Latest news with #SarahChen
Arab Times
09-06-2025
- Health
- Arab Times
Long-term study flags stroke risk from popular blood pressure pill
NEW YORK, June 9: A comprehensive 23-year medical study has raised concerns over the long-term safety of lisinopril, a widely prescribed blood pressure medication. The research shows a 19% higher risk of stroke-related death among lisinopril users compared to those taking other antihypertensive drugs, prompting fresh scrutiny over how blood pressure is managed in the long term. The long-term study tracked more than 33,000 patients and compared lisinopril to two other common medications: amlodipine and chlorthalidone. While the overall cardiovascular mortality rates were found to be similar across all three drugs, lisinopril was associated with a significantly higher stroke death rate. According to the study, the adjusted hazard ratio for stroke mortality with lisinopril was 1.19, indicating 119 stroke-related deaths in the lisinopril group for every 100 in the amlodipine group. 'These findings don't suggest lisinopril is inherently dangerous,' said Dr. Sarah Chen, lead researcher at Johns Hopkins. 'But they do indicate we need to adopt a more personalized approach to prescribing antihypertensive medications.' The study's unusually long duration — nearly 25 years — distinguishes it from most pharmaceutical trials, which typically last just 2–5 years. This extended follow-up allowed researchers to identify long-term trends not visible in shorter studies. One suspected mechanism behind the elevated risk is hyperkalemia — a buildup of potassium in the blood. Lisinopril, an ACE inhibitor, blocks the angiotensin-converting enzyme, which can lead to elevated potassium levels. In some patients, this increases the risk of arrhythmias that may trigger strokes. Unlike other ACE inhibitors, lisinopril is not a prodrug and is entirely processed by the kidneys. This makes patients with even mild kidney impairment more susceptible to drug accumulation, which could increase both its benefits and its risks. Another factor is the elevation of bradykinin, a peptide that causes blood vessel dilation. While this helps lower blood pressure, excessive bradykinin may lead to inflammation in brain vessels, potentially contributing to stroke risk. This same inflammatory process is believed to cause the common 'ACE inhibitor cough' experienced by many users. Who is most at risk? Not all patients are affected equally. According to the study: Patients over 65 without diabetes or chronic kidney disease faced the highest relative increase in stroke death risk.n Women were found to be 23% more vulnerable than men to lisinopril-related stroke mortality.n In contrast, individuals with diabetes or kidney disease may derive greater benefit from lisinopril, with its kidney-protective effects potentially outweighing the stroke risk.n Patients currently taking lisinopril are advised not to stop their medication without medical advice. The absolute increase in stroke risk remains relatively small — estimated at 2–3 additional deaths per 1,000 patients over two decades. However, patients — particularly those over 65 without diabetes or kidney disease — are encouraged to discuss these findings with their healthcare providers. Alternative medications such as amlodipine or chlorthalidone may offer a better safety profile for certain individuals. Doctors may also consider monitoring potassium levels quarterly, especially for patients continuing on lisinopril. The study also warns against combining lisinopril with potassium supplements or salt substitutes, which can amplify the risk of hyperkalemia. This study underscores the growing importance of personalized medicine in managing chronic conditions like hypertension. Researchers suggest that in the future, genetic testing might help predict how individual patients respond to specific drugs, including ACE inhibitors like lisinopril. 'Medication is not one-size-fits-all,' said Dr. Chen. 'As we learn more about genetic and physiological differences, we can better match the right drug to the right patient.' The findings do not call for an immediate halt in lisinopril use but emphasize the need for individualized treatment plans. Patients and physicians are urged to weigh risks and benefits carefully and to consider long-term implications when choosing antihypertensive therapies. As always, regular communication with a healthcare provider is key to ensuring safe and effective treatment.
The Star
06-06-2025
- Automotive
- The Star
Burning ship abandoned in Pacific carried several Chinese car brands
Ship carrying about 3,000 cars, including 800 EVs, has been abandoned in the middle of the Pacific Ocean after catching fire. - Reuters EAST ASIA (Bloomberg): A cargo ship that was abandoned in the middle of the Pacific Ocean after catching fire Tuesday was carrying cars from several Chinese automakers, according to people familiar with the matter. The Morning Midas was shipping around 3,000 cars from a range of manufacturers including Chery Automobile Co. and Great Wall Motor Co. to Mexico. It's unclear at this stage which brand's electric vehicle caught fire, the people said, who asked not to be identified discussing preliminary findings. The eastern Chinese city of Yantai, the port where the ship originated, also has a SAIC Motor Corp.-GM plant that produces the Buick Envision model, while the charterer of the vessel has been reported by local media to be Anji Logistics, a subsidiary of SAIC. Smoke was first seen coming from a deck of the vessel on Tuesday, whose cargo included about 800 EVs. The crew initiated firefighting procedures but the blaze couldn't be brought under control. Responders were deployed to support salvage and firefighting operations, the ship's manager Zodiac Maritime said in a statement. The US Coast Guard, which said the fire aboard the ship occurred approximately 300 miles south of Adak Island in Alaska, evacuated all 22 crew members and transferred them to a nearby merchant ship. Great Wall Motor had about 140 cars on the ship, although none of them were battery EVs and were not located at the deck where the fire started, one of the people said. A representative from Chery declined to comment. Great Wall Motor didn't immediately respond to a request for comment. Calls and an email to Anji Logistics weren't answered. --With assistance from Sarah Chen and Katia Dmitrieva. ©2025 Bloomberg L.P.
