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The Guardian
19 hours ago
- Health
- The Guardian
I spent my childhood in and out of hospital. At 19, I finally realised I had a terminal disease
Yvonne Hughes was 19, and attending the funeral of a friend with cystic fibrosis, when she realised: 'Oh shit, I'm going to die of this.' She had met him during shared hospital stays in childhood, and although Hughes had always known she had CF, she had never understood her illness as terminal until that day in 1992, when she stood at the back of the crowded chapel in Glasgow. For three days afterwards, she couldn't stop crying. 'I had a kind of meltdown. That's probably the first time I thought that this thing I had was going to kill me.' Over the next few months, Hughes, who was studying at the University of Glasgow, listened to her mum, dad and older sister chatting during family meals as if she was a ghost at the table. 'I pulled back from them. I deliberately didn't talk or include myself,' she says. 'I wanted them to get used to sitting and chatting without me, so that when I died, they wouldn't notice I wasn't there.' It's a harrowing responsibility for a teenager to take, but self-erasure must have felt like a way to pre-empt death, perhaps to resist it. When she was growing up, cystic fibrosis was considered 'a childhood disease' – because about half of those diagnosed did not survive their teens. A genetic condition in which the body creates thick, sticky mucus, it makes digestion difficult, damages lung function and can lead to respiratory failure. It affects about 160,000 people globally. Now 52, and enjoying what she calls a 'second chance' at life more than 30 years later, Hughes has emerged as a comedian. We are speaking on a video call before her one-hour show, Absolutely Riddled, which she is performing at the Edinburgh fringe, based on her experiences of living with the condition. 'I want to be true to myself and my story,' she says. Why does she think she survived when so many didn't? For most of her childhood, Hughes, who works as a community development worker in Renfrewshire, didn't regard herself as struggling for survival. Her parents didn't sit her down in childhood to explain her illness; she had been diagnosed at six weeks old. But there were hospital visits and tablets and eating often made her vomit. Gradually, she says, she 'put together those two words, cystic and fibrosis, with something that I had'. At school, she kept her illness hidden, taking her medication at home. She was popular; joined the Brownies, then Guides. 'I'm a very level-headed person, but I keep a lot in my mind. I remember when I was younger thinking: 'There's no point telling people about this because everyone is dealing with something. I'm nothing special.' I just got on with it.' Roughly one in every 2,500 people are born with cystic fibrosis in the UK, Australia and the US. Hughes's older sister does not have the illness and the family had no idea what it meant for their lives, or for Hughes herself. Only as she grew older did Hughes build a sense of the precariousness of her life. 'My mum said to me: 'We thought you were going to die, every day. We just didn't know.' It became their new normal to keep me alive.' If she got a chest infection, pleurisy or pneumonia, she would go into hospital, and over the years made friends on the CF ward, a fragile community. When the curtains were closed around a bed for a long time, Hughes and the other children knew not to go past. She reasoned with herself, to allay her fears: 'People were dying around me but I put it down to: 'Maybe they had a really bad infection, maybe they were worse than me.'' In childhood, she developed 'a lot of level-headed thought processes around why those people died'. She found solace in the Cystic Fibrosis Trust magazine, and dreamed of attending one of the advertised camps. 'Luckily, I didn't,' she says, because in the early 1990s, scientists discovered that the camps were a hotbed for the spread of bacteria, present in the lungs and phlegm of children with CF. Many cross-infected each other, some with fatal consequences. Did Hughes struggle to accept that sense of herself, as both vulnerable and a threat? 'Absolutely,' she says. Hospitals implemented a policy of segregation, according to bacteria carried. Hughes has the pseudomonas bacteria, and after her friend's funeral in 1992, she stopped seeing people with cystic fibrosis in case they had different bacteria or bugs that might lead to cross-infection. She has stayed in touch by phone with one old friend. 'We shared growing up in the hospital ward and I do love speaking to him.' But after that funeral, 'I became reckless,' she says. 'I thought: 'Well, life's for living. I'm just going to do what I want.' I didn't care very much for myself. I thought: 'What's the point?' I spiralled.' Her 20s and 30s passed in a blur of 'festivals, partying, travelling when I could, flying by the seat of my pants … ' She had hoped to meet someone, and to have children. 'I thought it would happen. And it never did.' In her 30s, her lung function got so low – 45%, then 36% – that she wouldn't have been able to sustain a pregnancy anyway. 