Latest news with #PsO
Yahoo
10-07-2025
- Health
- Yahoo
Novartis and the pan-Canadian Pharmaceutical Alliance achieve milestone agreement on Cosentyx® for hidradenitis suppurativa (HS)
Important milestone towards public reimbursement for a new treatment option for eligible Canadian patients living with moderate to severe hidradenitis suppurativa (HS) Following this important milestone, Cosentyx has been listed in Québec MONTRÉAL, July 10, 2025 /CNW/ - Novartis Pharmaceuticals Canada Inc. (Novartis) is pleased to announce the successful conclusion of negotiations with the pan-Canadian Pharmaceutical Alliance (pCPA) on the public reimbursement of Cosentyx (secukinumab) for the treatment of adults with moderate to severe hidradenitis suppurativa (HS), a chronic, painful and often debilitating inflammatory skin condition.1 Following the completion of these negotiations, Cosentyx has been listed in Québec, making it the first province to provide public reimbursement for Cosentyx in HS. Novartis remains committed to ongoing collaboration with provincial public drug programs across Canada to enable timely access and reimbursement for eligible patients nationwide. "Too often, people living with HS feel like their condition is invisible within the healthcare system," said Latoya Palmer, Founder of Hidradenitis and Me Support Group. "As someone living with HS, it gives me hope to see this step forward. It feels validating and shows people like me that there is a path toward better support for those who need it most." "For people living with moderate to severe HS, the condition can have a profound impact on daily life - not only due to physical symptoms, but also the emotional toll it can take," said Dr. Susan Poelman, Canadian and U.S. Board-Certified Dermatologist. "The conclusion of pCPA negotiations for Cosentyx is a promising step that could help expand possibilities for patients who have historically had limited treatment options." "Concluding pCPA negotiations for Cosentyx in HS is an important step toward improving access to a therapy grounded in strong science and real patient need," said Mark Vineis, Country President, Novartis Pharmaceuticals Canada Inc. "At Novartis, we are committed to continuing to work with stakeholders across the healthcare system to help ensure eligible patients with HS have timely public access to innovative treatment options." About Cosentyx® (secukinumab) Cosentyx is the first and only fully human biologic that directly inhibits interleukin-17A, an important cytokine involved in many inflammatory diseases.2,3 Cosentyx is a proven medicine and has been studied clinically for more than 14 years. The medicine is backed by robust evidence, including 5 years of clinical data in adults supporting long-term safety and efficacy across moderate to severe plaque psoriasis (PsO), Axial spondyloarthritis (axSpA) and juvenile idiopathic arthritis (JIA).4,5,6,7,8,9 These data strengthen the position of Cosentyx as a treatment across moderate to severe PsO (adult and pediatric), PsA, HS, axial spondyloarthritis (axSpA), and juvenile idiopathic arthritis (JIA), including enthesitis-related arthritis and juvenile PsA. More than 1 million patients have been treated with Cosentyx worldwide since its launch in 2015. About Novartis Novartis is a focused innovative medicines company. Every day, we work to reimagine medicine to improve and extend people's lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach more than 300 million people worldwide. Reimagine medicine with us. In Canada, Novartis Pharmaceuticals Canada Inc. employs approximately 600 people to serve the evolving needs of patients and the healthcare system and invests over $30 million in R&D yearly in the country. For more information visit FA-11466794E_________________________________1 Novartis Europharm Limited. Cosentyx® (secukinumab): Summary of Product Characteristics. Accessed on June 6, 2025. Available at: Girolomoni G, Mrowietz U and Paul C. Psoriasis: rationale for targeting interleukin-17. Br J Dermatol 2012; 167: 717-724. Accessed on June 6, 2025. Available at: Baraliakos X, Braun J, Deodhar A, et al. Long-term efficacy and safety of secukinumab 150 mg in ankylosing spondylitis: 5-year results from the phase III MEASURE 1 extension study. RMD Open 2019; 5: e001005.5 Bissonnette R, Luger T, Thaçi D, et al. Secukinumab demonstrates high sustained efficacy and a favourable safety profile in patients with moderate-to-severe psoriasis through 5 years of treatment (SCULPTURE Extension Study). J Eur Acad Dermatol Venereol 2018; 32: 1507-1514.6 Mease PJ, Kavanaugh A, Reimold A, et al. Secukinumab Provides Sustained Improvements in the Signs and Symptoms of Psoriatic Arthritis: Final 5-year Results from the Phase 3 FUTURE 1 Study. ACR Open Rheumatol 2020; 2: 18-25.7 Data on file. CAIN457F2310 (MEASURE 1 and 2): Pooled Safety Data. Novartis Pharmaceuticals Corp; July 23, 2018.8 Data on file. CAIN457F2312 (FUTURE 2): 5 year-interim report. Novartis Pharmaceuticals Corp; May 2019.9 McInnes IB, Mease PJ, Kirkham B, et al. Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 2015; 386: 1137-1146. SOURCE Novartis Pharmaceuticals Canada Inc. 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Cision Canada
10-07-2025
- Health
- Cision Canada
Novartis and the pan-Canadian Pharmaceutical Alliance achieve milestone agreement on Cosentyx® for hidradenitis suppurativa (HS) Français
Important milestone towards public reimbursement for a new treatment option for eligible Canadian patients living with moderate to severe hidradenitis suppurativa (HS) Following this important milestone, Cosentyx has been listed in Québec MONTRÉAL, July 10, 2025 /CNW/ - Novartis Pharmaceuticals Canada Inc. (Novartis) is pleased to announce the successful conclusion of negotiations with the pan-Canadian Pharmaceutical Alliance (pCPA) on the public reimbursement of Cosentyx (secukinumab) for the treatment of adults with moderate to severe hidradenitis suppurativa (HS), a chronic, painful and often debilitating inflammatory skin condition. 1 Following the completion of these negotiations, Cosentyx has been listed in Québec, making it the first province to provide public reimbursement for Cosentyx in HS. Novartis remains committed to ongoing collaboration with provincial public drug programs across Canada to enable timely access and reimbursement for eligible patients nationwide. "Too often, people living with HS feel like their condition is invisible within the healthcare system," said Latoya Palmer, Founder of Hidradenitis and Me Support Group. "As someone living with HS, it gives me hope to see this step forward. It feels validating and shows people like me that there is a path toward better support for those who need it most." "For people living with moderate to severe HS, the condition can have a profound impact on daily life - not only due to physical symptoms, but also the emotional toll it can take," said Dr. Susan Poelman, Canadian and U.S. Board-Certified Dermatologist. "The conclusion of pCPA negotiations for Cosentyx is a promising step that could help expand possibilities for patients who have historically had limited treatment options." "Concluding pCPA negotiations for Cosentyx in HS is an important step toward improving access to a therapy grounded in strong science and real patient need," said Mark Vineis, Country President, Novartis Pharmaceuticals Canada Inc. "At Novartis, we are committed to continuing to work with stakeholders across the healthcare system to help ensure eligible patients with HS have timely public access to innovative treatment options." About Cosentyx ® (secukinumab) Cosentyx is the first and only fully human biologic that directly inhibits interleukin-17A, an important cytokine involved in many inflammatory diseases. 2,3 Cosentyx is a proven medicine and has been studied clinically for more than 14 years. The medicine is backed by robust evidence, including 5 years of clinical data in adults supporting long-term safety and efficacy across moderate to severe plaque psoriasis (PsO), Axial spondyloarthritis (axSpA) and juvenile idiopathic arthritis (JIA). 4,5,6,7,8,9 These data strengthen the position of Cosentyx as a treatment across moderate to severe PsO (adult and pediatric), PsA, HS, axial spondyloarthritis (axSpA), and juvenile idiopathic arthritis (JIA), including enthesitis-related arthritis and juvenile PsA. More than 1 million patients have been treated with Cosentyx worldwide since its launch in 2015. About Novartis Novartis is a focused innovative medicines company. Every day, we work to reimagine medicine to improve and extend people's lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach more than 300 million people worldwide. Reimagine medicine with us. In Canada, Novartis Pharmaceuticals Canada Inc. employs approximately 600 people to serve the evolving needs of patients and the healthcare system and invests over $30 million in R&D yearly in the country. For more information visit FA-11466794E SOURCE Novartis Pharmaceuticals Canada Inc.
