Latest news with #Stockholm
Yahoo
a day ago
- Sport
- Yahoo
Wilson Bjorck Commits To Colorado College
Dave Schwarz, dschwarz@ Djurgardens IF J20 forward Wilson Bjorck has committed to Colorado College, it was announced earlier this week. Bjorck, a product of Stockholm, Sweden, split time this season between the J20 Nationell and the pro level (10 games with Djurgardens IF in HockeyAllsvenskan and one game with Tyreso/Hanviken in HockeyEttan). Over 11 pro games, Bjorck went pointless, but he scored 28 goals and added 39 assists for 67 points in 43 regular season games in the J20 Nationell. Advertisement Eligible for the 2025 NHL Draft, Bjorck spent his time playing his hockey in Djurgardens IF's system and IFK Taby HC's system growing up. His best season offensively came this year, where he really showed his skills with the puck on his stick. As Bjorck comes over to North America for the very first time, his skills should allow him to be an immediate difference maker for the Tigers. Likely to hear his name called at the draft this week, Bjorck will be one to watch as he heads into his freshman season.
New Indian Express
a day ago
- New Indian Express
Swedish criminal who helped inspire 'Stockholm syndrome' theory dies: Report
Clark Olofsson, who is one of the two criminals involved in the kidnapping and bank robbery during the year 1973 in Swedish capital, which gave rise to the expression "Stockholm syndrome," has died at the age of 78 following a lengthy illness, the BBC reports quoting his family. During the six-day siege, Olofsson's hostages not only began to sympathise with him and his accomplice, but defended their actions while growing hostile to the police outside. The incident lends its name to a theorised psychological condition whereby kidnap victims develop affections for their captor, BBC said. According to the report, the notorious bank siege was instigated by one Jan-Erik Olsson. After seizing three women and a man hostage, he demanded Olofsson, who he had previously befriended in prison, be brought to the bank from jail. Swedish authorities agreed to his demand, and Olofsson, a repeated offender who spent much of his life in prison, entered the bank, which was surrounded by police. Years later, in an interview with the Aftonbladet newspaper, he claimed he was asked to work as an inside man to keep the captives safe in exchange for a reduced sentence, but accused officials of not honouring the agreement.
Medscape
a day ago
- Health
- Medscape
Hydroxychloroquine May Tame Preeclampsia in Lupus Patients
Use of hydroxychloroquine during pregnancy in patients with systemic lupus erythematosus (SLE) is associated with a reduced risk for preeclampsia, according to a recent nationwide cohort study. A population-based analysis from Sweden found that women with SLE taking hydroxychloroquine had about half the risk for preeclampsia compared with those not taking it, but there was no clear association between hydroxychloroquine use and preterm birth risk. 'These findings suggest possibly favorable, or at least not harmful, associations between hydroxychloroquine and preeclampsia and preterm delivery in pregnancies in women with SLE, supporting the current recommendations for hydroxychloroquine treatment during pregnancy in these patients,' wrote Ngoc V. Nguyen, MPH, a PhD candidate at the Karolinska Institutet in Stockholm, Sweden, and his colleagues in The Lancet Rheumatology . '[Hydroxychloroquine] may actually reduce the risk of preeclampsia,' Nguyen told Medscape Medical News . Joshua Copel, MD, a professor of obstetricis, gynecology, and reproductive sciences and of pediatrics at Yale School of Medicine, New Haven, Connecticut, told Medscape Medical News the findings show that 'hydroxychloroquine certainly doesn't seem to cause an increased risk for spontaneous preterm birth, and it probably reduces the risk for preeclampsia or at least delays the onset of preeclampsia.' The researchers used the Swedish Medical Birth Register to identify all 959 singleton pregnancies among 685 women with SLE in Sweden between January 2007 and December 2022. Using the Prescribed Drug Register, they determined which patients had received at least two dispensations between 3 months before pregnancy through the end of the first trimester. Among the 42% of pregnancies that were nulliparous, 43% were exposed to hydroxychloroquine and 57% were unexposed. Among the other 58% of pregnancies that were parous, 40% were exposed and 60% were unexposed. Patients had an average age of 32 years and an average first-trimester BMI ranging from 23.7 to 24.9 across the different groups. They had been diagnosed with lupus for 5.4-6.8 years, and rates