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National Post
3 days ago
- Health
- National Post
Galderma Unveils Final Nine-Month Data Showing Lasting Efficacy and Patient Satisfaction With Its Injectable Aesthetics Portfolio When Addressing Facial Aesthetic Changes After Medication-Driven Weight Loss
Article content Sorry, your browser doesn't support embedded videos. Article content Final data from a first-of-its-kind clinical trial confirm that the combination of Sculptra ® and Restylane ® Lyft™ or Contour™* delivers sustained improvement in facial aesthetic appearance for patients experiencing facial volume loss due to medication-driven weight loss 1 Following interim analysis at three months presented earlier this year, a six-month extension study was conducted to capture the durability of treatment effects after nine months 1 Galderma continues to lead the response to addressing the aesthetic concerns of patients experiencing medication-driven weight loss, leveraging its deep dermatological expertise and working closely with healthcare professionals to meet evolving patient needs Article content Article content ZUG, Switzerland — Galderma has revealed positive final data from a phase IV first-of-its-kind trial exploring the benefits of Restylane Lyft or Contour in combination with Sculptra to address the aesthetic concerns of patients experiencing facial volume loss associated with medication-driven weight loss. 1 These data reinforce that this treatment regimen can effectively improve facial aesthetic appearance with high patient satisfaction over nine months. 1 Rates of medication-driven weight loss have increased rapidly in recent years and can be associated with facial alterations of variable magnitude. 2-4 Patients may experience facial changes such as dry, dull or sagging skin, a gaunt or hollowed-out facial appearance, or other unwelcome alterations to facial structure and balance. 3,4 As the pure-play dermatology category leader, Galderma is spearheading efforts to identify and address the most predominant aesthetic concerns of patients along their weight loss journey. Article content 'At Galderma, we are leading the charge in redefining aesthetic care for patients impacted by medication-driven weight loss. Our commitment is clear: to empower individuals to reclaim their confidence through cutting-edge, data-driven innovation and strategic collaboration with the world's foremost experts, and these latest study results reinforce this mission.' Article content GALDERMA Article content In the phase IV clinical study conducted in the U.S., Galderma investigated the aesthetic outcomes and appearance, and patient satisfaction of Restylane Lyft or Contour in combination with Sculptra for cheek or jawline augmentation and correction of contour deficiencies in patients experiencing facial volume loss associated with medication-driven weight loss. 1 The trial used the SHAPE Up Holistic Individualized Treatment (HIT™) – an individualized treatment approach which enables injectors to leverage their expertise with Galderma's Sculptra and its Restylane portfolio to optimize aesthetic outcomes while prioritizing patient satisfaction. Article content Patients were treated with Sculptra and either Restylane Lyft or Contour for their first treatment, a second treatment of Sculptra with an optional touch-up of Restylane Lyft or Contour at Week 4, and an optional third treatment of Sculptra at Week 8. 1 Following interim analysis at three months presented earlier this year, a six-month extension study was conducted to capture the durability of treatment effects after nine months. In the extension study, follow-up visits took place at Weeks 32 and 44 for those who received the third Sculptra treatment and at Weeks 28 and 40 for those who did not, corresponding to nine months after their first Sculptra treatment. 1 Results at nine months demonstrated that the combination of Sculptra and Restylane Lyft or Contour effectively improved the aesthetic appearance of patients experiencing facial volume loss associated with medication-driven weight loss, further supporting the benefits of the SHAPE Up HIT: 1 The combined Sculptra and Restylane Lyft or Contour regimen demonstrated skin quality improvements, with Restylane improving skin hydration and Sculptra significantly improving skin radiance through to Month 9 1 Subject satisfaction – which was reported by the majority of patients as early as Week 4 – was maintained through to Month 9: 1 85.7% of patients said their face looked less gaunt/sunken 1 88.6% said they 'loved' how the treatment maintained their facial structure 1 88.6% of patients said they 'loved' the regenerative effects of Sculptra treatment 1 88.6% felt they looked better than before the injection regimen 1 91.4% said they would recommend the injection regimen to others after weight loss and to those with loose, sagging facial skin 1 Safety was in line with previous pivotal trial data for Sculptra, Restylane Lyft and Contour, with no treatment-related adverse events reports. 