Latest news with #YangLiu
Yahoo
7 days ago
- Business
- Yahoo
OncoC4 to Present at the 2025 Orphan Drug Summit on Strategies to Eliminate Anti-Drug Antibodies in Orphan Therapies
Multipronged approach to overcome the challenge of anti-drug antibodies to serve as the foundation of new subsidiary, AdaMunix ROCKVILLE, Md., July 15, 2025 (GLOBE NEWSWIRE) -- OncoC4, Inc., a late-stage biopharmaceutical company developing novel medicines for cancer, today announced it will present at the upcoming 2025 Orphan Drug Summit being held July 16-27, 2025, in Boston, Massachusetts. The presentation will include information on novel platforms developed to address the challenges of anti-drug antibodies (ADAs), which will serve as the basis for OncoC4's new subsidiary, AdaMunix. 'ADAs are a pervasive barrier to protein-based therapeutics, diminishing drug efficacy and contributing to significant adverse events,' said Yang Liu, PhD, Co-Founder, Chief Executive Officer (CEO), and Chief Scientific Officer (CSO) of OncoC4. 'To overcome these challenges, we've established multiple platforms designed to eliminate ADAs and enhance the efficacy and safety of antibody, enzyme, and gene therapies. Through AdaMunix, we aim to harness the potential of these technologies to make a dramatic impact on the lives of patients across a wide range of indications.' AdaMunix's ADA-X technology is designed to create drug-specific agents that neutralize ADAs when combined with approved therapeutics, and in vivo studies have demonstrated near-complete elimination of ADAs for several approved drugs. Its complementary BCR-X technology enables the development of next-generation ADA-stealth protein therapeutics inherently resistant to ADA activity. Based on promising preclinical results, AdaMunix has advanced three programs to pre-IND development. For more information, visit Presentation Details Title: Platform to Eliminate Anti-Drug Antibodies in Orphan Therapies Date: Thursday, July 17, 2025 Time: 11:00 – 11:25 AM ET Presenter: Yang Liu, PhD, Co-Founder, CEO and CSO About OncoC4 Based in Rockville, Maryland, OncoC4 is a privately held, late-stage biopharmaceutical company that is actively engaged in the discovery and development of novel biologicals for the treatment of cancer and immunological diseases. OncoC4's pipeline features assets with first-in-class and best-in-class potential targeting both novel and well validated targets across oncology and immunological diseases. Among them, AI-081 is a fully owned and potentially best-in-class bispecific antibody candidate targeting PD-1 and VEGF. AI-081 is currently enrolling patients in a Phase1/2 trial that could enable two or more pivotal studies. In addition, OncoC4 has a strategic collaboration with BioNTech to co-develop gotistobart (BNT316/ONC-392), a next-generation anti-CTLA-4 antibody candidate, in multiple solid tumor indications, including an ongoing pivotal clinical trial in squamous non-small cell lung cancer. More information: CONTACTS OncoC4Investor Contact:Bill BegienOncoC4, FoliasLifeSci Advisorsafolias@ Media Contact: Jason Braco, Communicationsjbraco@ in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
India Today
04-06-2025
- Climate
- India Today
Canadian wildfire smoke spreads across a third of US, worsens air quality
Smoke from wildfires burning in Canada spread across nearly one-third of the United States on Wednesday, according to forecasters. Most areas didn't face serious air quality issues, but some parts of New England, New York state, and the Midwest faced unhealthy haze, which brought hazardous levels of particulate pollution to Minnesota a day earlier, stretched from the Dakotas through the Ohio Valley, into the Northeast and as far south as Georgia, according to the National Weather Service's Weather Prediction Centre in College Park, Maryland. It was especially thick in New York and New of the smoke is aloft in the upper atmosphere, so in a lot of areas there aren't air quality issues," said Marc Chenard of the National Weather Service. "But there are air quality issues as far south as New York and Connecticut, where it's thicker and in the lower atmosphere."CANADA BATTLES MASSIVE FIRES The smoke originated from hundreds of wildfires burning in Canada since early May. As of Tuesday, more than 212 fires were active across the country, with half of them out of control, said the Canadian Interagency Forest Fire Centre. The worst fires are in the provinces of Manitoba, Saskatchewan, and Alberta. So far, 2 million hectares (or 4.9 million acres) have warned that smoke can be harmful to health. Yang Liu, an environmental health professor at Emory University in Atlanta, said, "It will affect everyone at some level, all walks of life. It's bad." He explained that the smoke contains tiny toxic particles -- smaller than 1/40th of a human hair -- that can enter the lungs and even reach the quality is worst in Williamstown, Massachusetts, near the borders of Vermont and New York. The town recorded a "very unhealthy" score of 228, according to IQAir, which tracks global air quality. A score below 50 is considered good, while anything above 100 is considered quality levels in some parts of the Midwest had also improved on Wednesday morning. Ely, near Minnesota's border with Manitoba, registered a "moderate" reading of 65, down from 336 on Tuesday. Minneapolis, which was ranked as the third-worst city in the world for air quality on Tuesday, with a 168 reading, registered at inputs from Reuters
GMA Network
04-06-2025
- Climate
- GMA Network
