Latest news with #antiaging
ABC News
16 hours ago
- Health
- ABC News
Can 'biological clock' tests tell you anything worthwhile?
We all like to imagine we're ageing well. Now a simple blood or saliva test promises to tell us by measuring our "biological age". And then, as many have done, we can share how "young" we really are on social media, along with our secrets to success. While chronological age is how long you have been alive, measures of biological age aim to indicate how old your body actually is, purporting to measure "wear and tear" at a molecular level. The appeal of these tests is undeniable. Health-conscious consumers may see their results as reinforcing their anti-ageing efforts, or a way to show their journey to better health is paying off. But how good are these tests? Do they actually offer useful insights? Or are they just clever marketing dressed up to look like science? Over time, the chemical processes that allow our body to function, known as our "metabolic activity", lead to damage and a decline in the activity of our cells, tissues and organs. Biological age tests aim to capture some of these changes, offering a snapshot of how well, or how poorly, we are ageing on a cellular level. Our DNA is also affected by the ageing process. In particular, chemical tags (methyl groups) attach to our DNA and affect gene expression. These changes occur in predictable ways with age and environmental exposures, in a process called methylation. Research studies have used "epigenetic clocks", which measure the methylation of our genes, to estimate biological age. By analysing methylation levels at specific sites in the genome from participant samples, researchers apply predictive models to estimate the cumulative wear and tear on the body. Although the science is rapidly evolving, the evidence underpinning the use of epigenetic clocks to measure biological ageing in research studies is strong. Studies have shown epigenetic biological age estimation is a better predictor of the risk of death and ageing-related diseases than chronological age. Epigenetic clocks also have been found to correlate strongly with lifestyle and environmental exposures, such as smoking status and diet quality. In addition, they have been found to be able to predict the risk of conditions such as cardiovascular disease, which can lead to heart attacks and strokes. Taken together, a growing body of research indicates that at a population level, epigenetic clocks are robust measures of biological ageing and are strongly linked to the risk of disease and death. While these tests are valuable when studying populations in research settings, using epigenetic clocks to measure the biological age of individuals is a different matter and requires scrutiny. For testing at an individual level, perhaps the most important consideration is the "signal to noise ratio" (or precision) of these tests. This is the question of whether a single sample from an individual may yield widely differing results. A study from 2022 found samples deviated by up to nine years. So an identical sample from a 40-year-old may indicate a biological age of as low as 35 years (a cause for celebration) or as high as 44 years (a cause of anxiety). While there have been significant improvements in these tests over the years, there is considerable variability in the precision of these tests between commercial providers. So depending on who you send your sample to, your estimated biological age may vary considerably. Another limitation is there is currently no standardisation of methods for this testing. Commercial providers perform these tests in different ways and have different algorithms for estimating biological age from the data. As you would expect for commercial operators, providers don't disclose their methods. So it's difficult to compare companies and determine who provides the most accurate results — and what you're getting for your money. A third limitation is that while epigenetic clocks correlate well with ageing, they are simply a "proxy" and are not a diagnostic tool. In other words, they may provide a general indication of ageing at a cellular level. But they don't offer any specific insights about what the issue may be if someone is found to be "ageing faster" than they would like, or what they're doing right if they are "ageing well". So regardless of the result of your test, all you're likely to get from the commercial provider of an epigenetic test is generic advice about what the science says is healthy behaviour. While companies offering these tests may have good intentions, remember their ultimate goal is to sell you these tests and make a profit. And at a cost of around $500, they're not cheap. While the idea of using these tests as a personalised health tool has potential, it is clear that we are not there yet. For this to become a reality, tests will need to become more reproducible, standardised across providers, and validated through long-term studies that link changes in biological age to specific behaviours. So while one-off tests of biological age make for impressive social media posts, for most people they represent a significant cost and offer limited real value. The good news is we already know what we need to do to increase our chances of living longer and healthier lives. These include: We don't need to know our biological age in order to implement changes in our lives right now to improve our health. Hassan Vally is an associate professor of epidemiology at Deakin University. This piece first appeared on The Conversation.
