Latest news with #Obesity
Globe and Mail
20-06-2025
- Health
- Globe and Mail
Obesity Clinical Trials Appears Robust With 80+ Key Pharma Companies Actively Working in the Therapeutics Segment
DelveInsight's, ' Obesity Pipeline Insigh t 2025 ' report provides comprehensive insights about 80+ companies and 100+ pipeline drugs in Obesity pipeline landscape. It covers the Obesity pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Obesity therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive Obesity pipeline products in this space. Stay ahead with the latest insights! Download DelveInsight's comprehensive Obesity Pipeline Report to explore emerging therapies, key Obesity Companies, and future Obesity treatment landscapes @ Obesity Pipeline Outlook Report Key Takeaways from the Obesity Pipeline Report In June 2025, Carmot Therapeutics Inc. announced a Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of Once-Weekly CT-388 Administered Subcutaneously for 48 Weeks to Participants Who Are Overweight or Obese With Type 2 Diabetes Mellitus. In June 2025, Zomagen Biosciences Ltd. conducted a study to understand if taking VTX3232 alone or in combination with semaglutide is safe in participants diagnosed with Obesity. Approximately 160 patients will take VTX3232 Dose A, Placebo, VTX3232 Dose A in combination with semaglutide, or Placebo in combination with semaglutide. In June 2025, Boehringer Ingelheim organized a study is to find out whether a medicine called survodutide (BI 456906) helps people living with obesity disease to lose weight. Participants are divided into 3 groups by chance, like drawing names from a hat. 2 groups get different doses of survodutide and 1 group gets placebo. Placebo looks like survodutide but does not contain any medicine. In June 2025, Novo Nordisk A/S announced a study will look at how well CagriSema helps people living with obesity to lose weight and maintain the weight loss long-term. The study has 2 parts: The first part is called 'the main study' and the second part is called 'the extension study'. In the main study participants will either get CagriSema (a study medicine) or placebo (a dummy medicine that looks like CagriSema but has no active ingredient). Which treatment participants get is decided by chance. Participants are two times more likely to get CagriSema than placebo. If participants get CagriSema in the main study, participants will continue on CagriSema in the extension study. In June 2025, Hanmi Pharmaceutical Company Limited conducted a phase 3 study to evaluate efficacy and safety of HM11260C in adult obesity patients without diabetes mellitus. DelveInsight's Obesity pipeline report depicts a robust space with 80+ active players working to develop 100+ pipeline therapies for Obesity treatment. The leading Obesity Companies such as Zealand Pharma, Sciwind Biosciences, Genexine, Sirnaomics, Sparrow Pharmaceuticals, Shionogi, Regor Pharmaceuticals, Innovent Biologics, Pfizer, NodThera Limited, Boehringer Ingelheim, Fractyl Health, TransThera, Clearmind Medicine, PegBio, Biolingus, and others. Promising Obesity Therapies such as APHD-012, Bimagrumab, Semaglutide, CT-868, GLY-200, Bremelanotide, and others. Discover how the Obesity treatment paradigm is evolving. Access DelveInsight's in-depth Obesity Pipeline Analysis for a closer look at promising breakthroughs @ Obesity Clinical Trials and Studies Obesity Emerging Drugs Survodutide: Zealand Pharma Survodutide (BI 456906) is a long-acting glucagon/GLP-1 receptor dual agonist for once-weekly subcutaneous administration that activates two key gut hormone receptors simultaneously and may offer better efficacy than current single-hormone receptor agonist treatments. Survodutide is targeting the treatment of obesity and nonalcoholic steatohepatitis (NASH). Boehringer Ingelheim is advancing survodutide into three global Phase III trials in people living with overweight or obesity. Ecnoglutide: Sciwind Biosciences Glucagon-like peptide-1 (GLP-1) analogs are effective therapies in managing type 2 diabetes, obesity, and have demonstrated clinical potential as a treatment for NASH. Ecnoglutide (XW003) is a novel, cAMP signaling biased, long-acting GLP-1 analogue optimized for improved biological activity, cost-effective manufacturing, and once weekly dosing. Currently, the drug is in Phase III stage of its clinical trial for the treatment of Obesity. CT-868: Carmot Therapeutics CT-868 is a dual GLP-1 and GIP receptor modulator with a unique pharmacological profile optimized for improved tolerability at the GLP-1 receptor. The combined action of GLP-1 and GIP results in greater body weight loss and glucose control. CT-868 is dosed once daily to maximize efficacy and tolerability. CT-868 dual agonist candidate was discovered using the chemotype evolution technology as a peptide-small molecule hybrid compound, able to mimic the native GLP-1 hormone. In the Phase I trial, CT-868 demonstrated compelling pharmacodynamic activity across several clinical measures in overweight and obese healthy individuals a safe and generally well-tolerated profile. Carmot Therapeutics is now expanding