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Govt warns some heart medicines can cause erectile dysfunction, psoriasis
Govt warns some heart medicines can cause erectile dysfunction, psoriasis

Mint

time04-07-2025

  • Health
  • Mint

Govt warns some heart medicines can cause erectile dysfunction, psoriasis

Indian Pharmacopoeia Commission (IPC) has issued an alert on widely-prescribed beta-blockers (heart medications), saying that these drugs can cause severe adverse reactions, including erectile dysfunction and psoriasis (a chronic skin condition). Beta-blockers, often prescribed by doctors to manage abnormal heart rhythms, prevent heart attacks, and treat migraines, are a cornerstone in cardiovascular care. However, a recent analysis of adverse drug reactions by the IPC revealed that combinations of beta-blockers such as Propranolol and Metoprolol are associated with psoriasis. Furthermore, combinations including Metoprolol, Propranolol, Atenolol, and Carvedilol have been linked to reversible erectile dysfunction. Healthcare professionals, patients/consumers are advised to closely monitor the possibility of the above ADRs associated with the use of above suspected drugs, the IPC said. "If such reactions are encountered, please report to the NCC-PvPI (National Coordination Centre - Pharmacovigilance Programme of India), IPC by filling of Suspected Adverse Drug Reactions Reporting Form/Medicines Side Effect Reporting Form for Consumer," the IPC said in a communication to hospitals and healthcare professionals. Mint has reviewed a copy of the communication. This alert from the IPC, which is an autonomous organisation under the health ministry that sets safety standards for drugs manufactured and sold in the country, follows earlier reports from the government raising alarms about these life-saving drugs. An adverse drug reaction (ADR) is defined as a harmful, unintended result from taking medication, which can occur from a single dose, prolonged use, or drug combinations. Queries sent to the health ministry regarding the alert remained unanswered till press time. India's beta-blocker market is substantial, currently valued at over $11 billion and projected to cross $15 billion by 2030. Given the widespread use of these medications, the IPC has advised healthcare professionals, patients, and consumers to "closely monitor the possibility of the adverse drug reactions associated with the use of suspected beta blockers drugs". The IPC plays a crucial role in monitoring adverse drug reactions across the Indian population, assisting the Central Drugs Standard Control Organization (CDSCO) in making regulatory decisions to ensure safe use of medicines. Since March, the IPC has identified adverse reactions in connection with eight different drugs. Dr. Amit Bhushan Sharma, director & unit head, cardiology, Paras Health, Gurugram, said that the recent alert issued by the Indian Pharmacopoeia Commission regarding adverse drug reactions linked to beta blockers highlight a serious concern. 'While these drugs are effective and often life-saving, their side effects can significantly affect a person's quality of life. Patients experiencing any unusual symptoms should report to their doctors and in most cases doctors can adjust the dosage or recommend alternative treatments. Monitoring, regular follow-ups, and clear communication with healthcare providers are essential to safely managing these medications and minimizing the risk of ADRs.'

Ahead of Finale, Fox's Doc Gave Fans More Reasons to Jeer Dr. Miller
Ahead of Finale, Fox's Doc Gave Fans More Reasons to Jeer Dr. Miller

Yahoo

time12-03-2025

  • Entertainment
  • Yahoo

Ahead of Finale, Fox's Doc Gave Fans More Reasons to Jeer Dr. Miller

The following contains spoilers from the March 11 episode of Fox's . Just when you started warming up to Dr. Richard Miller, understanding as we now do his difficult home life…. Doc went and had him do the unthinkable. And boy, did it have immediate repercussions. More from TVLine Doc Renewed for 22-Episode Season 2 After Emerging as Fox's Most-Watched Entertainment Program Alert: MPU Season 3: The Resident's Malcolm-Jamal Warner Among Cast Additions Is The Masked Singer's Coral a Disney Star in Disguise? Here's Our Theory Arguably the biggest question born of the (already-renewed!) Fox drama's inciting incident had to do with a mistake that Richard made, before colleague Dr. Amy Larsen's (Molly Parker) life-changing car accident, when treating an older patient, 83-year-old Bill Dixon, who had choked on, well, a ham sandwich. Richard accidentally pushed Metoprolol, a beta blocker, into the patient's IV, causing him to code and then die. Amy of course does not remember uncovering Richard's mistake, but her review of email drafts — namely a curious one with only the subject line 'Dixon' — set her on a journey that tagged in Nurse Julie, who in turn was curious to see that Dixon's autopsy report had restricted access. Julie asked Richard about it, and he said/lied that he would circle back with Amy himself. Instead, he made a beeline to his lawyer. 'My negligence killed a man, and then I lied about it,' Richard affirmed to his increasingly anxious lawyer. 'How do you defend that?' Richard's lawyer suggested that maybe perhaps possibly there could be/might be an 'alternate theory' about why Dixon died. Afterwards, we saw Richard privately huddle with Nurse Liz, who was with him when Dixon coded. Amy meanwhile learned of Richard's slipperiness from Julie, then paid a visit to Dr. Franco from pathology, who recalled that Dr. Miller had (atypically) made changes to the deceased's medical file, removing the mention of Metoprolol. When Amy asked Liz for her recollection of the event, the young nurse, fresh from her meeting with Dr. Miller, said that he had taken Amiodarone from her cart and administered it himself. Liz then urged Dr. Larsen to not dig into the matter further. Dig Amy did, though, marching into Richard's office to declare, 'I know what happened to Dixon' — that after the patient aspirated and Richard called a code, he mistakenly administered Metoprolol. The old Amy had figured it out, and 'that is why you were so keen to get rid of me' after the accident, she surmised. Caught dead to rights, Richard somehow had the temerity to 'correct' Amy, saying, 'I didn't kill Bill Dixon; you did,' by going behind his back weeks prior to write Dixon a script for Metoprolol and then fail to add it to the man's chart. 'I haven't been covering my ass, Amy,' he added. 'I've been covering yours.' Amy tried to wave off the accusation, but Richard said that Liz would back him up, because she was there when Amy wrote the prescription. Hit by a ton of bricks by this devastating 'news,' Amy was emotionally vulnerable when she ran into ex-husband Michael in the elevator. Sensing her distress, Michael pulled her into a comforting hug, and a face caress… which turned into a long, passionate, yearning kiss. What did you think of this week's , and what are your predictions for the already-renewed freshman drama's Season 1 finale next week? Did Amy make the right call with TJ's father? Who will learn about Michael and Amy's kiss?Molly Parker Revisits Deadwood, Swingtown, House of Cards, Lost in Space and Other Roles View List Best of TVLine Mrs. Maisel Flash-Forward List: All of Season 5's Futuristic Easter Eggs Yellowjackets Recap: The Morning After Yellowjackets Recap: The First Supper

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