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What is life? A little microbe raises big questions.
What is life? A little microbe raises big questions.

Yahoo

time06-07-2025

  • Science
  • Yahoo

What is life? A little microbe raises big questions.

It's tiny and needy, but is it alive? That's a question prompted by recent research that highlights a surprisingly complex part of biology. The organism in question is a microbe called Sukunaarchaeum mirabile, discovered by researchers in Canada and Japan who were looking at the DNA of a species of marine plankton, according to a new paper published on bioRxiv. They've found it's unusually reliant on an alive host to survive, which could further blur the lines between cellular life and viruses — which generally considered to not be alive. The National Human Genome Research Institute describes viruses as existing "near the boundary between the living and the nonliving." Viruses can't function without interacting with a living cell. On their own, they're also essentially inert – unable to move – as a 2017 study notes. Enter Sukunaarchaeum mirabile, which could complicate things further. "This organism represents a totally new branch in the archaeal tree of life," lead researcher Takuro Nakayama of the University of Tsukuba told USA TODAY. (Archaea are microorganisms that define the limits of life on Earth.) "Sukunaarchaeum is not a virus, but a highly streamlined cellular organism," Nakayama said. According to the new study, which has yet to be peer-reviewed, "the discovery of Sukunaarchaeum pushes the conventional boundaries of cellular life and highlights the vast unexplored biological novelty within microbial interactions." Named for a Japanese deity known for its tiny size, Sukunaarchaeum has one of the smallest genomes ever recorded: "Its genome is drastically reduced – less than half the size of the previously smallest known archaeal genome," Nakayama said. The authors in the study write that "its genome is profoundly stripped-down, lacking virtually all recognizable metabolic pathways, and primarily encoding the machinery for its replicative core: DNA replication, transcription, and translation." "This suggests an unprecedented level of metabolic dependence on a host, a condition that challenges the functional distinctions between minimal cellular life and viruses,' the study says. "Sukunaarchaeum could be just the tip of the iceberg, pointing to a hidden diversity of life forms with ultra-reduced genomes within the so-called 'microbial dark matter,'" Nakayama told USA TODAY. Indeed, the discovery of Sukunaarchaeum's bizarrely viruslike way of living 'challenges the boundaries between cellular life and viruses,' Kate Adamala, a synthetic biologist at the University of Minnesota Twin Cities who was not involved in the work, told Science magazine. 'This organism might be a fascinating living fossil – an evolutionary waypoint that managed to hang on.' The study concludes that "further exploration of symbiotic systems may reveal even more extraordinary life forms, reshaping our understanding of cellular evolution." "I am not an expert on the philosophical definition of 'life," Nakayama said, adding that the definition is not uniform among scientists and is a subject of continuous debate. "Many scientists would agree that cellular structure, the ability to replicate, and the ability to metabolize are key features of life. Viruses typically lack these features," he said. "The discovery of Sukunaarchaeum is interesting in this context because it lacks one of those key features: metabolism. The existence of a cellular organism that seemingly lacks its own metabolism provides a new and important perspective to the ongoing discussion about the definition and minimal requirements of life." Contributing: Joel Shannon, USA TODAY This article originally appeared on USA TODAY: A mysterious microbe raises questions about life

What is life? A little microbe raises big questions.
What is life? A little microbe raises big questions.

USA Today

time06-07-2025

  • Science
  • USA Today

What is life? A little microbe raises big questions.

It's tiny and needy, but is it alive? That's a question prompted by recent research that highlights a surprisingly complex part of biology. The organism in question is a microbe called Sukunaarchaeum mirabile, discovered by researchers in Canada and Japan who were looking at the DNA of a species of marine plankton, according to a new paper published on bioRxiv. They've found it's unusually reliant on an alive host to survive, which could further blur the lines between cellular life and viruses — which generally considered to not be alive. The National Human Genome Research Institute describes viruses as existing "near the boundary between the living and the nonliving." Viruses can't function without interacting with a living cell. On their own, they're also essentially inert – unable to move – as a 2017 study notes. Enter Sukunaarchaeum mirabile, which could complicate things further. What is it? "This organism represents a totally new branch in the archaeal tree of life," lead researcher Takuro Nakayama of the University of Tsukuba told USA TODAY. (Archaea are microorganisms that define the limits of life on Earth.) "Sukunaarchaeum is not a virus, but a highly streamlined cellular organism," Nakayama said. According to the new study, which has yet to be peer-reviewed, "the discovery of Sukunaarchaeum pushes the conventional boundaries of cellular life and highlights the vast unexplored biological novelty within microbial interactions." Named for a Japanese deity Named for a Japanese deity known for its tiny size, Sukunaarchaeum has one of the smallest genomes ever recorded: "Its genome is drastically reduced – less than half the size of the previously smallest known archaeal genome," Nakayama said. The authors in the study write that "its genome is profoundly stripped-down, lacking virtually all recognizable metabolic pathways, and primarily encoding the machinery for its replicative core: DNA replication, transcription, and translation." "This suggests an unprecedented level of metabolic dependence on a host, a condition that challenges the functional distinctions between minimal cellular life and viruses,' the study says. 'The tip of the iceberg' "Sukunaarchaeum could be just the tip of the iceberg, pointing to a hidden diversity of life forms with ultra-reduced genomes within the so-called 'microbial dark matter,'" Nakayama told USA TODAY. Indeed, the discovery of Sukunaarchaeum's bizarrely viruslike way of living 'challenges the boundaries between cellular life and viruses,' Kate Adamala, a synthetic biologist at the University of Minnesota Twin Cities who was not involved in the work, told Science magazine. 'This organism might be a fascinating living fossil – an evolutionary waypoint that managed to hang on.' The study concludes that "further exploration of symbiotic systems may reveal even more extraordinary life forms, reshaping our understanding of cellular evolution." What does 'life' mean to scientists? "I am not an expert on the philosophical definition of 'life," Nakayama said, adding that the definition is not uniform among scientists and is a subject of continuous debate. "Many scientists would agree that cellular structure, the ability to replicate, and the ability to metabolize are key features of life. Viruses typically lack these features," he said. "The discovery of Sukunaarchaeum is interesting in this context because it lacks one of those key features: metabolism. The existence of a cellular organism that seemingly lacks its own metabolism provides a new and important perspective to the ongoing discussion about the definition and minimal requirements of life." Contributing: Joel Shannon, USA TODAY