the observations in overweight and obese patients with type 2 diabetes to demonstrate CT-868's effects on glycemic control, weight loss, and tolerability. Currently, the drug is in the Phase II stage of development to treat obesity. DD01: D&D Pharmatech DD01 is a proprietary, imbalanced dual agonist of GLP-1 and glucagon receptors with a half-life of 11 days in non-human primates. DD01 is being developed as a potential disease-modifying agent for obesity and liver fatty disease. Treatment with DD01 caused weight loss, reduced liver fat, and improved glucose tolerance in preclinical obesity, diabetes, and fatty liver models. In preclinical models of diabetes and nonalcoholic fatty liver disease (NAFLD), DD01 could reduce weight and blood sugar and improve insulin sensitivity and lipid and fat metabolism, which could ameliorate NASH. DD01 demonstrated greater efficacy in preclinical models than semaglutide, an approved GLP-1R receptor agonist; from a mechanical perspective, the effect of DD01 persisted after cessation of treatment. It is currently being evaluated in Phase I clinical trial to investigate the safety, tolerability, PK, and PD of DD01 administered by subcutaneous (SC) injection in overweight/obese subjects with type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD). The Obesity pipeline report provides insights into The report provides detailed insights about companies that are developing therapies for the treatment of Obesity with aggregate therapies developed by each company for the same. It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Obesity Treatment. Obesity Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects. Obesity Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Obesity market. Get a detailed analysis of the latest innovations in the Obesity pipeline. Explore DelveInsight's expert-driven report today! @ Obesity Unmet Needs Obesity Companies Zealand Pharma, Sciwind Biosciences, Genexine, Sirnaomics, Sparrow Pharmaceuticals, Shionogi, Regor Pharmaceuticals, Innovent Biologics, Pfizer, NodThera Limited, Boehringer Ingelheim, Fractyl Health, TransThera, Clearmind Medicine, PegBio, Biolingus, and others. Obesity pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Obesity Products have been categorized under various ROAs such as Oral Parenteral Intravenous Subcutaneous Topical Obesity Products have been categorized under various Molecule types such as Recombinant fusion proteins Small molecule Monoclonal antibody Peptide Polymer Gene therapy Download DelveInsight's latest report to gain strategic insights into upcoming Obesity Therapies and key Obesity Developments @ Obesity Market Drivers and Barriers, and Future Perspectives Scope of the Obesity Pipeline Report Coverage- Global Obesity Companies- Zealand Pharma, Sciwind Biosciences, Genexine, Sirnaomics, Sparrow Pharmaceuticals, Shionogi, Regor Pharmaceuticals, Innovent Biologics, Pfizer, NodThera Limited, Boehringer Ingelheim, Fractyl Health, TransThera, Clearmind Medicine, PegBio, Biolingus, and others. Obesity Therapies- APHD-012, Bimagrumab, Semaglutide, CT-868, GLY-200, Bremelanotide, and others. Obesity Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination Obesity Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III Which companies are leading the race in Obesity drug development? Find out in DelveInsight's exclusive Obesity Pipeline Report—access it now! @ Obesity Emerging Drugs and Major Companies Table of Contents Introduction Executive Summary Obesity Overview Obesity Pipeline Therapeutics Obesity Therapeutic Assessment Late Stage Products (Phase III) Survodutide: Zealand Pharma Drug profiles in the detailed report….. Mid Stage Products (Phase II) CT-868: Carmot Therapeutics Drug profiles in the detailed report….. Early Stage Products (Phase I) DD01: D&D Pharmatech Drug profiles in the detailed report….. Preclinical and Discovery Stage Products Drug name: Company name Drug profiles in the detailed report….. Inactive Obesity Products Obesity Key Companies Obesity Key Products Obesity Unmet Needs Obesity Market Drivers Obesity Market Barriers Obesity Future Perspectives and Conclusion Obesity Analyst Views Obesity Key Companies Appendix About Us DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve. Media Contact Company Name: DelveInsight Business Research LLP Contact Person: Yash Bhardwaj Email: Send Email Phone: 09650213330 Address: 304 S. Jones Blvd #2432 City: Las Vegas State: NV Country: United States Website:
Health Line
20-06-2025
- Health
- Health Line
GLP-1 Weight Loss Results Not as Effective in Everyday Life, Study Finds