The Sun
2 days ago
- Health
- The Sun
Celeb doctor injected Botox up my NOSE – people tell me I look great thanks to little known secret treatment
LET me start by saying I'm not anti-ageing or anti-wrinkle - at 27, I've got no problem with the idea of looking more mature, and I've come to like the little lines that appear when I laugh and smile. Maybe that will all change. 12 12 But after months of looking at my face in Zoom meetings and feeling like I appeared a little more tired and weathered than I felt, I started to get curious about Botox. Not the frozen, wind-tunnel kind, I wanted the whisper of change… the kind that celebrities have before stepping out to say they've tried a new product that's entirely changed their face shape. The kind of tweak where your friends ask if you've 'been sleeping better lately' or started 'using laser treatments' because you've been looking 'more glowy lately'. Enter: Baby Botox. Now, I'd heard all the buzz, and the warnings, about microdoses of Botox that are there not to freeze your face in one place, but just soften things slightly, touch things up like Photoshop. And after a few deep dives on TikTok and a couple of late-night WhatsApp group chats (cue my entire family threatening to disown me), I booked an appointment with Dr Brendan Khong. Dr Khong is not your average injector. First off, he doesn't believe in the whole ' preventative Botox ' craze that's everywhere online at the moment, even if I desperately wanted him to. This is not, he was clear, about injecting twenty-something's into oblivion to change their appearance, and it's not a rocket into the space of an entire new look, just a gentle nudge into the stratosphere. Think a refresh without diving headfirst into the ever-growing pool of fillers, from lips to cheeks to chin to nose, and it all made perfect sense to me. I went in asking for three things: a lip flip to lift my top lip slightly without using filler, jaw Botox to slim the face and ease my clenching habit, and a bit of brow Botox to give me that snatched, slightly lifted look, think high fashion catwalk model, not permanently surprised. Instead of plumping the lips with filler, Dr Khong popped a tiny amount of Botox just above my lip, to relax the muscle enough to encourage it to flip up, giving a poutier look without adding volume. I'm Olivia Attwood's beautician here's why you should avoid 'preventative Botox' It doesn't make you look like you've had anything done, just like my top lip, which for a while felt like it was on strike in smiley photos, decided to show up to the party for once. The jaw Botox was a little more… spicy - I was warned the needle might feel a little deeper in the skin. I've had tattoos in places that I've been warned will hurt and still managed to nap through it, but there's something about being pricked in your jaw muscles that makes you want to clench even harder. Not ideal. The magic is, if you can get through it, in the weeks that follow it slims your face by relaxing the masseter muscles, seeing them get smaller and smaller until they felt almost like they'd disappeared. My jaw hasn't felt this relaxed in years, though, eating anything chewy became a chore and I soon realised I'd have to cut my food up into tiny bits to handle the tiredness I'd feel from trying to work muscles that had been, essentially, put to sleep. Diet hack, I guess. The brow Botox was the cherry on top - a secret move Dr Khong told me was his 'signature'. Should I be worried? No. He showed me the results on other clients, and I was sold. 12 12 12 It's not a full-on brow lift, but the difference is real, as a friend told me just days after, I looked 'like I'd had a holiday, or a facial, or both at the same time.' I'll take it. And to top things off, Dr Khong surprised me by sticking the needle up my nose. Yes, you read that right - in the name facial balancing, one prick more didn't seem a bad idea. What surprised me most was how little Botox was actually used. Baby Botox really is a minimalist's dream. Dr Khong was conservative with the amount. He'd rather I come back for a top-up than overdo it. So what's it like immediately afterwards? Honestly, sort of anticlimactic. You're left with a few tiny needle marks which fade fast, and you can't lie down for four hours, no hardcore workouts, no drinking alcohol for at least 24 hours, no sun tanning, and no sex. Luckily, I went on a Wednesday. No plans in store. The results don't show up right away. It took about a week before I noticed the difference, but when I did? Everyone kept telling me how good my skin looked - and I got ID'd buying a pair of scissors. Not one person guessed Botox, so I could tell them green juice, and eight hours of sleep. Lies, all lies - and here I am, spoiling it all for myself. My face still moves, I can still frown (albeit mildly), and I haven't had to defend myself against a single 'you've had work done'. Instead, I just keep hearing: 'You look really well, what's your secret?' Just a few tiny jabs. But let's keep that between us, shall we? WILL BOTOX KNOCK YEARS OFF MY FACE? By Jack Hardwick "No gym, no sex and certainly no sunbeds for 24-48 hours" - words most guys would hate to hear. But as I sat in the plush clinic at 41 Harley Street, this was my reality. 