Latest news with #Paulson
Yahoo
09-07-2025
- Health
- Yahoo
These 5 Early Alzheimer's Warning Signs Are Often Mistaken for Normal Aging
You totally spaced on grabbing your gym bag (or apartment cell phone...) on your way to work in the morning. Or, you forgot to submit your cable bill payment online last week. Hey, no judgment—when it comes to getting older, forgetting stuff is part of the deal. But what if your memory loss doesn't seem like a typical part of getting older, and this is happening, like, all the time? If you're a woman, that's a serious question to consider. Two-thirds of all Alzheimer's patients and caregivers are female, according to the Women's Alzheimer's Movement, meaning women are disproportionately affected by the disease. While the reasons behind that reality aren't totally clear, hormones are likely at play. 'Women who have had hysterectomies, gone through early menopause, or had any early loss of estrogen are particularly vulnerable,' says David A. Merrill, MD, PhD, neurologist and geriatric psychiatrist at Providence Saint John's Health Center in Santa Monica. 'We know estrogen has a protective effect on the brain and supports healthy brain function.' To make matters worse, Dr. Merrill says the psychological and cognitive processes of getting older mimic the early warning signs of dementia syndromes (Alzheimer's is the most common one). So it can be easy to dismiss these first signs of brain degeneration as run-of-the-mill aging. Getting familiar with the early and first signs of the disease here—straight from neurologists!—will make you that much more prepared to take action if and when you notice something seems off with you or someone you love down the line. You're about to order your a.m. latte from your local coffee shop when you realize you can't remember the barista's she serves you five days a week. Is that bad? Probably not, says Henry Paulson, MD, PhD, neurologist and director of the University of Michigan's Alzheimer's Disease Center. 'As we age, our brains change,' he says. 'It's normal for things like our speed of thinking and recall of names to slow down.' Alzheimer's-related memory loss is more than just not being able to remember someone's name. '[We're talking about] forgetting major events or having a loss of whole episodes,' Dr. Paulson explains. For example, 'You don't remember going on a beach vacation for three days with your family or attending your grandchild's birthday party last weekend,' he says. Paulson adds that misplacing items—like consistently putting your car keys in the fridge or not knowing what room to find your toothbrush—also falls under the umbrella of memory loss, along with not knowing what day of the week or month it is. One more thing: Sometimes people will rely too heavily on tricks like repetition or note-taking to force themselves to remember things they know they'll forget—so if you (or a loved one) notice you're doing this, it's worth seeing a neurologist. If you're struggling with speaking or writing or experiencing visual impairments, it's also time to contact your doc. Early brain degeneration can make it hard to communicate and engage with your environment. 'You might notice spatial changes in your vision or even have difficulty perceiving the world around you,' explains Dr. Paulson. 'When you speak, you're having to take the long way around and come up with other phrases to explain what you need because you can't remember the exact word.' Again, these problems go beyond squinting at the television from across the room or writing the wrong date on your checks, which are all normal parts of aging; early Alzheimer's symptoms would likely be more obvious and ongoing. There are several red flags to look out for within this category, including trouble completing tasks, problem-solving, and displaying poor judgment. According to Dr. Paulson, our brains have to process a range of information in order to productively move through our day-to-day lives. The degeneration brought on by early Alzheimer's can make something as simple as choosing what to order for lunch a complicated decision. People in early stages of the disease may show other signs of cognitive deterioration such as being unable to follow directions or recipes, making serious financial errors, or struggling to maintain a healthy hygiene routine, per the Alzheimer's Association. Did you (or your aging mother, perhaps) used to be the life of every party—but now you're staying home more and more often from social gatherings? You could be experiencing a normal decrease in it could be an early warning sign of Alzheimer's. Dr. Paulson says when brain degeneration makes it hard to remember commitments, participate in conversations, or engage fully in social events, many people begin to withdraw from these activities. Sometimes this is a symptom of depression (which also shouldn't be ignored), but either way it's important to seek help if someone's behavior seems out of character for them. Speaking of out-of-character behavior, when you or someone you love starts acting like a total stranger, it's time to take those changes seriously. 'This is a little more rare, but we do see it in the early stages,' says Dr. Paulson. 'It looks like someone who knows right from wrong suddenly becoming uninhibited, and doing things they never would normally do.' It may also manifest as a person having intense mood swings, becoming easily suspicious of others, or showing heightened aggression or sexual behaviors, per the National Institute on Aging. So if you're experiencing little memory flubs before your 60s, it's unlikely you're dealing with Alzheimer's symptoms (although you should always check in with your doctor if you're concerned). And if you need help determining the next steps for yourself or a loved one, the Alzheimer's Association offers a 24/7 helpline, patient and caregiver resources, and a directory of local support groups for people affected by the disease. You Might Also Like Jennifer Garner Swears By This Retinol Eye Cream These New Kicks Will Help You Smash Your Cross-Training Goals

AU Financial Review
22-06-2025
- Business
- AU Financial Review
The art of (closing) the deal is a minefield for merger arb funds
Fifteen years ago, John Paulson found himself immortalised in The Greatest Trade Ever, a bestseller that recounted how the hedge fund manager made billions of dollars betting on the collapse of the US housing market. But Paulson's epic trade was one he should not have made. His real expertise, and where he had spent most of his career until that point, was making smaller, more mundane bets on whether corporate mergers were completed.