Researchers report that people taking GLP-1 drugs in daily life don't lose as much weight as those in clinical trials who take the same medications. The researchers add that people using weight loss drugs don't regain weight as quickly as those in clinical trials. One possible reason for the weight loss differential is that people in the 'real world' tend to stop taking these medications sooner than people in clinical trials. People who use commonly prescribed weight loss medications don't lose as much weight as participants in clinical trials, but they also don't regain weight as quickly. That's the conclusion of a new study published on June 10 in the journal Obesity. The study authors reported that the weight loss differential was mainly due to the fact that people tend to stop using GLP-1 drugs sooner than clinical trial participants. They also tend to use lower doses of these medications. The researchers also reported that A1C blood level reductions were similar for both groups of people. The researchers noted that they will initiate further research into what other measures, such as lifestyle changes or bariatric surgery, people may have adopted after discontinuing weight loss medications such as Wegovy and Zepbound. The researchers also want to look into why people stopped using weight loss drugs before their program regimen ended. 'Our findings indicate that treatment discontinuation and use of lower maintenance dosages might reduce the likelihood of achieving clinically meaningful weight reduction in patients who initiate obesity pharmacotherapy with semaglutide or tirzepatide,' the study authors wrote. 'Our findings could inform the decisions of healthcare providers and their patients on the role of treatment discontinuation and maintenance dosage in achieving clinically meaningful weight loss,' they added. 'Real world' use of weight loss medications For their study, researchers looked at the health records of 7,881 adults with obesity or weight management issues who did not have type 2 diabetes. Those people were seen between 2021 and 2023 at the Cleveland Clinic's facilities in Ohio and Florida. Their average age was about 51 years. Nearly 80% of the subjects were white. Of those participants, 6,109 were prescribed a weight loss medication such as Wegovy with the active ingredient semaglutide. The other 1,772 were prescribed a weight loss drug, such as Zepbound, with the active ingredient tirzepatide. About 80% of those subjects were given low doses of their weekly injectable weight loss medications. Researchers reported significant differences between people using weight loss medications in phase 3 clinical trials and those taking the drugs in the 'real world.' For starters, about half of those taking either medication in daily life stopped within the first 12 months. About 51% of those using a tirzepatide drug discontinued its use in that same time period. That compares with only 17% of semaglutide users and between 14% and 16% of tirzepatide users in clinical trials who quit during the first year. In addition, the average weight reduction for semaglutide participants in daily life was nearly 8% after one year while it was 12% for people taking tirzepatide. By comparison, the average weight loss in clinical trials was nearly 15% for semaglutide subjects as well as 15% for people on low dose tirzepatide and 20% for those on a higher dose of that medication. In general, weight loss was greater in people who took weight loss medications for a longer period of time. In addition, about 54% of people who had prediabetes at the start of their treatment plan improved to healthier A1C levels after one year. Around 3% of those studied progressed to type 2 diabetes after 12 months. Weight loss is a long-term commitment Mir Ali, MD, a surgeon and bariatric surgeon as well as the medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California, said the main takeaway from this study is that weight loss is a long-term commitment. Ali wasn't involved in the new study. 'The long-term use of medications is more effective than short-term use,' Ali told Healthline. 'The study confirms that obesity is a chronic condition like diabetes or hypertension.' Sarah Kim, MD, a professor of medicine at the University of California San Francisco, noted that discontinuing medication is common for people being treated for obesity and other conditions. Kim was likewise not involved in the new study. Kim added that adherence to medication schedules as well as diet and exercise programs isn't as easy in real life because people don't have the supervision and support a person gets during a clinical trial. 'Real life is different and results aren't always as spectacular as in clinical trials,' Kim told Healthline. Kim and Ali agreed that another reason people stop taking medications is that these drugs can be expensive, even if insurance is picking up part of the cost. There is also the fact that the side effects from these medications can be severe for some people. Plus, people in real life sometimes just get tired of the obligation of taking a pill or injecting themselves on a regular basis. Ali and Kim also noted that people need to realize that medications are only a tool to help them eat less. To lose weight and keep it off, a person needs to adopt lifestyle habits such as a healthy diet and regular exercise. 'The medications are not a short-term kickstart. They don't burn fat,' said Kim. 'The medications just help with the suppression of hunger.' 