1 'The improvements we observed with Sculptra and Restylane at nine months are hugely encouraging and represent a meaningful step forward in addressing the most predominant aesthetic concerns of patients along their weight loss journey. It was exciting to see the glow we've clinically observed in the past with Sculptra now validated through innovative bioinstrumentation tools in this study. For physicians and patients who are navigating the visible effects of medication-driven weight loss, this study delivers real, evidence-based solutions that can make a tangible difference to how individuals look and feel.' Article content 'These results really reinforce the role of aesthetic treatments, like Sculptra and Restylane, in supporting patients through their weight loss transformations, showing they can deliver visible improvements in skin quality while also significantly enhancing patient satisfaction and emotional wellbeing. The findings empower clinicians with data-backed tools to holistically address the nuanced aesthetic needs that arise with medication-driven weight loss, marking a pivotal moment where science meets patient-centered care.' Article content MICHAEL SOMENEK, M.D. Article content WASHINGTON DC, UNITED STATES Article content Galderma is spearheading multiple additional initiatives to identify and address the most predominant aesthetic concerns of patients who have experienced medication-driven weight loss through data-driven, innovative approaches in close collaboration with leading healthcare practitioners, as outlined in the company's recent report. 5 Galderma has supported pioneering research in the field, including the first recently published international consensus-based guidelines that provide a practical framework for practitioners to address the aesthetic needs of medication-driven weight loss patients, as well as research into the impact of medication-driven weight loss on the skin and the importance of factoring in aesthetic treatment goals during the patient journey. 6 * Restylane Contour is known as Restylane ® Volyme™ in countries outside of the U.S. Article content About the study Article content This phase IV trial was a multi-center, open-label study to evaluate the synergistic effects of Restylane Lyft or Contour in combination with Sculptra for cheek augmentation and correction of contour deficiencies, in patients experiencing facial volume loss following treatment with one of four brands of glucagon-like peptide-1 (GLP-1) receptor agonists. Article content 1 Article content Conducted in the U.S., the trial took place across two sites, and used the SHAPE Up Holistic Individualized Treatment (HIT) as a treatment methodology, with patients treated with Sculptra and either Restylane Lyft or Contour for their first treatment, a second treatment of Sculptra with an optional touch-up of Restylane Lyft or Contour at Week 4, and an optional third treatment of Sculptra at Week 8. Article content 1 Article content About Galderma Article content Galderma (SIX: GALD) is the pure-play dermatology category leader, present in approximately 90 countries. We deliver an innovative, science-based portfolio of premium flagship brands and services that span the full spectrum of the fast-growing dermatology market through Injectable Aesthetics, Dermatological Skincare and Therapeutic Dermatology. Since our foundation in 1981, we have dedicated our focus and passion to the human body's largest organ – the skin – meeting individual consumer and patient needs with superior outcomes in partnership with healthcare professionals. Because we understand that the skin we are in shapes our lives, we are advancing dermatology for every skin story. For more information: Article content Galderma. Data on file. Somenek M and Lorenc P. A multi-center, open-label study to evaluate the synergistic effects of biostimulator and dermal fillers for cheek augmentation and correction of contour deficiencies: Nine-month topline results. Mansour MR, et al. The rise of 'Ozempic Face': Analyzing trends and treatment challenges associated with rapid facial weight loss induced by GLP-1 agonists. JPRAS. 2024;96:225-227. doi: 10.1016/ Tay JQ. Ozempic face: A new challenge for facial plastic surgeons. JPRAS. 