Latest news with #Welter
Chicago Tribune
3 days ago
- Health
- Chicago Tribune
Rush now offers a blood test to help detect more than 50 types of cancer, as other health systems remain wary
Jack Welter didn't feel sick when he agreed to take a new blood test that looks for multiple types of cancer. But, approaching 60, he thought it couldn't hurt. To his surprise, the test came back positive. Welter then underwent multiple rounds of follow-up tests, and ultimately, doctors found cancer in his throat. The now 61-year-old Elkhart, Indiana, resident endured radiation and chemotherapy in 2023 and is now cancer-free. 'Without that test, I still would have had (cancer), obviously, but it might not have appeared for another year or more,' said Welter, who is expecting his first grandchild. 'Early detection is the key to success.' In recent years, the blood test, called Galleri, and others like it, have been gaining momentum among doctors who use them to help detect cancers that otherwise might go unnoticed until patients become ill. Now, at least one local health system, Rush University System for Health, has decided to start offering Galleri to patients widely in hopes of finding cancer early, when it's easier to treat. The test has not yet been approved by the U.S. Food and Drug Administration and is not covered by most health insurance plans. At Rush, it will cost most people $749 out-of-pocket. Providers at other local health systems have expressed wariness about offering the test broadly at this point, given those concerns and others. But Rush leaders felt it was important to move forward with the test, given its potential life-changing benefits for patients and because of its performance in clinical trials, said Dr. Lisa Stempel, director of the high-risk cancer screening program at Rush. 'The goal of all screening is to find cancer early when we can treat it,' said Stempel, who noted that 1 in 3 people will get cancer in their lifetimes. 'It's such a simple test in the fact that it can find so many cancers and the fact that it can find it in early stages is what's extremely exciting to me.' The test works by identifying DNA in the bloodstream that's shed by cancer cells. It can detect a cancer signal shared by more than 50 types of cancer, and it can also reveal roughly where in the body the cancer might be. A positive result is not the same as a diagnosis. If a patient gets a positive result, the patient must undergo additional testing, such as CT scans or PET scans, to help assess if they really have cancer. There's a 43% chance that a positive test result will be cancer, according to a study from Grail, the company that makes the Galleri test. The test has a false positive rate of 0.5% among patients who don't have cancer, meaning about 1 out of every 200 people who take the test and don't have cancer might still get a positive result. The test is only available by prescription, and it's recommended annually by Grail for people at higher risk of cancer, such as those ages 50 and older. Rush is also offering it to younger adults with risk factors such as a family history of cancer, smoking, diabetes or obesity. If a patient gets a positive result but doctors can't find any cancer, Grail offers a second test to the patient free of charge. That's what happened to Welter, the Indiana patient who had throat cancer. The first time he took the test, it came back positive for cancer somewhere between his chest and head, he said. But more traditional follow-up tests didn't turn up any cancer. He then took a second, free Galleri test about six months later and, again, it was positive. He underwent more testing, and the second time around, doctors found the cancer. 'At that point in time it was so small they really couldn't pinpoint it,' Welter said of doctors' efforts to find the cancer after his first Galleri test. Welter has been speaking to doctors at Rush about his experience in recent months as part of their training to offer the tests to patients widely. Welter said he hasn't been paid by Grail nor Rush. 'To me it's amazing the test could actually find something like that,' Welter said. Not everyone, however, is as gung-ho about the test. Though health systems in other parts of the U.S. are also offering Galleri, some Chicago-area health systems and providers say they don't believe the test is ready for prime time. Northwestern Medicine is not systematically offering the Galleri test at this point, with a spokesperson saying, 'The technology isn't sufficiently sensitive and specific enough for us to use this as a screening tool at this time.' Feighanne Hathaway, a genetic counselor at UChicago Medicine, said she also has a number of concerns. For one, she worries that the out-of-pocket cost creates more disparities in health care. She also worries that the test may be less adept at picking up signals for early-stage cancers than later stage ones, raising questions about its usefulness and value. A Grail study found that 48% of confirmed cancers detected by Galleri were stages 1 or 2, and that adding Galleri to standard-of-care screening about doubled the number of cancers detected. Hathaway also fears that if a patient gets a negative test result, they may think they can forgo screenings such as mammograms and colonoscopies. Rush and Grail caution that the test is not meant to replace routine screenings. Largely, though, she's concerned that the test is not yet approved by the FDA. Hathaway said she likes the idea of the test, but, 'I just don't think we're there yet.' 