Latest news with #WuhanUniversity
Time of India
29-06-2025
- Health
- Time of India
Parkinson's doesn't start in the brain? Shocking new study reveals the real origin
Image credits: Getty Images Parkinson's disease (PD) is the second-most neurodegenerative disorder in the United States. According to the National Institute of Neurological Disorders and Stroke, as many as 1 million Americans have Parkinson's Disease. Until now it was believed that Parkinson's disease begins with a gradual loss of nerve cells in the brain, particularly those producing dopamine, a neurotransmitter vital for movement. This leads to a decline in dopamine levels leading to symptoms such as tremors, stiffness and slow movement. Now, a new study published in Nature Neuroscience, suggests that the disease actually begins from a shocking body part- the kidneys. The team of researchers from Wuhan University in China performed the study primarily focused on the alpha-synuclein (a-Syn) protein, which is closely associated with Parkinson's. When the production of this protein becomes uneven, it creates clumps of misfolded proteins that interfere with brain function. As per the research, the clumps of this protein can develop in the kidneys as well and thus the researchers are of the belief that these abnormal proteins might actually travel from the kidneys to the brain, triggering the disease. "We demonstrate that the kidney is a peripheral organ that serves as an origin of pathological α-Syn," wrote the researchers in the published paper. The shocking study Image credits: Getty Images To carry out the study, the team ran multiple tests to analyse the behaviour of the protein in genetically engineered mice and human tissue that included samples from people with Parkinson's disease and chronic kidney disease. The team found abnormal a-Syn growth in the kidneys of 10 out of 11 people with Parkinson's and other types of dementia related to Lewy bodies. In another sample batch, similar protein malfunctions were found in 17 out of 20 patients with chronic kidney disease, even though these people had no signs of neurological disorders. In animals, mice with healthy kidneys cleared out injected a-Syn clumps, but mice whose kidneys weren't functioning faced protein built-ups that eventually spread to the brain. The study also analysed the fact that these proteins move through the blood and if they are reduced in the blood, the damage to the brain can be decreased. This point needs to be noted as an inspiration for new strategies of treatment.
Yahoo
29-06-2025
- Health
- Yahoo
Parkinson's Disease Might Not Start in The Brain, Study Finds
Parkinson's disease is traditionally associated with neurological damage in the brain, brought on by a drastic drop in dopamine production, but a new study suggests it could get started in an unexpected part of the body: the kidneys. Led by a team from Wuhan University in China, the study is primarily concerned with the alpha-synuclein (α-Syn) protein, which is closely associated with Parkinson's. When production goes awry and creates clumps of misfolded proteins, it interferes with brain function. The key discovery here is that α-Syn clumps can build up in the kidneys, as well as the brain. The researchers think these abnormal proteins might actually travel from the kidneys to the brain, possibly playing a part in triggering the disease. "We demonstrate that the kidney is a peripheral organ that serves as an origin of pathological α-Syn," write the researchers in their published paper. There's a lot to dig into here. The research team ran multiple tests, looking at the behavior of α-Syn in genetically engineered mice, as well as analyzing human tissue – including samples from people with Parkinson's disease and chronic kidney disease. The team found abnormal α-Syn growth in the kidneys of 10 out of 11 people with Parkinson's and other types of dementia related to Lewy bodies (a commonly seen type of α-Syn protein clumping). That wasn't all: in another sample batch, similar protein malfunctions were found in 17 out of 20 patients with chronic kidney disease, even though these people had no signs of neurological disorders. This is more evidence that the kidneys are where these harmful proteins begin to gather, before brain damage begins. The animal tests backed up these hypotheses. Mice with healthy kidneys cleared out injected α-Syn clumps, but in mice with kidneys that weren't functioning, the proteins built up and eventually spread to the brain. In further tests where the nerves between the brain and kidneys were cut, this spread didn't happen. As α-Syn proteins can also move through the blood, the researchers tested this too. They found that a reduction in α-Syn in the blood also meant less damage to the brain, which means this is another consideration to bear in mind. There are some limitations to this study. The number of people that tissue samples were taken from was relatively small, and while mice make decent stand-ins for humans in scientific research, there's no guarantee that the exact same processes observed in the animals are happening in people. However, there are lots of interesting findings here that can be explored further, which could eventually aid in the development of new treatments for Parkinson's and other related neurological disorders. The likelihood is that Parkinson's (in a similar way to Alzheimer's disease) is actually triggered in a variety of ways and through a variety of risk factors. For example, previous studies have also suggested it could get started in the gut – and now it seems the kidneys could be connected in a similar way. "Removal of α-Syn from the blood may hinder the progression of Parkinson's disease, providing new strategies for therapeutic management of Lewy body diseases," write the researchers. The research has been published in Nature Neuroscience. These Common Drugs Can Make Coping With Heat Even Harder Tinnitus Seems Somehow Linked to a Crucial Bodily Function Your Ear Wax Might Hold Clues to Early Parkinson's, Study Finds
Yahoo
19-06-2025
- Business
- Yahoo