12 12 Though I was promised the short term loss was worth it for the long term gain, as I was about to pop my Botox cherry. As for the reason for my self imposed gym and sex ban? Any strenuous exercise that would raise my heartrate runs the risk of causing the Botox to migrate before it settles into the muscles. The areas of concern? My very expressive 31-year-old forehead which seems to have a life of its own - especially after I have a drink - and my eyes. More and more over the past 12 months I've noticed my eyes were beginning to look tired. Dreaded crows feet were becoming more and more visible - especially in certain lighting like on the gym floor or in the office lifts. After months of deliberating with friends - both male and female - I have decided to take matters into my own hands. Many of my friends have been splashing out on Botox for years but for me it's always been a female option - somehow emasculating to admit I've given in to the age old quest of turning back the clock. But the past decade has seen a strong rise in men seeking out tweakments. The amount of money spent by men on Botox rose by 400 per cent between 2000 and 2023, according to the American Society of Plastic Surgeons. In 2020 alone, it's estimated that 265,000 men had Botox procedures. Even with that in mind, as I sat down to pop my Botox cherry with Dr Ross at Cosmedics on Harley Street, my brief was clear - I wanted subtle touch ups rather than looking like I was frozen in time. Enough to enhance my look, but subtle enough I could deny if anyone were to ask me. After being marked up with no less than 20 injection points, it was time to receive my Botox. The best way to describe the feeling is a wasp bite - a quick unpleasant crunch similar to being stung that's over as quick as it began. 'Exactly what I wanted' The worst of these came in the six - three each side - around my eyes. But even then, it was hardly painful. I was told it could take up to a week for the Botox to kick in but due to it being my first time I could feel my forehead freezing up within 48 hours. Some of my mates love the feeling, I on the other hand was unsure. Initially I admit I missed my formerly very expressive forehead but within a week I was super happy with my new smooth complexation. When it comes to the six injections I had to remove my crows feet, I couldn't be happier from the get go. Thanks to a few little pricks, this issue has gone. Has it knocked years off my face? No. But do I look fresher and more youthful? Yes. At least I think so - and to be honest that's more than enough for me. In fact, the few people I have told about my trip to Cosemedics had zero idea I'd had anything done - exactly what I wanted. Though after showing them before and after pictures everyone can see the improvement. Even my mum, who living in a rural village in Derbyshire couldn't be further away from the often shallowness of London, conceded she thought it looked good. Do's & Don'ts before and after Botox Dr. Aamer Khan reveals the do's and don'ts with Botox Do's Before Botox Consult a qualified practitioner with medical training and experience. Inform your practitioner about all medications, supplements, and medical conditions. Avoid alcohol and blood-thinning medications (aspirin, ibuprofen, vitamin E) for 24–48 hours. Stay hydrated and have a light meal before your appointment. Ask questions about the procedure, expectations, and outcomes. Don'ts Before Botox Avoid retinol, glycolic acid, or exfoliants on treatment areas for 24 hours. Don't schedule within 2 weeks of major events to allow time for the treatment to work and any healing. needed, possible bruising, which can occur. Reschedule if you're feeling unwell (cold, infection, etc.). Try to avoid makeup on the day of treatment, unless it is mineral make up. Do's After Botox Gently move treated muscles (smile, frown) to help Botox settle. Stay upright for 4–6 hours post-treatment. Apply cold compresses gently to reduce swelling if there is any. Use mild, non-active skincare to keep skin clean and calm. Don'ts After Botox Do not lie down or bend over for at least 4–6 hours. Avoid touching or rubbing the injected area for 24 hours. Skip workouts and heat exposure (gym, saunas, hot yoga) for 24 hours. Don't apply makeup or active skincare for at least 12–24 hours. Avoid alcohol and blood thinners for 24 hours post-treatment. For any concerns post-treatment, always contact your provider directly. Mild redness, swelling, or bruising is common and usually subsides within a few days.