Mint
05-06-2025
- Automotive
- Mint
Burning Ship Bound for Mexico Carried Several Chinese Car Brands
(Bloomberg) -- A cargo ship that was abandoned in the middle of the Pacific Ocean after catching fire Tuesday was carrying cars from several Chinese automakers, according to people familiar with the matter. The Morning Midas was shipping around 3,000 cars from a range of manufacturers including Chery Automobile Co. and Great Wall Motor Co. to Mexico. It's unclear at this stage which brand's electric vehicle caught fire, the people said, who asked not to be identified discussing preliminary findings. The eastern Chinese city of Yantai, the port where the ship originated, also has a SAIC Motor Corp.-GM plant that produces the Buick Envision model, while the charterer of the vessel has been reported by local media to be Anji Logistics, a subsidiary of SAIC. Smoke was first seen coming from a deck of the vessel on Tuesday, whose cargo included about 800 EVs. The crew initiated firefighting procedures but the blaze couldn't be brought under control. Responders were deployed to support salvage and firefighting operations, the ship's manager Zodiac Maritime said in a statement. The US Coast Guard, which said the fire aboard the ship occurred approximately 300 miles south of Adak Island in Alaska, evacuated all 22 crew members and transferred them to a nearby merchant ship. Great Wall Motor had about 140 cars on the ship, although none of them were battery EVs and were not located at the deck where the fire started, one of the people said. A representative from Chery declined to comment. Great Wall Motor didn't immediately respond to a request for comment. Calls and an email to Anji Logistics weren't answered. --With assistance from Sarah Chen and Katia Dmitrieva. More stories like this are available on
Yahoo
13-05-2025
- Business
- Yahoo
Morning Magic Focus Drink Goes Viral on Social Media as the "Ultimate Morning Brain Boost"
Sheridan, Wyoming, May 13, 2025 (GLOBE NEWSWIRE) -- Brighter A.M.'s Morning Magic has exploded across social media after being dubbed "the ultimate focus drink" by productivity influencers, generating over 2.3 million views on TikTok and driving a staggering 600% increase in sales in just 30 days. The Grapefruit Guava flavored nootropic drink mix has become the latest sensation in the wellness space as users share dramatic "before and after" videos showcasing enhanced focus, productivity, and mental clarity. "We knew we had created something special, but we never expected to go viral this quickly," said David Longacre, founder and CEO of Brighter A.M. "People are absolutely blown away by how different Morning Magic makes them feel compared to traditional energy drinks and coffee. The Grapefruit Guava flavor has become an unexpected hit – users describe it as refreshing and sophisticated, unlike the overly sweet options that dominate the market." The viral phenomenon began when productivity coach @FocusMaster posted a split-screen video comparing his work output before and after drinking Morning Magic. "I've tried EVERYTHING for focus – this is actually insane," he wrote in a caption that resonated with millions struggling with brain fog and afternoon crashes. The video sparked the #MorningMagicChallenge, with thousands of users documenting their enhanced productivity, leading to Morning Magic selling out three times. What separates Morning Magic from the crowded energy drink market is its revolutionary science-backed formula containing 35% less caffeine than conventional energy drinks, paired with 11 premium brain-supporting ingredients: natural caffeine from green tea, L-Tyrosine, MCT Oil, Organic Lion's Mane Mushroom, Alpha-GPC, Choline, Vitamin C, B Vitamins, L-Theanine, KSM-66™ Ashwagandha, and Rhodiola Rosea. Users report experiencing the "Morning Magic Effect" – described as "unlocking a higher level of mental performance" – within 15 minutes of consumption. A remarkable 94% of customers surveyed said they could feel a noticeable difference in their focus and cognitive clarity compared to their usual morning beverages, without the jitters and crashes associated with traditional stimulants. "The Grapefruit Guava flavor was a deliberate choice to signal that this isn't your typical energy drink," explained Sarah Chen, Chief Science Officer at Brighter A.M. "We wanted a sophisticated, refreshing taste profile that would work well first thing in the morning. The citrus notes from grapefruit provide a clean, bright sensation while guava adds a tropical sweetness without any artificial ingredients or added sugars. The flavor perfectly complements the functional benefits." The unique taste has become part of the viral appeal, with users praising it as "addictively refreshing" and "the perfect morning flavor" in thousands of comments and reviews. Several viral videos feature first-time users' surprised reactions to the taste, with many expecting the typical medicinal flavor associated with functional beverages. Tech industry professionals and creative workers have emerged as particularly enthusiastic adopters, with numerous testimonials highlighting improved coding sessions, better meeting focus, enhanced creative problem-solving, and sustained productivity throughout the day. Morning Magic has rapidly spread through companies in tech hubs like Austin, Seattle, and Miami, with some offices now stocking it alongside or