The Economics and Management School of Wuhan University Has Been Re-Accredited by EQUIS for the Highest Five-Year Period
Wuhan, China--(Newsfile Corp. - June 19, 2025) - Recently, the European Foundation for Management Development (EFMD) released a formal letter informing that the Economics and Management School (EMS) of Wuhan University (WHU) has successfully gained the five-year re-accreditation of EQUIS (EFMD Quality Improvement System). This is the first time that the EMS has been accredited by EQUIS' highest honor, a five-year period, following its first accreditation in 2016. This figure displays the EQUIS Five-Year Accreditation Certificate first awarded to the School of Economics and Management, Wuhan University. To view an enhanced version of this graphic, please visit: In March this year, an EQUIS peer review team, led by Professor Peter Møllgaard (President, Copenhagen Business School, Denmark), conducted a three-day comprehensive on-site evaluation at WHU. The panel included Professor Caitlin Byrne (Pro Vice Chancellor, Griffith University, Australia), Professor Wei Gu (Dean, School of Economics and Management, University of Science and Technology Beijing), and Mr. Jacques Delplancq (Former Deputy General Manager, IBM France). The practice of EMS was thoroughly inspected through in-depth exchanges with Huang Taiyan (Secretary, Party Committee, WHU), Zhu Deyou (Vice President, WHU), Yuan Yufeng (Vice President, WHU), heads of relevant departments, and representatives of faculty members, students, alumni, corporate partners, etc. Cannot view this video? Visit: EQUIS accreditation is known for its rigorous evaluation process and excellent quality requirements. Since initiating its international accreditation journey in 2010, EMS has successively earned three top-notch accreditations: AMBA, EQUIS, and AACSB. Hashtag: #TheEconomicsandManagementSchoolofWuhanUniversity The issuer is solely responsible for the content of this announcement. Media Contact: PR Contact Name: Liu JiajingEmail: 94520773@ Number: 86 18602718625 To view the source version of this press release, please visit Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Globe and Mail
19-06-2025
- Business
- Globe and Mail
The Economics and Management School of Wuhan University Has Been Re-Accredited by EQUIS for the Highest Five-Year Period
Wuhan, China--(Newsfile Corp. - June 19, 2025) - Recently, the European Foundation for Management Development (EFMD) released a formal letter informing that the Economics and Management School (EMS) of Wuhan University (WHU) has successfully gained the five-year re-accreditation of EQUIS (EFMD Quality Improvement System). This is the first time that the EMS has been accredited by EQUIS' highest honor, a five-year period, following its first accreditation in 2016. This figure displays the EQUIS Five-Year Accreditation Certificate first awarded to the School of Economics and Management, Wuhan University. To view an enhanced version of this graphic, please visit: In March this year, an EQUIS peer review team, led by Professor Peter Møllgaard (President, Copenhagen Business School, Denmark), conducted a three-day comprehensive on-site evaluation at WHU. The panel included Professor Caitlin Byrne (Pro Vice Chancellor, Griffith University, Australia), Professor Wei Gu (Dean, School of Economics and Management, University of Science and Technology Beijing), and Mr. Jacques Delplancq (Former Deputy General Manager, IBM France). The practice of EMS was thoroughly inspected through in-depth exchanges with Huang Taiyan (Secretary, Party Committee, WHU), Zhu Deyou (Vice President, WHU), Yuan Yufeng (Vice President, WHU), heads of relevant departments, and representatives of faculty members, students, alumni, corporate partners, etc. Cannot view this video? Visit: EQUIS accreditation is known for its rigorous evaluation process and excellent quality requirements. Since initiating its international accreditation journey in 2010, EMS has successively earned three top-notch accreditations: AMBA, EQUIS, and AACSB. Hashtag: #TheEconomicsandManagementSchoolofWuhanUniversity The issuer is solely responsible for the content of this announcement. To view the source version of this press release, please visit
Malay Mail
19-06-2025
- Business
- Malay Mail
The Economics and Management School of Wuhan University has been Re-accredited by EQUIS for the Highest Five-year Period
Caption: This figure displays the EQUIS Five-Year Accreditation Certificate first awarded to the School of Economics and Management, Wuhan University. WUHAN, CHINA - Media OutReach Newswire - 19 June 2025 - Recently, the European Foundation for Management Development (EFMD) released a formal letter informing that the Economics and Management School (EMS) of Wuhan University (WHU) has successfully gained the five-year re-accreditation of EQUIS (EFMD Quality Improvement System). This is the first time that the EMS has been accredited by EQUIS' highest honor, a five-year period, following its first accreditation in March this year, an EQUIS peer review team, led by Professor Peter Møllgaard (President, Copenhagen Business School, Denmark), conducted a three-day comprehensive on-site evaluation at WHU. The panel included Professor Caitlin Byrne (Pro Vice Chancellor, Griffith University, Australia), Professor Wei Gu (Dean, School of Economics and Management, University of Science and Technology Beijing), and Mr. Jacques Delplancq (Former Deputy General Manager, IBM France). The practice of EMS was thoroughly inspected through in-depth exchanges with Huang Taiyan (Secretary, Party Committee, WHU), Zhu Deyou (Vice President, WHU), Yuan Yufeng (Vice President, WHU), heads of relevant departments, and representatives of faculty members, students, alumni, corporate partners, accreditation is known for its rigorous evaluation process and excellent quality requirements. Since initiating its international accreditation journey in 2010, EMS has successively earned three top-notch accreditations: AMBA, EQUIS, and #TheEconomicsandManagementSchoolofWuhanUniversity The issuer is solely responsible for the content of this announcement.