Medscape
12-06-2025
- Health
- Medscape
US Bursitis and BMI Predict Joint Issues in Psoriasis
In patients with mild psoriasis and no initial musculoskeletal signs, ultrasound bursitis at entheses was associated with the development of inflammatory symptoms suggestive of psoriatic arthritis (PsA), and those who developed musculoskeletal symptoms had higher BMI and fatigue scores and had a higher risk for transition to PsA. METHODOLOGY: This prospective multicentre study included 78 patients with mild psoriasis without musculoskeletal symptoms who were not on systemic treatment; 82% of them had mild disease and 39.7% presented with onychopathy. Researchers performed ultrasound evaluation of 40 joints and 10 entheses bilaterally at baseline and during follow-up; these were assessed for synovial hypertrophy, power Doppler signal, and entheseal changes including bursitis. Study outcomes were the diagnosis of PsA and new-onset musculoskeletal symptoms. The median follow-up duration was 76.6 months. TAKEAWAY: Among 60 patients who completed the study, 6.6% developed PsA over a mean of 20.2 months according to the CASPAR criteria, corresponding to the annual incidence of approximately 1%. Overall, 56.6% of patients developed musculoskeletal symptoms and had significantly higher BMI ( P = .013) and abdominal circumference ( P = .022) at baseline. = .013) and abdominal circumference ( = .022) at baseline. These patients also scored higher on pain (2.14 vs 0.91; P = .047) and fatigue (3.25 vs 1.21; P = .011) components of the baseline Psoriatic Arthritis Impact of Disease questionnaire than those not developed musculoskeletal symptoms. = .047) and fatigue (3.25 vs 1.21; = .011) components of the baseline Psoriatic Arthritis Impact of Disease questionnaire than those not developed musculoskeletal symptoms. Ultrasound bursitis at entheses was present in 80% of patients who developed inflammatory arthralgia suggestive of PsA ( P = .049). = .049). The total joint ultrasound score at baseline was significantly higher in patients who developed musculoskeletal symptoms ( P = .037). IN PRACTICE: "Around half of the patients with PsO [psoriasis] developed MSK [musculoskeletal] symptoms during the follow-up and they had significantly higher BMI, more joint US [ultrasound] findings and scored higher in pain and fatigue scales at baseline PsAID [Psoriatic Arthritis Impact of Disease] questionnaire, defining a subgroup with potentially higher risk to develop PsA. On the other hand, US bursitis at enthesis was related to the onset of MSK symptoms suggestive of PsA," the authors wrote. SOURCE: This study was led by Ana Belén Azuaga, Hospital Clinic, Barcelona, Spain. It was published online on June 04, 2025, in Rheumatology . LIMITATIONS: The sample size was relatively small, potentially underestimating the incidence of PsA in patients with psoriasis. The exclusion of patients with musculoskeletal symptoms and those on systemic therapy likely excluded individuals with a higher risk of developing PsA. Additionally, a significant proportion of patients initiated disease-modifying antirheumatic drug therapy during the study, including biologics, which could have affected the development of PsA symptoms. DISCLOSURES: This study was supported by research grants from Pfizer and Novartis. Additional support came from the Innovative Medicines Initiative 2 Joint Undertaking. The authors declared having no conflicts of interest.
