Latest news with #MiNKTherapeutics
Business Insider
15-07-2025
- Business
- Business Insider
Why Is MiNK Therapeutics Stock (INKT) Down 30% Today?
MiNK Therapeutics (INKT) stock plummeted on Monday after the shares underwent a massive rally on Friday alongside positive cancer data. One reason for this drop is the stock adjusting to its new value. Traders likely boosted the stock too high during Friday's rally, and it's settling to a more reasonable price that is still well above its pre-surge value. Elevate Your Investing Strategy: Take advantage of TipRanks Premium at 50% off! Unlock powerful investing tools, advanced data, and expert analyst insights to help you invest with confidence. Make smarter investment decisions with TipRanks' Smart Investor Picks, delivered to your inbox every week. Another factor that could have weighed down INKT stock today is a downgrade from William Blair analyst Matt Phipps. This analyst downgraded MiNK Therapeutics to a Hold from a Buy rating. Additionally, H.C. Wainwright analyst Emily Bodnar reiterated a Buy rating and $35 price target, suggesting a 45.46% downside for the shares. INKT stock was down 28.3% in pre-market trading on Monday, following a 730.14% rally on Friday. The stock was up 820.66% year-to-date and has increased 462.89% over the past 12 months. Trading volume today is muted at roughly 310,000 shares, compared to a three-month daily average of about 1.61 million units. Is MiNK Therapeutics Stock a Buy, Sell, or Hold? Turning to Wall Street, the analysts' consensus rating for MiNK Therapeutics is Moderate Buy, based on one Buy and one Hold rating over the past three months. With that comes an average INKT stock price target of $35, representing a potential 45.46% downside for the shares.
Business Insider
12-07-2025
- Business
- Business Insider
Why Is MiNK Therapeutics Stock (INKT) Up 190% Today?
MiNK Therapeutics (INKT) stock rocketed higher on Friday after the clinical-stage biopharmaceutical company announced the publication of a complete remission in Oncogene. This case saw a patient with metastatic, treatment-refractory testicular cancer undergo a complete, durable remission with the use of agenT-797, the company's allogeneic iNKT cell therapy. Elevate Your Investing Strategy: Take advantage of TipRanks Premium at 50% off! Unlock powerful investing tools, advanced data, and expert analyst insights to help you invest with confidence. Make smarter investment decisions with TipRanks' Smart Investor Picks, delivered to your inbox every week. Investors will note that the patient has been in complete remission for two years with no signs of the cancer returning. Additionally, he underwent several therapies before MiNK Therapeutics' that failed to eliminate the cancer. He reached complete remission after a single treatment with agenT-797 alongside nivolumab. Dr. Benjamin Garmezy, Assistant Director of Genitourinary Research for Sarah Cannon Research Institute at SCRI Oncology Partners, said, 'We observed a remarkable response in a patient who had exhausted standard and experimental treatments, offering compelling evidence to further pursue clinical studies of iNKT cell therapies in solid tumors.' MiNK Therapeutics Stock Movement Today MiNK Therapeutics stock was up 192.63% in pre-market trading on Friday, following a 6.16% rally yesterday. The shares were also up 10.9% year to date, but have fallen 30.98% over the past 12 months. Today's rally came with heavy trading of INKT stock, as some 5 million shares changed hands, compared to a three-month daily average of about 10,930 units. Is MiNK Therapeutics Stock a Buy, Sell, or Hold? Turning to Wall Street, the analysts' consensus rating for MiNK Therapeutics is Moderate Buy, based on two Buy ratings over the past three months. With that comes an average INKT stock price target of $35, representing a potential 352.78% upside for the shares.