'I think more research needs to be done before we start offering it,' Hathaway said. So far, more than 380,000 people are or already have participated in studies of Galleri, according to Rush. That includes a recently completed trial with 140,000 participants in the United Kingdom. The company is also sponsoring a clinical trial that's now seeking to enroll an additional 50,000 Medicare beneficiaries to test whether Galleri can help find cancer early and decrease the number of late-stage cancer diagnoses. Though Galleri is not approved by the FDA, Grail said it has been granted breakthrough device designation by the agency, which is meant to speed up development and review of devices that can more effectively treat or diagnose life-threatening and debilitating conditions. The company expects to finish submitting information to the FDA next year for premarket approval. 'Now, for the first time we've got breakthrough technology that can find cancer in adults who have no idea they have cancer, they have no symptoms, there's no suspicion of cancer, and we can look for more than those five cancers,' said Dr. Joshua Ofman, president of Grail, referring to the cancers that now have recommended screening tools, such as mammograms for breast cancer and colonoscopies for colorectal cancer. 'We can look for all the other cancers that are taking people's lives, because when you can find cancer early that is your best chance to cure it,' Ofman. Many patients feel the same way. Peter Crowell, 65 of Bucktown, was among the first group of Rush patients to sign up this month to be tested. After his primary care doctor mentioned it, Crowell made an appointment to get his blood drawn. 'He asked me if I was interested, given my history, so I said, 'Yeah,'' Crowell said, noting he has a family history of cancer. 'It's just something I think I'd rather be proactive about.' Of course, Crowell wishes insurance would pay for it, but he's willing to shell out the $749 for the test. He said he'll likely pay for it using a flexible spending account. 'If I can find out if I have any of those markers, then it will be worth it,' Crowell said. Maggie Hornung, a nurse practitioner at Rush, recently had her blood drawn for the test. It takes about three to four weeks to get results. 'I obviously was excited as a provider to start offering this and working on this but as a patient I absolutely wanted to proceed,' said Hornung, 58. She wanted to take the test because she's had family members with cancer, and because of what she's seen in her work with patients in the high-risk breast cancer clinic at Rush. 'To me, $749 is a small cost compared to what things could be,' Hornung said.
7NEWS
05-06-2025
- Sport
- 7NEWS
El Soleado facing rare task in comeback from throat surgery
It is rare these days to find a horse being asked to carry 64.5kg in a race at Flemington. But that is what the Robbie Laing-trained El Soleado has in the VRC Country Race Sprint (1200m) on Saturday, although that weight is being offset by the 3kg claim of Sheridan Clarke. Laing is old-school and remembers growing up when horses like Alcatraz and Samson were carrying huge weights in races at his favourite tracks like Sandown and Caulfield. El Soleado is returning to racing having undergone tieback surgery on a throat condition but has pleased Laing in his three jump-outs, his most recent when successful at Cranbourne on May 26. 'He's got a run somewhere,' Laing said. 'It's a beautiful track and Sheridan Clarke is going to claim 3 kilos off him, so he comes in with 61-½ kilos and it's not like the bottom weights have 48 kilos like they used to years ago when there were massive differences from the top to the bottom weight.' A search through the Racing And Sports database, the most recent horse to have been asked to carry more than 64.5kg in a flat race at Flemington was Paris Lane in a Welter in February 1996, when he was allotted 68.5kg and was ridden by a then 2.5kg claiming apprentice Craig Williams. El Soleado hasn't raced since finishing ninth at Sandown last September after which it was discovered the gelding had a throat ailment. The rising six-year-old had a consistent summer – autumn campaign in 2024 and Laing was looking forward to last year's spring with El Soleado. 'His throat went all of a sudden,' Laing said. 'He had two runs on soft ground in Listed grade, and we were happy with him and then we took him to Sandown and backed him. 'Patrick Moloney rode him and said he didn't run on and made a hell of a noise. 'They scoped him, he was perfect, so we galloped him, he made a noise, then next time we galloped we put a dynamic scope on him. 'Halfway through the gallop, he couldn't breathe, so that's when we decided to send him off for surgery and give him a good break.' Having thought El Soleado would stretch out to 2400m, now Laing is thinking 1600m to 2000m might be more the gelding's trip. 'His galloping ability, his trials have been super, his action is good, he looks super,' Laing said. 'He might be a Toorak Handicap horse, or there may be a nice 1800-metre race or one over 2000 metres over the Carnival that may be his goal. 'But we'll keep him rolling along slowly after he runs on Saturday.'