'That was something I tried to grieve. But over the course of a year, I thought: 'I'd rather be alive.' My mantra became: 'I'd rather have a full and short life than a long and unhappy one.' These kinds of philosophical things got me through.' Hughes doesn't have a mantra now – 'other than trying to be funny'. The frequency of her performances range from three times a week to every few weeks, depending on her health needs. But even in her reckless phase, she embodied a stoicism, too. She worked throughout – at a call centre, a radio station, the CF Trust. 'I just had to keep going, pay my bills and mortgage.' Did she ever wonder: 'Why me?' She has had years of spitting out and swallowing mucus – 'constant, constant' – hankies everywhere, non-stop sterilising of stuff, endless medication and pain, unable to take the next breath for granted. As a child, when she went into hospital, there was a faint sense of privilege at being given Lucozade and new slippers, things her sister didn't get. But no one else in her family has the illness. Didn't she feel aggrieved? 'It's a difficult question,' she says. 'I've thought about 'Why me?' in a positive sense – that it was me because I could handle it. Or, I'm glad … because this has made me the way I am.' She has also thought, 'Why at all? Why did cystic fibrosis come into being? Why have this weird disease that just kind of ruins lives?' While Hughes survived childhood by reminding herself that she wasn't special, the differences between her life and others' sharpened as she entered her 40s. She became an aunt, and bore close witness to her peers' life transitions while she kept on being 'just Yvonne – the one that never reached any potential'. 'I couldn't have a career because I would always get ill. I never moved social class. I always remained working class.' Her dad was a welder, her mother a GP receptionist. 'Everything I did, I did myself. But it was day by day, week by week. There was never a plan. I always felt I could never get ahead of myself.' In 2018, aged 45, with deteriorating health, Hughes took redundancy from her job as public affairs officer at the CF Trust. Eating was difficult. Her weight hovered around 7 stone. She braced herself for the possibility of a lung transplant, but as her lung capacity dropped to 30%, she was deemed too ill for the waiting list. 'I was like: 'OK, that door's closed. At this point, there isn't anything else on the horizon to keep me alive.'' She completed an end-of-life form, and met the palliative care team. She thought: 'I'll see my days out with my parents, make memories and know I did well to get to 48.' Then, in 2020, the UK government granted access to a new drug, Kaftrio. Hughes had read about its worldwide trials. When the delivery driver knocked on the door, she told him: 'You're going to save my life.' At that point, her lung function was down to 26%. Within an hour or two of the first tablet, she started coughing. 'They call it the purge,' she says. There was so much mucus – dark, watery and horribly fascinating – she captured it in a cup, put a lid on it, and stowed it in a drawer in her bedroom. 'I kept that cup for a long time,' she says. Maybe she already knew it was a relic. The Kaftrio turned Hughes's life 'a whole 180, literally overnight'. There are side-effects – insomnia, weight gain, which have brought other challenges – but before long, she says, 'I could breathe again without coughing. I went back to work within the year. I could run, I could dance, I could speak, I could stand up straight and cook. I used to always be bent over, catching my breath. And then all of a sudden that was gone. It was a miracle.' Energised, she decided to enrol in an evening course. Acrylic painting, maybe, or playing the keyboard? But at the University of Strathclyde's Centre for Lifelong Learning, it was the flyer for comedy that caught her eye. 'I had always loved going to gigs. Something clicked and I enrolled.' She performed a five-minute set for the course finale – and immediately wanted to do it again. 'I started applying for clubs, Monkey Barrel and the Stand Comedy Club [both in Edinburgh]. I got Red Raw [the Stand's beginners' slot] and went from there. I want to change my life,' she says, 'and I am doing comedy to see if I can change my life.' Nearly four years ago, Hughes met her partner, Alan, online. Having spent a lifetime feeling unable 'to rely on a future', she has had to learn to picture one – and to override her old instinct to absent herself to mitigate later losses. Sometimes, this means catching herself in the act of 'pulling back' from Alan, and letting the pleasure she takes in his company teach her to quiet her mind. Life now is so different, it requires a conscious effort to remember how hard it was from one moment to the next. 'I used to breathe so shallowly that I had to take a – haa! – sharp intake of breath – to feel I was breathing,' she says. The sound punctuated even the simplest actions – after getting into a car, for instance, after reaching for her seatbelt, after pulling it across her, after fastening it. 'Now I can get in the car, pull the seatbelt over and go. I can walk and talk. I can laugh without wetting myself or going into a convulsion of coughing, pulling a muscle or breaking a rib,' she says. 'It is a horrible, horrible disease. It suffocates you. It takes every inch of your breath away. And now it is something I can live with and not die from. I'll probably live to get my pension.' Comedy has brought 'fun, joy and laughter' back into Hughes's life. But it has also given her something that nothing else has. 'I had never found anything for me in my life. I'd never married. I had no children. So I had no community. Nothing,' she says. 'There were people getting their careers and their lives sorted. Comedy was the one thing that was for me. And it still is. Just for me.' Yvonne Hughes: Absolutely Riddled is at Snug at Gilded Balloon Patter House, Edinburgh, until 15 August


