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Acesis Biomed Secures Patents Advancing Testosterone-Inducing Drug Development
Acesis Biomed Secures Patents Advancing Testosterone-Inducing Drug Development

Business Upturn

time30-06-2025

  • Health
  • Business Upturn

Acesis Biomed Secures Patents Advancing Testosterone-Inducing Drug Development

Centennial, Colorado, June 30, 2025 (GLOBE NEWSWIRE) — Acesis Holdings Corporation ('Acesis Biomed'), a pre-clinical stage biomedical company pioneering oral treatments for metabolic and endocrine disorders linked to low testosterone, today announced a meaningful expansion of its intellectual property portfolio with the granting of two patents supporting the development of its novel treatment for low testosterone. The United States Patent and Trademark Office has issued U.S. Patent No. 12324839, effective June 10, 2025, with a notable 380-day term extension. Additionally, Chinese Patent No. ZL2019800872788 was granted on June 6, 2025, strengthening Acesis's global presence and international protection for its novel drug candidates. The milestone coincides with Men's Health Month, underscoring the company's focus on advancing solutions for hormone-related health conditions. Testosterone deficiency, or low T, affects millions of men globally and is increasingly recognized not only for its impact on energy and libido, but also for its role in serious chronic conditions such as obesity, type 2 diabetes, cardiovascular disease, and diminished quality of life. Despite its prevalence, current treatments often rely on hormone replacement therapies, which may not be suitable for all patients and can carry risks such as infertility. Acesis Biomed is developing a potentially first-in-class platform of oral, mechanism-based treatment designed to stimulate the body's own production of natural testosterone. This approach is designed to address a critical unmet need by potentially offering an alternative to traditional therapies. 'This patent milestone highlights our continued progress and commitment to scientific innovation and strengthens the value of our emerging therapeutic pipeline,' said Costas Karatzas, PhD, Co-founder and CEO of Acesis Biomed. 'Testosterone deficiency remains widely underdiagnosed and an undertreated condition in men. Furthermore, this achievement, especially during Men's Health Month, reaffirms our mission to provide safe, effective novel treatments that improve health outcomes for men worldwide with low T.' With a growing awareness of the risks associated with untreated low T, Acesis Biomed offers both patients and investors a compelling opportunity at the forefront of men's health innovation. Acesis is currently raising capital through a Regulation CF Crowdfunding (RegCF) campaign to support the advancement of its proprietary oral drug candidates. For more details and to join the campaign, visit: About Acesis Biomed Acesis Holdings Corporation ('Acesis Biomed' or the 'Company') is a pre-clinical biomedical company developing a pipeline of oral drug candidates targeting metabolic and endocrine disorders associated with testosterone deficiency (low T). With an initial focus on male hypogonadism, Acesis is committed to improving outcomes across multiple co-morbidities of low-T, including type 2 diabetes, obesity, and non-alcoholic fatty liver disease. Find out more at Disclaimer: The above press release comes to you under an arrangement with GlobeNewswire. Business Upturn takes no editorial responsibility for the same. Ahmedabad Plane Crash

Men's Health Month: Why prostate cancer screening is crucial for your health
Men's Health Month: Why prostate cancer screening is crucial for your health

