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Iambic Taps Lambda for Increased AI Compute as it Develops the Next Generation of Enchant, a Breakthrough AI Molecular Property Prediction Model for Drug Discovery
Iambic Taps Lambda for Increased AI Compute as it Develops the Next Generation of Enchant, a Breakthrough AI Molecular Property Prediction Model for Drug Discovery

Business Wire

time26-06-2025

  • Business
  • Business Wire

Iambic Taps Lambda for Increased AI Compute as it Develops the Next Generation of Enchant, a Breakthrough AI Molecular Property Prediction Model for Drug Discovery

SAN JOSE, Calif.--(BUSINESS WIRE)--Lambda, the GPU cloud company founded by AI engineers, today announced that Iambic Therapeutics, a clinical-stage life science and technology company developing novel medicines using its AI-driven discovery and development platform, has selected Lambda to provide an NVIDIA HGX B200 cluster to support the training of Enchant, its industry-leading model for molecular property prediction. Iambic's Enchant is a breakthrough multi-modal transformer model for predicting clinical and preclinical endpoints related to the drug discovery and development process. Enchant enables researchers to determine the viability of new drug molecules and make high-confidence predictions where data is most sparse, helping address the critical real-world challenge of understanding how novel drug candidates may affect a patient while still in the earliest stages of discovery. Iambic's recently announced Enchant v2 provides accurate predictions for dozens of biological, physiochemical, pharmacokinetic, metabolic, safety, and other properties essential for clinical success. 'With the release of Enchant v2, we demonstrated both the model's accuracy and scalability and we believe we can rapidly build on these gains through model scale alone,' said Matt Welborn, PhD, Iambic's VP of Machine Learning. 'We are expanding our successful relationship with Lambda to an NVIDIA HGX B200 cluster, which will accelerate this opportunity and the breadth of pre-clinical and clinical endpoints Enchant can predict, increasing the likelihood of a molecules' success in human studies and the efficiency of drug development.' Enchant's high-confidence predictions enable multi-parameter optimization for the design of potentially more effective medicines, program prioritization, and the design of clinical trials for the potentially rapid translation of novel medicines. Iambic researchers also demonstrated that in some cases Enchant can be a better predictor of in vivo drug clearance than in vitro experiments – a key advancement as regulators look for drug developers to broaden their use of in silico testing. Today, Enchant is the leading model in the field based on performance benchmarks across diverse molecular property prediction tasks. 'We're thrilled to deepen our partnership with Iambic, a leader in AI-driven drug discovery,' said Robert Brooks IV, Founding Team and VP, Revenue. 'By leveraging Lambda's 1-Click Clusters for rapid testing and validation, Iambic was able to seamlessly scale to an NVIDIA HGX B200 cluster to accelerate breakthroughs in life sciences.' To learn more about Lambda's cloud offerings for AI training and inference, click here. About Iambic's AI-Driven Discovery Platform The Iambic AI-driven platform was created to address the most challenging design problems in drug discovery, leveraging technology innovations such as Enchant (multimodal transformer model that predicts clinical and preclinical endpoints) and NeuralPLexer (best-in-class predictor of protein and protein-ligand structures). The integration of physics principles into the platform's AI architectures improves data efficiency and allows molecular models to venture widely across the space of possible chemical structures. The platform enables identification of novel chemical modalities for engaging difficult-to-address biological targets, discovery of defined product profiles that optimize therapeutic window, and multiparameter optimization for highly differentiated development candidates. Through close integration of AI-generated molecular designs with automated chemical synthesis and experimental execution, Iambic completes design-make-test cycles on a weekly cadence. About Iambic Therapeutics Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at About Lambda Lambda was founded in 2012 by AI engineers with published research at the top machine learning conferences in the world. Our goal is to become the #1 AI compute platform serving developers across the entire AI development lifecycle. We enable AI engineers to easily, securely and affordably build, test and deploy AI products at scale. Our product portfolio spans from on-prem GPU hardware to hosted GPUs in the cloud. Lambda's mission is to create a world where access to computation is as effortless and ubiquitous as electricity.