Meet the organism which hangs somewhere between life and death
Meet the organism which hangs somewhere between life and death

Time of India

time03-07-2025

  • Science
  • Time of India

Meet the organism which hangs somewhere between life and death

Scientists have discovered Sukunaarchaeum mirabile, a unique archaeon residing within marine plankton, challenging traditional definitions of life. This microbe possesses a stripped-down genome, enabling protein production but lacking metabolic pathways, blurring the lines between cellular life and viruses. Its discovery prompts a reevaluation of life's boundaries and evolutionary origins. Scientists have long debated what truly counts as 'alive.' On one side of the spectrum lie conscious animals and self-replicating single-celled organisms, whereas on the other side are viruses, which are the biological entities that can only function once they hijack a host. Viruses don't grow, reproduce independently, or generate their own energy, so they're usually excluded from the tree of life. But life's boundaries aren't always clear-cut. New discoveries are challenging the binary notion of 'living' versus 'non-living.' A recently discovered organism is a surprising microbe that shares traits with both viruses and cellular life. It can construct its own ribosomes and messenger RNA, yet it lacks most metabolic pathways and relies heavily on its host. So this brings us to some unanswered questions like, what defines life? Where do we draw the line? And could this microbe represent a missing link in evolutionary biology? Researchers led by Ryo Harada at Dalhousie University uncovered an unusual archaeal organism within the marine plankton Citharistes regius. While studying the plankton's bacterial genome, they discovered a circular DNA fragment that didn't match any known species. Detailed analysis showed the scientists that it belongs to the Archaea domain and is provisionally named Sukunaarchaeum mirabile, inspired by a tiny Japanese deity. This virus can produce its own proteins! Surprisingly, its genome is just 2,38,000 base pairs, which is about half the size of the smallest previously known archaeal genome, which was 490 kbp. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Искате да научите повече за новото BMW 2 Gran Coupe? BMW Научете повече Undo 'Its genome is profoundly stripped‑down, lacking virtually all recognizable metabolic pathways, and primarily encoding the machinery for its replicative core: DNA replication, transcription, and translation,' the team of researchers revealed in the study. This minimal genome means an undefined metabolic dependence on its host. Still, Sukunaarchaeum retains key machinery most viruses lack, like the genes for building ribosomes, transfer RNA, and messenger RNA. Unlike viruses, which rely fully on host machinery, this archaeon can perform fundamental cellular processes. The team says, 'Sukunaarchaeum may represent the closest cellular entity discovered to date that approaches a viral strategy of existence'. This virus belongs to an old branch of a family tree Study also reveals that the scientists found that Sukunaarchaeum mirabile belongs to a very old and unique branch of the Archaea family tree, which is so unique that it may come from a group of microbes that have never been observed before. Even though researchers have done tons of environmental DNA sequencing over the years, this strange little organism stayed hidden inside plankton DNA until now. Its tiny, simplified genome is making scientists rethink how we define life. Sukunaarchaeum blurs the line between the smallest living cells and complex viruses. It can copy its own DNA and make proteins, things that viruses usually can't do on their own, but it still relies completely on its host to survive because it can't produce its own energy. In short, this organism sits in a gray area between life as we know it and the strange, parasitic world of viruses.

