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Do human lungs make blood? Here's what a popular study says
Do human lungs make blood? Here's what a popular study says

Time of India

time6 days ago

  • Health
  • Time of India

Do human lungs make blood? Here's what a popular study says

It is a basic principle in biology- blood is made in the bone marrow. It's where the cells(hematopoietic stem cells (HSCs))responsible for generating red blood cells, white blood cells, and platelets reside. But a striking study from researchers at UC San Francisco (UCSF) is rewriting that narrative. According to new findings published in Blood, the lungs also contain active blood-forming stem cells, capable of producing not only red blood cells but also platelets and key immune cells. The discovery could have direct implications for stem cell therapies and transplant medicine. The UCSF research team, backed by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH), first made this groundbreaking discovery in 2017when they found that mouse lungs were generating up to half of the animal's platelets, a surprising contribution for an organ never thought to be involved in hematopoiesis. These cells, structurally and functionally similar to bone marrow HSCs, weren't merely circulating through the lungs, but seemed to be living in there. To test how capable these cells actually were, scientists isolated HSCs from both lung and bone marrow tissue, grew them in laboratory conditions, and observed what they produced. 'Both types of HSCs thrived in our gold-standard stem cell experiment, but the lung HSC colonies made more red blood cells and megakaryocytes, while the bone marrow colonies tended to make more immune cells,' explained Mark Looney, MD, professor of medicine and laboratory medicine at UCSF and senior author of the study. Rethinking the bone marrow transplant Bone marrow transplants have long been used to treat cancers like leukemia and other blood-related conditions. They involve harvesting stem cells from a donor, often via a blood draw, and using them to rebuild a patient's blood system. But the UCSF team found that nearly 1 in 5 stem cells isolated in bone marrow transplants actually carried markers specific to lung-derived HSCs, suggesting that current stem cell harvests may be drawing from more than just the bone marrow. 'For decades, bone marrow transplants have been a lynchpin in the treatment of cancers like leukemia,' Looney said. 'The lung HSCs could prove to be a second and significant reservoir of these precious stem cells.' The team also demonstrated that human lung HSCs could restore bone marrow function in mice, a powerful indication that these cells aren't just present, they are fully operational. Why would lungs make blood? That question remains unanswered, but there are theories. 'The lungs are critical to blood circulation, so it's tantalizing to see the lung HSCs as an emergency reservoir for red blood cell and platelet production,' said Looney. One possibility is that these cells activate during times of stress or injury, when the body's demand for oxygen-carrying red cells or clot-forming platelets spikes. The lungs, always at the center of the oxygen exchange process, could provide a rapid-response supply.

Taylor Swift's dad recovering from successful heart surgery, source claims

time16-07-2025

  • Health

Taylor Swift's dad recovering from successful heart surgery, source claims

Scott Swift, the father of music superstar Taylor Swift, is reportedly recovering after undergoing heart surgery, a source close to the Swifts confirmed to ABC News. Scott Swift, 73, underwent a successful quintuple bypass surgery over one month ago, according to the source. A bypass surgery, also known as coronary artery bypass grafting, is done in order to improve the flow of blood to the heart, according to the National Heart, Lung and Blood Institute. The procedure takes healthy blood vessels from one part of the body and connects them to the blood vessels around the blocked artery, according to the NHLBI. It is used to treat obstructive coronary heart disease. TMZ was the first to report the news of Scott Swift's surgery. Taylor Swift has not commented publicly on her dad's health. The music star's family members -- including her mom Andrea Swift and brother Austin Swift -- are well-known to her fans, as they are a frequent presence by her side. Scott Swift in particular was a familiar face at concerts around the world during his daughter's blockbuster Eras Tour last year. He has also joined Taylor Swift and her mom and brother at Kansas City Chiefs games to cheer on Taylor Swift's boyfriend, tight end Travis Kelce.