Canadian wildfire smoke spreads across a third of US
Smoke from wildfires burning in three Canadian provinces covered about a third of the US on Wednesday, forecasters said, but had little effect on air quality except in New England and parts of New York state and the Midwest. The haze, which brought hazardous levels of particulate pollution to Minnesota a day earlier, stretched from the Dakotas through the Ohio Valley, into the Northeast and as far south as Georgia, according to the National Weather Service's Weather Prediction Center in College Park, Maryland. It was especially thick in New York and New England. "Much of the smoke is aloft in the upper atmosphere, so in a lot of areas there aren't air quality issues," said the National Weather Service's Marc Chenard. "But there are air quality issues as far south as New York and Connecticut where it's thicker and in the lower atmosphere." Scores of wildfires have spread across Canada since the start of May. More than 212 active fires were burning in the country as of Tuesday afternoon, half of which were out of control, according to the Canadian Interagency Forest Fire Center. So far, 2 million hectares (4.9 million acres) have burned. Most of the fires were in the west-central provinces of Manitoba, Saskatchewan and Alberta. Yang Liu, a professor of environmental health at Emory University in Atlanta, said infants, the elderly and other frail people were most susceptible to the smoke, but emphasized that everyone is at risk. "It will affect everyone at some level, all walks of life," Liu said. "It's bad." He said the smoke is comprised of small particles, some of them toxic, that are smaller than 1/40th of the width of a human hair and can get into the lungs and even dissolve into the bloodstream. One of the worst spots for air quality in the US Northeast on Wednesday morning was Williamstown, Massachusetts, near the state's borders with Vermont and New York. It registered a "very unhealthy" reading of 228, according to IQAir, a website that monitors air quality around the world. An air quality rating of below 50 is considered to be "good," and readings between 100 and 300 are deemed "unhealthy" to "very unhealthy," while higher than that is considered "hazardous," according to the website. The ratings in other parts of the US Northeast were much lower, with New York City's standing at 56 on Wednesday morning and Washington's registering at 55. Air quality levels in some parts of the Midwest had also improved on Wednesday morning. Ely, near Minnesota's border with Manitoba, registered a "moderate" reading of 65, down from 336 on Tuesday. Minneapolis, which had ranked as third-worst city in the world for air quality on Tuesday, with a 168 reading, was registering at 96. — Reuters
Reuters
04-06-2025
- Climate
- Reuters
Canadian wildfire smoke spreads across a third of US
June 4 (Reuters) - Smoke from wildfires burning in three Canadian provinces covered about a third of the U.S. on Wednesday, forecasters said, but had little effect on air quality except in New England and parts of New York state and the Midwest. The haze, which brought hazardous levels of particulate pollution to Minnesota a day earlier, stretched from the Dakotas through the Ohio Valley, into the Northeast and as far south as Georgia, according to the National Weather Service's Weather Prediction Center in College Park, Maryland. It was especially thick in New York and New England. "Much of the smoke is aloft in the upper atmosphere, so in a lot of areas there aren't air quality issues," said the National Weather Service's Marc Chenard. "But there are air quality issues as far south as New York and Connecticut where it's thicker and in the lower atmosphere." Scores of wildfires have spread across Canada since the start of May. More than 212 active fires were burning in the country as of Tuesday afternoon, half of which were out of control, according to the Canadian Interagency Forest Fire Centre. So far, 2 million hectares (4.9 million acres) have burned. Most of the fires were in the west-central provinces of Manitoba, Saskatchewan and Alberta. Yang Liu, a professor of environmental health at Emory University in Atlanta, said infants, the elderly and other frail people were most susceptible to the smoke, but emphasized that everyone is at risk. "It will affect everyone at some level, all walks of life," Liu said. "It's bad." He said the smoke is comprised of small particles, some of them toxic, that are smaller than 1/40th of the width of a human hair and can get into the lungs and even dissolve into the bloodstream. One of the worst spots for air quality in the U.S. Northeast on Wednesday morning was Williamstown, Massachusetts, near the state's borders with Vermont and New York. It registered a "very unhealthy" reading of 228, according to IQAir, a website that monitors air quality around the world. An air quality rating of below 50 is considered to be "good," and readings between 100 and 300 are deemed "unhealthy" to "very unhealthy," while higher than that is considered "hazardous," according to the website. The ratings in other parts of the U.S. Northeast were much lower, with New York City's standing at 56 on Wednesday morning and Washington's registering at 55. Air quality levels in some parts of the Midwest had also improved on Wednesday morning. Ely, near Minnesota's border with Manitoba, registered a "moderate" reading of 65, down from 336 on Tuesday. Minneapolis, which had ranked as third-worst city in the world for air quality on Tuesday, with a 168 reading, was registering at 96.