Yahoo
02-05-2025
- Business
- Yahoo
Sask. shows signs of post-election western alienation, but many seem willing to give Carney a chance
With the federal election a few days behind us, western alienation is already creeping into the political discussion in Saskatchewan. Premier Scott Moe posted a video on social media Tuesday vowing to work with Prime Minister Mark Carney and the federal Liberals, but the post garnered backlash and calls for western separation from some Saskatchewan people. WATCH | CBC talked to people on the streets of Saskatoon on Wednesday to see if these sentiments were shared by all. Some people agreed that the Prairies have been undervalued. "Alberta's got a lot of oil and Saskatchewan's got a lot of wheat and agriculture. Those are critical to the country both domestically and internationally," Rob Soze said. "It seems like those provinces are kind of forgotten about in the grand scheme of things." But most of the people CBC spoke to seemed more willing to give the new Liberal government a chance. "We have a different Liberal government with different leadership who is kind of solid, and he's standing up to Trump," Dave Boykochukski said. "I think that's what Canada wants right now." Jeremy Welter, who farms canola in west-central Saskatchewan, agreed that the Liberal government seems to cater more to eastern provinces. "There were some things that happened where people out west were to a greater or lesser extent overlooked, and I think agriculture is certainly one of the biggest ones," Welter said. Welter is among many farmers hit hard by canola tariffs. He said it feels like the federal government may be putting more effort into fighting for the auto industry than the agriculture industry. Despite what he may have seen in the past, Welter said he's cautiously optimistic the Carney government is negotiating these tariffs behind closed doors. He just hopes more of an emphasis is placed on the importance of Prairie exports. "We don't have a national plan for our export commodities," Welter said. "Regardless of if we're talking about canola or wheat or steel, if we don't have a plan to get our commodities out to the market and out to the rest of the world, the value of us producing them very quickly evaporates." Welter went on to say that, financially and socially, separating the west from the rest of Canada would do more harm than good. As the discourse around separation continues in Alberta and Saskatchewan, it's not clear whether some people are simply looking for a place to vent their frustrations or actually seeking real change. Loleen Berdahl, a professor of political studies at the University of Saskatchewan, said that while the separatist movement has always existed in Western Canada, it has ramped up in recent years. Berdahl said that's partly due to rhetoric from Alberta Premier Danielle Smith and a lack of Saskatchewan voices in the governing federal party. "The lack of strong provincial and regional voices in the federal cabinet in federal policymaking can be an issue," Berdahl said. "In the last Trudeau liberal government there was no representation from Saskatchewan, because all the MPs were Conservative."
CBC
01-05-2025
- Business
- CBC
Sask. shows signs of post-election western alienation, but many seem willing to give Carney a chance
With the federal election a few days behind us, western alienation is already creeping into the political discussion in Saskatchewan. Premier Scott Moe posted a video on social media Tuesday vowing to work with Prime Minister Mark Carney and the federal Liberals, but the post garnered backlash and calls for western separation from some Saskatchewan people. CBC talked to people on the streets of Saskatoon on Wednesday to see if these sentiments were shared by all. Some people agreed that the Prairies have been undervalued. "Alberta's got a lot of oil and Saskatchewan's got a lot of wheat and agriculture. Those are critical to the country both domestically and internationally," Rob Soze said. "It seems like those provinces are kind of forgotten about in the grand scheme of things." But most of the people CBC spoke to seemed more willing to give the new Liberal government a chance. "We have a different Liberal government with different leadership who is kind of solid, and he's standing up to Trump," Dave Boykochukski said. "I think that's what Canada wants right now." WATCH | Do Sask. voters feel alienated from Eastern Canada after the federal election?: Do Sask. voters feel alienated from Eastern Canada after the federal election? 10 hours ago Duration 2:25 Do farmers feel valued nationally? Jeremy Welter, who farms canola in west-central Saskatchewan, agreed that the Liberal government seems to cater more to eastern provinces. "There were some things that happened where people out west were to a greater or lesser extent overlooked, and I think agriculture is certainly one of the biggest ones," Welter said. Welter is among many farmers hit hard by canola tariffs. He said it feels like the federal government may be putting more effort into fighting for the auto industry than the agriculture industry. Despite what he may have seen in the past, Welter said he's cautiously optimistic the Carney government is negotiating these tariffs behind closed doors. He just hopes more of an emphasis is placed on the importance of Prairie exports. "We don't have a national plan for our export commodities," Welter said. "Regardless of if we're talking about canola or wheat or steel, if we don't have a plan to get our commodities out to the market and out to the rest of the world, the value of us producing them very quickly evaporates." Welter went on to say that, financially and socially, separating the west from the rest of Canada would do more harm than good. As the discourse around separation continues in Alberta and Saskatchewan, it's not clear whether some people are simply looking for a place to vent their frustrations or actually seeking real change. Loleen Berdahl, a professor of political studies at the University of Saskatchewan, said that while the separatist movement has always existed in Western Canada, it has ramped up in recent years. Berdahl said that's partly due to rhetoric from Alberta Premier Danielle Smith and a lack of Saskatchewan voices in the governing federal party. "The lack of strong provincial and regional voices in the federal cabinet in federal policymaking can be an issue," Berdahl said. "In the last Trudeau liberal government there was no representation from Saskatchewan, because all the MPs were Conservative."
