Latest news with #SanDiego-based
Cision Canada
16 hours ago
- Business
- Cision Canada
Oncolytics Biotech® Appoints Former Ambrx Executive as Chief Business Officer to Drive Business Development Strategy
SAN DIEGO and CALGARY, Alberta, June 30, 2025 /CNW/ -- Oncolytics Biotech ® Inc. (NASDAQ: ONCY) (TSX: ONC), a leading clinical-stage company specializing in immunotherapy for oncology, today announced the appointment of Andrew Aromando as Chief Business Officer. Mr. Aromando most recently served as Chief Operating Officer at Ambrx Biopharma, where his contributions were instrumental in the $2 billion acquisition of the San Diego-based biotech by Johnson & Johnson. In his role at Oncolytics, Mr. Aromando will be responsible for leading global business development. He will also be directly involved with developing corporate, clinical and regulatory strategies. Among his key priorities will be optimizing the value of the Company's expansive suite of promising clinical data for pelareorep in multiple tumor types, including pancreatic, breast, and anal cancers. "Andrew's experience will be invaluable as we pursue aggressive clinical and business development strategies to maximize the value of pelareorep on an accelerated timeline," said Jared Kelly, Chief Executive Officer of Oncolytics. "He is a proven industry leader with a successful track record of navigating complex transactions and partnerships and an outstanding addition to our executive team." Mr. Aromando added, "I'm thrilled to join Oncolytics at such a pivotal moment in its evolution. With promising data in difficult-to-treat cancers and a compelling body of clinical evidence in over 1,100 patients, I believe the Company is uniquely positioned to deliver meaningful value to patients and other stakeholders in the near term." Mr. Aromando has over 30 years of experience in the life sciences industry. He has served more than 20 years in C-level positions at leading oncology-focused biopharma companies and global service providers. His senior executive roles at these companies were centered on strategic planning, corporate development, portfolio optimization, and product commercialization. He earned his BA from The College of New Jersey and MA from Rutgers University. As a material inducement to Mr. Aromando's appointment as Chief Business Officer, and in accordance with NASDAQ Listing Rule 5635(c)(4), Mr. Aromando has been awarded an initial stock option grant exercisable for 750,000 shares with an exercise price of CAD$0.93, vesting equally over three years with a term of 5 years from the date of grant. The Company also granted Mr. Aromando 500,000 restricted stock units, which vest upon the Company entering into a definitive agreement for certain transactions providing for the acquisition of the Company or the exclusive license of pelareorep. About Oncolytics Biotech Inc. Oncolytics is a clinical-stage biotechnology company developing pelareorep, an intravenously delivered immunotherapeutic agent. Pelareorep has demonstrated promising results in two randomized Phase 2 studies in metastatic breast cancer and Phase 1 and 2 studies in pancreatic cancer. It acts by inducing anti-cancer immune responses and promotes an inflamed tumor phenotype -- turning "cold" tumors "hot" -- through innate and adaptive immune responses to treat a variety of cancers. Pelareorep has demonstrated synergies with multiple approved oncology treatments. Oncolytics is currently conducting and planning combination clinical trials with pelareorep in solid malignancies as it advances towards registrational studies in metastatic breast cancer and pancreatic cancer, both of which have received Fast Track designation from the FDA. For more about Oncolytics, please visit: or follow the company on social media on LinkedIn and on X @ oncolytics. This press release contains forward-looking statements, within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended and forward-looking information under applicable Canadian securities laws (such forward-looking statements and forward-looking information are collectively referred to herein as "forward-looking statements"). Forward-looking statements contained in this press release include statements regarding Oncolytics' belief as to the potential, mechanism of action and benefits of pelareorep as a cancer therapeutic; our plans, objectives and strategies; our focus on advancing pelareorep into registration enabling studies; and other statements related to anticipated developments in Oncolytics' business and technologies. In any forward-looking statement in which Oncolytics expresses an expectation or belief as to future results, such expectations or beliefs are expressed in good faith and are believed to have a reasonable basis, but there can be no assurance that the statement or expectation or belief will be achieved. Such forward-looking statements involve known and unknown risks and uncertainties, which could cause Oncolytics' actual results to differ materially from those in the forward-looking statements. Such risks and uncertainties include, among others, the availability of funds and resources to pursue research and development projects, the efficacy of pelareorep as a cancer treatment, the success and timely completion of clinical studies and trials, Oncolytics' ability to successfully commercialize pelareorep, uncertainties related to the research and development of pharmaceuticals, uncertainties related to the regulatory process and general changes to the economic environment. We may incur expenses or delays relating to events outside of our control, which could have a material adverse impact on our business, operating results and financial condition. Investors should consult Oncolytics' quarterly and annual filings with the Canadian and U.S. securities commissions for additional information on risks and uncertainties relating to the forward-looking statements. Investors are cautioned against placing undue reliance on forward-looking statements. The Company does not undertake any obligation to update these forward-looking statements, except as required by applicable laws. Company Contact Jon Patton Director of IR & Communication [email protected] Investor Relations for Oncolytics Mike Moyer LifeSci Advisors +1-617-308-4306 [email protected] Media Contact for Oncolytics Owen Blaschak LifeSci Communications [email protected] SOURCE Oncolytics Biotech® Inc.