Insmed Stock Soars on Pulmonary Arterial Hypertension Drug Trial Results
Insmed Stock Soars on Pulmonary Arterial Hypertension Drug Trial Results

Yahoo

time10-06-2025

  • Business
  • Yahoo

Insmed Stock Soars on Pulmonary Arterial Hypertension Drug Trial Results

Shares of Insmed (INSM) jumped nearly 30% Tuesday after the biopharmaceutical company reported positive results from a Phase 2 trial for its treatment of pulmonary arterial hypertension. The Bridgewater, N.J.-based company said the study was "evaluating the efficacy and safety of treprostinil palmitil inhalation powder" in patients with pulmonary arterial hypertension, or PAH, and that the trial "met its primary endpoint and all secondary efficacy endpoints." Pulmonary hypertension, which develops when the blood pressure in your lungs is higher than normal, affects about 1% of people globally, per the National Heart, Lung, and Blood Institute. Insmed said it would "immediately engage with the U.S. Food and Drug Administration (FDA) regarding the Phase 3 trial design for PAH. Insmed plans to initiate a Phase 3 trial in patients with pulmonary hypertension associated with interstitial lung disease before the end of 2025 and a Phase 3 trial in patients with PAH in early 2026." The news caused Insmed shares to soar nearly 28% Tuesday afternoon to around $90, their highest level in nearly a quarter century. Shares of United Therapeutics (UTHR), which makes rival PAH treatments, recently sank almost 14% to about $283, their lowest level since April. Read the original article on Investopedia Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

I thought $269 for a supplement was crazy – then I tried it
I thought $269 for a supplement was crazy – then I tried it