Scientists Just Discovered a Creature That Breaks the Rules of Life
Scientists Just Discovered a Creature That Breaks the Rules of Life

Yahoo

time01-07-2025

  • Science
  • Yahoo

Scientists Just Discovered a Creature That Breaks the Rules of Life

In the ever-expanding universe of microscopic life, scientists have uncovered something that might force us to redraw the boundaries of what counts as 'alive.' Meet Sukunaarchaeum mirabile, a tiny cellular oddity recently discovered by researchers in Canada and Japan, according to a new paper published on the bioRxiv server. It's not quite a virus, and it's not fully a living cell either, but it carries traits of both. Named after a Japanese deity famed for its small size, Sukunaarchaeum sports one of the smallest genomes ever recorded—just 238,000 base pairs, less than half that of the previous smallest-known archaeal genome. And while viruses are typically excluded from the tree of life due to their reliance on host cells for key functions, this organism complicates that definition in a big way. Like a virus, Sukunaarchaeum relies on a host to carry out many of its biological tasks. But unlike a virus, it's capable of building its own ribosomes and messenger RNA. These are the basic building blocks that enable an organism to translate genetic code into protein, which is something viruses can't do on their own. Its stripped-down genome reveals an obsessive focus on replication. It contains little else besides the machinery needed to copy itself. 'Its genome is profoundly stripped-down, lacking virtually all recognizable metabolic pathways, and primarily encoding the machinery for its replicative core: DNA replication, transcription, and translation,' the researchers wrote. This means it leans heavily on its host for everything from energy to nutrients. The discovery happened almost by accident. Molecular biologist Ryo Harada and his team at Dalhousie University were examining the DNA of a marine plankton species when they found a strand of genetic material that didn't match any known organism. After digging deeper, they identified it as part of the Archaea domain—a group of ancient microbes from which modern complex cells likely evolved. If Sukunaarchaeum proves anything, it's that nature doesn't follow strict definitions. In fact, this discovery could fundamentally reshape how we think about cellular evolution and the blurry line between life and Just Discovered a Creature That Breaks the Rules of Life first appeared on Men's Journal on Jul 1, 2025

Scientists Discovered a New Creature That Exists Between Life and Not-Life
Scientists Discovered a New Creature That Exists Between Life and Not-Life

Yahoo

time30-06-2025

  • Science
  • Yahoo

Scientists Discovered a New Creature That Exists Between Life and Not-Life

Here's what you'll learn when you read this story: Viruses typically aren't considered 'alive,' as many core biological functions are outsourced to their hosts. But a newly discovered organism appears to straddle the line between virus and cell. Like a virus, this new organism 'Sukunaarchaeum mirabile' outsources some functions to its host, but can still create its own ribosomes and RNA. Its genome is also surprisingly small, and is roughly half the size (238,000 base pairs) of the next-smallest archaeal genome. At first glance, creating a definition for 'life' seems somewhat straightforward. Sentient animals all the way down to single-celled organisms capable of reproduction are welcome on the tree of life, but there are other organisms that challenge this understanding, like viruses. Because virus don't grow, reproduce on their own, or make their own energy, they're typically excluded from definitions of life. But once a virus infects a host, it's immensely active, and can be responsible for world-altering events (see: Spanish flu, ebola, COVID-19, and so on). However, life is complicated, and this controversial categorization of 'life' and 'not life' can have gray areas in which organisms appear to defy the expectations of both camps. Recently, scientists found a new member of this head-scratching cadre. In a new paper published on the bioRxiv server, researchers in Canada and Japan outlined how they identified a new cellular entity that appeared to straddle the typical definitions of a virality and cellular life. Currently named 'Sukunaarchaeum mirabile' (after a deity in Japanese mythology known for its small stature), this entity contains the necessary genes to create its own ribosomes and messenger RNA—something your typical virus lacks. But like a virus, it offloads certain biological functions onto its host and it appears singularly obsessed with replicating itself. 'Its genome is profoundly stripped-down, lacking virtually all recognizable metabolic pathways, and primarily encoding the machinery for its replicative core: DNA replication, transcription, and translation,' the authors wrote. 'This suggests an unprecedented level of metabolic dependence on a host, a condition that challenges the functional distinctions between minimal cellular life and viruses.' Led by Ryo Harada, a molecular biologist from Dalhousie University in Halifax, Nova Scotia, the team chanced upon this strange creature while studying the bacterial genome of the marine plankton Citharistes regius. Within the genomic data, Harada and his team found a loop of DNA that didn't match with any known species. They eventually determined that the organism belonged to the domain Archaea—a group associated with prokaryotic cells, but from which eukaryotic cells (i.e. you and me) ultimately descended a couple billion years ago. Perhaps the most remarkable feature of Sukunaarchaeum is its extreme genome reduction, with only 238,000 base pairs of DNA. Viruses, as Live Science points out, can contain many hundreds of thousands more base pairs, and can even reach up into the millions. As for fellow archaea, the smallest known complete genome within this group stretches to 490,000 base pairs, meaning that Sukunaarchaeum contains less than half the number of base pairs posessed by even the smallest archaeal genome. 'The discovery of Sukunaarchaeum pushes the conventional boundaries of cellular life and highlights the vast unexplored biological novelty within microbial interactions,' the authors wrote. 'Further exploration of symbiotic systems may reveal even more extraordinary life forms, reshaping our understanding of cellular evolution.' You Might Also Like The Do's and Don'ts of Using Painter's Tape The Best Portable BBQ Grills for Cooking Anywhere Can a Smart Watch Prolong Your Life?

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