DW
a day ago
- Politics
- DW
How Trump's trip split Scotland – DW – 07/29/2025
The US president has a soft spot for Scotland — but the feeling isn't mutual for most Scots. Trump's business-and-pleasure trip offered political wins for both sides. Will Scotland keep him at an arm's length? Donald Trump may be the most powerful member of Scotland's diaspora, but most people in his mother's country of birth did not view the US president's recent trip as the return of a prodigal son. As Trump touched down in Ayrshire late last week to begin a golfing holiday heavy on global geopolitics, Scotland's nationalist-leaning newspaper printed a front page that summed up how many here see him: "Convicted US felon to arrive in Scotland," it read. Anti-Trump protesters gathered under grey summer skies in Aberdeen on Saturday vented about the visit. "Deport Donald!" was scrawled on one cardboard placard. "Yer maw was an immigrant!" another sign read, adding some Scottish slang into the proverbial mudslinging. "Donald Trump does not represent the politics of the people of Scotland," demonstrator Alena Ivanova told DW. "He's not welcome here because he represents hate, and we support community and working together." This outright outrage at Trump's visit may be confined to opposition and activist circles, but Ivanona does have a broader point: Evidence shows the US president's politics don't chime with the majority of Scots. When asked how much they like him, Scots scored Trump an average of 1.76 out of 10. "Even those people who are more positive about him aren't going to be love-bombing him — and aren't expressing great affection for him," political scientist Chris Carman told DW. "Scots tend to see themselves as being more communitarian and somewhat more progressive," Carman, a professor at the University of Glasgow who crunched the polling numbers, explained. For now, the biggest political battle lines in Scotland — a nation of 5.5 million — are not between left and right. In fact, the most popular parties are both center-left, and instead public opinion is split on whether Scotland should divorce itself from the rest of the United Kingdom. The anti-Trump mood goes right to the top here. First Minister John Swinney, who heads up the devolved Scottish government in Edinburgh, publicly backed Trump rival Kamala Harris in last year's US elections. In February, Swinney accused Trump of promoting "ethnic cleansing" over his comments about Gaza. But a lack of enthusiasm from the public did little to dampen Trump's mood this week. He seemed right at home as he cut the ribbon on his third Scottish golf resort, which includes a course named after his mother Mary Anne McLeod, who left Scotland for New York aged 18. To this day, Trump has first cousins living in the country. "We love Scotland," a visibly upbeat US president said on Tuesday. He even extended a rare compliment to journalists here. "They're not fake news — today they're wonderful news," he said. This kind of trip, mixing the private with the political — and business with pleasure — is unusual for a sitting US president. By now, America's allies are accustomed to Trump's tendency to upend diplomatic norms, but the sight of a US leader playing host to UK and Scottish counterparts as guests on their own soil was still striking. Trump was in control, but they seemed happy to play along — and all three will go back to their capitals claiming diplomatic or economic wins. To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video UK prime minister Keir Starmer and Scotland's John Swinney both pressed Trump to use his influence to end the humanitarian catastrophe unfolding in Gaza, and Trump appeared to toughen his position on Russia — music to the ears of European allies. On a more personal level, Trump seemed sold on Scotland's Swinney, calling him a "terrific guy" before leaving on Tuesday. But Swinney was more cautious in his assessment, reflecting the political tightrope he is walking. Swinney steered clear of his past Trump-bashing, but also dodged repeated questions on whether he "liked" the US president. "He was pleasant company," Swinney told Scottish broadcaster STV on Tuesday. "I think my personal feelings about people are irrelevant. I've got a job to do," he added. That job includes trying to cushion the blow of US tariffs to Scotch whisky, one of the country's biggest exports. And some have been urging the first minister to drop the "grin and bear it" approach and embrace Trump to reap the possible rewards of the most powerful man in the world having a soft spot for Scotland. "I don't think we should expect all Scots to love Donald Trump. But we need to respect the position of president of the United States," businessman Allan Henderson told DW on Tuesday. "If he is prepared to invest in our country and