Yahoo
12-05-2025
- Health
- Yahoo
J&J reports new data from Phase III trial of icotrokinra for plaque psoriasis
Johnson & Johnson (J&J) has reported new data from the Phase III ICONIC-TOTAL trial, which evaluated icotrokinra, an oral peptide, in treating plaque psoriasis (PsO). The randomised clinical trial focused on the adult and adolescent patients aged 12 and above, having a body surface area as low as 1% and with at least moderate psoriasis affecting critical skin sites. The study is designed to assess the safety and efficacy of the therapy against placebo for treating plaque PsO in 311 subjects who have at least moderate severity affecting areas such as scalp, genital and/or hands and feet), with overall Investigator's Global Assessment (IGA) score of 0 or 1 with a minimum of a two-grade improvement as the primary goal. The primary endpoint was met, with 57% of subjects treated with the therapy achieving clear or almost clear skin at the mark of week 16 based on the IGA score, against the 6% in the placebo group. J&J noted that the therapy also showed high skin clearance rates in subjects having scalp and genital psoriasis, with 66% and 77% of patients, respectively, achieving clear or almost clear skin, compared to 11% and 21% with placebo. In a smaller subset of subjects having hand/foot psoriasis, the therapy's treatment demonstrated a numerically higher rate of skin clearance, with 42% achieving a hand and/or foot Physician's Global Assessment (hf-PGA)score of clear (0) or almost clear skin (1) against 26% for placebo. The safety profile of the therapy was found to be favourable, without any safety signals observed. Johnson & Johnson Innovative Medicine vice-president and immunodermatology disease area lead Liza O'Dowd said: 'These new findings build upon the impressive scalp psoriasis results seen in ICONIC-LEAD and strengthen the breadth of data demonstrating the potential for icotrokinra to shift the treatment paradigm in moderate-to-severe plaque psoriasis, by offering a combination of skin clearance and favourable safety in a once daily pill.' This study is part of the larger ICONIC clinical development programme, which began in the fourth quarter of 2023 with two trials, ICONIC-LEAD and ICONIC-TOTAL, under a licence and partnership agreement between J&J's Janssen Biotech and Protagonist Therapeutics. Plaque PsO is stated to be a chronic immune-mediated condition leading to painful, inflamed, scaly plaques on the skin. Also known as JNJ-77242113 or JNJ-2113, icotrokinra is tailored to selectively block the Interleukin-23 (IL-23) receptor, which is a key player in the inflammatory response associated with plaque PsO, ulcerative colitis, and other IL-23-mediated conditions. Last month, Johnson & Johnson reported data from the ICONIC-LEAD trial's subgroup analysis, assessing icotrokinra in treating moderate-to-severe plaque PsO. "J&J reports new data from Phase III trial of icotrokinra for plaque psoriasis" was originally created and published by Clinical Trials Arena, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
12-03-2025
- Business
- Yahoo
STEQEYMA® (ustekinumab-stba), a biosimilar to STELARA® (ustekinumab), now available in the United States
STEQEYMA®, one of the first-wave biosimilars to STELARA®, is now available in the U.S. Approved for the same indications as the reference product, STEQEYMA will be priced with a wholesale acquisition cost (WAC) list price at an 85% discount to the current WAC list price of STELARA to help improve patient access to high-quality biologic treatments[1] With the launch of STEQEYMA, Celltrion expands its immunology portfolio beyond tumor necrosis factor (TNF)-alpha inhibitors, to include interleukin (IL)-12 and IL-23 inhibitors, broadening treatment options for multiple immune-mediated diseases Celltrion has nine biosimilars and five immunology biologics granted marketing authorization in the U.S. JERSEY CITY, N.J., March 12, 2025 /PRNewswire/ -- Celltrion today announced the U.S. launch of STEQEYMA® (ustekinumab-stba), a biosimilar to STELARA® (ustekinumab), following approval by the U.S. Food and Drug Administration (FDA) in December 2024. STEQEYMA is approved for the same indications as STELARA, providing consistency in treatment for patients and healthcare providers.[1] STEQEYMA is indicated for the treatment of plaque psoriasis (PsO) and psoriatic arthritis (PsA) in adult and pediatric patients, as well as Crohn's disease (CD) and ulcerative colitis (UC) in adult patients. It is available in both subcutaneous injection and intravenous infusion.