Latest news with #PredictiveOncology
Associated Press
12-06-2025
- Business
- Associated Press
Predictive Oncology Develops Functional 3D Organoid Models Exclusively for Labcorp
PITTSBURGH, June 12, 2025 (GLOBE NEWSWIRE) -- Predictive Oncology Inc. (NASDAQ: POAI), a leader in AI-driven drug discovery, announced today the company has successfully developed 3D organoid models exclusively for Labcorp (NYSE: LH), a global leader of innovative and comprehensive laboratory services. As part of an ongoing agreement, Predictive Oncology recently developed two distinct and unique 3D liver toxicity models exclusively for Labcorp, including a human and rat model. Both models represent the liver microenvironment and can be used for the evaluation of both drug metabolism and liver toxicity related to drugs. 'The intention of these 3D organoid models is to enable the prediction of in vivo drug clearance, drug transport and hepatotoxicity related to drugs,' said Dr. Arlette Uihlein, Senior Vice President Translational Medicine and Drug Discovery for Predictive Oncology. 'These models provide highly relevant, species-specific data based on their physiologic hepatic microenvironments while also capturing hepatic cellular heterogeneity.' These and other 3D organoid models developed by Predictive Oncology substantially complement its AI-driven 2D platform and 3D spheroids, which utilize human tumor samples to accelerate drug discovery and identify relevant biomarkers across thousands of patients. The platform relies on Predictive Oncology's vast biobank of over 150,000 frozen tumor samples. 'Labcorp is committed to developing and using new approach methodologies (NAMs) in preclinical studies. These models show great promise to enable more rapid evaluation of new potential medicines and help accelerate their availability to patients,' said John Kendrick, Ph.D., NAMs scientific strategy lead at Labcorp. 'With this foundation in place, Labcorp will consider expanding this work into other species to support wider preclinical analyses and translate between animal and human models for these new alternative approaches.' According to Grand View Research, with the growing investment in personalized medicine and biotechnology, organoid-based platforms are key drivers to disrupting healthcare, accelerating drug development, reducing reliance on animal models, and paving the way for next-generation therapeutic solutions. Organoids are transforming disease modeling, drug discovery, and regenerative medicine, offering cost-effective and high-fidelity alternatives to traditional research methods. The functional 3D organoid models developed for Labcorp with specialized matrices and media supplements provide insights into cancer therapeutic behavior in patients. Data sets demonstrating optimal liver morphology and function were generated, including cell junction formation (ZO-1 staining); transferrin staining within hepatocytes; DCFDA staining for hepatotoxicity measurements; canalicular structure visualization; and cell viability confirmation (up to 14 days). About Predictive Oncology Predictive Oncology is on the cutting edge of the rapidly growing use of artificial intelligence and machine learning to expedite early drug discovery and enable drug development for the benefit of cancer patients worldwide. The company's scientifically validated AI platform, PEDAL, is able to predict with 92% accuracy if a tumor sample will respond to a certain drug compound, allowing for a more informed selection of drug/tumor type combinations for subsequent in-vitro testing. Together with the company's vast biobank of more than 150,000 assay-capable heterogenous human tumor samples, Predictive Oncology offers its academic and industry partners one of the industry's broadest AI-based drug discovery solutions, further complimented by its wholly owned CLIA laboratory facility. Predictive Oncology is headquartered in Pittsburgh, PA. Investor Relations Contact: Mike Moyer LifeSci Advisors, LLC [email protected] Forward-Looking Statements Certain statements made in this press release are 'forward-looking statements' within the meaning of the 'safe harbor' provisions of the Private Securities Litigation Reform Act of 1995. These forward- looking statements reflect Predictive Oncology's current expectations and projections about future events and are subject to substantial risks, uncertainties and assumptions about Predictive Oncology's operations and the investments Predictive Oncology makes. All statements, other than statements of historical facts, included in this press release regarding our strategy, future operations, future financial position, future revenue and financial performance, projected costs, prospects, changes in management, plans and objectives of management are forward-looking statements. The words 'anticipate,' 'believe,' 'estimate,' 'expect,' 'intend,' 'may,' 'plan,' 'would,' 'target' and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Predictive Oncology's actual future performance may materially differ from that contemplated by the forward-looking statements as a result of a variety of factors including, among other things, factors discussed under the heading 'Risk Factors' in Predictive Oncology's filings with the SEC. Except as expressly required by law, Predictive Oncology disclaims any intent or obligation to update these forward-looking statements. Predictive Oncology does not give any assurance that Predictive Oncology will achieve its expectations described in this press release.