employ people," he added, "then I'm sorry, I would get behind that." "We rely on goods like Scotch exports to the United States. The last thing you want to do is to put that industry into peril." Swinney told reporters on Tuesday that Trump had showed "willingness' to look at issues raised, including exempting whisky from US duties. No formal deal for Scotch was struck. Businessman Allan Henderson's home region of Aberdeenshire is no stranger to Trump-driven controversy. The US president was quick to bring up his age-old Aberdonian foe during this latest visit. For more than a decade, Trump has been railing against wind turbines that generate renewable energy near Aberdeen and elsewhere. He even unsuccessfully sued the Scottish government to try and halt construction of a wind farm near his golf course — a case that made it all the way to the UK Supreme Court. "Get rid of the windmills and bring back the oil," was Trump's message to Scotland before embarking on his most recent trip. As Trump winds up his five-day working holiday in Scotland, it's likely that his stake in Scottish politics may long outlive his presidency. After all, his business interests will continue to be bound by laws laid down in Edinburgh and London. Political scientist Chris Carman said it was not simply "a one-way street" whereby Scottish First Minister John Swinney is scrambling to make it positive. "Both leaders have an interest in trying to make sure that there's that positive dialogue between the Trump Organization and the Scottish government." "Donald Trump is perfectly willing to leverage both his soft and hard power in pursuing his financial interests and protecting his financial interests in Scotland," Carman told DW.. And that leaves at least one certainty for Scotland in a world increasingly defined by the stroke of an unpredictable presidential pen. As Carman put it: "Donald Trump is going to be a feature in Scottish politics."


The Sun
2 days ago
- Entertainment
- The Sun
Lottery experts' 9 top tips for winning £131m Euromillions jackpot TONIGHT – plus the exact time to buy your ticket
EVERYONE wants to win the lottery - but what if we told you the secret to scooping the giant £131million Euromillions jackpot tonight? Lottery experts have exclusively shared their ultimate tips with Sun readers on how to boost your chances of walking away with the entire mega prize up for grabs. 2 Maths whizz David Hodge, a lecturer in statistics and data analytics at the University of Glasgow, and Simon Horne, from The National Lottery operator Allwyn UK, share their winning formulas. Plus Lottery Guy, who has been dishing out winning tips on his blog since 2004, shares how he helps players win big. Millions of us buy a Euromillions ticket each week, which means there is fierce competition for the top £131million jackpot prize up for grabs tonight. There have been huge jackpots available recently - a record-breaking £208million prize that was won by a lucky Irish ticket holder last month. You pick five numbers from 1-50 and two lucky stars from 1-12, or you can choose a lucky dip - which is when the numbers are randomly selected for you. If you're lucky enough to have the winning ticket tonight, you'll instantly become richer than the likes of superstars Daniel Radcliffe, Dua Lipa and tennis ace Andy Murray. From picking your lucky numbers to joining a syndicate, there's a heap of practical ways to boost your chances of getting richer overnight. Of course, the only real way of increasing your chances of winning is to buy more tickets. Make sure you gamble responsibly. Only gamble with money you can afford to lose, and set a money limit before playing. If you need advice, visit or Monitor your numbers Do you have a set of numbers you stick to religiously, but have noticed they just aren't working for you? Keep an eye on how often your numbers are being drawn, and if they're not coming up as often as you would like, you can try a different tactic. The National Lottery app stores all your tickets from draws you have entered. The app is free to download from either the App Store on iPhone, or the Google Play Store on Android devices. That means you can go back in and check your most profitable numbers. Make a spreadsheet of how often your lucky numbers are being drawn, and every three months, see whether it's worth keeping them or ditching them for alternatives. Timing matters Timing matters when it comes to buying your ticket, said Simon. If you leave it to the last minute, then there's a risk that you run out of time to buy yours. You need to buy your ticket before 7:30pm tonight - otherwise you'll miss out. "My main advice is not to leave it too late - don't rush into the newsagents or load up your app at 7:25pm," he said. "You might not be able to upload money onto your online account, or buy your ticket, in time, and you could miss the draw." Avoid birthday numbers You must pick five main numbers between 1-50 for your EuroMillions ticket and two "lucky star" numbers from 1-12. It may be tempting to pick your and your loved one's birthday dates as your main numbers with the hope they bring you luck. But Lottery Guy said it's best to avoid this tactic. This is because there will be lots of people picking birthday dates too. Birthday dates are numbers between 1-31. There's a greater chance of having