Latest news with #Tyvaso
Yahoo
19 hours ago
- Business
- Yahoo
United Therapeutics Corporation (UTHR) Completes Phase 3 Enrollment for Promising PAH Drug Ralinepag
We recently published United Therapeutics Corporation stands eighth among the most undervalued stocks. United Therapeutics Corporation (NASDAQ:UTHR) is among the most undervalued stocks to invest in. It is a biotechnology company focused on treating pulmonary arterial hypertension (PAH) and advancing organ transplantation alternatives through xenotransplantation and regenerative medicine. On June 23, 2025, United Therapeutics Corporation (NASDAQ:UTHR) announced the completion of enrollment in its Phase 3 ADVANCE OUTCOMES trial for ralinepag, a once-daily oral prostacyclin receptor agonist for PAH. The trial enrolled 728 patients, and top-line data is expected in the first half of 2026. Ralinepag showed strong Phase 2 results, significantly reducing pulmonary vascular resistance, a key marker of disease progression. The successful enrollment marks a major milestone as ralinepag could become a new standard of care, offering a more convenient and potentially more effective oral therapy for PAH. This move strengthens the company's leadership in PAH, complementing its existing Tyvaso franchise and advancing its pipeline of differentiated therapies aimed at improving patient outcomes. A healthcare professional wearing a health communications device discussing patient data with a colleague. United Therapeutics Corporation (NASDAQ:UTHR) is also presenting long-term ralinepag data at leading scientific conferences, reinforcing its commitment to transparency and scientific rigor. While exploring related areas such as idiopathic pulmonary fibrosis (IPF) and organ transplant innovations, the company's near-term focus remains firmly on transforming PAH treatment through innovative, patient-friendly therapies. While we acknowledge the potential of UTHR as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: 30 Stocks That Should Double in 3 Years and 11 Hidden AI Stocks to Buy Right Now. Disclosure: None. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
3 days ago
- Business
- Yahoo
Morgan Stanley Trims United Therapeutics (UTHR) Price Target, Maintains Buy Rating
United Therapeutics Corporation (NASDAQ:UTHR) is one of the high-margin pharma stocks to buy now. Morgan Stanley has lowered its price target on United Therapeutics (NASDAQ: UTHR) to $328 from $348, while maintaining an Equal Weight rating, amid broader headwinds facing the biotech and pharmaceutical sectors. The firm flagged persistent macroeconomic challenges and regulatory uncertainties that continue to weigh on investor sentiment across the space. A team of scientists in a laboratory, running tests on a biotechnology product. In a research note to clients, the firm pointed to several factors pressuring large-cap healthcare names this year, including policy volatility around drug pricing, ongoing debates over international transfer pricing, and staffing turnover at the FDA. Against that backdrop, United Therapeutics is facing specific questions about near-term sales performance, particularly around its key pulmonary arterial hypertension therapy, Tyvaso. Morgan Stanley is now modeling second-quarter Tyvaso sales of $442 million, below the Street consensus of $483 million. Total revenue is expected to reach $768 million, also under consensus estimates of $805 million. The firm attributes the cautious outlook to potential softness in Tyvaso DPI uptake and less momentum in patient onboarding than previously projected. Despite strong fundamentals and long-term growth driver, including its organ manufacturing pipeline, Morgan Stanley appears to be taking a more conservative stance in the near term. With shares already reflecting much of the upside potential, the firm sees a more balanced risk-reward profile at current levels. While we acknowledge the potential of UTHR as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: Top 10 Healthcare AI Stocks to Buy According to Hedge Funds and 10 Best Industrial Automation Stocks to Buy for the Next Decade Disclosure: None. This article is originally published at Insider Monkey.