New York Post

time05-05-2025

  • Health
  • New York Post

I thought $269 for a supplement was crazy – then I tried it

There is a lot to discuss today when it comes to health and wellness. From synthetic dyes in, or maybe soon, not in, our food to sensational biohacker expos exhibiting all the tech tools worthy of 'The Jetsons,' it's sometimes easy to forget that we may be quite complex, but what we need to work our best is remarkably simple. However, living simply isn't always easy to come by these days, so chances are we outsource basics where we can, like supplements. It's no surprise, then, that supplements have become a go-to for people trying to cover their bases — and LYMA is one name that keeps coming up. Most people who've taken the LYMA Supplement rave about its metabolism-boosting benefits and the way it improves hair and nails. And while that's totally true, it's also a must-try for those with poor sleep. Blame doom-scrolling, blue light or too much caffeine before bed, but a startling number of folks are sleep deprived. According to the National Heart, Lung, and Blood Institute, 1 out of 3 adults don't get enough rest, and 50-70% have ongoing sleep disorders — yikes. Blame doom-scrolling, blue light, too much caffeine, or any combination of the aforementioned, depending on the day, but a startling number of Americans are sleep-deprived. According to the National Heart, Lung, and Blood Institute, one out of three adults doesn't get enough rest, and 50 to 70% have ongoing sleep disorders — yikes. While the folks at LYMA aren't marketing the supplement as a cure for insomnia, our tester, Senior Social Media Manager of Commerce Michelle Moezam, was most impressed by how it improved her Zzzs. About LYMA If you're not familiar with LYMA, I'm genuinely surprised. Along with being the maker of the celebrity-loved LYMA Laser, the company has earned numerous awards for its innovative work in the beauty and wellness space. Its Supplement, which has 11 gold-standard nutraceutical ingredients, has been on the radar of health enthusiasts since its launch. Along with enhancing focus and easing anxiety, it also boosts metabolism through the ingredient ActivAmp, an exercise mimetic. All the ingredients are patented, have been proven in peer-reviewed clinical trials, and are optimized for maximum bioavailability. LYMA Pros: Ingredients are engineered for maximum bioavailability and are patented and proven in peer-reviewed clinical trials Shown to improve sleep, metabolism, focus, skin, hair and nails Improvement can be noticed in as little as two weeks Beautiful packaging that makes it easy to remember to take the daily supplement Cons: Serving is four pills per day If you have ever wished there was a real-life 'Limitless' pill, you'll want to try this LYMA Supplement. Featuring 11 peer-reviewed ingredients, it offers better focus, reduced anxiety, a stronger metabolism, better sleep and more! Some ingredients you'll recognize, like turmeric, vitamin K, keratin, and the buzziest of buzzworthy adaptogens, ashwagandha; others you'll just be impressed with, especially once you've read the science behind each of them. Every ingredient is carefully dosed for maximum effectiveness, ensuring you receive the full benefits. More importantly, the innovative formulation removes the need to buy bottle after bottle of individual supplements (which probably don't have the concentration to be effective, if we're being honest). Whereas four pills a day feels like a lot at first, once you're used to it and understand it's all you need, it quickly becomes second nature. I noticed a change quickly, and many report improvements in as little as two weeks. Serving: 4 pills | Capsule number: 30 day supply Our review of the LYMA Supplement When Moezam read the details on the LYMA Supplement, she was eager to serve as our resident tester. As one of our team's dedicated wellness buffs (she knows all her health stats!), she was clearly the best person for the job. 'In all honesty, I was already doing my own independent research on sleep supplements,' she said. In fact, she was even 'deep diving' into which vitamin combinations were best for maximum absorption. 'It became a headache,' she admitted. 'I wanted the research to be done already. I just didn't want extra added sugars or melatonin, since those felt generic and not personalized to what I needed.' Before testing the supplement for 30 days, she took some notes on her current sleep patterns to better track any changes. She noticed every morning, she woke between 4 a.m. and 5:30 a.m. — and not on purpose. When she first started taking the LYMA Supplement, that abruptly stopped. 'This was actually the first change I noticed,' she said. 'I would still stir a bit but remember vividly being able to fall back into a little bit more REM before my 7:30 a.m. alarm.' Along with uninterrupted rest, Moezam found she fell asleep faster. Moezam's dog makes sure she takes her supplement. Michelle Moezam 'I followed the instructions closely and waited at least 30 minutes between caffeine breaks to take the daily four pills and noticed on day two how differently my body was digesting the amount of caffeine I was consuming,' she noted. 'I drank a pink Red Bull at 3 p.m. (like an idiot) and still somehow slept like a rock that night.' By day three, she was 'hooked,' with the first two nights being the 'deepest sleep' she had ever experienced. 'It was incredible to think this is how much deep sleep people are normally getting,' she mused. How the LYMA Supplement aids sleep The LYMA Supplement has several ingredients in its nutraceutical lineup that promote better sleep. Its 100% cold-water-dispersed turmeric extract, for example, is anti-inflammatory and helps ease inflammation (a sleep disrupter) by blocking inflammatory enzymes. More importantly, LYMA's patented turmeric, HydroCurc, is highly concentrated, enabling the body to absorb it more fully. The Supplement also contains an adapted version of PEA (palmitoylethanolamide), a type of fatty acid. PEA is sometimes referred to as the 'bliss molecule' and helps regulate mood, reduce pain, and improve sleep quality. Ashwagandha, an adaptogen, also plays a role, as it naturally lowers stress levels, and we all know how hard it is to sleep when your mind is spiraling! When should I take the LYMA Supplement? According to LYMA's website, the LYMA Supplement can be taken any time of day, with or without food. However, Moezam found that taking the four pills in the afternoon worked best for her. 