2023;81:97-98. doi: 10.1016/ Humphrey CD and Lawrence AC. Implications of Ozempic and other GLP-1 receptor agonists for facial plastic surgeons. Facial Plast Surg. 2023;39:719-721. doi: 10.1055/a-2148-6321 Galderma. Balancing The Scales: Advancing Aesthetics In The Era Of Medication-driven Weight Loss Transformations. July 2025. Available online Nikolis A, et al. Consensus Statements on Managing Aesthetic Needs in Prescription Medication-Driven Weight Loss Patients: An International, Multidisciplinary Delphi Study. JCD. 2025;24: e70094. Article content Article content Article content Article content Article content Contacts Article content Christian Marcoux, Chief Communications Officer +41 76 315 26 50 Article content Richard Harbinson Corporate Communications Director +41 76 210 60 62 Article content Céline Buguet Franchises and R&D Communications Director +41 76 249 90 87 Article content Emil Ivanov Head of Strategy, Investor Relations, and ESG +41 21 642 78 12 Article content Article content Article content
National Post
10-07-2025
- Business
- National Post
Sun Valley Investments A.G. Files Lawsuit Against Former Consultant, Onil Gunawardana and his Company, Akalytic Advisors, LLC for Misappropriation of Trade Secrets
Article content ZUG, Switzerland — Sun Valley Investments AG (' Sun Valley ') a leading private international investment firm, announced today that it filed a lawsuit in the United States District Court for the Northern District of California on July 9, 2025, against former consultant Onil Gunawardana and his company, Akalytic Advisors, LLC for misappropriation of trade secrets, and other claims. Article content According to the lawsuit, Mr. Gunawardana, during his tenure as a consultant for Sun Valley Investments A.G., stole valuable trade secret source code from Sun Valley. Sun Valley alleges that Mr. Gunawardana and Akalytic Advisors, LLC, are unlawfully using that source code for their own benefit, without Sun Valley's permission, and in violation of Mr. Gunawardana's legal obligations as a former consultant. Article content Article content Sun Valley Investments A.G. takes the protection of its intellectual property and confidential business information very seriously and is committed to safeguarding its valuable proprietary data. Article content The lawsuit seeks injunctive relief and damages for the alleged misappropriation and unauthorized use of Sun Valley's trade secrets. Sun Valley Investments A.G. will not be providing further comment at this time due to the ongoing legal proceedings. Article content About Sun Valley Article content Sun Valley is a private investment firm focused on the metals and mining industry with portfolio companies and branch offices in the Americas, Europe and Asia. Sun Valley's senior leadership team has several decades of experience in mining and investment companies and combines investment skills across diverse asset classes with hands-on experience at both senior and junior companies in the precious metals mining and refining industry. The firm finances the entire precious metals supply chain: mineral exploration, mine construction, production, processing and refining. Article content Article content Article content Article content Article content
Associated Press
03-07-2025
- Business
- Associated Press
ICN Launches $ICNT, latest investment signals $470 million valuation
ZUG, Switzerland, July 3, 2025 /PRNewswire/ -- Impossible Cloud Network launches token on Bybit, Binance, Kraken, and other major exchanges following $34 million ecosystem raise Impossible Cloud Network (ICN) – a decentralized cloud services provider– is today announcing the launch of its $ICNT token through Tier 1 centralized exchanges Bybit, Binance, Kraken, Bitget, and more. The token launch follows a recently announced investment (valuation: $470 million) from NGP Capital, a deep tech fund that backed Xiaomi and Helium. ICN is the first decentralized cloud provider to match and surpass centralized hyperscalers in latency, availability, and performance. Its service is live and operating a fully open, multi-service, permissionless, and composable cloud infrastructure that integrates storage, compute, and networking at scale. The token listing comes just weeks after ICN attracted a substantial valuation of $470 million from Nokia-backed investor NGP Capital, which joined 1kx, No Limit Holdings, Protocol VC, HV Capital, and more in investing a total of $34 million into ICN. The Switzerland-based cloud network has substantial traction inside its ecosystem, handling over 23,000 cloud requests per second from its 1,000+ enterprise customers. This makes ICN one of the biggest revenue-generating decentralized physical infrastructure networks (DePINs) in the industry and places it in pole position to win the AI infrastructure race. ICN's CEO and co-founder is Kai Wawrzinek, a seasoned, billion-dollar company founder who successfully led his project, Goodgame Studios, to NASDAQ unicorn status in 2017. Commenting on the launch of $ICNT, Wawrzinek says: 'As a decentralized cloud provider, ICN is successful because it meets a genuine, growing need. ICN will win the decentralized infrastructure race — because we control the data layer. Once compute goes live, we'll unbundle the internet."