'The ultimate goal of the medications is to give people a tool to get them to a healthy weight,' Ali added. What to know about GLP-1 drug for weight loss Glucagon-like peptide-1 receptor agonists (GLP-1s) work by mimicking a hormone in the body that helps regulate blood sugar levels and reduces hunger pangs. One class of the newer GLP-1 medications uses the active ingredient semaglutide. They are sold under different brand names. Ozempic and Rybelsus have been approved to treat type 2 diabetes. Wegovy is approved for use in weight management. Semaglutide drugs are available as both oral tablets and injections. The other newer group uses the active ingredient tirzepatide. Mounjaro is approved to treat type 2 diabetes. Zepbound is approved for use in weight management. These medications are available only as injections. Previous studies have highlighted the effectiveness of these drugs on helping people lose weight. Past research has also indicated that these weight loss drugs can help lower a person's risk of cancer as well as provide benefits to heart health and brain health. Experts say the medications have proven to be effective and their use is likely to increase. 'This is a massive market and it's not going to go away,' Ali said. 'These medications are going to continue to be a big part of weight loss programs.'
Malaysian Reserve
18-06-2025
- Health
- Malaysian Reserve
Social and Economic Factors Explain Why Black Patients Lose Less Weight After Bariatric Surgery than Other Groups
NEW YORK, June 18, 2025 /PRNewswire/ — Weight loss surgery has long been an effective treatment for the more than 40 percent of the American adults struggling with obesity. While previous studies show that Black patients lose less weight overall following bariatric surgery compared to other racial groups, less attention has been paid to the relationships between economic and social factors that may help explain differences in weight loss. New research led by NYU Langone Grossman School of Medicine found that Black patients who underwent sleeve gastrectomy, the most common weight loss surgery, between 2017 and 2020 lost 6.2 percent less weight than their White counterparts, and 4.9 percent less than Hispanic patients, after one year. However, further analyses found that a lot more complexity and interplay between non-biological factors than previously known appear to impact weight loss surgery incomes. Published online in the journal Obesity, this is the first study to investigate the relationship between a variety of economic and social factors that include income, sleep disturbances and stress, and weight loss differences among racial groups, the study authors said. 'Our findings identified variations in bariatric surgery outcomes so that we can address them and, when appropriate, offer patients individualized support that can help promote the best possible outcomes,' said Melanie Jay, MD, professor in the Departments of Medicine and Population Health at NYU Langone Health, and senior author of the study. How the Study was Conducted Study participants who self-identified as either Non-Hispanic Black, Hispanic, or Non-Hispanic White were recruited from NYU Langone Health Tisch Hospital and NYC Health + Hospital Bellevue Hospital from June 2017 to March 2020. The researchers measured patients' total weight loss, waist circumference, body composition, hormones, and blood glucose levels—following up with them at multiple intervals through in-clinic visits and questionnaires over two years. Analyzing data from 297 patients, the investigators found that after surgery, non-Hispanic Black patients lost less total weight at nearly every follow-up interval compared to their Hispanic and White counterparts. Black patients also consistently reported higher sleep disturbance, perceived stress, and experiences of discrimination. In contrast, no significant differences in total weight loss were observed between Hispanic and White patients. White patients also were found to have better long-term blood glucose control than both Black and Hispanic patients after follow-up. 'These varied associations highlight how different lived experiences and self-perceptions across racial and ethnic groups can influence surgical outcomes,' said Sally M. Vanegas, PhD, research assistant professor in the Department of Medicine and lead study author. 'Additional research is needed to better understand how a broader range of socioeconomic factors may shape these outcomes.' José O. Alemán, MD, PhD, an endocrinologist at NYU Langone and co-senior author of the study said he and his colleagues will continue analyzing data from the study participants to explore additional biological factors that may influence weight loss surgery outcomes, including changes in gene expression and the microbiome. 