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RSNA: AI Tool Accurately Detects Tumor Location on Breast MRI
RSNA: AI Tool Accurately Detects Tumor Location on Breast MRI

Yahoo

time4 days ago

  • Health
  • Yahoo

RSNA: AI Tool Accurately Detects Tumor Location on Breast MRI

An AI model trained to detect abnormalities on breast MR images accurately depicted tumor locations and outperformed benchmark models when tested in three different groups, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA). OAK BROOK, Ill., July 15, 2025 /PRNewswire-PRWeb/ -- An AI model trained to detect abnormalities on breast MR images accurately depicted tumor locations and outperformed benchmark models when tested in three different groups, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA). "AI-assisted MRI could potentially detect cancers that humans wouldn't find otherwise," said the study's lead investigator Felipe Oviedo, Ph.D., a senior research analyst at Microsoft's AI for Good Lab. Screening mammography is considered the standard of care in breast cancer screening. However, mammography is less effective in patients with dense breasts. Breast density is an independent risk factor for breast cancer and can mask a tumor. Physicians may order breast MRI to supplement screening mammography for women who have dense breasts and those at high risk for cancer. "MRI is more sensitive than mammography," Dr. Oviedo said. "But it's also more expensive and has a higher false-positive rate." To enhance the accuracy and efficiency of screening breast MRI, Dr. Oviedo's research team closely collaborated with clinical investigators in the Department of Radiology at the University of Washington to develop an explainable AI anomaly detection model. Anomaly detection models distinguish between normal and abnormal data, flagging the anomalies, or abnormalities, for further investigation. "Previously developed models were trained on data of which 50% were cancer cases and 50% were normal cases, which is a very unrealistic distribution," Dr. Oviedo said. "Those models haven't been rigorously evaluated in low-prevalence cancer or screening populations (where 2% of all cases or less are cancer), and they also lack interpretability, both of which are essential for clinical adoption." To address these limitations, the researchers trained their model using data from nearly 10,000 consecutive contrast-enhanced breast MRI exams performed at the University of Washington between 2005 and 2022. Patients were predominately white (greater than 80%), and 42.9% had heterogeneously dense breasts, while 11.6% had extremely dense breasts. "Unlike traditional binary classification models, our anomaly detection model learned a robust representation of benign cases to better identify abnormal malignancies, even if they are underrepresented in the training data," Dr. Oviedo said. "Since malignancies can occur in multiple ways and are scarce in similar datasets, the type of anomaly detection model proposed in the study is a promising solution." In addition to providing an estimated anomaly score, the detection model produces a spatially resolved heatmap for an MR image. This heatmap highlights in color the regions in the image that the model believes to be abnormal. The abnormal regions identified by the model matched areas of biopsy-proven malignancy annotated by a radiologist, largely surpassing the performance of benchmark models. The model was tested on internal and external datasets. The internal dataset consisted of MRI exams performed on 171 women (mean age 48.8) for screening (71.9%; 31 cancers confirmed on subsequent biopsy) or pre-operative evaluation for a known cancer (28.1%; 50 cancers confirmed by biopsy). The external, publicly available, multicenter dataset included pre-treatment breast MRI exams of 221 women with invasive breast cancer. The anomaly detection model accurately depicted tumor location and outperformed benchmark models in grouped cross-validation, internal and external test datasets, and in both balanced (high prevalence of cancer) and imbalanced (low cancer prevalence) detection tasks. If integrated into radiology workflows, Dr. Oviedo said the anomaly detection model could potentially exclude normal scans for triage purposes and improve reading efficiency. "Our model provides an understandable, pixel-level explanation of what's abnormal in a breast," he said. "These anomaly heatmaps could highlight areas of potential concern, allowing radiologists to focus on those exams that are more likely to be cancer." Before clinical application, he said the model needs to be evaluated in larger datasets and prospective studies to assess its potential for enhancing radiologists' workflow. ### "Cancer Detection in Breast MRI Screening via Explainable AI Anomaly Detection." Collaborating with Dr. Oviedo were Anum S. Kazerouni, Ph.D., Philipp Liznerski, Ph.D., Yixi Xu, Ph.D., Michael Hirano, M.S., Robert A. Vandermeulen, Ph.D., Marius Kloft, Ph.D., Elyse Blum, M.D., Ph.D., Adam M. Alessio, Ph.D., Christopher I. Li, M.D., Ph.D., William B. Weeks, M.D., Ph.D., M.B.A., Rahul Dodhia, Ph.D., Juan M. Lavista Ferres, Ph.D., Habib Rahbar, M.D., and Savannah C. Partridge, Ph.D. Radiology is edited by Linda Moy, M.D., New York University, New York, N.Y., and owned and published by the Radiological Society of North America, Inc. ( RSNA is an association of radiologists, radiation oncologists, medical physicists and related scientists promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Illinois. ( For patient-friendly information on breast MRI, visit Media Contact Linda Brooks, Radiological Society of North America (RSNA), 630-590-7762, lbrooks@ View original content: SOURCE Radiological Society of North America (RSNA) Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