Yahoo
23-05-2025
- Business
- Yahoo
Renovaro Inc. Accelerates 2025 Lawsuit to Force Predictive Oncology Merger
Renovaro Inc. (NASDAQ:RENB) stated that the Delaware Court of Chancery has granted an expedited trial to its action against Predictive Oncology Inc. (NASDAQ:POAI), which was filed on May 9, 2025. A laboratory technician researching a sample of cells in a biotechnology laboratory. A binding merger agreement signed on January 1, 2025, which called for Predictive Oncology to merge into Renovaro Inc. (NASDAQ:RENB) in exchange for a new class of preferred stock, is being enforced in this action (No. 2025-0509). According to Renovaro's complaint, POAI violated the terms of exclusivity and good faith by launching a $545,000 public securities offering on February 19, 2025, and then making an attempt to unilaterally end the agreement on April 3, 2025. Renovaro Inc. (NASDAQ:RENB) is seeking damages, injunctive relief, and specific performance. The case focuses on a Letter Agreement that caused POAI's share price to rise by more than 50% and was made public in a January 6, 2025, Form 8-K. Renovaro Inc. (NASDAQ:RENB) asserts that POAI's activities, which breached the agreed-upon confidentiality and did not participate in substantive negotiations toward a final agreement, violated the conditions of the merger. Renovaro Inc. (NASDAQ:RENB) is a TechBio business that specializes in cancer treatments, drug development, and diagnostics. Among its subsidiaries are BioSymetrics (AI for precision neurology), RenovaroBio (cell-gene immunotherapy), and RenovaroCube (AI-driven diagnostics and drug development). Concerns about shareholder value and legal attempts to uphold M&A agreements are brought to light in this case. While we acknowledge the potential of RENB to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than RENB and that has 100x upside potential, check out our report about this READ NEXT: and .
Yahoo
23-05-2025
- Business
- Yahoo
Renovaro Inc. Accelerates 2025 Lawsuit to Force Predictive Oncology Merger
Renovaro Inc. (NASDAQ:RENB) stated that the Delaware Court of Chancery has granted an expedited trial to its action against Predictive Oncology Inc. (NASDAQ:POAI), which was filed on May 9, 2025. A laboratory technician researching a sample of cells in a biotechnology laboratory. A binding merger agreement signed on January 1, 2025, which called for Predictive Oncology to merge into Renovaro Inc. (NASDAQ:RENB) in exchange for a new class of preferred stock, is being enforced in this action (No. 2025-0509). According to Renovaro's complaint, POAI violated the terms of exclusivity and good faith by launching a $545,000 public securities offering on February 19, 2025, and then making an attempt to unilaterally end the agreement on April 3, 2025. Renovaro Inc. (NASDAQ:RENB) is seeking damages, injunctive relief, and specific performance. The case focuses on a Letter Agreement that caused POAI's share price to rise by more than 50% and was made public in a January 6, 2025, Form 8-K. Renovaro Inc. (NASDAQ:RENB) asserts that POAI's activities, which breached the agreed-upon confidentiality and did not participate in substantive negotiations toward a final agreement, violated the conditions of the merger. Renovaro Inc. (NASDAQ:RENB) is a TechBio business that specializes in cancer treatments, drug development, and diagnostics. Among its subsidiaries are BioSymetrics (AI for precision neurology), RenovaroBio (cell-gene immunotherapy), and RenovaroCube (AI-driven diagnostics and drug development). Concerns about shareholder value and legal attempts to uphold M&A agreements are brought to light in this case. While we acknowledge the potential of RENB to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than RENB and that has 100x upside potential, check out our report about this READ NEXT: and .