'As a clinical community, we have to be honest that these differences exist, as well as reinforce the importance of adopting a holistic approach to care.' In addition to Jay, Alemán and Vanegas, additional collaborators from NYU Langone Health include Silvia Curado, PhD, Boyan Zhou, PhD, Ericka N. Merriwether, PhD, Nicholas Illenberger, PhD, Evelyn Armijos, Ann Marie Schmidt, MD, Christine Ren-Fielding, Manish Parikh, MD, and Brian Elbel, PhD. The study was provided with institutional support from NYU Langone Health and obtained donor support through the J. Ira and Nicki Harris Family Foundation, an AHA Ignition Center Grant (17SFRN33590133), and the Clinical and Translational Science Institute (CTSI), which is supported by the National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, through Grant Award Number UL1TR001445. SMV was in part supported by 2T32HL098129 from the National Heart, Lung and Blood Institute. JOA was in part supported by K08DK117064 from the National Institute of Diabetes and Digestive and Kidney Diseases and the Doris Duke Foundation. MJ was in part supported by the National Heart, Lung and Blood Institute (K24 HL165161-01A1). About NYU Langone Health NYU Langone Health is a fully integrated health system that consistently achieves the best patient outcomes through a rigorous focus on quality that has resulted in some of the lowest mortality rates in the nation. Vizient Inc. has ranked NYU Langone No. 1 out of 115 comprehensive academic medical centers across the nation for three years in a row, and U.S. News & World Report recently placed nine of its clinical specialties among the top five in the nation. NYU Langone offers a comprehensive range of medical services with one high standard of care across seven inpatient locations, its Perlmutter Cancer Center, and more than 320 outpatient locations in the New York area and Florida. With $14.2 billion in revenue this year, the system also includes two tuition-free medical schools, in Manhattan and on Long Island, and a vast research enterprise. Media Inquiries: Sasha
Yahoo
18-06-2025
- Business
- Yahoo
Novo Nordisk seeks digital health partners to boost GLP-1RA weight loss outcomes
Novo Nordisk is looking to partner with digital companies at every stage of the weight loss journey to help patients lose weight more effectively and stay on track with its flagship medication, Wegovy (semaglutide). The Novo Nordisk Partner Platform (NNPP) was announced at HLTH Europe, taking place in Amsterdam from 16 to 19 June, by Anne Cathrine Fleischer, vice president of Global Obesity Consumer Engagement and New Business Models at Novo Nordisk. Fleischer said that the programme will provide more services for patients receiving its glucagon-like peptide 1 receptor agonist (GLP-1RA) semaglutide, which is marketed as Wegovy for weight loss and Ozempic in type 2 diabetes, including fitness and dietary advice. Fleischer explained: 'The idea is that we create this ecosystem or marketplace of selected solutions that people can pick and choose from, so when a patient has started treatment, we know they have received help. We know when we look at our own digital tools that when intervention is combined with those efficient weight loss medications, patients are receiving better weight loss, so we hope we can significantly improve outcomes by combining education with digital tools.' Fleischer said that while this will be available to patients through the Novo Nordisk website or Novo Care, there are also considerations to work with an app developer to ensure all the services are available in one place. 'By partnering with these players, we can provide a much better patient journey and care pathway,' Fleischer added. Novo Nordisk is hoping to partner with a company which uses artificial intelligence (AI) to scan a person's plate of food and provide them with information as to whether it is providing the necessary nutrition, notably protein, due to GLP-1RAs' association with loss of muscle mass. Novo Nordisk is also in conversation with a company offering a body composition scanner mobile app. The pharma giant is also seeking telehealth providers and pharmacies to provide medical advice to patients receiving the therapy. Novo Nordisk aims to cement itself as the leading weight loss company globally after Eli Lilly announced its therapy Zepbound (tirzepatide) resulted in more weight loss than Wegovy in a Phase III study. Earlier in June, Novo Nordisk accelerated its subcutaneous and oral versions of amycretin into Phase III trials for patients with obesity and overweight. It recently initiated two more Phase III trials of its candidate CagriSema, as well as inking an $812m partnership with Deep Apple Therapeutics to access novel compounds, not GLP-1RAs, for obesity and other diseases. The company also announced a partnership with tech heavyweight NVIDIA to advance drug discovery using cutting-edge AI technologies. "Novo Nordisk seeks digital health partners to boost GLP-1RA weight loss outcomes" was originally created and published by Medical Device Network, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Sign in to access your portfolio
Yahoo
18-06-2025
- Health
- Yahoo
Social and Economic Factors Explain Why Black Patients Lose Less Weight After Bariatric Surgery than Other Groups