Arsenal legend Santi Cazorla, 40, agrees new deal with boyhood club on minimum wage after promotion to LaLiga
Arsenal legend Santi Cazorla, 40, agrees new deal with boyhood club on minimum wage after promotion to LaLiga

Scottish Sun

time6 days ago

  • Sport
  • Scottish Sun

Arsenal legend Santi Cazorla, 40, agrees new deal with boyhood club on minimum wage after promotion to LaLiga

Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) SANTI CAZORLA has signed a new one-year deal with boyhood club Real Oviedo aged 40 — and will earn MINIMUM WAGE in La Liga. The former Arsenal midfielder made an emotional return to Oviedo in 2023, playing a starring role in last season's promotion back to the Spanish top flight for the first time in 24 years. Sign up for Scottish Sun newsletter Sign up 5 Santi Cazorla has signed a new one-year deal with Real Oviedo Credit: Getty 5 Cazorla is willing to pay for free but is prevented from doing so by Spanish football rules Credit: Getty 5 Cazorla led the Real Oviedo party after they made it back to La Liga Credit: EPA 5 The players celebrated the occasion with an open-top bus parade Credit: EPA He netted a stunning free-kick in their La Liga 2 play-off semi-final against Almeria. And then scored a penalty in the second leg of the final to beat CD Mirandes in extra time. Cazorla offered to play at Oviedo — where he was in the academy from the age of eight to 16 — for FREE on his return, but league rules forced him to take a minimum wage of £77,000-a-year, or £1,480-per-week. Following Oviedo's promotion, he has signed on for the minimum possible amount again. But, as he steps up a level, he will now pocket a £90k pay-rise - as the LaLiga minimum wage is £168,000-a-year, or £3,230-a-week. That means Real Madrid's Kylian Mbappe will be earning THREE TIMES more in a WEEK than Cazorla gets a year, to play in the same league. And even then, the generous star will give 10 per cent of his wage and shirt sales to the club's academy. A club statement read: 'With this renewal, Santi Cazorla, a symbol and emblem of Oviedo, proves that dreams, when pursued with the heart, come true. BEST ONLINE CASINOS - TOP SITES IN THE UK 'Real Oviedo secures the leadership of a footballer who embodies the club's values like few others, both on and off the field.' Cazorla, who turns 41 in December, scored five goals and registered five assists in 35 games last season. Footballer Andy Carroll signing for Dagenham and Redbridge FC 5 Skin from arm had to be put on his ankle after surgery Credit: Offside sports A two-time European champion with Spain, the midfielder spent six years at Arsenal and made 180 appearances before leaving in 2018. He suffered an Achilles injury in October 2016, going on to have 11 operations to cure the problem. One of the operations led to gangrene with doctors telling Cazorla he should be satisfied to walk again, never mind play. It was even suggested he may have to have to lower leg AMPUTATED. But he ignored that doomsday prognosis and after an operation to rebuild his Achilles — including having a skin graft from his arm to his ankle — he returned to playing after a 22-month absence. Oviedo's first La Liga fixture is away at Villarreal — another former club of Cazorla's — on August 15 before hosting Jude Bellingham's Real Madrid.

Arsenal legend Santi Cazorla, 40, agrees new deal with boyhood club on minimum wage after promotion to LaLiga
Arsenal legend Santi Cazorla, 40, agrees new deal with boyhood club on minimum wage after promotion to LaLiga

The Sun

time6 days ago

  • Sport
  • The Sun

Arsenal legend Santi Cazorla, 40, agrees new deal with boyhood club on minimum wage after promotion to LaLiga