in place of coffee. "What makes Morning Magic truly revolutionary is that it delivers on what energy drinks have always promised but failed to provide," explained Dr. Michael Rivera, neurologist and independent advisor to Brighter A.M. "The synergistic blend of adaptogens like Ashwagandha and Rhodiola helps your body manage stress, while nootropics like Alpha-GPC and Lion's Mane support cognitive function. Combined with the balanced energy from natural caffeine and L-Theanine, you get a comprehensive boost to mental performance that you can actually feel." The company has seen an impressive 82% subscription renewal rate and maintains a 4.8/5 star average across over 1,200 verified reviews. Morning Magic's viral success has caught the attention of major retailers, with several national chains now in discussions to carry the product. "We're scaling production as quickly as possible to meet demand," Longacre added. "What's most rewarding is seeing how Morning Magic is genuinely improving people's daily lives. When someone messages us saying they finally finished that project they've been putting off for months or that they've had their most productive week in years, that's when we know we've created something truly valuable." Morning Magic is available in its signature Grapefruit Guava flavor on Each container provides 30 servings of the premium drink mix, priced at $59.98 with discounts available for subscribers. The company offers a 30-day money-back guarantee for first-time customers. About Brighter A.M.: Brighter A.M. creates wellness products helping people feel and perform better daily. Founded in 2024, we offer natural alternatives to energy drinks with effective, great-tasting Brighter A.M.: David Longacre (833) 408-1640 david@ ### For more information about Brighter A.M., contact the company here:Brighter Longacre(833) 408-1640david@ N Gould St # 44271Sheridan, WY 82801 CONTACT: David LongacreError in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
12-05-2025
- Health
- Yahoo
UJN Releases 2025's Best Berberine Supplements for Weight Loss Report
Los Angeles, California, May 12, 2025 (GLOBE NEWSWIRE) -- Union Jack News has released its highly anticipated 2025 consumer report identifying the top berberine supplements for weight-loss that are effective for losing stubborn fat & weight. This comprehensive analysis evaluated product quality, clinical effectiveness, and real-world user consumer report on berberine supplementSee UJN's recommended Berberine Supplements for Weight Loss Report Top-Ranked Berberine Formulas The report highlights of multiple quality formulations of the best berberine supplements that excelled in testing and effectiveness in providing weight loss benefits: See UJN's recommended Berberine Supplements for Weight Loss Report UJN's #1 Berberine Supplement (Brand uncovered in our sample report)"Our top performer showed clinically significant metabolic benefits in 89% of users." - Report Lead Researcher Generic Berberine (Low-cost / budget friendly supplement - purchase from established brand)The preferred choice for sustained weight management, with dietitians praising its optimal 1,200mg dosage. Berberine powder (Not easy to consume alone but recommended for adding into smoothies)Dual-action formula that supports both weight loss and cholesterol management. Barberry / Coptis chinensis (Natural Plant) - Recognized for exceptional manufacturing transparency and purity. Key Benefits of Quality Berberine Clinical studies confirm these advantages from top berberine supplements: Activates AMPK enzyme to boost metabolism Supports healthy blood sugar levels May reduce body fat accumulation Enhances gut microbiome diversity "Our testing revealed berberine's effects are dose-dependent. Products with less than 1,000mg per serving showed diminished results." - Dr. Sarah Chen, Metabolic Specialist What Consumers Should Know The report uncovered several critical findings: 30% of tested products failed quality standards Optimal results typically appear after 8-12 weeks Combined with lifestyle changes, users reported 2-3x better outcomes Third-party testing is essential for purity verification Report Frequently Asked Questions What makes the best berberine supplement? Look for: Minimum 1,000mg berberine HCL per serving Third-party purity verification Transparent sourcing information Positive consumer reviews How long until I see weight loss results? "Most users notice initial changes in 4-6 weeks, with optimal results after 3 months." - Clinical Nutritionist Mark Taylor Are there any side effects? Some users report mild digestive discomfort initially. The report recommends starting with half doses. Can berberine replace prescription medications? No. Always consult your healthcare provider before making changes to prescribed regimens. Where can I access the full report? Contact info(at)unionjacknews(dot)com for a complimentary sample of the complete 2025 Consumer Report. See UJN's recommended Berberine Supplements for Weight Loss Report All information in this article is for informational usage only based on the source material from Union Jack News's Consumer Report. Please consult with a doctor first before using any supplements, the opinions written in this article is solely on UJN's thoughts and opinion and is not medical advice. Press InquiriesUnion Jack Newsinfo@ in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