$ICNT will play a pivotal role in ICN's ecosystem, allowing anyone to participate in the network's growth by earning rewards from HyperNodes. $ICNT is used both for provisioning hardware capacity and for staking to secure cloud workloads. This ties the token to real-world infrastructure and the strong and growing demand that ICN's ecosystem is experiencing. ICN is riding a confluence of multiple strong tailwinds in the cloud industry. These include incredible demand for AI, associated hardware shortages, and an increasingly urgent need for sovereign cloud solutions apart from those offered by US hyperscalers. Combined, these drivers are calling for a new foundational layer for the next generation of the internet that can challenge the dominance of centralized tech giants – a layer ICN is pioneering. About Impossible Cloud Network (ICN) Impossible Cloud Network (ICN) is building a permissionless, open cloud network to rival Big Tech giants like Amazon Web Services (AWS) and Google. With resilient, high-performance decentralized cloud services, ICN is laying the foundation for a scalable, secure, and community-driven global cloud that supports enterprise, AI, gaming, applications, and end-users. With real-world adoption already generating million-dollar revenue and a vision for 200+ decentralized cloud services, ICN offers a true alternative to monopolistic hyperscalers. About ICN: Full information on $ICNT : $ICNT on Bybit: Contact Rebecca Jones Block3 PR [email protected] Photo - View original content to download multimedia: SOURCE Impossible Cloud Network
Yahoo
02-07-2025
- Business
- Yahoo
Redslim Strengthens Its Technology Backbone With Partnership With Databricks
ZUG, Switzerland, July 02, 2025--(BUSINESS WIRE)--Redslim, a leading data management company specializing in optimizing syndicated market data, today announced its partnership with Databricks, the Data and AI company. This collaboration allows Redslim to reinforce its solutions with proven technology, establishing a resilient and future-ready foundation across its services. Across industries, with data sources becoming more fragmented and volumes rapidly surging across channels, many businesses are struggling to gain a unified view on market performance while balancing speed of implementation, quality, and ROI. This partnership comes at a time when scalable and reliable solutions are more critical than ever. Redslim specializes in transforming fragmented market measurement data into harmonized, ready-to-use data and BI assets. By integrating siloed data sources into centralized analytics systems, Redslim enables businesses to obtain actionable insights to make informed decisions as they boost revenue growth, improve marketing intelligence and drive operation excellence. Databricks Data Intelligence Platform democratizes access to analytics and intelligent applications by marrying customers' data with powerful AI models tuned to their business's unique characteristics. The platform is built on a lakehouse foundation of open data formats and open governance to ensure that all data is completely within the customers' control. Through this partnership, Redslim gains early access to the emerging capabilities from Databricks. This allows the team to stay ahead of the curve and strengthen its technical know-how. A key strength of Databricks lies in its agnostic data lake management and advanced AI capabilities, which align seamlessly with Redslim's expertise in managing diverse data sources through an agnostic approach. By integrating the latest innovations into its technology stack, Redslim ensures its clients benefit from high-standard solutions backed by the latest advancements in data technology. Coupled with Redslim's extensive industry expertise, the partnership allows Redslim to address client needs more effectively and help them achieve a stronger return on investment. "As data plays a critical role in helping our clients shape and execute their strategies, it's important that our services are supported by robust and AI-backed