Yahoo
22-05-2025
- Business
- Yahoo
UPDATE - Renovaro Inc. Announces Expedited Trial for 2025 Lawsuit to Enforce Binding Merger Agreement with Predictive Oncology
LOS ANGELES, May 22, 2025 (GLOBE NEWSWIRE) -- Renovaro Inc. (NASDAQ: RENB), a TechBio leader focused on next-generation diagnostics, drug discovery, and genetically enhanced cancer therapies, today announced that it has received a ruling to expedite a trial in 2025 for the lawsuit it filed on May 9, 2025, in the Delaware Court of Chancery against Predictive Oncology Inc. (NASDAQ: POAI), seeking to enforce a binding merger agreement executed on January 1, 2025. According to the Verified Complaint, the companies entered into a legally binding Letter Agreement pursuant to which Predictive Oncology would merge into Renovaro in exchange for a newly created class of preferred stock. Following the public disclosure of the agreement in a Form 8-K filed by POAI on January 6, 2025, POAI's stock price rose by more than 50%. Renovaro alleges that Predictive Oncology breached the agreement's exclusivity and good faith negotiation provisions by conducting a public offering of $545,000 in securities on February 19, 2025—despite contractual restrictions—and later attempting to terminate the agreement unilaterally on April 3, 2025, without engaging meaningfully in the negotiation of a definitive merger agreement. 'This transaction was intended to create strategic and shareholder value for both companies. Unfortunately, Predictive Oncology has disregarded its contractual commitments,' said a Renovaro spokesperson. 'We are pursuing legal remedies to enforce our rights and protect our shareholders' interests.' The litigation seeks specific performance, injunctive relief, and damages for the alleged breaches. The case is pending in the Delaware Court of Chancery under Case No. 2025-0509. About Renovaro Inc. Renovaro aims to accelerate precision and personalized medicine for longevity powered by mutually reinforcing AI and biotechnology platforms for early diagnosis, better-targeted treatments, and drug discovery. Renovaro Inc. includes RenovaroBio with its advanced cell-gene immunotherapy company and RenovaroCube that is leveraging AI for multi-omic diagnostics and drug development, and BioSymetrics which specializes in contingent AI for precision neurology. For more information, visit Forward-Looking Statements This release contains forward-looking statements, including those relating to the pending litigation and the proposed merger. These statements involve risks and uncertainties and are subject to change based on future developments. Renovaro undertakes no obligation to update any forward-looking statements except as required by law. Investor Relations Chris TysonExecutive Vice PresidentMZ Group - MZ North America949-491-8235RENB@ For media inquiries, please contact: karen@ in to access your portfolio
Yahoo
22-05-2025
- Business
- Yahoo
Renovaro Inc. Announces Expedited Trail for 2025 Lawsuit to Enforce Binding Merger Agreement with Predictive Oncology
LOS ANGELES, May 22, 2025 (GLOBE NEWSWIRE) -- Renovaro Inc. (NASDAQ: RENB), a TechBio leader focused on next-generation diagnostics, drug discovery, and genetically enhanced cancer therapies, today announced that it has received a ruling to expedite a trial in 2025 for the lawsuit it filed on May 9, 2025, in the Delaware Court of Chancery against Predictive Oncology Inc. (NASDAQ: POAI), seeking to enforce a binding merger agreement executed on January 1, 2025. According to the Verified Complaint, the companies entered into a legally binding Letter Agreement pursuant to which Predictive Oncology would merge into Renovaro in exchange for a newly created class of preferred stock. Following the public disclosure of the agreement in a Form 8-K filed by POAI on January 6, 2025, POAI's stock price rose by more than 50%. Renovaro alleges that Predictive Oncology breached the agreement's exclusivity and good faith negotiation provisions by conducting a public offering of $545,000 in securities on February 19, 2025—despite contractual restrictions—and later attempting to terminate the agreement unilaterally on April 3, 2025, without engaging meaningfully in the negotiation of a definitive merger agreement. 'This transaction was intended to create strategic and shareholder value for both companies. Unfortunately, Predictive Oncology has disregarded its contractual commitments,' said a Renovaro spokesperson. 'We are pursuing legal remedies to enforce our rights and protect our shareholders' interests.' The litigation seeks specific performance, injunctive relief, and damages for the alleged breaches. The case is pending in the Delaware Court of Chancery under Case No. 2025-0509. About Renovaro Inc. Renovaro aims to accelerate precision and personalized medicine for longevity powered by mutually reinforcing AI and biotechnology platforms for early diagnosis, better-targeted treatments, and drug discovery. Renovaro Inc. includes RenovaroBio with its advanced cell-gene immunotherapy company and RenovaroCube that is leveraging AI for multi-omic diagnostics and drug development, and BioSymetrics which specializes in contingent AI for precision neurology. For more information, visit Forward-Looking Statements This release contains forward-looking statements, including those relating to the pending litigation and the proposed merger. These statements involve risks and uncertainties and are subject to change based on future developments. Renovaro undertakes no obligation to update any forward-looking statements except as required by law. Investor Relations Chris TysonExecutive Vice PresidentMZ Group - MZ North America949-491-8235RENB@ For media inquiries, please contact: karen@ in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