SANTI CAZORLA has signed a new one-year deal with boyhood club Real Oviedo aged 40 — and will earn just over £3,000-per-week in La Liga. The former Arsenal midfielder returned to Oviedo in 2023, playing a starring role in last season's promotion back to the Spanish top flight for the first time in 24 years. 2 2 He netted a stunning free-kick in their La Liga 2 play-off semi-final against Almeria before scoring a penalty in the second leg of the final to beat CD Mirandes in extra time. Cazorla offered to play at Oviedo — where he was in the academy from the age of eight to 16 — for free, but La Liga 2 regulations forced him to take a minimum wage of £77,000-a-year or £1,480-per-week. Following Oviedo's promotion, he will now earn the La Liga minimum wage of £168,000-a-year or £3,230-a-week — but continuing an agreement that 10 per cent of his wage and shirt sales will go towards the academy. A club statement read: 'With this renewal, Santi Cazorla, a symbol and emblem of Oviedo, proves that dreams, when pursued with the heart, come true. 'Real Oviedo secures the leadership of a footballer who embodies the club's values like few others, both on and off the field.' Cazorla, who turns 41 in December, scored five goals and registered five assists in 35 games last season. A two-time European champion with Spain, the midfielder spent six years at Arsenal and made 180 appearances before leaving in 2018. He suffered an Achilles injury in October 2016, going on to have 11 operations to cure the problem. One of the operations led to gangrene with doctors telling Cazorla he should be satisfied to walk again, never mind play. But he ignored that doomsday prognosis and after an operation to rebuild his Achilles — including having a skin graft from his arm to his ankle — he returned to playing after a 22-month absence. Oviedo's first La Liga fixture is away at Villarreal — another former club of Cazorla's — on August 15 before hosting Jude Bellingham's Real Madrid.

Cazorla, 40, signs new Oviedo deal before La Liga return
Cazorla, 40, signs new Oviedo deal before La Liga return

Yahoo

time7 days ago

  • Sport
  • Yahoo

Cazorla, 40, signs new Oviedo deal before La Liga return

Santi Cazorla scored five goals in 35 last season as Real Oviedo secured promotion via the La Liga 2 play-offs [Getty Images] Former Arsenal midfielder Santi Cazorla, 40, has signed a new one-year contract with boyhood club Real Oviedo as they prepare to return to the Spanish top flight. Cazorla who returned to the club 2023, played a key role last season as Oviedo won promotion to La Liga for the first time in 24 years. Advertisement He scored the decisive goal in the La Liga 2 play-off semi-final tie against Almeria, coming off the bench to convert a free-kick and secure a 3-2 aggregate victory. The former Spain international then scored a penalty in the second leg of the final as they beat CD Mirandes in extra time. "With this renewal, Santi Cazorla, a symbol and emblem of Oviedo, proves that dreams, when pursued with the heart, come true," the Asturian club said. "Real Oviedo secures the leadership of a footballer who embodies the Club's values like few others, both on and off the field." Cazorla who turns 41 in December, scored five goals and registered five assists in 35 games last season. Advertisement A two-time European champion with Spain, the midfielder spent six years at Arsenal and made 180 appearances before leaving in 2018. He suffered an Achilles injury in October 2016, going on to have 11 operations to cure the problem. One of the operations led to gangrene with doctors telling Cazorla he should be satisfied to walk again, never mind play.

Cazorla, 40, signs new Oviedo deal before La Liga return
Cazorla, 40, signs new Oviedo deal before La Liga return

BBC News

time7 days ago

  • Sport
  • BBC News

Cazorla, 40, signs new Oviedo deal before La Liga return

Former Arsenal midfielder Santi Cazorla, 40, has signed a new one-year contract with boyhood club Real Oviedo as they prepare to return to the Spanish top who returned to the club 2023, played a key role last season as Oviedo won promotion to La Liga for the first time in 24 scored the decisive goal in the La Liga 2 play-off semi-final tie against Almeria, coming off the bench to convert a free-kick and secure a 3-2 aggregate former Spain international then scored a penalty in the second leg of the final as they beat CD Mirandes in extra time."With this renewal, Santi Cazorla, a symbol and emblem of Oviedo, proves that dreams, when pursued with the heart, come true," the Asturian club said."Real Oviedo secures the leadership of a footballer who embodies the Club's values like few others, both on and off the field."Cazorla who turns 41 in December, scored five goals and registered five assists in 35 games last season. A two-time European champion with Spain, the midfielder spent six years at Arsenal and made 180 appearances before leaving in suffered an Achilles injury in October 2016, going on to have 11 operations to cure the of the operations led to gangrene with doctors telling Cazorla he should be satisfied to walk again, never mind play.

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