Time of India
11-07-2025
- Business
- Time of India
Biotech breakthrough? INKT stock skyrockets 530% after cell therapy cures testicular cancer
MiNK Therapeutics (NASDAQ: INKT) saw its stock price soar by over 530% today—hitting a peak of $65.55 —after the company revealed a potential breakthrough in cancer treatment. What triggered INKT's insane stock rally? MiNK announced that one patient with advanced, treatment-resistant testicular cancer experienced a complete and durable remission after receiving just a single infusion of its experimental off-the-shelf iNKT cell therapy, agenT‑797, alongside nivolumab (an immune checkpoint inhibitor). Even more impressive? That patient has remained completely disease-free for more than two years, according to data just published in the journal Oncogene by Nature . How did the treatment work—and why is it such a big deal? No chemo or radiation was needed—just a single dose of engineered iNKT cells, which are a rare type of immune cell known for attacking both tumors and viruses. The therapy was well-tolerated with no signs of graft-versus-host disease or cytokine storm , common side effects in other cell therapies. These infused donor cells persisted in the patient's body for six months , continuing to fight the cancer. Why is Wall Street going wild? This isn't just another biotech announcement—this is a first-of-its-kind human result. Investors are reacting to the possibility that agenT-797 could be a scalable, off-the-shelf alternative to expensive and complicated CAR-T therapies. And because the treatment worked in a solid tumor (traditionally harder to treat with cell therapies), the implications go far beyond just testicular cancer. How did AgenT-797 help a testicular cancer patient become disease-free? The standout case that grabbed attention involved a testicular cancer patient who had exhausted all available treatments, including both standard and experimental options. After receiving AgenT-797, the patient achieved complete remission, with no signs of the disease returning even after 24 months. Live Events Dr. Benjamin Garmezy, Assistant Director of Genitourinary Research at Sarah Cannon Research Institute, described the result as a breakthrough. "We observed a remarkable response in a patient who had exhausted standard and experimental treatments," Garmezy said, as quoted in Oncogene . He added that the case highlights the "powerful potential of iNKT cells" in tackling aggressive cancers where traditional therapies fall short. What makes MiNK's iNKT platform different from other cancer treatments? MiNK's cell therapy, AgenT-797, is not like the typical personalized cell treatments that need to be customized for each patient. It's an allogeneic, or off-the-shelf product—ready for use without waiting for a patient's cells to be engineered. This iNKT cell platform targets solid tumors in a way that activates both innate and adaptive immunity, making it potentially effective against cancers that have been resistant to traditional therapies and even immunotherapy. The company believes this case sets a precedent that could expand the use of iNKT-based therapies in treating other solid tumors beyond testicular cancer. Is AgenT-797 showing results in other types of cancer too? Yes. Another case report, also published in Oncogene , involved a metastatic gastric cancer patient. After a single infusion of AgenT-797 combined with Opdivo—a widely used cancer immunotherapy from Bristol-Myers Squibb—the patient experienced a 42% tumor reduction and over nine months of progression-free survival. These results support the ongoing Phase II trial of AgenT-797 in second-line gastric cancer, which is actively enrolling participants. The promising early outcomes are likely to boost interest and investment in this trial as it moves forward. What about other cancers? MiNK also released encouraging data from an ongoing Phase 2 gastric cancer trial, where agenT-797 showed: Stronger immune activation, and Improved patient survival rates, even in very aggressive tumor types. Is this too good to be true? As always in biotech, one patient does not make a cure. Despite the euphoria, there are a few things to keep in mind: Pros Cons Potentially revolutionary treatment for solid tumors Still very early-stage: just one case of remission No major side effects like GvHD or cytokine storm Limited data; needs larger clinical trials Off-the-shelf therapy = easier to scale than CAR-T MiNK is a small-cap company with limited cash runway What does MiNK Therapeutics' financial health look like right now? As of March 31, 2025, MiNK reported having $3.2 million in cash on hand. While that's a relatively modest amount for a biotech company in active clinical development, the positive clinical results and surging stock price may open new doors for funding or partnerships in the near future. In the past year, INKT stock has moved in a range between $4.56 and $13.79. But today's pre-market rally to $21 marks a dramatic leap, signaling growing investor confidence in the company's science and potential market opportunity. Why does this matter for the future of cancer immunotherapy? The testicular cancer case treated with AgenT-797 offers real-world proof that iNKT cell therapies might have the power to treat cancers that don't respond to anything else. This could change how certain solid tumors are treated, especially in patients with few remaining options. Testicular cancer, though rare—it affects roughly 1 in 250 males in their lifetime according to the American Cancer Society—can become especially difficult to treat when it spreads or resists standard therapies. If MiNK's approach proves consistently effective, it may redefine what's possible in advanced cancer care. MiNK Therapeutics' iNKT-based AgenT-797 therapy is gaining momentum after helping a testicular cancer patient achieve long-term remission, with stock soaring as investors take notice. With ongoing trials in gastric cancer and solid tumors, and early signs of effectiveness, MiNK is now at the center of conversations around the future of off-the-shelf cell therapies in oncology. What's next for MiNK and agenT-797? MiNK is now focused on: Expanding clinical trials for solid tumors and hematologic cancers Securing more funding and possibly Big Pharma partnerships Advancing agenT-797 toward FDA approval MiNK also recently received NIAID funding to study their iNKT therapy in graft-versus-host disease, opening more doors for future applications. FAQs: Q1. What is MiNK Therapeutics' AgenT-797 used for? AgenT-797 is used to treat advanced cancers like testicular and gastric tumors using iNKT cell therapy. Q2. Why did MiNK Therapeutics stock surge 500%? The stock jumped after a testicular cancer patient fully recovered using MiNK's cell therapy, AgenT-797.