to split the pot between other players if you're lucky enough to hold the winning ticket. He says: "Avoiding these numbers doesn't increase your chance of winning, but if you do win, you're much less likely to split the prize with other winners. Adrian Bayford became one of the UK's biggest Euromillions winners in 2012 when he scooped the £148.6 million jackpot. The former postman celebrated his gigantic win by ordering Domino's pizza for him and his then-wife, Gillian. Speaking about the win at the time, Gillian said: " "I checked the numbers on my phone, the TV, the internet — and we just looked at each other and giggled." Adrian and his wife divorced just 15 months after their win, with Gillian later saying the money had come between her and her family. Adrian has splashed his winnings on various ventures since. He purchased a Grade II listed estate, Horseheath Lodge, in Cambridgeshire for £6.5million, complete with luxurious amenities. In 2020, he bought two estates in Scotland — he paid £1.1million for one in Blairgowrie, Perthshire, and days later splashed out 1.35million on another plush pad just 12 miles away. He has also previously run small businesses on his estate, including a record shop, a pub, and even organised a music festival dubbed a 'mini Glastonbury' on his Cambridge Estate since 2017. In 2023, he began renting out a cottage on his property as an Airbnb for £110 a night, and the following year began renting out a farmhouse on the 189-acre estate for extra cash. Adrian planted grape vines in 2024, aiming to produce sparkling wine. His vineyard is roughly the size of six football pitches. Together with his fiancée Tracey Biles, he has been growing his own food in a new kitchen garden, as well as creating a large carp pond and raising goats and pigs. Which day to play You have to be in it to win it, so if you want the chance of scooping a jackpot, you must buy a ticket. But certain days are better than others to play. Lottery Guy said Tuesday is actually the best day to buy a ticket instead of Friday. He said: "With EuroMillions, Friday is the much more popular day, so you've got more competition on a Friday. "Consider focusing on the Tuesday draw if you want to keep more of that jackpot for yourself." Should you buy more tickets? YOU'VE got to be in it to win it. Every time you buy a ticket the odds of winning increase. But WARNING - only spend what you can afford. At the end of the day, it's down to luck. This is why some people prefer to be part of a syndicate, where multiple tickets are bought. While this means you'll have to share the pot, the odds become more favourable each ticket you buy. Pick 'boring' numbers Probability pro David Hodge said the key to playing the Euromillions is to pick numbers that other players won't. That's because, statistically, each number has an equal chance of being drawn, so there is no such thing as a "lucky" number. He tells Sun money: "Any prize could be theoretically shared, so you will want to be the only one who wins if you do win. "So that means you need your numbers not to be other people's numbers. That means avoiding number patterns." Picking "boring numbers" - those which do not stand out in any way - is a good tactic, he said. These are numbers that have been drawn out an average number of times in the Euromillions draws. So 37, 24, and 13, which has been drawn a mediocre 91 times, could be a good option, as well as 32, which has been drawn 90 times. "Pick the ones that look boring and that people won't be interested in," David adds. Never choose "overdue" numbers Likewise, don't pick "overdue" numbers - which are the numbers drawn the least number of times in Euromillions games. David says picking these numbers is a common tactic players follow. Again, that means that if you win, there's a greater chance of splitting your winnings with other people. "People might look for numbers that haven't come up very often, because they think they're due to come up soon," said David. "This is nonsense, because past numbers have no effect on what's going to happen in the future." Avoid picking "weird" combinations You might be tempted to pick "weird" number combinations thinking that no one else will. That's sequences like: 1,2,3,4,5 5,10,15,20,25 2,4,6,8,10 But picking "weird" combinations is a surprisingly common tactic, says David. "If you think something is a weird combination, it's likely that other people will think it's weird too, and will likely pick that combination too. "That's because your brain holds onto anything that fits some kind of pattern." The key is to avoid number patterns, he says. A lucky dip really could be lucky What better way of avoiding number patterns than to pick a lucky dip? This is when the numbers are randomly selected for you by a computer when you buy a ticket at the till. David says: "Humans are notoriously bad at picking random numbers. "So it's likely that your attempt at picking five truly random numbers will probably fail. "The key is not to be biased towards any number." Join a syndicate A lottery syndicate is when a group of people put money into a pot for lottery tickets. There will be one person in charge - called the syndicate manager - who is in charge of buying tickets and sharing out any winnings out among the group. The syndicate manager will need to register the