CNBC
2 days ago
- Business
- CNBC
Is the Guild 1% Down mortgage right for you?
One of the largest home loan providers in the U.S., Guild Mortgage originated over 75,000 mortgages in 2024. The San Diego-based fintech company's flexible credit requirements and generous down payment assistance programs are some of the reasons it landed on CNBC Select's lists of the best mortgage companies and best lenders for a small down payment. One great option Guild has for lower-income homebuyers is the 1% Down mortgage. Borrowers who meet income requirements and have a 1% down payment are eligible for an additional 2% from Guild in the form of a non-repayable grant, up to $5,000. Unlike similar programs from competitors, the 1% Down loan is available to both first-time and repeat buyers with no location restrictions. Apply online for rates. Conventional, FHA, VA, USDA, Arrive Home, Zero Down, jumbo, renovation, refinancing, reverse mortgages, home equity loans 10 to 30 years 540 for FHA, VA and USDA loans; 600 for Zero Down; 620 for conventional loans, 680 for jumbo loans. Nontraditional credit options available 0% for USDA, VA, Arrive Home™ or Zero Down; 1% for conventional loans, 3.5% for FHA loans Approved borrowers with a 1% down payment will get another 2% from Guild in the form of a non-repayable grant. That automatically lets them meet the 3% down payment requirement for conventional loans set by Fannie Mae and Freddie Mac. Applicants may also be eligible for a lender-paid temporary buydown, which covers a portion of their interest for a set period, thereby keeping monthly payments lower initially. Although Guild is not licensed to lend in New York, first-time and repeat homebuyers in every other state can qualify. Income: Up to 80% of the area median incomeCredit score: 620 (other credit sources considered)Other requirements: Must be for a single-family home and borrowers must complete a homebuyer education course Guild's 1% Down loan is a great choice for households earning up to 80% of the area median income. Unlike a number of other down payment assistance programs, it's not limited to first-time buyers or low-to-moderate-income (LMI) census tracts. Since Guild considers alternate credit sources (including on-time utility payments), it's also a strong contender if your credit history is thin or you have a nontraditional income source. You should also consider the loan if you're in a hurry: Guild's Homebuyer Express guarantee means you'll close within 17 days or be eligible for a $500 closing cost rebate (not available in Oregon). Guild has a mixed record with customer satisfaction, though: While it received an A+ from the Better Business Bureau and scored above average for customer satisfaction on J.D. Power's 2024 mortgage servicing survey, it scored below average for origination. There are also inherent drawbacks in making a small down payment: If you don't qualify for the 1% Down program, Guild has other loans with down payment assistance: The Zero Down loan combines a 3.5% FHA loan with a forgivable second mortgage, effectively reducing your down payment to zero. Plus, you only need a 600 credit score to get approved. Guild's Arrive Home loan is another zero-down option available to borrowers who earn as much as 160% of the median income in their area. Looking at other lenders, only requires 1% down, while borrowers can be approved for Citibank's HomeRun mortgage and Chase Bank's DreaMaker loan with as little as 3% down. Offers in this section are from affiliate partners and selected based on a combination of engagement, product relevance, compensation, and consistent availability.10-, 15- and 30-year fixed-term conventional loans, 30-year VA and FHA loans, custom mortgages with fixed-rate terms from 8 to 29 years.6200% for VA, 1% for RocketONE+, 3% for conventional, 3.5% for FHA, 10% to 15% for jumbo10 – 30 years6203% for DreaMaker℠ or Standard Agency loan FHA loans: Backed by the Federal Housing Authority, these mortgages only require 3.5% down if you have a 580 credit score or better. USDA loan: The U.S. Department of Agriculture guarantees zero-down home loans to borrowers buying in select rural and suburban areas and earning up to 115% of the AMI. VA loan: These zero-down-payment mortgages, backed by the Department of Veteran Affairs are available to active duty service members, reservists and veterans. HomeReady: You only need a down payment of 3% down with this Fannie Mae-backed mortgage. Borrowers must earn no more than 80% of the area median income and have a credit score of at least 620. Home Possible: You only need a down payment of 3% down with this Freddie Mac-backed mortgage. Borrowers must earn no more than 80% of the area median income and have a credit score of at least 620. Founded in 1960, San Diego-based Guild Mortgage is a legitimate lender with 740 branches in 46 states. It's licensed nationwide except in New York and, in 2024, approved 75,356 mortgages totalling $23.2 billion. Guild Mortgage requires score of 620 for a conventional mortgage, 1% Down and Arrive Home loan and a 600 to qualify for its Zero Down loan. Guild