NEW YORK, June 18, 2025 /PRNewswire/ -- Weight loss surgery has long been an effective treatment for the more than 40 percent of the American adults struggling with obesity. While previous studies show that Black patients lose less weight overall following bariatric surgery compared to other racial groups, less attention has been paid to the relationships between economic and social factors that may help explain differences in weight loss. New research led by NYU Langone Grossman School of Medicine found that Black patients who underwent sleeve gastrectomy, the most common weight loss surgery, between 2017 and 2020 lost 6.2 percent less weight than their White counterparts, and 4.9 percent less than Hispanic patients, after one year. However, further analyses found that a lot more complexity and interplay between non-biological factors than previously known appear to impact weight loss surgery incomes. Published online in the journal Obesity, this is the first study to investigate the relationship between a variety of economic and social factors that include income, sleep disturbances and stress, and weight loss differences among racial groups, the study authors said. "Our findings identified variations in bariatric surgery outcomes so that we can address them and, when appropriate, offer patients individualized support that can help promote the best possible outcomes," said Melanie Jay, MD, professor in the Departments of Medicine and Population Health at NYU Langone Health, and senior author of the study. How the Study was Conducted Study participants who self-identified as either Non-Hispanic Black, Hispanic, or Non-Hispanic White were recruited from NYU Langone Health Tisch Hospital and NYC Health + Hospital Bellevue Hospital from June 2017 to March 2020. The researchers measured patients' total weight loss, waist circumference, body composition, hormones, and blood glucose levels—following up with them at multiple intervals through in-clinic visits and questionnaires over two years. Analyzing data from 297 patients, the investigators found that after surgery, non-Hispanic Black patients lost less total weight at nearly every follow-up interval compared to their Hispanic and White counterparts. Black patients also consistently reported higher sleep disturbance, perceived stress, and experiences of discrimination. In contrast, no significant differences in total weight loss were observed between Hispanic and White patients. White patients also were found to have better long-term blood glucose control than both Black and Hispanic patients after follow-up. "These varied associations highlight how different lived experiences and self-perceptions across racial and ethnic groups can influence surgical outcomes," said Sally M. Vanegas, PhD, research assistant professor in the Department of Medicine and lead study author. "Additional research is needed to better understand how a broader range of socioeconomic factors may shape these outcomes." José O. Alemán, MD, PhD, an endocrinologist at NYU Langone and co-senior author of the study said he and his colleagues will continue analyzing data from the study participants to explore additional biological factors that may influence weight loss surgery outcomes, including changes in gene expression and the microbiome. "As a clinical community, we have to be honest that these differences exist, as well as reinforce the importance of adopting a holistic approach to care." In addition to Jay, Alemán and Vanegas, additional collaborators from NYU Langone Health include Silvia Curado, PhD, Boyan Zhou, PhD, Ericka N. Merriwether, PhD, Nicholas Illenberger, PhD, Evelyn Armijos, Ann Marie Schmidt, MD, Christine Ren-Fielding, Manish Parikh, MD, and Brian Elbel, PhD. The study was provided with institutional support from NYU Langone Health and obtained donor support through the J. Ira and Nicki Harris Family Foundation, an AHA Ignition Center Grant (17SFRN33590133), and the Clinical and Translational Science Institute (CTSI), which is supported by the National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, through Grant Award Number UL1TR001445. SMV was in part supported by 2T32HL098129 from the National Heart, Lung and Blood Institute. JOA was in part supported by K08DK117064 from the National Institute of Diabetes and Digestive and Kidney Diseases and the Doris Duke Foundation. MJ was in part supported by the National Heart, Lung and Blood Institute (K24 HL165161-01A1). About NYU Langone Health NYU Langone Health is a fully integrated health system that consistently achieves the best patient outcomes through a rigorous focus on quality that has resulted in some of the lowest mortality rates in the nation. Vizient Inc. has ranked NYU Langone No. 1 out of 115 comprehensive academic medical centers across the nation for three years in a row, and U.S. News & World Report recently placed nine of its clinical specialties among the top five in the nation. NYU Langone offers a comprehensive range of medical services with one high standard of care across seven inpatient locations, its Perlmutter Cancer Center, and more than 320 outpatient locations in the New York area and Florida. With $14.2 billion in revenue this year, the system also includes two tuition-free medical schools, in Manhattan and on Long Island, and a vast research enterprise. Media Inquiries: Sasha View original content to download multimedia: SOURCE NYU Langone Health System Sign in to access your portfolio