Malay Mail
22-04-2025
- Business
- Malay Mail
Lee Kum Kee gives support to the 8th International Master Chef Charity Gala Dinner
Event brought together 2,300 chefs and guests to raise funds for the needy and promote Chinese culinary culture exchanges Over 1,000 master chefs from around the world gathered at the Xueye Lake International Conference Centre in Jinan. Master chefs from around the world at the Lee Kum Kee booth. JINAN, CHINA - Media OutReach Newswire - 22 April 2025 - From 14 to 16 April 2025, the 8International Master Chef Charity Gala Dinner was held at the Xueye Lake International Conference Centre in Laiwu, Jinan, marking the first-ever hosting of the event in mainland over 2,300 distinguished chefs attending from around the world – including overseas Chinese chefs, master chefs, celebrities and Michelin-starred chefs – the dinner not only set a new participation record, but raised over RMB10 million to be donated to the Jinan Charity Federation and Shanghai Charity Foundation to support public welfare its inception in 2014, the International Master Chef Charity Gala Dinner has been held in locations such as Taipei, Melbourne, Kuala Lumpur, Macau, Ho Chi Minh City, Singapore and Hong Kong. As well as showcasing mainland China's thriving foodservice industry, the 8edition in Jinan promoted Chinese culinary skills globally by facilitating international cultural exchanges and culinary innovation. A longtime supporter of this event, this year Lee Kum Kee acted as a strategic partner, demonstrating its leading status in the global food gala dinner was a resounding success, with Yang Li, Vice Mayor of Jinan; Ip Sio Man, President of the International Master Chef Charity Association; Yang Liu, President of the China Cuisine Association; Dodie Hung, Executive Vice President – Corporate Affairs of Lee Kum Kee Sauce; and Ross Tang, General Manager – Marketing of Lee Kum Kee Sauce in China being among the notable figures attending. Yang Liu remarked, "This is not only a gathering of the world's master chefs but also an international event celebrating 'Chinese Flavours and Love' – a magnificent demonstration of global chefs embracing social responsibility." During the event, Dodie Hung received an "Outstanding Contribution" award on behalf of Lee Kum three-day event featured four key activities: the 8International Master Chef Charity Gala Dinner, a Global Flavours Tasting Dinner, a Chinese Food Exhibition, and the International Chef Influence Forum cum "10 Celebrity Chefs Showcase."The charity dinner was sponsored by Lee Kum Kee, with chefs from around the world using the brand's products to showcase their culinary skills and creativity. Dishes such as "Shandong-style Braised Sea Cucumber with Scallions", "State Banquet Cuttlefish Roe Soup" and "Premium Oyster Sauce Braised South African Dried Abalone" were served, highlighting the unique brilliance of Chinese the "10 Celebrity Chefs Showcase", master chefs gave live cooking demonstrations using Lee Kum Kee sauces. Master chef Lu Yongliang's opening speech, "Maintaining the artisan spirit, spreading love, and the taste of China," moved fellow chefs to continue their pursuits of culinary 300 sauces and condiments from Lee Kum Kee were featured at the Global Flavours Tasting Dinner, providing creative inspiration for chefs from 26 countries and regions. The event explored culinary connections across the globe, resulting in a singular gastronomic experience that transcended geographical and cultural Lee Kum Kee presented its "Extraordinary Taste of China" promotion at the Chinese Food Exhibition, which included the launch of a limited-edition customised Premium Oyster Tang remarked "Lee Kum Kee's core value, 'Si Li Ji Ren' [considering others' interests] aligns perfectly with the mission of the International Celebrity Chef Charity Gala Dinner. Through our high-quality products, we aim to support chefs and families worldwide with diverse dining options, promote Chinese culinary culture, and make 'Chinese Flavours' a staple on dining tables around the world."Hashtag: #LeeKumKee The issuer is solely responsible for the content of this announcement. About LEE KUM KEE Lee Kum Kee is the global gateway to Asian culinary culture, dedicated to promoting Chinese culinary culture worldwide. Since 1888, it has brought people together over joyful reunions, shared traditions, and memorable meals. Beloved by consumers and chefs alike, Lee Kum Kee's range of more than 300 sauces and condiments sparks creativity in kitchens everywhere, inspiring professional and home chefs to experiment, create, and delight. Headquartered in Hong Kong, China and serving over 100 countries and regions, Lee Kum Kee's rich heritage, unwavering commitment to quality, sustainable practices, and "Constant Entrepreneurship" combine to enable superior experiences through Asian cuisine for people worldwide. For more information, please visit About the 8th International Master Chefs Charity Gala Dinner The 8th International Master Chefs Charity Gala Dinner was jointly organised by the International Master Chefs Charity Association and the Shandong Catering Industry Association, with support from the Asian Culinary Culture Promotion Association and World Chef Association. The event received endorsements from both the China Cuisine Association and Jinan Municipal People's Government and marked Jinan's first hosting of a charity event by an overseas non-profit organisation in several years. During the event, master chefs visited charitable organisations in Jinan and donated the RMB 10 million raised during the gala dinner to the Jinan Charity Federation and Shanghai Charity Foundation. The opening forum brought together leading Chinese and overseas Chinese culinary masters, including master chefs of a variety of Chinese cuisines, as well as food industry experts and hospitality sector representatives, fostering a dynamic exchange.