[1] "Chronic inflammatory diseases such as plaque psoriasis and psoriatic arthritis place significant burden on patients," said Mark G. Lebwohl*, MD, Icahn School of Medicine at Mount Sinai, New York. "Biosimilars increase access to essential therapies, while maintaining the same high standards as the reference product. The availability of STEQEYMA provides patients and healthcare providers a cost-effective alternative to manage chronic inflammatory diseases." STEQEYMA will be priced with a WAC list price at an 85% discount to the current WAC list price of STELARA to help improve patient access to high-quality biologic treatments. The FDA approval of STEQEYMA was based on the totality of evidence, including the results from a Phase III study in adults with moderate to severe plaque psoriasis, in which the primary endpoint was the rate of change in the Psoriasis Area and Severity Index (PASI) for skin symptoms. The clinical results demonstrated that STEQEYMA and its reference product, ustekinumab, are highly similar, and have no clinically meaningful differences in terms of safety and efficacy. [2],[3] "The introduction of STEQEYMA in the U.S., as one of the first-wave biosimilars to STELARA, marks an important step in our ongoing efforts to expand patient access to high-quality biologic treatments," said Thomas Nusbickel, Chief Commercial Officer at Celltrion USA. "With this launch, we are expanding our immunology portfolio beyond TNF-alpha to include IL-12/23 inhibitors, offering more options for multiple immune-mediated diseases. To further enhance accessibility, Celltrion is actively collaborating with key pharmacy benefit managers to secure broader formulary coverage for STEQEYMA." STEQEYMA is supported by Celltrion's comprehensive patient and practice support programs, designed to assist patients throughout their treatment journey. Celltrion offers a suite of resources, including Celltrion CONNECT® Patient Support Program and Celltrion CARES™ Co-pay Assistance Program, benefits verification, prior authorization assistance, and co-pay assistance. Eligible patients with private or commercial insurance may pay as little as $0 out of pocket per dose. Patients who are uninsured may be eligible to receive STEQEYMA through the Celltrion CONNECT® Patient Assistance Program (PAP). Additionally, nurses will be available to answer patient questions and provide injection support. Visit to learn more. Celltrion has nine biosimilars approved by the FDA, demonstrating its established leadership in the biosimilar development space and its commitment to advancing high-quality treatments. STEQEYMA has also received approval in key global markets, including the European Union, Canada and Australia. Notes to Editors: *Dr. Mark Lebwohl is a paid consultant for Celltrion. About STEQEYMA® (ustekinumab-stba) STEQEYMA®, formerly known as CT-P43, is a human IL-12 and -23 antagonist indicated for multiple immune-mediated diseases. It encompasses all indications approved for the STELARA® reference product, including psoriasis (PsO), psoriatic arthritis (PsA), Crohn's disease (CD), ulcerative colitis (UC) in adults, and PsO and PsA in pediatric patients 6 years of age and older. STEQEYMA is available in both subcutaneous and intravenous formulations. The subcutaneous injection comes in two strengths: 45mg/0.5 mL or 90mg/1 mL solution in a single-dose, prefilled syringe. The intravenous infusion is provided as a 130mg/26 mL (5mg/mL) solution in a single-dose vial. INDICATIONS STEQEYMA® (ustekinumab-stba) is indicated for the treatment of: Plaque Psoriasis (PsO) in adults and pediatric patients 6 years of age and older with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy. Psoriatic Arthritis (PsA) in adults and pediatric patients 6 years of age and older with active psoriatic arthritis. Crohn's Disease (CD) in adult patients with moderately to severely active Crohn's disease. Ulcerative Colitis (UC) in adult patients with moderately to severely active ulcerative colitis. IMPORTANT SAFETY INFORMATION STEQEYMA is contraindicated in patients with clinically significant hypersensitivity to ustekinumab products or to any of the excipients in STEQEYMA. Serious infections have occurred. Avoid starting STEQEYMA during any clinically important active infection. If a serious or clinically significant infection develop, discontinue STEQEYMA until the infection resolves. Serious infections from mycobacteria, salmonella, and BCG vaccinations have been reported in patients genetically deficient in IL-12/IL-23. Consider diagnostic tests for these infections as dictated by clinical circumstances. Evaluate patients for TB prior to starting STEQEYMA. Initiate treatment of latent TB before administering STEQEYMA. Ustekinumab products may increase risk of malignancy. The safety of ustekinumab products in patients with a history of or a known malignancy has not been evaluated. Monitor all patients receiving STEQEYMA for signs of malignancies. If an anaphylactic or other clinically significant hypersensitivity reaction occurs, institute appropriate therapy and discontinue STEQEYMA. If Posterior Reversible Encephalopathy Syndrome (PRES) is suspected, treat promptly, and discontinue STEQEYMA. Avoid use of live vaccines in patients during treatment with STEQEYMA. Non-live vaccinations received during STEQEYMA treatment may not elicit enough immune response to prevent disease. If diagnosis of noninfectious pneumonia is confirmed, discontinue STEQEYMA and institute appropriate treatment. The most common adverse reactions (≥3%) reported in patients receiving ustekinumab were: Psoriasis: nasopharyngitis, upper