'I noticed after a little experimenting to take them after 4 p.m. — that's at least what worked best for me — otherwise, the anti-inflammatory properties slurped up the caffeine in my body, and I found myself reaching for a second or third cup of coffee.' Supplement selfies! Michelle Moezam For those with a sensitive nose, the ingredient turmeric may cause concern; however, Moezam insists it's nothing one can't get over once the benefits start to show. 'At first sniff, the turmeric is overpowering, but as someone who grew up in a Persian household, it was also a warm and familiar scent. The copper vessel seals the scent shut, so you don't need to worry about it making your pantry smell if you are opposed to the smell of turmeric.' What are the benefits of the LYMA Supplement? The LYMA Supplement utilizes 11 rigorously researched and tested ingredients to address a range of concerns and has been shown to: Strengthen hair and nails and improve skin quality Improve sleep Lower stress and anxiety levels Ease perimenopausal symptoms in females Boost immunity Enhance focus and concentration According to LYMA's website, improvement can be seen in two weeks, but according to Moezam, you may not have to wait that long. 'It's so impressive to me the amount of research that went into the ingredient list, which also makes the price make more sense,' she noted. Another benefit she noticed was her improved tummy. 'The supplement really aided in my digestion, which isn't a shock since turmeric is known to benefit liver function and is already a part of my Middle Eastern diet,' she explained. 'I have PCOS (polycystic ovary syndrome) and always struggle with a slower metabolic rate and sugar retention. I felt like my energy levels from digestion benefited [while taking the supplement].' Who is the LYMA Supplement best for? The LYMA Supplement is suitable for both men and women seeking to holistically address issues such as sleep disturbances, anxiety, a sluggish metabolism, or simply looking for a cognitive function boost. While its luxe packaging (and price tag) suggest it's for a specific clientele, it's for anyone serious about investing in their well-being. 'Everything about the experience of taking the pills feels extremely 'rich in health' — the quality of the capsule on the tongue is quite unreal,' said Moezam, noting 'the glowing copper vessel' the pills come in, along with the bioavailability of the ingredients. The supplement's ingredients are fully traceable, making it also a premium option for those who care about transparency when it comes to their vitamins. Details about each ingredient can be found on LYMA's website, along with links to relevant studies. Alternatively, you can simply Google it, as we did, and be properly impressed by the science. LYMA Final Verdict: Is the LYMA Supplement worth it? While we won't deny that the asking price of the LYMA Supplement may give many pause, when we factor in the cost of each ingredient individually, it's actually quite fair. Also, how many other supplements do you know that address so many things at once? 'I think as consumers we begin to question, 'How can I justify spending $269 for some vitamins?'' said Moezam. 'Looking back over the past month, my sleep has noticeably improved, and my anxiety feels more manageable — even though I haven't changed anything else in my life,' Moezam shared. 'So, why should I start sacrificing that when I know I will be healthier for it? Better to invest in my health now before I need to start taking sleeping pills a decade from now. Invest now, prevent later!' How we tested To test if the LYMA Supplement was truly worth the hype (and the money), Moezam considered the following factors: Sleep quality: Before testing the supplement for 30 days, Moezam tracked her sleep patterns to set a baseline of comparison. Once she began her experiment, she jotted down any changes she experienced, including the hours she slept, how deep she slept, and her overall sleep quality. Improvements and adverse reactions: Moezam kept a journal of any changes she noticed (both positive and negative) while taking the supplement to determine if it worked/lived up to the hype. Digestibility and smell: Many people complain of stomach upset when taking supplements. While Moezam did note the smell of turmeric, she didn't find that the pills triggered reflux or an upset stomach — even when she consumed coffee. Moezam also noticed that the supplement aided in her digestion. Ingredients: To understand if the LYMA Supplement was fairly priced, Moezam did a deep dive into the ingredient list, as well as the brand's sourcing techniques and patents, to see if it was all marketing or a genuinely high-quality supplement. Price: The initial cost of the LYMA Supplement Starter Pack, which includes the elevated hammered copper vessel to safely store a month's worth of capsules, a medical-grade resealable pouch of LYMA Supplement capsules, and a LYMA Membership card, for $269. Refills, without the copper vessel or card, cost $222, unless you subscribe to a monthly plan, which takes the total to $199.80 after a 10% subscriber discount. For over 200 years, the New York Post has been America's go-to source for bold news, engaging stories, in-depth reporting, and now, insightful shopping guidance. We're not just thorough reporters – we sift through mountains of information, test and compare products, and consult experts on any topics we aren't already schooled specialists in to deliver useful, realistic product recommendations based on our extensive and hands-on analysis. Here at The Post, we're known for being brutally honest – we clearly label partnership content, and whether we receive anything from affiliate links, so you always know where we stand. We routinely update content to reflect current research and expert advice, provide context (and wit) and ensure our links work. Please note that deals can expire, and all prices are subject to change. Looking for a headline-worthy haul? Keep shopping Post Wanted.