group with the National Lottery and list themselves as the person in charge. Playing with a group could be a good way of boosting your chances of winning, as Simon, from The National Lottery operator Allwyn UK, explains. He says: "If you join a syndicate of 10 people, then there's 10 tickets and 10 chances of winning, so there's clearly a greater chance of winning compared to if you just bought your own ticket. Simon advises players in a syndicate to draw up a list of terms and conditions that they all must agree to and sign. He adds: "If there's any confusion or complications down the line, then you can refer back to the agreement and then everyone knows where they stand. Of course, the biggest downside to a syndicate is that you will have to split the pot among the whole group equally. So if you played in a group of 10 people and you won the £131million jackpot, each person would walk away with £13.1 million. Of course, that's still big winnings to walk away with, but it's certainly something to consider.


Daily Mirror
2 days ago
- Health
- Daily Mirror
Breakthrough in breast cancer research could stop the disease from spreading
The discovery offers new hope in the fight against breast cancer, as it could detect and stop the spread of the disease before it becomes incurable Scientists have achieved a significant breakthrough in the battle against breast cancer by dismantling the very components that enable the deadly disease to metastasise. Researchers have discovered that cancer alters the metabolism of certain immune cells, causing them to release a metabolite known as uracil, which aids in constructing a 'scaffold' within distant organs, facilitating the growth of secondary tumours. By inhibiting the enzyme uridine phosphorylase-1 (UPP1), responsible for producing uracil, scientists were able to prevent this 'scaffold' from forming in mice and rejuvenated the immune system's capacity to eliminate secondary cancer cells, thereby thwarting metastasis. This groundbreaking work was carried out in the laboratories of Professor Jim Norman and Professor Karen Blyth at the Cancer Research UK Scotland Institute and the University of Glasgow. This discovery paves the way for potentially potent new methods to combat cancer – identifying uracil in the bloodstream could signal early indications of cancer metastasis, while impeding UPP1 with medication could halt its progression before it even begins. The study's lead author, Dr Cassie Clarke, from the Cancer Research UK Scotland Institute and University of Glasgow, said: "This study represents a major shift in how we think about preventing the spread of breast cancer. By targeting these metabolic changes as early as possible we could stop the cancer progressing and save lives." Published in Embo Reports, the research indicates that crucial metabolic alterations take place prior to the dissemination of cancer, presenting an essential opportunity for intervention. Identifying these alterations at an early stage could enable treatments to prevent cancer cells from migrating throughout the body and establishing tumours in different locations. Dr Catherine Elliott, Cancer Research UK's director of research, explained: "Discoveries in cancer research have made huge strides in making breast cancer a far more treatable disease than ever before. However, metastasis - when cancer spreads - is a major factor in breast cancer becoming harder to treat especially if the cancer returns months or even many years later. "This discovery gives us new hope for detecting and stopping metastasis early and ensuring people have many more years with their families and loved ones." With approximately 56,800 people receiving a breast cancer diagnosis in the United Kingdom annually and roughly 11,300 people dying from it each year, discovering innovative approaches to combat it remains crucial. Due to research breakthroughs, breast cancer has evolved into a significantly more manageable illness, yet when it metastasises to different parts of the body, effective control becomes increasingly challenging. Comprehending the mechanisms behind breast cancer's spread is essential to preventing the disease from becoming uncontrollable with existing treatments. The research team is now delving deeper into precisely how UPP1 alters immune cell behaviour, examining the function of immune cell metabolism in early breast cancer development, and evaluating the potential of medications that inhibit immune cell metabolism to prevent cancer onset. Simon Vincent, the chief scientific officer at Breast Cancer Now, said: "This is an exciting piece of joint research that expands our understanding of how secondary breast cancer develops. "The researchers discovered that high levels of a protein called UPP1 may make some cancers, including breast cancer, more likely to spread to other parts of the body, where the disease becomes incurable. "In mice, targeting the UPP1 protein before secondary breast cancer developed led to fewer secondary breast tumours and a boosted immune response in the lungs. "Now we need more research to see if this new insight can be turned into new drugs that stop secondary breast cancer, and potentially other secondary cancers, in their tracks. With around 61,000 people living with secondary breast cancer in the UK, research like this is vital."