NYS bill would require cameras in all areas of prisons as Dems push new laws after inmate deaths
NYS bill would require cameras in all areas of prisons as Dems push new laws after inmate deaths

New York Post

time11-06-2025

  • Politics
  • New York Post

NYS bill would require cameras in all areas of prisons as Dems push new laws after inmate deaths

ALBANY – Democrats in the state legislature released a package of bills late Monday night meant to increase oversight of state prisons after two high profile deaths over the last year. The bill includes proposals that would require cameras in all areas of prisons except showers and cells, require more thorough reporting and investigations of deaths in prisons, and stack an oversight panel with appointees from the legislature. The legislation was introduced with just enough time to bring it up for a vote before the state Senate ends its regularly-scheduled session for the year later this week. Advertisement The package of proposed laws comes after 10 people were charged in connection to the killing of Robert Brooks in Marcy Correction Facility last December. Six were charged with murder. In March, Messiah Nantwi was killed at neighboring Mid-State correctional facility, leading to murder and other charges for 10 guards in that case. 10 people have been charged, including some with murder, in the brutal beating of Robert Brooks at Marcy Correctional Facility. New York State Department of Corrections via the New York State Attorney General's Office/AFP via Getty Images 'It is without question that Robert Brooks and Messiah Nantwi should both be alive today,' Assemblywoman Michalle Solages (D-Nassau), Chair of the influential Black, Puerto Rican, Hispanic and Asian Caucus, wrote in a recent statement. 'Their lives were cut short by a system that has repeatedly failed Black and brown communities, a system that strips individuals of their agency and denies them the right to safety, justice, and redemption. Advertisement 'New York State must take decisive action this session to end this cycle of harm, because accountability and justice cannot wait,' Solages continued. The legislation includes provisions from separate bills penned by a number of legislators. The package as a whole is carried by each chambers' corrections committee chair, state Sen. Julia Salazar (D-Brooklyn) and Assemblymember Erik Dilan (D-Brooklyn) The package does not include provisions loosening requirements for parole and some early release programs despite a push by some liberal lawmakers to squeeze them with the other proposals. Gov. Kathy Hochul had floated, then retracted, those provisions during state budget talks earlier this year. Thousands of corrections officers participated in a crippling illegal strike earlier this year. Hans Pennink Advertisement 'While we applaud the legislature's commitment to oversight, oversight is not enough,' Thomas Grant, an organizer at the Center for Community Alternatives, wrote in a statement. 'If lawmakers are serious about honoring Robert Brooks and stopping further death and despair, they must do more than monitor the system—they must offer a fair pathway home for incarcerated people who have transformed while inside.' The state prison system has been in crisis since thousands of corrections officers walked off the job for an illegal wildcat strike earlier this year. Hochul fired 2,000 of them who refused to return to work. National Guard troops are still backfilling during the staff shortfall, costing the state millions of dollars. The package is expected to be voted on in the state Senate before the end of the week.

Catholic Charities disperse across Texoma for a Day of Service
Catholic Charities disperse across Texoma for a Day of Service

Yahoo

time01-06-2025

  • General
  • Yahoo

Catholic Charities disperse across Texoma for a Day of Service

WICHITA FALLS (KFDX/KJTL) — Properties are cleaner, and veterans are enjoying their newly built ramps after this year's Catholic Charities Day of Service. Groups gathered at Vernon College before dispersing around Texoma for various cleanup jobs and building projects. Each year the list of jobs is always different, whether they come from city councilors or other non-profits. Two of the biggest projects of the day were a cleanup of an Eastside property, organized by councilor Robert Brooks, and the construction of a wheelchair ramp at a home in Archer City. Catholic Charities' operations manager, Laura Sotelo, said they find the jobs just about everywhere. 'We always seem like we get requests to build ramps for folks. And so, this year we've been able to partner with a group that does that on a regular basis. And so, they can provide the professional guidance on it, and we can just provide the manpower,' Sotelo said. 'So, it's really whatever the community needs, and we try to step in and do that.' Catholic Charities also held a food drive for the Vernon College Food Pantry, which is in its second year running, among their other projects for the day. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

Eight correction officers are headed to trial, letting jury hear charges related to Marcy prison beating
Eight correction officers are headed to trial, letting jury hear charges related to Marcy prison beating

Yahoo

time19-05-2025

  • Yahoo

Eight correction officers are headed to trial, letting jury hear charges related to Marcy prison beating