of prior miscarriages ranged from 19% to 38% across the groups. Preeclampsia occurred in 11% of exposed and 13% of unexposed nulliparous pregnancies and in 5% of exposed and 6% of unexposed parous pregnancies. Preterm birth occurred in 19% of exposed and 15% of unexposed nulliparous pregnancies and in 12% of exposed and 12% of unexposed parous pregnancies. After adjustment for confounders, these numbers translated to an overall 49% reduced risk for preeclampsia in those exposed to hydroxychloroquine (95% CI, 0.31-0.79; P = .003). Stratified by parity, however, the 59% preeclampsia risk reduction in nulliparous pregnancies exceeded the threshold for statistical significance (95% CI, 0.33-1.08; P = .085). The 44% reduction in parous pregnancies was significant (95% CI, 0.22-0.89; P = .02). Questions Remain Though these findings 'add to a growing body of evidence suggesting hydroxychloroquine may help lower the risk of preeclampsia,' Nguyen told Medscape Medical News , 'it's worth noting that not all studies have shown statistically significant effects [potentially because of] how hydroxychloroquine use was defined, how well patients adhered to it, or whether key factors like BMI and smoking were accounted for.' Alfred Kim, MD, PhD, an associate professor of rheumatology at Washington University Medicine in St. Louis, told Medscape Medical News that hydroxychloroquine 'has a well-established antithrombotic property,' as seen with antiphospholipid syndrome, and 'preeclampsia is a prothrombotic condition due to substantial endothelial dysfunction, driving complement and coagulation cascade activation.' 'It is not completely clear how hydroxychloroquine attenuates thrombosis, though,' Kim said. 'There are nice data suggesting that hydroxychloroquine inhibits platelet activation and thrombus formation, both of which can promote a preeclamptic state.' Other possibilities, Nguyen added, include antioxidant activity, improved placental perfusion, and stabilization of endothelial function, any of which could also, in theory, reduce the risk for preterm birth in certain cases. However, this study found no association with preterm birth overall (risk ratio [RR], 0.95; 95% CI, 0.67-1.34; P = .76), in nulliparous births (RR, 1.1; P = .69), or in parous births (RR, 0.75; P = .28). Adherence Barriers Present Challenges Grégoire Martin de Frémont, Gaëlle Guettrot-Imbert, and Nathalie Costedoat-Chalumeau of Paris City University in Paris wrote in an accompanying editorial in The Lancet Rheumatology that 'by suggesting a beneficial effect on preeclampsia, the rigorous and valuable findings reported by the authors provide an additional rationale for the use of hydroxychloroquine in all pregnant women with SLE, as currently recommended.' They add, however, that 'obstacles to its optimal use persist, including drug unavailability, lack of prescription, and, in many cases, patients' reluctance to take it.' Kim agreed that many barriers remain to hydroxychloroquine adherence during pregnancy. 'Sometimes it's due to the patient not fulfilling the prescription, whether this is due to cost — which is typically not an issue with hydroxychloroquine — to inadequate comprehension due to low literacy, cognitive issues, language or visual barriers to a lack of trust in the medication or the medical team prescribing hydroxychloroquine,' Kim said. Nguyen agreed that the challenge of adherence is complex, with hurdles that include misinformation about safety, mixed messages from providers, and challenges such as age, disease severity, or pill burden. 'Our study might help chip away at some of these barriers by offering strong evidence for benefit, not just safety. If we can reframe hydroxychloroquine as something that's protective during pregnancy — not just 'safe enough' — that might help patients feel more comfortable and providers more proactive,' he said. The research was funded by the US National Institutes of Health and the Ingegerd Johansson Donation. The authors reported no disclosures. Costedoat-Chalumeau reported grants from UCB and Roche and honoraria from Bristol Myers Squibb. Copel serves on the advisory board for Janssen Pharmaceuticals, Nuvo, SimHawk, and Pulsenmore; receives royalties from Elsevier and UpToDate; and owns a company that manufactures prenatal vitamins. Kim receives royalties from Kypha Inc.; sponsored research agreements with AstraZeneca, Bristol Myers Squibb, CRISPR Therapeutics, and Novartis; and has done consulting or speaking for AbbVie, Amgen, Atara Biotherapeutics, Aurinia Pharmaceuticals, Cargo Tx, Exagen Diagnostics, GlaxoSmithKline, Genentech/Roche, Hinge Bio, Invivyd, Johnson & Johnson, UpToDate, and Zenas BioPharma.