data infrastructure," said Alberto Alcaniz, Co-CEO at Redslim. "This partnership strengthens our technology capabilities as we continue advancing our solutions and broadening collaboration with clients' global IT teams, making sure seamless integration and long-term value for our clients." About Redslim Redslim streamlines data management for teams faced with the request to leverage fragmented datasets for critical decision making. Specialized in data engineering, harmonization and BI, their teams manage data from over 50 agencies and covering more than 55 countries. Their technology-enabled services optimize data consumption for more than 30 global organizations. Active for more than 10 years, Redslim is constantly innovating their solutions to always meet the evolving needs of their clients and data partners. Learn more at and follow Redslim on LinkedIn. View source version on Contacts 00447970019724 Sign in to access your portfolio
Associated Press
02-07-2025
- Business
- Associated Press
Redslim Strengthens Its Technology Backbone With Partnership With Databricks
ZUG, Switzerland--(BUSINESS WIRE)--Jul 2, 2025-- Redslim, a leading data management company specializing in optimizing syndicated market data, today announced its partnership with Databricks, the Data and AI company. This collaboration allows Redslim to reinforce its solutions with proven technology, establishing a resilient and future-ready foundation across its services. This press release features multimedia. View the full release here: Across industries, with data sources becoming more fragmented and volumes rapidly surging across channels, many businesses are struggling to gain a unified view on market performance while balancing speed of implementation, quality, and ROI. This partnership comes at a time when scalable and reliable solutions are more critical than ever. Redslim specializes in transforming fragmented market measurement data into harmonized, ready-to-use data and BI assets. By integrating siloed data sources into centralized analytics systems, Redslim enables businesses to obtain actionable insights to make informed decisions as they boost revenue growth, improve marketing intelligence and drive operation excellence. Databricks Data Intelligence Platform democratizes access to analytics and intelligent applications by marrying customers' data with powerful AI models tuned to their business's unique characteristics. The platform is built on a lakehouse foundation of open data formats and open governance to ensure that all data is completely within the customers' control. Through this partnership, Redslim gains early access to the emerging capabilities from Databricks. This allows the team to stay ahead of the curve and strengthen its technical know-how. A key strength of Databricks lies in its agnostic data lake management and advanced AI capabilities, which align seamlessly with Redslim's expertise in managing diverse data sources through an agnostic approach. By integrating the latest innovations into its technology stack, Redslim ensures its clients benefit from high-standard solutions backed by the latest advancements in data technology. Coupled with Redslim's extensive industry expertise, the partnership allows Redslim to address client needs more effectively and help them achieve a stronger return on investment. 'As data plays a critical role in helping our clients shape and execute their strategies, it's important that our services are supported by robust and AI-backed data infrastructure,' said Alberto Alcaniz, Co-CEO at Redslim. 'This partnership strengthens our technology capabilities as we continue advancing our solutions and broadening collaboration with clients' global IT teams, making sure seamless integration and long-term value for our clients.' About Redslim Redslim streamlines data management for teams faced with the request to leverage fragmented datasets for critical decision making. Specialized in data engineering, harmonization and BI, their teams manage data from over 50 agencies and covering more than 55 countries. Their technology-enabled services optimize data consumption for more than 30 global organizations. Active for more than 10 years, Redslim is constantly innovating their solutions to always meet the evolving needs of their clients and data partners. Learn more at and follow Redslim on LinkedIn. View source version on CONTACT: [email protected] 00447970019724 KEYWORD: EUROPE SWITZERLAND UNITED KINGDOM INDUSTRY KEYWORD: SOFTWARE TECHNOLOGY ARTIFICIAL INTELLIGENCE DATA MANAGEMENT SOURCE: Redslim Copyright Business Wire 2025. PUB: 07/02/2025 04:49 AM/DISC: 07/02/2025 04:49 AM