Yahoo
2 days ago
- Health
- Yahoo
Why Spas Are Trading Cucumber Water for Longevity Treatments
Stefan Safko is the CEO of a robotics start-up in his early forties. He has a successful professional life, a fulfilling personal one, and, by any traditional metric, is in the top percentile of health. He has no chronic diseases, exercises frequently, and has been a lifelong healthy eater. But like most driven and accomplished people, he'd like to level up. While Safko isn't by any means looking to become the next Bryan Johnson, spending $2 million a year on anti-aging efforts, he is one of many in the tech and business spaces pursuing a longer, healthier life. 'I read books and seek out 'credible' individuals and materials online for guidance,' says Safko. 'There tends to be a lot of noise, especially with social media personalities becoming overnight authorities and fads that are more social media–driven versus science-backed.' Safko is clearly not interested in the traditionally 'woo woo' conception of 'wellness,' one that conjures up images of tambourine-shaking gurus more than evidence-based medical care. Fortunately for him, science-backed wellness has exploded in popularity in the last few years—and the ground zero for this development may be a bit surprising. Instead of a Beverly Hills or Silicon Valley doctor's office, these scientific treatments are currently found at spas. More from Robb Report What Happened When This Founder Bought His Winery Back From Its Corporate Parent Yacht Builders Are Investing in the Art World. Here's Why. Pomellato's New High Jewelry Collection Is an Ode to Its Most Defining Decades Heritage resorts like Pebble Beach now offer infrared light treatments and antigravity chairs alongside their traditional golf game–enhancing physical therapies. Established European names like Preidlhof and Sha Wellness offer medical-grade sleep clinics and electromagnetic pulse treatments. Velaa Private Island, an exclusive hotel in the famously tropical Maldives, has been heavily (and successfully) promoting its paradoxically arctic cryotherapeutic 'snow room.' Treatments like vitamin IVs, stem cell therapies, and myriad biometric tests aimed at creating individualized treatments are now par for the course at top resorts worldwide. Unlike traditional medi-spas, these programs position themselves as part of a more holistic approach to long-term wellbeing, one tailored not to treating existing complaints but to the broader pursuit of optimal living. So how exactly did the former domain of couples' massages and cucumber water become the next frontier in medicine? According to Dr. Shah, it's where people are already used to spending their own money on wellness. While it may seem tricky for spas to balance being part medical lab, part aromatherapeutic oasis, spa director Pat Makozak of the Four Seasons Maui at Wailea hasn't had any issues. 'It's all the same goal,' she says. 'When guests call to book a massage, if they know we have IV treatments available, they'll just add that on. We already offered some technology with the spa treatments: we have an infrared light in every massage room, and a cryotherapy machine that we incorporate into facials.' Makozak brings up a good point. We already have beauty-focused treatments like Botox and cryotherapy in the spa space—why not use them for our actual health? Medi-spas having long integrated science into elective treatments is meant purely to enhance quality of life, so perhaps it's not so surprising the future of holistic medical wellness has taken root in the same soil. While there's certainly nothing like chemo or surgery happening on any massage tables, doctors are primarily responsible for crafting these new spa menus. Some medical professionals see these endeavors as a step in the right direction for a much-needed expansion of our ideas of health and wellness; others see it as an unnecessary money grab. Monty Dunn, MD, a doctor of anesthesiology in San Francisco, is one of those skeptics. For example, Dr. Dunn points out that there is no evidence supporting the effectiveness of almost all vitamins and supplements, let alone the popular IV versions (which he characterizes as 'hydration therapy' at most). While stem cell therapy is trendy, Dr. Dunn is quick to remind that science has not yet discovered how to induce stem cells to differentiate into anything specific, meaning that injected stem cells likely do nothing at best, and could theoretically become cancer at worst. Yes, all the biometric and blood panel testing to identify disease propensities are nice, and will likely become increasingly popular in the private sector. However, Dr. Dunn explains that we don't actually know the markers for many common diseases, which renders the current screenings far from revolutionarily useful at this time. According to Vishal Patel, MD, PhD, and chief medical officer at Sensei (the Larry Ellison–founded wellness retreat that exclusively offers science-backed treatments), well-educated wellbeing seekers like Safko are these institutions' primary audience. 'The intersection of health, wellness, and travel has grown exponentially in recent years,' observes Patel. This is likely a result of our current healthcare system, which Darshan Shah, MD—the founder of health optimization and longevity center Next Health, who provides medical offerings at the Four Seasons Maui spa—describes as 'disease care.' American healthcare is traditionally focused on treating pathologies; in other words, it addresses issues only after they've grown to become major problems. This system has left a hole in the market for those looking for medical-grade care focused on prevention and optimization as opposed to triage. Dr. Dunn does agree that our healthcare system has overly emphasized quick problem solving, but believes it's the reason why the mortality-obsessed rich are quick to shell out for snake-oil placebos and hacks before making sustainable lifestyle changes. Jim Cahill, a mindset guide at Sensei and expert in contemplative neuroscience, has likewise identified the desire for quick fixes as a common mindset, but believes it can be worked with. 