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What Happens To Your Body When You Stop Taking Drugs Like Ozempic? Study Explains
What Happens To Your Body When You Stop Taking Drugs Like Ozempic? Study Explains

NDTV

time3 days ago

  • Health
  • NDTV

What Happens To Your Body When You Stop Taking Drugs Like Ozempic? Study Explains

A new study has shown that patients who stop taking anti-obesity medications (AOMs) like Ozempic tend to regain the weight they lost, Science Alert reported. A study by Peking University researchers analysed 11 previous trials involving 2,466 participants to evaluate the effectiveness of anti-obesity medications (AOMs). The study included glucagon-like peptide-1 receptor agonists (GLP-1 drugs) like Ozempic and Wegovy, which work by mimicking a natural hormone that regulates appetite and blood sugar. The researchers found that while AOMs were effective in helping participants lose weight during treatment, the weight tended to come back once the course of the drugs was stopped. "Significant weight regain occurred eight weeks after discontinuation of AOMs and was sustained through 20 weeks. Different weight regain was observed in subjects with different characteristics," author Han Wu said. The study found that GLP-1 medications, in particular, showed significant weight regain after treatment discontinuation. Participants who used these medications regained an average of 2.5 kilograms (5.5 pounds) approximately 20 weeks after stopping treatment. Notably, the research also revealed a pattern where individuals who lost more weight during treatment tended to regain more weight afterwards, suggesting that the amount of weight lost is a predictor of subsequent weight regain. To isolate the effects of stopping anti-obesity medications, researchers controlled for factors like exercise levels and diabetes status. However, the underlying reasons for weight regain after treatment stoppage remain unclear. Future studies may investigate these mechanisms further, but weight loss may alter the body's physiology in ways that make maintaining a healthy weight more challenging. This potential "rewiring" of the body could contribute to the difficulty in sustaining weight loss after stopping treatment. Weight regain after treatment isn't just unique to weight-loss medications. It's also been observed with surgical treatments like gastric bypasses and vertical banded gastroplasty. Rise Of Ozempic Ozempic, a drug developed by Novo Nordisk, was approved in 2017 for type 2 diabetes management but has surged in popularity for its weight-loss side effects. Its active ingredient, semaglutide, enhances insulin production, slows digestion, and suppresses appetite, leading to significant weight loss. Its off-label use for obesity, amplified by social media and celebrity endorsements like Elon Musk and Oprah, transformed it into a cultural phenomenon, generating $21 billion in 2023 sales. The demand for Ozempic has surged, leading to shortages and increased costs. Side effects like nausea, muscle loss, and severe gastrointestinal issues affect some users, with weight often returning post-treatment.

This Athleta sale is so good, I already added these 10 deals to my cart
This Athleta sale is so good, I already added these 10 deals to my cart

CNN

time5 days ago

  • Lifestyle
  • CNN

This Athleta sale is so good, I already added these 10 deals to my cart

If you've been hitting the tennis courts or ditching the treadmill to clock outdoor steps this summer, the Athleta Endless Summer Sale has arrived in record time to fuel your active lifestyle. This limited-time sale runs through August 3, taking 25% off at checkout. I got a taste of the deals when I took my mom to the in-person retail store for her birthday. Armed with gift cards, we dove into the racks, finding everything from the best leggings to stylish athleisure wear. Now, with athleisure deals live online, it's the perfect excuse to stock up on the workout clothing pieces you'll wear all season long. Athleta Paradise Mid Rise Wide Leg Pants I'm adding these linen pants to my cart, stat. When I visited the Athleta store in person, they were out of my size, but I loved the weight and opacity of the pair. Now that it's in stock online and tagged with an extra 25% off at checkout, I can't help but commit to the spend. Athleta Crosscourt High-Rise Skort My summer itinerary has featured tennis nearly every other weekend, and it's a bit blasphemous to hit the court without an exercise skirt. This one from Athleta gives you unrestricted mobility, and its built-in shorts not only provide coverage but leave a place to hold spare tennis balls. Athleta Transcend Square Neck Crop Sports Bra Soft and stretchy to the touch, this Transcend sports bra tank feels comfortable during mat pilates and yoga classes. As someone with a bigger bust who struggles to find tops that strike a balance between support and comfort, I appreciate this tank's molded cup options. Athleta Interval Stash High-Rise Shorts Every color of these biker shorts is discounted at Athleta. Starting from $14, you can swipe multiple pairs during this sale. It features a compressive high-rise waistband and side pockets to provide great functionality on the go. Athleta Vital Built-In Bra Tank Combining both a sports bra and a workout tank in one, this Vital top is everything you need to move through yoga flows. It offers a figure-skimming fit with removable pads for customizable coverage. Athleta Signature Rib Tank After a long workout, freshen up with a shower, then go right into comfy mode with this soft, stretchy tank. It also comes in striped options for a more elevated look. The tencel, modal and spandex fabric combination helps keep it breathable. Athleta Weekender Mid Rise 3-Inch Run Shorts Speed through runs with these 3-inch inseam shorts with a secure cinch drawcord and built-in brief. It also features hidden zip pockets to keep your keys and essentials safely stowed without getting in the way. Athleta Renew Seamless Muscle Tank Great for transitioning from workouts to errands, this muscle tank adopts a snug, cropped style that styles easily with everything from linen pants to yoga leggings. Choose from six on-sale colors, starting at just $27. Athleta Elation Ultra High Rise 7/8 Leggings I'm elated — pun, intended — to find these bestselling Athleta leggings discounted in 13 different colors. They span sizes XXS to 3X as well as regular, tall and petite lengths, so you can find the perfect size for you. Athleta Apero Mesh Tee Choose from a chic Cream, Brown or Black mesh tee design. I'm tempted to snag this white hue and style it similarly, with a matching white square-neck sports bra underneath. No doubt, it'll keep your summer days more breathable. This sale brings sweeping savings of 25% off, which stacks atop select sale styles. Athleta consistently tops the competition in our product guides. Our team of testing editors evaluates nearly everything under the fitness umbrella, which means putting clothing to the test in real life with real testers. Specifically with leggings, Athleta performed leaps and bounds ahead of the competition during our tests, holding up against repeat wash cycles without noticeable pilling, fading or stretching. We consider its high quality well worth the investment. Athleta also makes tons of editor favorites, like its sports bras. Our savvy deals team, including senior editor Rikka Altland, deals editor Jacqueline Saguin and associate editor Elena Matarazzo, rakes the internet for hours to find the best deals for readers. That includes checking price history to ensure you're getting a good bargain and keeping tabs on coveted products for when they go on sale at a moment's notice. As someone who has covered fashion deals and product reviews for more than four years, Saguin curated this list of Athleta deals with hits that are both editor-loved items and those with impressive discounts.