Yahoo
11-07-2025
- Business
- Yahoo
MiNK Therapeutics Announces Publication of Complete Remission Following Allogeneic iNKT Cell Therapy in Metastatic Testicular Cancer
New report adds to growing evidence of iNKT cell therapy's potential in solid tumors NEW YORK, July 11, 2025 (GLOBE NEWSWIRE) -- MiNK Therapeutics, Inc. (NASDAQ: INKT), a clinical-stage biopharmaceutical company pioneering allogeneic, off-the-shelf invariant natural killer T (iNKT) cell therapies, today announced the publication of another landmark case in Nature's Oncogene describing a complete and durable remission in a patient with metastatic, treatment-refractory testicular cancer, following treatment with agenT-797, MiNK's allogeneic iNKT cell therapy. Complete remission after failure on platinum-based chemotherapy, autologous stem cell transplant, and multiple ICIs (anti–PD-1, anti–CTLA-4, and anti–TIGIT) The publication, titled 'Salvage therapy with allogeneic invariant natural killer T cells in a heavily pre-treated germ cell tumor,' presents a patient case from MiNK's clinical trial (NCT05108623). The patient had progressed after multiple lines of therapy—including platinum-based chemotherapy, autologous stem cell transplant, and multiple immune checkpoint inhibitors (anti–PD-1, anti–CTLA-4, and anti–TIGIT)—and received a single infusion of agenT-797 alongside nivolumab. The patient achieved a complete clinical, radiologic, and biochemical remission, with no evidence of disease over two years later. Donor iNKT cells were detectable up to six months post-infusion, and treatment was well-tolerated with no cytokine release syndrome (CRS) or graft-versus-host disease (GVHD). 'This case exemplifies the powerful potential of iNKT cells in treating even the most challenging cancers,' said Dr. Benjamin Garmezy, Assistant Director of Genitourinary Research for Sarah Cannon Research Institute at SCRI Oncology Partners. 'We observed a remarkable response in a patient who had exhausted standard and experimental treatments, offering compelling evidence to further pursue clinical studies of iNKT cell therapies in solid tumors.' Durable Responses & Immune Activation in Solid Tumors with Allo-iNKT Therapy These findings are part of a growing body of clinical evidence supporting the potential of agenT-797 in solid tumors. At the 2025 inaugural AACR Immuno-Oncology meeting, MiNK presented data from its Phase 2 trial in 2L gastric cancer, demonstrating immune activation, increased tumor infiltration, and early signals of tumor control in patients previously refractory to checkpoint inhibitors. Notably, extended survival beyond 12 months was observed in several patients—an outcome rarely seen in this setting. These clinical observations were further reinforced in a separate peer-reviewed case report published in Oncogene, which described a patient with metastatic gastric cancer who achieved a 42% tumor reduction and more than nine months of progression-free survival following a single infusion of agenT-797 in combination with nivolumab. Together, these data highlight the potential of agenT-797 to reshape the tumor microenvironment and deliver durable clinical activity, even in heavily pretreated, immunotherapy-resistant cancers. The ongoing Phase 2 trial in gastric cancer (NCT06251973) is actively enrolling, with additional readouts expected in upcoming months. You can access the full publication here. About MiNK Therapeutics MiNK Therapeutics is a clinical-stage biopharmaceutical company advancing a new class of allogeneic invariant natural killer T (iNKT) cell therapies and precision-targeted immune technologies. MiNK's proprietary platform is designed to restore immune balance and drive cytotoxic responses across cancer, immune-mediated diseases, and pulmonary immune failure. The company's lead candidate, agenT-797, is an off-the-shelf, cryopreserved iNKT cell therapy currently in clinical development for graft-versus-host disease (GvHD), solid tumors, and severe pulmonary inflammation. MiNK is also advancing a pipeline of T cell receptor (TCR)-based therapies and neoantigen discovery tools that enable highly specific immune targeting across tumor and tissue types. With a scalable manufacturing process and a differentiated mechanism that bridges innate and adaptive immunity, MiNK is committed to delivering accessible, durable, and broadly applicable immune reconstitution therapies. For more