'There's nothing inherently wrong with seeking immediate results, and [Sensei's] wellness assessments can and do target immediate improvements in sleep, diet, stress management, and movement,' he says. 'But the evidence is just too clear: we can do much more by sustaining that wider perspective. Lifelong wellness requires that comprehensive approach, where temporary practices become sustained lifestyles.' Ronjon Nag, a famed tech inventor and entrepreneur who currently heads an AI and Longevity VC firm while teaching the same at Stanford, unequivocally believes in science's ability to hack lifespan and wellness. In conversation with Robb Report, he expanded on the many companies he's invested in with pursuits ranging from mitochondrial rejuvenation to epigenetic reprogramming to even a vaccine to slow aging. Though clearly more optimistic than Dr. Dunn about the future of medical wellness, he agrees it will be the private sector moving things forward by pushing more patient-driven, test-centric approaches. Given Nag's background with developing tech and AI we now use every day, his predictions (and investments) are likely ones to watch for those interested in the field. I asked Dr. Shah for his tips for those looking to get into such treatments, particularly when it comes to sorting out what is worth the cost and what may be simply expensive smoke and mirrors. Dr. Shah recommended only going to facilities where a licensed MD oversees the program, and consulting with your personal physician prior about the treatments you'd like to try. While many treatments may be technically safe and somewhat effective, a physician will be able to advise as to whether they are worth the often steep cost. It's also a good idea to ask yourself what you're looking to get out of the treatment: Are you looking for a quick fix, or are you ready to make the sustained lifestyle changes these programs often recommend? For now, if you're looking to become more proactive about your health and longevity, the spa is the best place to find that full-body workup or biomarker-informed longevity session. Just don't expect insurance to cover it. Best of Robb Report The Ultimate Miami Spa Guide: 15 Luxurious Places to Treat Yourself The 7 Most Insanely Luxurious Spas in the World, From Tokyo to Iceland 17 Reasons the Caribbean Should Be at the Top of Your Travel Itinerary Click here to read the full article.
The Independent
2 days ago
- Health
- The Independent
Study helps explain common vitamin's extraordinary power to reverse skin ageing
Vitamin C prevents age-related thinning of the skin by switching on genes that promote skin cell growth, a new study has found. The research, published in the Journal of Investigative Dermatology, could lead to new clinical treatment strategies using vitamin C to appear younger than one's actual age. ' Vitamin C is a promising molecule that can be used to develop treatment for epidermal thinning, including in aging,' the study says. The skin is the body's first line of defence against external threats, but its outermost layer, the epidermis, gradually grows thinner and loses its protective strength, contributing to ageing. This outer layer is made of cells called keratinocytes, which originate from deeper layers and migrate upward. Previous studies show that vitamin C plays a key role in rejuvenating skin with its antioxidant properties. Now, researchers say it helps prevent skin thinning by directly activating genes that control skin cell growth and development. "Vitamin C seems to influence the structure and function of epidermis, especially by controlling the growth of epidermal cells,' says study author Akihito Ishigami. 'We investigated whether it promotes cell proliferation and differentiation via epigenetic changes.' The study assessed lab-grown cells closely mimicking human skin. Exposed to air while being nourished from underneath by a liquid nutrient medium, the cells replicated the way human skin would receive nutrients from underlying blood vessels. When researchers applied vitamin C in concentrations comparable to those typically transported from the bloodstream into the epidermis, they found the skin showed a thicker epidermal cell layer on day seven. In only two weeks, the inner layer was even thicker, suggesting that vitamin C was promoting the formation and division of keratinocytes. The study also notes that the vitamin helps skin cells grow by switching on dormant genes associated with cell proliferation. When a DNA section is bound to molecules called methyl groups, it helps suppress a gene 's activity. Vitamin C promotes the removal of such methyl groups from DNA in these skin cells, thereby helping them grow, multiply, and differentiate. These findings finally reveal how vitamin C promotes skin renewal by triggering genetic pathways involved in growth and repair. This could be particularly helpful for older adults or those with damaged or thinning skin, researchers say. "We found that VC helps thicken the skin by encouraging keratinocyte proliferation through DNA demethylation, making it a promising treatment for thinning skin, especially in older adults," Dr Ishigami says.