CNBC
18-06-2025
- Business
- CNBC
Stocks making the biggest moves midday: Nucor, Sunrun, Affirm, Zoetis, Circle and more
Check out the companies making headlines in midday trading. Steel stocks– Shares of steel producer Nucor jumped more than 3%. The company issued rosy guidance for its second-quarter earnings, calling for $2.55 to $2.65 per share, while FactSet consensus estimates sought $2.36 per share. In contrast, Steel Dynamics' guidance fell short of Wall Street's estimates, ranging from $2.00 to $2.04 per share, while analysts were looking for $2.73 per share. The stock slipped 1%. The moves follow the completion of the Nippon Steel-U.S. Steel deal . Shares of peer companies Cleveland-Cliffs and Reliance were little changed. Scholar Rock Holding — Shares jumped nearly 15% after the biotech reported its experimental drug showed it was able to help patients taking Eli Lilly 's obesity drug lose less muscle as they shed pounds. Lilly shares were down slightly. Affirm — The consumer finance stock rose 3% after Affirm announced the creation a new loan sale facility with Prudential's PGIM Fixed Income business. Prudential will buy as much as $500 million of Affirm's consumer loans at any one time, with a total investment of $3 billion over the next three years. Sunrun — Shares of the solar company rose 5% despite a downgrade to sector perform from outperform by RBC Capital Markets. The stock on Tuesday recorded its biggest one-day loss in its history amid a sell-off in solar names. Other solar stocks including Enphase Energy , which was up nearly 5%, and Solaredge , which gained 7%, were also higher. Bausch Health — Shares climbed 8% after John Paulson, its nonexecutive chair, acquired 3.6 million shares of the pharma company's stock. The purchase came on the heels of a $14.7 million purchase disclosed last week. Paulson now owns about 9% of the company's outstanding stock. CERo Therapeutics Holdings — Stock in the immunotherapy company pulled back more than 30%. On Tuesday, the U.S. Food and Drug Administration gave the company's acute myeloid leukemia drug CER-1236 an orphan drug designation . Shares rose more than 188% on that news. Chemours — The chemical stock rose 8% after an updated second-quarter forecast showed weakness in a key profit metric. Chemours said it expects consolidated adjusted EBITDA — or earnings before interest, taxes, depreciation and amortization — of $215 million to $225 million for the period. Wall Street expectations called for $236 million, according to FactSet. Regencell Bioscience — Shares dropped 26% after an eyewatering move higher this week . The Hong Kong-based developer of traditional Chinese herbal treatments has said it can treat childhood ADHD and autism. Regencell jumped 30% on Tuesday, and soared 283% Monday, following a 38-for-1 stock split. It's gained more than 59,000% this year. Oracle — The software company gained more than 1% after Guggenheim raised its price target on the stock to the highest on the Street. Analyst John DiFucci said Oracle is "on the precipice of a narrative shift that has been decades of technology innovation in the making." Zoetis — Shares of the animal health company slipped 3% following a downgrade at Stifel to hold from buy. The firm said it expects Zoetis' revenue growth to decelerate further amid increasing competition. Korn Ferry — Shares of the consulting firm gained 9% after fourth-quarter results surpassed analyst estimates on the top and bottom line. Korn Ferry earned $1.32 per share, excluding items, on revenue of $712 million. Analysts polled by FactSet expected a profit of $1.26 per share and revenue of $689.9 million. Circle Internet Group — Stock in the company behind stablecoin USDC advanced almost 16%, after the U.S. Senate passed the GENIUS bill . The legislation is the first of its kind and establishes federal guidelines for digital dollars that are pegged to the greenback. — CNBC's Brian Evans, Sarah Min, Michelle Fox, Alex Harring, Fred Imbert, Yun Li, Jesse Pound and Darla Mercado contributed reporting.