UTICA, N.Y. (WSYR-TV) — Eight of ten correction officers accused of beating an inmate at the Marcy Correctional Facility to death will let an Oneida County jury decide their fate, each having rejected the chance to plead guilty immediately and avoid a trial in exchange for a softer sentence. In Oneida County Court on Monday, May 19, two remaining defendants formally turned down plea agreements offered by the special prosecutor's office. The promise had been a sentence of 15-18 years in prison in exchange for admission of guilt to some of the charges. The eight officers still facing charges are headed to a shared trial, unless the judge agrees to any requests from defense attorneys to sever their cases. A trial date has not been scheduled. Conviction of murder by a jury risks each defendant more than 25 years in prison. Two officers have already admitted guilt to their role in the beating of inmate Robert Brooks. On May 5, Christopher Walrath pleaded guilty to manslaughter in exchange for 15 years in prison and dropping the murder charge against him. On May 14, Nicholas Gentile admitted guilt to attempted tampering with physical evidence. Eight correction officers are headed to trial, letting jury hear charges related to Marcy prison beating Second Marcy officer pleads guilty in beating death of Robert Brooks; Three more reject plea deals Three former Marcy correction officers reject plea deal in beating death of Robert Brooks case First officer pleads guilty for role in brutal beating death of inmate at Marcy Correctional Facility 'Wasteful manner': Frustrated judge allows two more weeks for Marcy offers to decide on plea agreements 'There's something going on:' Violent prison culture allowed inmate deaths, governor says Two more officers given more time to consider plea offer made in Marcy prison case Three correction officers charged with beating death of Marcy inmate get more time to consider plea agreement 'Not a… deal:' Attorney defending correction officer isn't impressed with prosecution's plea offer in prison beating case Officers charged with Marcy inmate's murder have two weeks to consider avoiding trial with guilty plea offers Sixth correction officer charged with murder after beating Marcy inmate Six correction officers charged with murder for beating inmate at Marcy Correctional Facility Onondaga County DA plans 'noteworthy development' in case of Marcy inmate homicide Push for NYS prison reform New Yorkers rally for Robert Brooks outside the Onondaga County DA's office Death of Robert Brooks ruled a homicide, Gov. Hochul pushes for arrests Governor defends keeping Marcy prison open despite calls to close facility after inmate's death New bill aims for 'swift justice' in NYS Correctional abuse cases Assemblyman spends night at Marcy Correctional Facility Some NYS lawmakers call for the closure of Marcy Correctional Facility Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

New York prison guard says he cleaned up blood of fatally beaten inmate in plea
New York prison guard says he cleaned up blood of fatally beaten inmate in plea

CNN

time15-05-2025

  • CNN

New York prison guard says he cleaned up blood of fatally beaten inmate in plea

A New York corrections officer admitted in court Wednesday he cleaned up blood from the fatal beating of an inmate that was captured on bodycam videos in an attempt to conceal evidence. Nicholas Gentile pleaded guilty to a misdemeanor charge of attempted tampering with physical evidence in the Dec. 9 beating of Robert Brooks at the Marcy Correctional Facility. Publicly released video of the assault, which shows officers beating Brooks while his hands were cuffed behind his back, sparked condemnation and calls for reforms. Gentile, 36, was among 10 guards indicted in February in connection with Brooks' death. Six officers were charged with second-degree murder. Gentile was indicted on a felony charge of tampering with physical evidence. Under questioning from the judge and a prosecutor, Gentile acknowledged he knew about the assault by fellow guards, cleaned up Brooks' blood and failed to document it. Under a plea agreement, Gentile was sentenced to a one-year conditional discharge, meaning he can avoid prison time if he resigns his job and obeys the law. He also waived his right to appeal. He declined to make a statement in court. One former officer charged with murder in the assault, Christopher Walrath, pleaded guilty to first-degree manslaughter earlier this month. Three other prison workers have reached agreements but had yet to enter those pleas, according to prosecutors. Brooks began serving a 12-year sentence for first-degree assault in 2017 and was transferred Dec. 9 to Marcy, a prison about 180 miles (290 kilometers) northwest of New York City. Special prosecutor William Fitzpatrick has said Brooks was beaten three times that night, the last of which was the fatal attack caught on bodycam footage. Brooks, 43, was declared dead the next day. Fitzpatrick, the Onondaga County district attorney, also is prosecuting guards in the fatal beating of Messiah Nantwi on March 1 at another Marcy lockup, the Mid-State Correctional Facility.

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