accepts scores of 540 for FHA, VA and USDA mortgages and 680 for jumbo loans, lower than many other lenders. Ranked No. 4 on J.D. Power's 2024 survey of mortgage servicers, Guild Mortgage claims it services the majority of the loans it originates. According to the Guild website, "We're your loan partner throughout the life of the loan." Money matters — so make the most of it. Get expert tips, strategies, news and everything else you need to maximize your money, right to your inbox. Sign up here. At CNBC Select, our mission is to provide our readers with high-quality service journalism and comprehensive consumer advice so they can make informed decisions with their money. Every mortgage review is based on rigorous reporting by our team of expert writers and editors with extensive knowledge of mortgage products. While CNBC Select earns a commission from affiliate partners on many offers and links, we create all our content without input from our commercial team or any outside third parties, and we pride ourselves on our journalistic standards and ethics. CNBC Select reviews mortgage products using a variety of criteria, including average rates, eligibility requirements, available terms, fees, nationwide availability, online experience and customer satisfaction. We also incorporate findings from independent sources, including lender scores from J.D. Power's mortgage origination and servicer surveys and ratings from the Better Business Bureau.
Time Magazine
4 days ago
- Automotive
- Time Magazine
TIME100 Most Influential Companies 2025: Debut
Organic chemist Joshua Britton honed his elevator pitch while driving for Uber as a side hustle. The idea that the beauty industry is moving away from petroleum to a new era of ingredients made in biotech labs persuaded one of his passengers to give him $100,000 in 2019 as Debut Biotech's first angel investor. 'She told me to get out of the Uber and get my ass into the lab,' CEO Britton says. Today San Diego-based Debut not only has its Deinde line of fossil-fuel-free skincare products, but also a partnership with L'Oreal to replace more than a dozen conventionally sourced ingredients used across the cosmetics giant's product portfolio with its own 'bio identical ingredients.' One example unveiled in February 2025: a synthetic vegan replica of carmine, a red pigment normally derived from beetles and used in various cosmetic products. Creating raw materials in the lab instead of extracting the planet's resources has other applications, too. Debut was awarded $2 million from the U.S. Department of Defense in July 2024 to create plans for a domestic biomanufacturing production facility to reduce the country's reliance on foreign sources of vital chemicals.
Yahoo
6 days ago
- Business
- Yahoo
Beyond Ordinary Issues Call for Speakers for PromptCon.AI 2025, a Virtual Conference on the Power and Ethics of Applied AI
San Diego, California--(Newsfile Corp. - June 24, 2025) - Beyond Ordinary Software Solutions, a San Diego-based software and research consultancy known for its work in cybersecurity and AI systems, today announced its official call for speakers for 2025, a virtual conference focused on the evolving role of large language models (LLMs), and artificial intelligence across sectors. The event will take place November 4-6, 2025, and will feature over 30 curated sessions exploring practical applications, technical innovation, and societal impact. Speaker proposals are being accepted through September 15, with 40 open presentation slots available. Practitioners, technologists, researchers, strategic thinkers, and thought leaders are encouraged to propose their talks. Caption: Jacob Anderson, Founder of Beyond Ordinary and To view an enhanced version of this graphic, please visit: "PromptCon is designed for people doing the real work-shipping tools, testing boundaries, or asking the right questions," said Jacob Anderson, founder and CEO of Beyond Ordinary. "We're looking for speakers who want to move the conversation forward-whether that's helping others build smarter infrastructure or examining the ethics of how these systems impact labor, learning, or leadership." The event is structured around three thematic tracks: Applications: Tactical deployment of LLMs and AI in operations, automation, and enterprise workflows Innovation: Explorations of frameworks, performance strategies, and experimental agent design Social Implications: Sessions on misinformation, AI bias, labor displacement, and inclusive development Confirmed speakers include: Andrew Brooks (CEO, on ROI in enterprise AI deployment Kham Inthirath (CEO, Compound Effect) on LLMs as co-pilots in business ops Jared Zoneraich (Founder, PromptLayer) on agent testing strategies Chris Gee (Chris Gee Consulting) on AI's role in reshaping entry-level work Andrew Barrow (Founder, Revenue Arc) on competitive strategy in AI innovation Each day of PromptCon will open with a keynote and close with cross-track conversations tying technical progress to broader ethical, social, and strategic questions. How to Apply: Interested speakers should submit proposals directly to