Time of India
2 days ago
- Business
- Time of India
University of Glasgow invites applications for its MBA scholarship 2025: How to apply, eligibility, exam requirements, and official website details
University of Glasgow opens MBA scholarship 2025 applications: How to apply, eligibility, and IELTS requirements University of Glasgow MBA scholarship 2025: The University of Glasgow is now inviting applications for its MBA Scholarship for the September 2025 intake. The scholarship is designed for high-achieving, self-funded candidates globally and provides both full and partial tuition fee waivers. The Glasgow MBA Scholarship supports the university's commitment to academic excellence and its values of diversity, equality, and inclusion. Candidates must first apply for the MBA (Master of Business Administration) programme and receive an offer before submitting a scholarship application. Scholarship categories and coverage The MBA Scholarship includes a small number of full tuition scholarships, a wider selection of partial tuition fee waivers covering up to 50% of the total fee, and a targeted full-fee scholarship for an outstanding female applicant. The women-specific award is offered in partnership with the 30% Club, a global campaign promoting gender diversity in business leadership. Applicants must be self-funded, as the scholarship cannot be combined with other discounts or external sponsorships, except for the University of Glasgow's Alumni Discount. If a student qualifies for multiple scholarships, only the higher-value award will apply. Eligibility criteria for applicants To be eligible for the scholarship, candidates must meet the following criteria: • A strong academic background, typically a first-class honours degree or equivalent • A demonstrated record of professional achievement • Completion of the MBA interview stage • An offer to join the MBA programme (unconditional or conditional only upon meeting English language requirements such as IELTS) • Financial need may also be considered Note: Only applicants who have already submitted their MBA application are eligible to apply for the scholarship. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Elegant New Scooters For Seniors In 2024: The Prices May Surprise You Mobility Scooter | Search Ads Learn More Undo Application timeline and review process There is no fixed deadline for the scholarship application. However, the university advises early submission due to limited availability of funds and the rolling basis of awards. Scholarship applications are reviewed following the candidate's MBA interview, and decisions are typically communicated within five working days. Open to global candidates The Glasgow MBA Scholarship is open to applicants from numerous countries and regions across Africa, Asia, Europe, the Americas, and Oceania. Some eligible countries include India, Nigeria, the United States, United Arab Emirates, South Africa, and Australia. The funding applies exclusively to the MBA programme commencing in September 2025. How to apply through the official website Applicants must follow these steps to complete the scholarship application process: Step 1: Visit the official website: Step 2: Apply to the MBA programme using the university's online application form Step 3: Complete the MBA interview process and obtain an offer (unconditional or conditional only upon IELTS) Step 4: Download and complete the Glasgow MBA Scholarship Application Form Step 5: Upload the completed scholarship form via the Applicant Self-Service portal Contact information for queries • For guidance on the MBA programme and admissions, candidates may email: business-mba-recruitment@ • For questions related to scholarship eligibility, applicants should contact: scholarships@ Scholarship terms and additional notes The scholarship cannot be combined with other University of Glasgow internal or external sponsorships, with the exception of the Alumni Discount. If more than one scholarship is awarded, the one of lower value will be removed from the student's record. This scholarship opportunity is part of the university's broader strategy to support highly qualified, self-funded students from diverse backgrounds across the world. TOI Education is on WhatsApp now. Follow us here . Ready to navigate global policies? Secure your overseas future. Get expert guidance now!