IOL News

time23-06-2025

  • Health
  • IOL News

Men's Health Month: Why prostate cancer screening is crucial for your health

This Men's Health Month, let's challenge ourselves and those around us to prioritise our health. Prostate cancer isn't just a scary headline or another item on a doctor's checklist - it's a very real, very present risk that could impact you or the men you care about. Every year, thousands of South African men are diagnosed, and the reality is stark: one in eight men here will develop prostate cancer in their lifetime. When last did you have an honest conversation about your health? If you're like most South African men, the answer is: not often enough. What should you look for? According to Dr Hannes Brummer and Dr Johan Coetzee, experienced urologists at Netcare Greenacres Hospital, 'Most men don't feel any symptoms until prostate cancer has already progressed. That's why regular screening is so important.' It's easy to put off check-ups, especially when you feel fine. But here's the catch, early-stage prostate cancer almost never shouts for attention. By the time you notice obvious changes, it might already be serious. That's not just a statistic; it's a neighbour, a brother, a father, a friend. To be honest, many of us would rather ignore the quiet warnings our bodies send. But prostate cancer is sneaky - it's called the silent threat for a reason. In South Africa, though, many men only seek help when symptoms are advanced often too late for simple treatments. For most men, early prostate cancer doesn't come with a flashing warning sign. However, changes in urination may indicate other underlying issues Here's what to keep an eye out for, even though these are often caused by less serious issues, like an enlarged prostate (a very common, non-cancerous problem): Difficulty starting or stopping urination A weak urine stream Feeling like your bladder isn't emptying fully Dribbling after urination Needing to go more often, especially at night An urgent need to urinate, sometimes with leaks These symptoms are more often linked to benign conditions, but they're still worth a chat with your GP. The real game changer is early detection. Catching prostate cancer early can save lives. Thanks to advances like the PSA (Prostate Specific Antigen) blood test, available at most South African GPs, early detection is more possible than ever. Coetzee explains, 'The PSA test is a simple blood test that can pick up signs of trouble before symptoms appear. This gives men a much better chance of treating the cancer while it's still highly curable.' Globally, research shows that countries with higher rates of screening have lower death rates from prostate cancer. In South Africa, though, many men only seek help when symptoms are advanced - often too late for simple treatments. When things get serious If prostate cancer grows outside the prostate or spreads to other parts of the body, the symptoms can become more obvious and serious. These can include: Persistent back, hip or pelvic pain Blood in urine or semen Problems getting or keeping an erection Unexplained weight loss. It's critical to know that these symptoms can also be caused by other health issues, but ignoring them is never the answer. There's a stigma Many of us grew up believing men should just "tough it out" and not talk about personal health. But what's tougher: facing a quick, routine check-up or battling a disease that could have been prevented? Brummer puts it simply: 'Making the time now and every year could help save your life.' This Men's Health Month, let's challenge ourselves and those around us to prioritise our health. Book that screening. Start the conversation. Ask questions. It's not just about you; it's about being there for your family, your community, your future.

Ignoring the warning signs: Men's health risks you shouldn't overlook
Ignoring the warning signs: Men's health risks you shouldn't overlook