Malay Mail
a day ago
- Politics
- Malay Mail
Swedish robber Clark Olofsson who inspired the term ‘Stockholm syndrome', dies at 78
KUALA LUMPUR, June 27 — Clark Olofsson, the Swedish criminal whose role in a 1973 Stockholm bank robbery inspired the term 'Stockholm syndrome,' has died at 78, his family confirmed to Dagens ETC, as reported by the BBC. The six-day bank siege saw Olofsson and his accomplice, Jan-Erik Olsson, take four hostages who grew sympathetic towards them while increasingly distrustful of the police. This counterintuitive response was later named Stockholm syndrome, a theorised psychological condition where captives develop feelings of attachment to their captors. The BBC reported that the siege began with Olsson taking three women and one man hostage at a Stockholm bank, demanding Olofsson be brought from prison to the scene. Swedish authorities complied, allowing Olofsson to join Olsson inside the bank, which was under heavy police surveillance. Olofsson claimed in a later interview with Sweden's Aftonbladet newspaper that authorities had asked him to protect the hostages in exchange for a reduced sentence. However, he alleged the agreement was not honoured. During the standoff, Olofsson persuaded one of the hostages, Kristin Enmark, to call the Swedish prime minister, Olof Palme. She expressed trust in her captors and asked to leave the bank with them, telling Palme: 'I fully trust Clark and the robber... They haven't done a thing to us.' The incident concluded when police used tear gas to storm the building. Despite being freed, hostages initially hesitated to leave, fearing their captors would be harmed. They later refused to testify against Olofsson and Olsson in court. As highlighted by the BBC, the term Stockholm syndrome was coined by Swedish criminologist Nils Bejerot. While the concept gained attention in high-profile cases, such as the 1974 kidnapping of Patty Hearst, it remains contested among experts. Enmark herself dismissed the idea during a BBC Sideways podcast in 2021, saying it unfairly blames victims. Olofsson, who spent much of his life in prison for armed robbery, drug offences, and other crimes, was released in 2018. The BBC noted that his life story was dramatized in the 2022 Netflix series 'Clark', with actor Bill Skarsgård portraying him. The BBC reported that Olofsson's family confirmed his death following a lengthy illness, marking the end of a life that profoundly impacted criminal history and popular psychology.
Medscape
a day ago
- Health
- Medscape
Diminishing Returns With Broader Use of ADHD Meds?
It's well known that medications used to treat attention-deficit hyperactivity disorder (ADHD) do more than address the core symptoms of inattention, hyperactivity, and impulsivity. They have also been associated with significant reductions in the risk for serious real-world outcomes such as self-harm, unintentional injury, car crashes, and crime. However, a large-scale Swedish study has found that the magnitude of associations between ADHD medication use and these real-world outcomes appears to have weakened, in parallel with rising prescription rates. 'The declining strength of the associations of ADHD medication and real-world outcomes could be attributed to the expansion of prescriptions to a broader group of individuals having fewer symptoms or impairments,' first author Lin Li, PhD, Karolinska Institutet, Stockholm, Sweden, and colleagues wrote. The findings were published online on June 25 in JAMA Psychiatry. Waning Real-World Impact? The rate of ADHD medication use has risen substantially in many countries over the past two decades. With treatment now reaching a broader population of individuals who may have less severe symptoms, an emerging question is whether there remains a meaningful reduction in real-world harm. To investigate, Li and colleagues analyzed health data from Swedish national registers for 247,420 individuals aged 4-64 years who were prescribed ADHD medications between 2006 and 2020. They employed a self-controlled case series design, which allowed individuals to serve as their own controls. Outcomes included rates of self-harm, unintentional injury, traffic crashes, and crime measured during medicated vs nonmedicated periods. Over the 14-year study period, ADHD medication use rose sharply in Sweden — from 0.6% to 2.8% in children and from 0.1% to 1.3% in adults. ADHD medication use was consistently linked to reduced risks for self-harm (incidence rate ratio [IRR] range, 0.77-0.85), unintentional injury (IRR range, 0.87-0.93), traffic crashes (IRR range, 0.71-0.87) and crime (IRR range, 0.73-0.84) across all analyzed time periods, age groups, and sexes. However, the magnitude of risk reduction for these real-world outcomes diminished significantly over time ( P < .01) and was not fully explained by the age and sex distribution of people taking ADHD medication. The study team noted that the strongest associations between ADHD medication and reduced risk for real-world outcomes were consistently observed in women during the earliest study period (2006-2010), a time when only the most severe ADHD cases in women were being diagnosed and treated. Over time, as more women were prescribed ADHD medication, the sex differences on the various real-world outcomes narrowed, investigators said. In an accompanying editorial in JAMA Psychiatry , Ryan S. Sultan, MD, Department of Psychiatry, College of Physicians and Surgeons, Columbia University and the New York State Psychiatric Institute, New York City, and colleagues said it's 'critically' important to remember that the purpose of ADHD treatment is not primarily to prevent arrests, car crashes, or self-harm crises but to improve patients' daily functioning and quality of life. 'The accumulation of evidence makes one thing clear: When used appropriately, ADHD medications can help affected people not just feel better but live safer, more productive lives. This message is important as many individuals with ADHD still do not receive medication as their first-line treatment, despite medications having the most robust evidence for ADHD,' the editorialists wrote.