speakers@ no later than September 15. Submissions will be reviewed on a rolling basis, and selected speakers will join a diverse lineup of technologists, executives, researchers, non-technical super-users, and tomorrows AI thought leaders. About Beyond Ordinary Software Solutions Beyond Ordinary is a boutique software firm based in San Diego, specializing in secure, high-performance systems across both federal and commercial sectors. With deep experience supporting the Department of Defense and a growing footprint in applied AI, the firm focuses on cybersecurity, predictive modeling, adaptive UI, and LLM deployment at scale. Learn more at Contact:Jacob Andersonjwa@ To view the source version of this press release, please visit Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Politico
23-06-2025
- Business
- Politico
Los Angeles tourism industry and labor unions brawl ahead of Olympics
LOS ANGELES — For tens of thousands of Angelenos, this month's 'No Kings' protests were a way to peacefully register discontent with the Trump administration. For some in their midst, the protests represented something else entirely: a bonanza of potential signers. The June 14 demonstrations turned into an unexpected battleground for those organizing on both sides of a roiling, pre-Olympic conflict between Los Angeles' formidable travel industry and powerful unions. After the city council passed a $30 minimum wage law in late May for workers in the airline, hotel and hospitality industries, a group of business interests — signed by players in the local hospitality industry and funded by major airlines like Delta, United, Marriott and Hilton — launched a referendum effort to challenge the new law. 'We're giving everything we have to make this business work, to claw out of the hole that was created by COVID,' said Greg Plummer, a referendum proponent who runs a 250-employee concession company at LAX. 'Our airports are still down substantially in traffic. Tourism is completely down, and the fires didn't help … it gets to a point where it's going to crumble a lot of small businesses.' Unions countered with two initiatives of their own last week, one that would increase the citywide minimum wage to $30 per hour for workers across sectors and another that would require voter approval for the construction of large hotels, significant hotel expansions and 'event centers' like sports stadiums. 'Hotels and the airlines are spending millions of dollars to make sure their workers don't get a raise,' said Kurt Petersen, head of Unite Here Local 11, which filed the initiatives. 'We think that the city of Los Angeles should be very careful about providing subsidies and benefits to those particular industries.' The timing of the long-planned 'No Kings' protest proved fortuitous for those facing urgent ballot deadlines. As crowds gathered at a series of protests across the city, from downtown's City Hall to Playa Vista in the west, signature-gatherers fanned out amid sign-touting protesters to pull together the 92,998 signatures the LA Alliance for Tourism, Jobs and Progress will need by the end of month to qualify a referendum. Initiative and amendment committees seeking a spot on California's 2026 statewide ballot will soon begin sending petition carriers out to farmers' markets and strip malls, where they will have to convince unwilling shoppers to think politics when their minds are on produce. But in Los Angeles, campaigners are taking advantage of an often-apathetic city roused by President Donald Trump's aggressive immigration-enforcement tactics to help move the minimum-wage conflict from the city council to the ballot. 'You have a lot of civically minded, peaceful protesters at No Kings — these are the kinds of folks who are looking to be engaged politically, so it makes perfect sense … to show up there,' said Robb Korinke, a San Diego-based strategist who specializes in local ballot measures. The tactics that the industry-funded coalition has used to capture signatures have come under fire from backers of the $30 minimum wage law. Labor-friendly members of the LA City Council filed a motion to investigate what they said were misleading tactics on the part of the referendum effort's signature-gatherers, while unions have filed a similar complaint with Attorney General Rob Bonta, Los Angeles County DA Nathan Hochman and City Attorney Hydee Feldstein Soto. The referendum campaign denies the allegations. 'What it shows to me is that they have people out there essentially saying and doing anything to get their signatures on this referendum,' said LA City Councilmember Hugo Soto-Martinez. Now it's labor's turn to take to the streets. Unions have 120 days to gather around 140,000 valid signatures — and labor leaders are confident that they won't struggle to find the support they need. 'We poll on raising the minimum wage — the only thing that polls higher is the belief in God,' said Petersen. 'That has been our experience all along, in every one of these initiatives that we've either tried through the ballot and or through the law … and so I think we will be fine at the ballot.'