information, visit or follow us on X @MiNK_iNKT. Information important to investors is routinely posted to our website and social media channels. About AgenT-797 AgenT-797 is an allogeneic invariant natural killer T (iNKT) cell therapy that harnesses the dual power of innate and adaptive immunity. iNKTs function as 'master regulators,' combining the cytotoxic capabilities of NK cells with T-cell–like antigen recognition and memory. This unique biology enables a robust, pathogen-agnostic immune response that can be directed against hard-to-treat tumors. Manufactured by MiNK Therapeutics in Lexington, MA, agenT-797 is a scalable, off-the-shelf product designed to provide accessible, transformative treatment options. In clinical trials, agenT-797 can bolster peripheral memory T-cell activation, enhance tumor infiltration, and potentially improve outcomes for patients with solid cancers (Cytryn et al., AACR IO 2024; Oncogene, 2024), as well as reduce inflammation in critically ill patients with severe respiratory pathology (Nature Communications, 2024). Forward Looking Statements This press release contains forward-looking statements that are made pursuant to the safe harbor provisions of the federal securities laws, including statements regarding the therapeutic potential, anticipated benefit, plans and timelines of iNKT cells. These forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially. These forward-looking statements are subject to risks and uncertainties, including the factors described under the Risk Factors section of the most recent Form 10-K, Form 10-Q and the S-1 Registration Statement filed with the SEC. MiNK cautions investors not to place considerable reliance on the forward-looking statements contained in this release. These statements speak only as of the date of this press release, and MiNK and Agenus with no obligation to update or revise the statements, other than to the extent required by law. All forward-looking statements are expressly qualified in their entirety by this cautionary statement. CONTACT: Investor Contact 917-362-1370 investor@ Media Contact 781-674-4428 communications@
Yahoo
10-06-2025
- Business
- Yahoo
MiNK Therapeutics Announces Virtual Annual Shareholders Meeting
NEW YORK, June 10, 2025 (GLOBE NEWSWIRE) -- MiNK Therapeutics, Inc. (NASDAQ: INKT), a clinical-stage biopharmaceutical company pioneering allogeneic, off-the-shelf invariant natural killer T (iNKT) cell therapies, today announced that its Annual Shareholders Meeting will begin at 9:30 a.m. ET. on June 18, 2025, and will be conducted in a virtual format only. Registration for attendees will start at 9:15 a.m. ET. To participate in the Annual Shareholders Meeting, shareholders should visit and enter the 16-digit control number found in their proxy materials. Guests may also access the meeting in listen-only mode. No control number is required for guests. Webcast Information: Date: Wednesday, June 18, 2025 Time: 9:30 a.m. ET A live webcast and replay will be accessible from the Company's website at and at About MiNK Therapeutics MiNK Therapeutics is a clinical-stage biopharmaceutical company pioneering the development of allogeneic invariant natural killer T (iNKT) cell therapies and precision-targeted immune technologies. MiNK's proprietary platform is designed to restore immune balance and drive cytotoxic immune responses across cancer, immune-mediated diseases, and pulmonary immune failure. MiNK's lead asset, AGENT-797, is an off-the-shelf, allogeneic iNKT cell therapy currently in clinical development for the treatment of graft-versus-host disease (GvHD), solid tumors, and critical pulmonary immune collapse. MiNK is also advancing a pipeline of T cell receptor (TCR)-based therapies and neoantigen discovery tools that enable tumor- and tissue-specific immune activation with broad potential application. With a scalable, cryopreserved manufacturing process and a differentiated mechanism that bridges innate and adaptive immunity, MiNK is committed to developing next-generation immune reconstitution therapies that are accessible, durable, and applicable across a wide range of indications. For more information, visit or @MiNK_iNKT. Information that may be important to investors will be routinely posted on our website and social media channels. Investor Contact917-362-1370 investor@ Media Contact781-674-4428communications@ in to access your portfolio