The Citizen

time22-06-2025

  • Health
  • The Citizen

Ignoring the warning signs: Men's health risks you shouldn't overlook

June is recognised as Men's Health Month, yet many South African men still avoid visiting healthcare facilities. Professional nurse Nhlanhla Mofokeng spoke to the Brakpan Herald about the reasons why so many men delay seeking medical attention or avoid regular health screenings. Mofokeng cited a combination of social, psychological, and systemic factors—including societal norms around masculinity, perceived inconvenience, denial and fear, unfamiliarity with the health system, lack of awareness, and broader cultural and socioeconomic challenges. 'Many men ignore or delay treatment for health issues until the condition has advanced,' she said. 'In my unit alone, we see numerous cases of young men who have attempted to take their own lives.' Changing this pattern, Mofokeng said, requires breaking through cultural, emotional, and systemic barriers. Strategies include changing the narrative around masculinity, involving loved ones in healthcare decisions, making clinics more accessible and less intimidating, using relatable male role models, and empowering male healthcare workers to lead by example. 'I believe recognising warning signs early is one of the best ways to prevent serious illness or death,' she said. 'Many men downplay symptoms, but certain red flags should never be ignored—regardless of age or lifestyle.' Mofokeng listed the following symptoms men should take seriously: • Chest pain or discomfort • Shortness of breath • Sudden confusion, difficulty speaking, or facial drooping • Unexplained weight loss • Constant fatigue • Changes in bowel or bladder habits • Erectile dysfunction • Lumps or swelling in the testicles • Persistent cough or hoarseness • Mood changes or withdrawal She also emphasised the severity of South Africa's TB crisis. 'Unexplained weight loss, coughing for more than two weeks, night sweats, and loss of appetite could be signs of TB. Clinics offer TB testing and treatment, but men often don't know these services exist,' she said. Mofokeng stressed that many men are unaware of the wide range of services available at public health facilities, contributing to low utilisation. 'Men can access general medical services, male-specific health checks, cancer screenings, mental health support, sexual and reproductive healthcare, diagnostic tests, preventative care, and emergency services,' she explained. She also highlighted several commonly overlooked or ignored health concerns among men: Commonly overlooked men's health issues: • Cardiovascular disease: Men often dismiss chest pain or shortness of breath. High blood pressure—known as the 'silent killer'—is frequently undiagnosed. • Mental health issues: Depression, anxiety, and stress are heavily stigmatised. Men may express emotional distress through anger, substance use, or withdrawal. Suicide rates are notably high among older and middle-aged men. • Diabetes: Symptoms such as fatigue, frequent urination, and slow-healing wounds are often attributed to aging. Type 2 diabetes can go undiagnosed for years without regular screening. • Obesity and poor nutrition: Many men overlook gradual weight gain and poor dietary habits. Obesity increases the risk of heart disease, diabetes, and cancer. • Prostate issues: Urinary problems like frequent urination or weak flow are often ignored. Conditions such as prostate cancer and BPH are common, yet screenings are neglected. • Testicular issues: Testicular cancer mainly affects younger men, but self-exams are rare. Many avoid discussing lumps or swelling due to embarrassment. • Erectile dysfunction: ED is often seen as a threat to masculinity, but it can be a warning sign of heart disease, diabetes, or hormonal issues. • Substance abuse: Men are more likely to engage in high-risk alcohol or drug use and less likely to seek help. These behaviours are often coping mechanisms. • Colon cancer: Fear or embarrassment about colonoscopies prevents many from getting screened. Yet colon cancer is highly treatable if caught early. • Injuries and risky behaviour: Younger men, in particular, are more prone to reckless behaviour and often ignore injuries that may lead to chronic health problems. 'Improving men's health starts with awareness and support. If we can create safe spaces for men to speak, get informed, and seek help without shame, we can save lives,' Mofokeng concluded. At Caxton, we employ humans to generate daily fresh news, not AI intervention. Happy reading!

Man rescued from Grey Avenue bridge in dramatic N3 incident in Ekurhuleni
Man rescued from Grey Avenue bridge in dramatic N3 incident in Ekurhuleni

