled. Police also took down about 13,000 websites, social media accounts, and bots that advertised and sold illegal or counterfeit medicines online. Authorities in Ireland shuttered about 1,400 online listings for fake or illegal medicines, more than any other country except for Malaysia and Russia. Together with Singapore and Iran, the five countries accounted for 96 per cent of all listings that were taken down. Ireland also saw large seizures of illegal medicines, as did the Netherlands, Portugal, Spain, Sweden, and the United Kingdom, according to Interpol. In Portugal, for example, police discovered anabolic steroids in eight prisons, which Interpol said was evidence of a criminal smuggling network. The agency noted that Europe-based criminals have easy access to the raw materials and infrastructure needed to run counterfeit drug production networks, meaning they can quickly adapt to changing trends and demand from consumers. 'It's a challenge for law enforcement agencies to follow this activity,' Rodríguez said.
Daily Record
16-05-2025
- Health
- Daily Record
Warning over 'dangerous' nasal tanning sprays sold on social media - what are the risks?
One woman was in hospital "unable to breathe" after suffering a severe reaction to an unlicensed nasal tanning spray she bought online Dangerous and unregulated nasal tanning sprays that have a potential link to the skin cancer melanoma are being widely sold across social media platforms, Trading Standards has warned. Scottish people sometimes go to extremes to get a tan. Whether it's sunbathing for too long on holiday, or ignoring health advice and using sunbeds, some will go to great lengths for a boost in complexion. Scots commonly exhibit pale skin, partly due to their Celtic heritage and partly due to Scotland's northern latitude, which leads to less exposure to sunlight. Some may have darker skin or be able to tan to a greater extent, depending on their genetic makeup. But now a new product is being sold on social media that a darker hue to the skin - but come with great risks. These nasal sprays can cause nausea, vomiting, high blood pressure and even changes in mole shape and size, the Chartered Trading Standards Institute (CTSI) said. Nasal tanning sprays are designed to be sprayed into the nostrils and claim to work by administering a substance known as Melanotan 2, a chemical that darkens skin pigmentation. It is illegal to sell medicinal products containing Melanotan 2 in the UK, but as the tanners are sold cosmetically they fall outside that remit. However, they are not covered by UK cosmetics regulations, meaning they are not subjected to the same scrutiny as other over-the-counter beauty products. What are dangers of tanning nasal sprays? Studies had shown a potential link to melanoma, a type of skin cancer, the CTSI warned. Inhaling sprays can irritate the respiratory tract, with potential symptoms such as coughing, sneezing and nasal congestion, and repeated exposure can lead to chronic respiratory issues. One woman, Edith Eagle, told the CTSI that she was in hospital "unable to breathe" after suffering a severe reaction to an unlicensed nasal tanning spray she bought online. When explaining her symptoms, Ms Eagle said: 'I can't even explain it, but I was suffocating inside. "It was as if I was drowning within my own body." The long-term health impacts of using the sprays are not yet known. However, Cleveland Clinic identified some immediate and scary risks including: acne decreased appetite gastrointestinal issues, including diarrhoea and vomiting nausea facial flushing (redness) "Melanotan nasal sprays and injections are not safe to use," Cancer Research UK stated. "Melanotan products have not been tested for safety, quality or effectiveness. "So it is not known if using them causes side effects and how serious they are. "Also, Melanotan products could have harmful chemicals in them that aren't listed on the label. "If you have used Melanotan, you should stop. "Talk to your GP if you have shared needles with someone or if you have any concerns about side effects." What are the warnings? The public has been urged to avoid any type of tanning products that are ingested or inhaled. Instead, safer options such as creams and sprays bought from reputable retailers should be used. Join the Daily Record WhatsApp community! Get the latest news sent straight to your messages by joining our WhatsApp community today. You'll receive daily updates on breaking news as well as the top headlines across Scotland. No one will be able to see who is signed up and no one can send messages except the Daily Record team. All you have to do is click here if you're on mobile, select 'Join Community' and you're in! If you're on a desktop, simply scan the QR code above with your phone and click 'Join Community'. We also treat our community members to special offers, promotions, and adverts from us and our partners. If you don't like our community, you can check out any time you like. To leave our community click on the name at the top of your screen and choose 'exit group'. If you're curious, you can read our Privacy Notice. "Edith's story is a sobering one, and an example of what can happen when putting unregulated products into our bodies," Richard Knight, CTSI lead officer for cosmetics and beauty, said. "Unlike cosmetic products, nasal tanning sprays are unlikely to have had expert safety assessment, and use of relevant health warnings and instructions for safe use are rare. "This means that no-one, including influencers, can truly know the risks of using these quasi-medical potions."