Doctor: Take care of your heart in February
Doctor: Take care of your heart in February

Yahoo

time10-02-2025

  • Health
  • Yahoo

Doctor: Take care of your heart in February

PLATTSBURGH — Heart disease is the leading cause of death for men and women in the United States, and to raise awareness, the National Heart, Lung and Blood Institute branded February as American Heart Month. 'Why is it important to talk about heart month? Heart disease is fairly common and most people do not even know they are at risk of heart disease,' Dr. Anthony Conti, founder of Lake Champlain Imaging, said. 'Heart disease is the leading cause of death in men and women. Every 33 seconds–someone dies of heart disease. One in five are under the age of 65-years-old. When we hear these stories about this, and we all experience it ourselves, a family member, a friend, a neighbor, we all say to ourselves, 'Wow, they seemed young, who could have known?' But that is a big misconception.' According to the NHLBI, most middle-aged and young adults have one or more risk factors for heart disease, such as diabetes, high blood pressure, high cholesterol, or being a smoker or overweight. Having multiple risk factors increases the risk of heart disease. These factors include age, family history and lifestyle factors such as high blood pressure, cholesterol, smoking, poor diet and physical inactivity. 'There are factors we cannot control, like age and family history,' Dr. Conti said. 'But there are lifestyle factors that increase risk, such as high blood pressure, cholesterol, smoking, diabetes, overweight, physical inactivity and unhealthy diets.' According to the NHLBI, cardiovascular disease is the term for all types of diseases that affect the heart or blood vessels which can cause heart attacks, stroke, heart failure and peripheral artery disease. 'Heart disease' is a catch-all phrase for a variety of conditions that affect the heart's structure and function, the most common is coronary heart disease. While all heart diseases are cardiovascular diseases, not all cardiovascular diseases are heart disease. Coronary heart disease, also known as coronary artery disease, is often referred to simply as 'heart disease,' although it's not the only type of heart disease. Coronary heart disease occurs when plaque, a combination of fat, cholesterol, calcium and other substances found in the blood, builds up in your arteries. The plaque reduces the amount of oxygen-rich blood getting to the heart, which can cause chest pain, also called angina. Plaque can also lead to blood clots, which block blood flow and are the most common cause of a heart attack. According to the NHLBI, about 366,000 Americans die from coronary heart disease each year. 'Unfortunately there is no build up of symptoms. The first major symptom is a heart attack,' Dr. Conti said. 'And one in five heart attacks are silent. The damage is done and they don't even know it. They feel a pain but pass it off. There are a lot of patients in their 50s and 60s with build up and don't even know it.' Some lifestyle tips from the NHLBI to improve heart health include: • Be more physically active. • Maintain a healthy weight. • Eat a nutritious diet. • Quit smoking. • Manage stress. • Get 7-9 hours of quality sleep. • Track your blood pressure, cholesterol, and blood sugar numbers. 'Lifestyle factors are all difficult. If exercising and eating a super healthy diet was easy, we wouldn't be here. But it's no longer theoretical, it's no longer 'maybe I'll get lucky and it won't happen to me,' Conti said. Lake Champlain Imaging, on Route 3 in Plattsburgh, prides itself on a comprehensive array of radiologic imaging and cutting edge diagnostic testing by doctor recommendation to determine a patient's risk factors and how to best optimize the heart moving forward. 'The power of these tests is it removes the veil of mystery, the mystery of 'oh do I, does a loved one have heart disease,' Conti said. These tests include a Coronary Calcium Score, Coronary Calcium Score, Echocardiography, Vascular Ultrasound, Holter Monitor, Fractional Flow Reserve as well as a tool that utilizes AI to analyze plaque build up. 'I encourage people over 50-years-old to talk to their providers about their individual risks and if these tests may be right for them,' Conti said.

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