Manar is making its way back to Abu Dhabi and it's going to be beautiful
Manar is making its way back to Abu Dhabi and it's going to be beautiful

Time Out Abu Dhabi

time6 days ago

  • Entertainment
  • Time Out Abu Dhabi

Manar is making its way back to Abu Dhabi and it's going to be beautiful

The capital's coasts, islands and skyline are about to glow once again. Manar Abu Dhabi, the city's stunning light art exhibition, is making its much-anticipated return this November and it's bringing even more magic to the waterfront. Launched by the Department of Culture and Tourism – Abu Dhabi (DCT Abu Dhabi) as part of the Public Art Abu Dhabi programme, Manar (which means 'lighthouse' in Arabic) is anything but your typical art show. Think massive light sculptures, ethereal projections, interactive installations and thought-provoking performances – all set against the natural beauty of the capital's shores. Rise 2023 © Alaa Edris Following its dazzling debut in 2023, Manar 2.0 is upping the ante with over 35 artworks from global artists, including powerhouses like teamLab, Carsten Höller and Shezad Dawood, plus homegrown talents like Ahmed Al Areef Al Dhaheri and Nujoom Alghanem. From Japan to Mexico and everywhere in between, it's a lineup that promises to transform Abu Dhabi into a living, glowing canvas. Expect to see light installations ripple across iconic locations like Saadiyat, Jubail and Fahid Island, as well as along the Corniche and Eastern Mangroves. Whether you're walking the coastline, cruising past in a dhow, or snapping pics from dry land, the experience is designed to stop you in your tracks and get you thinking – about nature, about connection and about creativity in all its forms. Stay tuned for the full programme reveal, but for now, mark your calendar. November is going to shine. Summer in Abu Dhabi The 27 best things to do indoors this summer in Abu Dhabi It's time for some air-conditioned bliss Psst: This is when summer officially ends in Abu Dhabi No complaints here 25 brilliant beach and pool day passes in Abu Dhabi Grab your SPF – a lush day by the water awaits

Shade at Siya? Rachel Kolisi posts about 'loyalty'
Shade at Siya? Rachel Kolisi posts about 'loyalty'

The South African

time20-07-2025

  • Entertainment
  • The South African

Shade at Siya? Rachel Kolisi posts about 'loyalty'

Rachel Kolisi has shared another cryptic quote, seemingly about her marriage split from Springbok captain Siya Kolisi. Last October, the mother-of-two announced her separation and has been navigating life as a single parent ever since. Rachel has been accused of 'milking public sympathy' with her social media posts ranging from her anxiety attacks to her driving a 'humble' Toyota Yaris. In an Instagram Story, Rachel Kolisi shared another cryptic post on her Instagram Story. It read: 'The only people I owe my loyalty to are those who never made me question theirs'. In recent months, Rachel has posted several quotes that her followers believe are related to her relationship status. Image via Instagram: @siyakolisi In February, Rachel Kolisi suggested that she was being stalked by someone she had purposely blocked. Her post read: 'You block someone on everything, and all of a sudden, xajdhjsd stars are watching your story.' Over the festive season, another read: 'Let the kids believe in Santa. You believed in your ex 25 times.' In his 2023 documentary and autobiography, Rise , Siya admitted to having a rocky relationship with Rachel after confessing to excessive partying, heavy drinking, being addicted to porn, and frequenting strip clubs. There was also the impression that Siya had been unfaithful to his wife. While Siya and Rachel Kolisi have sadly gone their separate ways a year ago, they were still very much in love. Amid the July Springbok test series, Siya posted a collage of images that included his then-wife Rachel and children, as well as fellow players Cheslin Kolbe and Eben Etzebeth and their respective families. In the pics, Rachel and Siya embraced as they smiled for the cameras. Rachel reposted the images, captioning them: 'A Saturday full of my favourite things'. View this post on Instagram A post shared by Rachel Kolisi (@rachelkolisi) Let us know by leaving a comment below, or send a WhatsApp to 060 011 021 1 . Subscribe to The South African website's newsletters and follow us on WhatsApp , Facebook , X, and Bluesky for the latest news.

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