Yahoo
24-06-2025
- Business
- Yahoo
Leerink Partners Slashes MannKind Corporation's (MNKD) Price Target to $7, Keeps a Buy Rating
MannKind Corporation (NASDAQ:MNKD) is one of the 13 Best Long-Term Penny Stocks to Buy According to Analysts. On June 19, analyst Faisal Khurshid of Leerink Partners reiterated a Buy rating on MannKind Corporation (NASDAQ:MNKD), reducing the price target to $7 from $9. Despite some near-term uncertainties, the analyst based the rating on the company's long-term growth, stating that the stock is currently undervalued. A close-up of a doctor's hand pressing on an inhaler, conveying the effect of the company's therapeutic products. Calling the company a unique player in the SMID-cap biotech sector, the analyst stated that MannKind Corporation (NASDAQ:MNKD) holds an optimistic position because of its modest Afrezza sales and cash flow positive status from Tyvaso DPI royalties. The company is also focusing on inhaled therapies for orphan respiratory indications, which further presents several opportunities for success, according to the analyst. While Khurshid acknowledged the risks associated with the Tyvaso DPI royalty stream, especially with Yutrepia's recent approval and position as a competitor, he also expressed near-term optimism about the commercial trajectory of Tyvaso DPI and its potential effect on the company's financials. The analyst considers the upcoming results from the Phase 3 TETON-2 trial of Tyvaso in IPF to be a notable catalyst for the MannKind Corporation (NASDAQ:MNKD). MannKind Corporation (NASDAQ:MNKD) is a biopharmaceutical company that develops and commercializes innovative therapeutic devices and products that address serious unmet medical needs for endocrine and orphan lung diseases. The company's pipeline and products include Afrezza, Pediatric Afrezza, V-Go, Tyvaso DPI, MNKD-101, MNKD-201, MNKD-301, and MNKD-501. While we acknowledge the potential of MNKD as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: The Best and Worst Dow Stocks for the Next 12 Months and 10 Unstoppable Stocks That Could Double Your Money. Disclosure: None. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
13-06-2025
- Business
- Yahoo
Analyst Kelly Shi from Jefferies Maintained a Buy Rating on Insmed Incorporated (INSM)
Insmed Incorporated (NASDAQ:INSM) is among the 13 Biotech Stocks with Huge Upside Potential. Kelly Shi of Jefferies has given Insmed Incorporated (NASDAQ:INSM) a buy recommendation, stating that she is confident in the TPIP treatment's impending Phase 2 data for pulmonary arterial hypertension. A biopharmaceutical research team taking notes in front of a laboratory's microscope. Shi anticipates a substantial decrease in pulmonary vascular resistance, the main outcome of the trial, of 20%, which is regarded as a definite success. If the results are encouraging, TPIP may replace Tyvaso, the current standard treatment. On June 4, Wells Fargo reaffirmed its Buy recommendation, with a price objective of $107. Shi points out that TPIP's once-daily dosage is a significant benefit over Tyvaso's four-times-daily schedule, which could increase adherence and make it more appealing to patients as well as physicians. The efficacy potential of TPIP is supported by interim study results that show additional advantages in six-minute walk distance (6MWD). Shi expects significant market penetration in light of these considerations, which could lead to an increase in Insmed Incorporated (NASDAQ:INSM)'s valuation. Both analysts highlight that if future trial results live up to predictions, TPIP has the potential to completely change the way that PAHs are treated. Insmed Incorporated (NASDAQ:INSM) is a biopharmaceutical firm that improves the lives of individuals suffering from serious and rare diseases. While we acknowledge the potential of INSM as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: 10 High-Growth EV Stocks to Invest In and 13 Best Car Stocks to Buy in 2025. Disclosure. None. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
13-06-2025
- Business
- Yahoo
United Therapeutics (UTHR) Soars 3.5%: Is Further Upside Left in the Stock?
United Therapeutics UTHR shares soared 3.5% in the last trading session to close at $286.14. The move was backed by solid volume with far more shares changing hands than in a normal session. This compares to the stock's 7.7% loss over the past four weeks. This rise can be attributed to a recovery in the company's share price, which had been declining over the past couple of sessions following positive results from a pulmonary arterial hypertension (PAH) study conducted by Insmed. The study evaluated a prodrug formulation of UTHR's treprostinil, the active ingredient in its blockbuster Tyvaso products. Unlike Tyvaso, which requires multiple daily doses, Insmed's formulation allows for once-daily dosing. This drugmaker is expected to post quarterly earnings of $6.87 per share in its upcoming report, which represents a year-over-year change of +17.4%. Revenues are expected to be $796.42 million, up 11.4% from the year-ago quarter. While earnings and revenue growth expectations are important in evaluating the potential strength in a stock, empirical research shows a strong correlation between trends in earnings estimate revisions and near-term stock price movements. For United Therapeutics, the consensus EPS estimate for the quarter has been revised 0.7% higher over the last 30 days to the current level. And a positive trend in earnings estimate revision usually translates into price appreciation. So, make sure to keep an eye on UTHR going forward to see if this recent jump can turn into more strength down the road. The stock currently carries a Zacks Rank #3 (Hold). You can see the complete list of today's Zacks Rank #1 (Strong Buy) stocks here >>>> United Therapeutics is part of the Zacks Medical - Drugs industry. BioCryst Pharmaceuticals BCRX, another stock in the same industry, closed the last trading session 2% lower at $10.40. BCRX has returned 7.7% in the past month. BioCryst's consensus EPS estimate for the upcoming report has remained unchanged over the past month at $0.02. Compared to the company's year-ago EPS, this represents a change of +133.3%. BioCryst currently boasts a Zacks Rank of #2 (Buy). Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report United Therapeutics Corporation (UTHR) : Free Stock Analysis Report BioCryst Pharmaceuticals, Inc. (BCRX) : Free Stock Analysis Report This article originally published on Zacks Investment Research ( Zacks Investment Research Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