Yahoo
13-06-2025
- Entertainment
- Yahoo
American Horror Story Season 13: Ryan Murphy Says He and Sarah Paulson Are ‘Cooking Up Something Cool'
At this point, American Horror Story fans will take any information they can get about the show's elusive Season 13 — so what better day for Ryan Murphy to throw us a few crumbs than Friday the 13th? In the comments section of a first look at Ryan Murphy Productions' American Love Story, shared to Instagram on Friday, a fan asked the producer, 'Ryan, are we getting AHS13 this year? Or not in 2025?' To that, Murphy simply replied, 'Sarah Paulson and I are cooking up something cool!' More from TVLine Alien: Earth Stars Promise 'Drooling, Snarling' Xenomorphs, Say Series Is 'Tense' and 'Not Just Jump Scares' Dave Nemetz Reviews Adults: FX's Hilarious Gen Z Sitcom Gives TV a Much-Needed Youth Infusion Save the Dates: Ethan Hawke's Lowdown, Wicked Live Musical Special and More Murphy has been relatively (and very characteristically) mum about the future of American Horror Story. Speaking with The Hollywood Reporter back in October 2024, he teased that Season 13 was coming 'sooner than you think,' adding that he 'was talking to Sarah Paulson and Evan Peters about that the other day.' Paulson further fanned the flames of speculation during a subsequent Good Morning America interview. 'I would like to do it more than anything,' she said of Season 13. 'If I could be reunited with Evan Peters and Ryan Murphy, you can pretty much tell me what time I will be there, and I will be there.' That said, the fact that Murphy only mentioned Paulson in his latest comment gives us reason to think Peters may not be involved after all. The waiting continues. Paulson most recently appeared in Season 10, American Horror Story: Double Feature, playing both a drug addict named 'Tuberculosis Karen' in the first half, then real-life first lady Mamie Eisenhower in the second half. (The range!) Peters' latest Horror Story stint also came in Season 10; he played an eccentric writer named Austin Sommers. The show's most recent season — American Horror Story: Delicate, which starred Emma Roberts as a desperate actress caught in the clutches of a supernaturally evil publicist, played by Kim Kardashian — aired in two parts between September 2023 and April 2024. What are your hopes for American Horror Story Season 13, either in casting or in theme? Drop a comment with your thoughts below. All 12 American Horror Story Seasons Ranked View List Best of TVLine 'Missing' Shows, Found! Get the Latest on Ahsoka, Monarch, P-Valley, Sugar, Anansi Boys and 25+ Others Yellowjackets Mysteries: An Up-to-Date List of the Series' Biggest Questions (and Answers?) The Emmys' Most Memorable Moments: Laughter, Tears, Historical Wins, 'The Big One' and More
Yahoo
12-06-2025
- Health
- Yahoo
Ask the Expert: Is CBD oil safe and effective?
GREENVILLE, S.C. (WSPA)— Products containing CBD are growing in popularity and availability. As part of our 'Ask the Expert' series, in partnership with Bon Secours St. Francis, 7NEWS spoke with a family medicine physician about CBD oil and whether it's safe and effective. CBD oil is a product made from cannabidiol found in the cannabis plant, the same plant that produces marijuana, but doctors say it will not get you high. 'Unlike THC, which is tetrahydrocannabinol, a psychoactive compound in cannabis, CBD is non-psychoactive, meaning it does not cause a high sensation,' said Dr. Ryan Paulson. Family medicine physician Dr. Ryan Paulson said once CBD is extracted from the cannabis plant, it is usually diluted with a carrier oil such as coconut oil or hempseed oil before being used in most commercial products. He says doctors may recommend it for a variety of ailments. 'Common conditions where CBD oil can be recommended include chronic pain, anxiety, stress, sleep disorders, epilepsy or seizure disorders, inflammatory or autoimmune conditions such as Crohn's disease, ulcerative colitis, and skin conditions such as acne, eczema, or psoriasis,' said Dr. Ryan Paulson. Generally, Dr. Paulson says CBD oil is safe for most people when used appropriately, but it's not recommended for everyone. 'There are definitely individuals who should not be utilizing CBD oil or should be using it with great caution… it can interact with certain medications or underlying health conditions. 'We strongly urge that we avoid use with pregnant or breastfeeding women, as there is limited research on the safety of CBD during pregnancy and breastfeeding; in children under the age of 18; people with liver issues; and those on certain medications such as warfarin, antidepressants, and benzodiazepines,' said Dr. Ryan Paulson. Dr. Paulson says research on CBD oil is still evolving, and interactions with other treatments can vary. Therefore, consult your doctor before using these products. 'Your doctor can provide personalized guidance on proper dosage, potential interactions with other medications, and the best CBD products for your needs. That can also help you avoid any risk and ensure your overall treatment plan is effective and safe,' said Dr. Ryan Paulson. In some cases, a doctor may prescribe CBD oil as part of their treatment plan. 'Particularly for certain medical conditions where there's strong evidence for its effectiveness,' said Dr. Ryan Paulson. If you plan to purchase CBD oil over the counter, Dr. Paulson advises, ensure it's legitimate. 'To ensure you are purchasing a legitimate and safe CBD oil, you always want to look for third-party lab testing. Check the source and quality of the hemp and avoid brands that make unrealistic claims,' said Dr. Ryan Paulson. To submit a health topic for our 'Ask the Expert' series, click here. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.