respiratory tract infection, headache, and fatigue. CD: vomiting, nasopharyngitis, injection site erythema, vulvovaginal candidiasis/mycotic infection, bronchitis, pruritus, urinary tract infection, and sinusitis. UC: nasopharyngitis, nasopharyngitis, headache, abdominal pain, influenza, fever, diarrhea, sinusitis, fatigue, and nausea. For more information, see Full Prescribing Information. About Celltrion Celltrion is a leading biopharmaceutical company that specializes in researching, developing, manufacturing, marketing and sales of innovative therapeutics that improve people's lives worldwide. Celltrion is a pioneer in the biosimilar space, having launched the world's first monoclonal antibody biosimilar. Our global pharmaceutical portfolio addresses a range of therapeutic areas including immunology, oncology, hematology, ophthalmology and endocrinology. Beyond biosimilar products, we are committed to advancing our pipeline with novel drugs to push the boundaries of scientific innovation and deliver quality medicines. For more information, please visit our website and stay updated with our latest news and events on our social media: LinkedIn, Instagram, X, and Facebook. About Celltrion USA Celltrion USA is Celltrion's U.S. subsidiary established in 2018. Headquartered in New Jersey, Celltrion USA is committed to expanding access to innovative biologics to improve care for U.S. patients. Celltrion currently has nine biosimilars approved by the U.S. FDA: INFLECTRA® (infliximab-dyyb), TRUXIMA® (rituximab-abbs), HERZUMA® (trastuzumab-pkrb), VEGZELMA® (bevacizumab-adcd), YUFLYMA®(adalimumab-aaty), STEQEYMA® (ustekinumab-stba), AVTOZMA® (tocilizumab-anoh), OSENVELT®/ STOBOCLO® (denosumab-bmwo), and OMLYCLO® (omalizumab-igec), as well as a novel biologic ZYMFENTRA® (infliximab-dyyb). Celltrion USA will continue to leverage Celltrion's unique heritage in biotechnology, supply chain excellence and best-in-class sales capabilities to improve access to high-quality biopharmaceuticals for U.S. patients. For more information, please visit and stay updated with our latest news and events on our social media: LinkedIn. FORWARD-LOOKING STATEMENT Certain information set forth in this press release contains statements related to our future business and financial performance and future events or developments involving Celltrion, Inc. and its subsidiaries that may constitute forward-looking statements, under pertinent securities laws. This press release contains forward looking statements. These statements may be also identified by words such as "prepares," "hopes to," "upcoming," "plans to," "aims to," "to be launched," "is preparing," "once gained," "could," "with the aim of," "may," "once identified," "will," "working towards," "is due," "become available," "has potential to," the negative of these words or such other variations thereon or comparable terminology. In addition, our representatives may make oral forward-looking statements. Such statements are based on the current expectations and certain assumptions of Celltrion, Inc. and its subsidiaries' management, of which many are beyond its control. Forward-looking statements are provided to allow potential investors the opportunity to understand management's beliefs and opinions in respect of the future so that they may use such beliefs and opinions as one factor in evaluating an investment. These statements are not guarantees of future performance and undue reliance should not be placed on them. Such forward-looking statements necessarily involve known and unknown risks and uncertainties associated with the company's business, including the risk factors disclosed in its Annual Report and/or Quarterly Reports, which may cause actual performance and financial results in future periods to differ materially from any projections of future performance or results expressed or implied by such statements. Celltrion, Inc. and its subsidiaries undertake no obligation to update forward-looking statements if circumstances or management's estimates or opinions should change except as required by applicable securities laws. Trademarks STELARA® is a registered trademark of Johnson & is a registered trademark of Celltrion, Inc., used under license. References [1] STEQEYMA U.S. prescribing information (2024) [2] Papp KA et al., Efficacy and Safety of Candidate Biosimilar CT-P43 Versus Originator Ustekinumab in Moderate to Severe Plaque Psoriasis: 28-Week Results of a Randomised, Active-Controlled, Double-Blind, Phase III study. BioDrugs. 2023; Online ahead of print. Available at: [Last accessed February 2025] [3] Papp K et al., Efficacy and Safety after Switch from Reference Ustekinumab to Ustekinumab Biosimilar (CT-P43) in comparison with the Maintenance Group (CTP43 or Reference Ustekinumab) in Patients with Moderate-to-Severe Plaque Psoriasis: 1-Year Result. [EADV 2023, Abstract #4035]. Available at: [Last accessed February 2025] For further information please contact: Andria Arenaaarena@ 516-578-0057 View original content to download multimedia: SOURCE Celltrion Sign in to access your portfolio