The Citizen

time21-06-2025

  • Health
  • The Citizen

Man rescued from Grey Avenue bridge in dramatic N3 incident in Ekurhuleni

A dramatic incident brought traffic to a standstill on the N3 after a man threatened to jump from the Grey Avenue bridge into oncoming traffic on Wednesday. Alberton Record reports that shortly before 17:00, motorists reported seeing an individual perched on the edge of the bridge, poised to hurl himself into the fast-moving N3 lanes. Traffic police immediately halted vehicle flow and diverted motorists to alternative routes. The disruption left commuters stranded for hours as authorities worked to secure the scene. Emergency responders, including negotiators and mental health-trained paramedics, quickly attended and initiated a sensitive and professional negotiation process. After several tense minutes, they successfully convinced the man to step back and escorted him to safety. Community and expert reaction Alberton Record spoke to Dr Frans Korb, psychiatrist, clinical psychologist and South African Depression and Anxiety Group (SADAG) board member, about the critical importance of recognising and addressing suicidal thoughts, especially among men, while aligning his insights with SADAG's mission and June's designation as Men's Health Month. Korb emphasised that when suicidal ideation emerges, no matter how justified or overwhelming one's situation feels, seeking professional support promptly can be life-saving. He explained that men often interpret these thoughts as a personal failure or weakness, but intervention can halt escalation and open pathways to recovery. 'Stigma is the principal obstacle. Men are taught to be the strongest, to never show vulnerability. This societal expectation frequently leads to denial and isolation. Other factors include fear of being perceived as weak, lack of awareness about mental health resources, and difficulties navigating the support system,' Korb said. He urged normalising mental health conversations and increasing visibility of male-friendly support channels, such as SADAG's helplines and support groups. Campaigns highlighting role models who have sought help can also dismantle harmful stereotypes. Immediate steps in acute crises When a loved one or bystander confronts someone in crisis, Dr Korb recommends: Approaching calmly and avoiding confrontation Listening empathetically, acknowledging their pain without judgement Reassuring them that help is available and staying with them until professionals arrive Contacting emergency services immediately After the acute incident, encourage them to connect with support services like SADAG. SADAG's role and ethical mission SADAG's vision is a South Africa where mental illness is acknowledged and accessible help is available when needed. Its services include: Running 24/7 helplines (SMS: 31393, WhatsApp: 087 163 2030) Facilitating over 170 free support groups, including specialised male-only spaces to encourage openness and healing Developing stigma-busting campaigns and community outreach to normalise help-seeking behaviour During June's focus on men's health, SADAG advocates targeted messaging underscoring that asking for help is not weakness but courage. The bigger picture: Statistics and stigma South Africa ranks 10th globally for suicide rates, with men being five times more likely to die by suicide than women. Korb emphasised that stigma is the silent killer. 'What kills most men is the stigma that they should always be the strongest,' he said. Breaking this narrative and encouraging empathy can reduce barriers to help-seeking. Tips for those having suicidal thoughts Reach out immediately to a friend, counsellor or helpline, no matter how small the risk feels. Remind yourself that thoughts are not facts; help is real and effective. Understand that vulnerability is human, not shameful. Keep helpline numbers where you can see them, including SADAG's Lifeline or your family doctor. If you or someone you know is in crisis, contact: 24/7 Suicide Crisis Line: 080 056 7567 SADAG SMS Helpline: 31393 WhatsApp: 087 163 2030 'Your life matters. Please talk,' Korb concluded. Breaking news at your fingertips… Follow Caxton Network News on Facebook and join our WhatsApp channel. Nuus wat saakmaak. Volg Caxton Netwerk-nuus op Facebook en sluit aan by ons WhatsApp-kanaal. Read original story on At Caxton, we employ humans to generate daily fresh news, not AI intervention. Happy reading!

NYSE Content Advisory: Pre-Market update + Wall Street reopens after Juneteenth
NYSE Content Advisory: Pre-Market update + Wall Street reopens after Juneteenth

Malaysian Reserve

time20-06-2025

  • Business
  • Malaysian Reserve

NYSE Content Advisory: Pre-Market update + Wall Street reopens after Juneteenth

NEW YORK, June 20, 2025 /CNW/ — The New York Stock Exchange (NYSE) provides a daily pre-market update directly from the NYSE Trading Floor. Access today's NYSE Pre-market update for market insights before trading begins. Kristen Scholer delivers the pre-market update on June 20th Traders return to Wall Street this morning following the Juneteenth Holiday for the final day of trading this week. Stocks are down fractionally early Friday and are little changed on the week. Equities had a mixed session Wednesday after the Federal Reserve kept interest rates unchanged. Following the decision, Fed Chair Powell said the central bank is 'well-positioned to wait' before lowering rates. On Thursday, White House Press Secretary Karoline Leavitt said that President Trump will decide if the U.S. will get involved in the Middle East conflict over the next two weeks. Opening BellZERO Prostate Cancer & Novartis (NYSE: NVS) commemorate Men's Health Month Closing BellAmerican Integrity (NYSE: AII) celebrates the launch of its IPO Click here to download the NYSE TV App

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