Daily Mail
2 days ago
- Health
- Daily Mail
Users say this new wrinkle-smoothing retinol skincare transforms skin in just WEEKS: 'Smooth, supple and more youthful'
Beauty buffs looking to smooth fine lines and plump the skin fast are racing to shop the brand new High Potency Retinol skincare from Perricone MD, designed to deliver visible results in as little as one month. Featuring a face and eye serum supercharged with a triple retinol blend, this new collection has been clinically proven to reduce signs of ageing without sensitivity – and you can score a freebie worth £82 when you snap up both products today. Perricone MD Triple Retinol Renewal Eye Serum, 15ml £64 Perfect for making tired, lined eyes a thing of the past, the Triple Retinol Renewal Eye Serum works day and night to visibly reduce crow's feet, under-eye wrinkles and discolouration. Working hard without the sensitivity of other retinol formulas, this supercharged eye serum also helps to visibly brighten and minimise dark circles and darkness for a more open, awakened look, all the while leaving skin deeply hydrated. Shop Perricone MD Triple Retinol Renewal Face Serum £83 The Triple Retinol Renewal Face Serum is set to be the transformative solution your skin has been looking for. Similarly formulated with the brand's triple retinol blend, coenzyme Q10 and naturally derived betacarotene, this powerful day and night serum accelerates skin renewal with less sensitivity to deliver the look of collagen-rich, firmer skin. Shop Perfect for making tired, lined eyes a thing of the past, the Triple Retinol Renewal Eye Serum works day and night to visibly reduce crow's feet, under-eye wrinkles and discolouration That's right, when you shop the Perricone MD Triple Retinol Renewal Eye Serum and face serum, you'll receive a full-size Retinol Recovery Overnight Moisturizer 59ml (worth £82) for free, giving you all the tools you need for flawless skin. Creating luxury skincare products backed by powerful ingredients, cutting-edge research and extensive clinical and consumer studies, Perricone MD is the place to shop if you're looking for real results. Designed for those seeking visibly smoother, firmer and more refined skin, the new advanced Triple Retinol blend collection has been made with a proprietary formulation of three distinct forms of retinol, offering powerful results while minimising irritation. Unlike traditional formulas, Triple Retinol delivers gradual, controlled release to help target fine lines, uneven tone and texture – making it ideal for both new and experienced retinol users. And it's this Triple Retinol blend that powers the brand new eye and face serum, creating the perfect two-step routine for smoother, more youthful-looking skin. Perfect for making tired, lined eyes a thing of the past, the Triple Retinol Renewal Eye Serum works day and night to visibly reduce crow's feet, under-eye wrinkles and discolouration. Formulated with Perricone's proprietary triple retinol blend alongside antioxidant powerhouse coenzyme Q10 and naturally derived beta-carotene (vitamin A), this powerful eye serum accelerates skin renewal to reduce the look of under-eye puffiness and uneven texture for a firmer, smoother appearance. Working hard without the sensitivity of other retinol formulas, this supercharged eye serum also helps to visibly brighten and minimise dark circles and darkness for a more open, awakened look, all the while leaving skin deeply hydrated. In fact, in clinical trials on 34 women, 100 per cent showed significant improvement in skin hydration immediately after application, while after four weeks, 91 per cent showed a significant reduction in under-eye dark circles and 88 per cent showed a significant reduction in under-eye puffiness. And to compliment the supercharged eye serum? The Triple Retinol Renewal Face Serum is set to be the transformative solution your skin has been looking for. Similarly formulated with the brand's triple retinol blend, coenzyme Q10 and naturally derived betacarotene, this powerful day and night serum accelerates skin renewal with less sensitivity to deliver the look of collagen-rich, firmer skin. Showing significant results fast, the impressive serum helps to visibly diminish uneven texture, dullness and redness for a more even, radiant complexion, absorbing instantly for added hydration and glow. Clinical trials for the Triple Retinol Renewal Face Serum have been impressive, too, where when tested on 37 women, 76 per cent showed significant improvement in skin elasticity and resiliency in four weeks, and 78 per cent showed significant improvement in the feel of rough skin texture after eight weeks. Seventy-sixper cent showed a significant reduction in fine lines on the cheek and a significant reduction in age and sunspots after eight weeks, too. The brand recommend gently patting the eye serum onto the eye area in the morning and evening, then massaging the face serum onto the face and neck using a gentle upward motion. Follow with moisturiser and, as always when starting with new retinol formulas, start by applying for 1-2 nights per week and increase gradually as tolerated. Ready to upgrade your skincare routine? Snap up both Triple Retinol Renewal formulas and receive a free, top-selling Perricone MD HP Retinol Recovery Overnight Moisturiser worth £82.
