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Gastric Procedure Alleviates GERD Symptoms in Obesity
Gastric Procedure Alleviates GERD Symptoms in Obesity

Medscape

time01-07-2025

  • Health
  • Medscape

Gastric Procedure Alleviates GERD Symptoms in Obesity

TOPLINE: In patients with obesity, endoscopic gastric remodeling (EGR) — a minimally invasive procedure — is safe and effective in relieving both typical and atypical gastroesophageal reflux disease (GERD) symptoms at 12 months post-procedure, while also reducing proton pump inhibitor (PPI) use. METHODOLOGY: EGR is a minimally invasive alternative to bariatric surgery that reduces gastric volume by approximately 70%, though its effect on GERD symptoms remains unclear. Researchers conducted a prospective cohort study at a tertiary referral bariatric center to examine EGR's effect on GERD symptoms in patients with at least one obesity-related comorbidity. Patients completed GERD and health-related assessments before and 12 months after the procedure. TAKEAWAY: Researchers included 50 patients (mean age, 41 years; mean BMI at baseline, 38.4; 95.8% women; 44% with GERD) who underwent EGR using either endoscopic suturing (16%) or plication (84%). All patients successfully underwent EGR without any serious adverse events. Between baseline and 12 months post-procedure, the mean Reflux Symptom Index score decreased from 5.1 to 3.8 (P = .007) and PPI use from 38% to 20% (P = .047). The presence of a hiatal hernia predicted a greater alleviation of GERD symptoms. IN PRACTICE: 'EGR may be considered a preferred option to co-manage both obesity and GERD, particularly in the lower obesity class,' the authors wrote. SOURCE: This study was led by Pichamol Jirapinyo, MD, MPH, Brigham and Women's Hospital, Boston, and published online in Clinical and Translational Gastroenterology. LIMITATIONS: This study did not include esophageal pH monitoring before or after EGR. Most participants were non-Hispanic women, which may have limited generalizability. Factors such as dietary modifications and medication use were not assessed. DISCLOSURES: The study received no external funding. Several authors reported being consultants; receiving research support, grants, or royalties; and having other ties with pharmaceutical companies. This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

My 600lb Life star Latonya Pottain's tragic final warning from doctors before her death
My 600lb Life star Latonya Pottain's tragic final warning from doctors before her death

Daily Mail​

time20-05-2025

  • Health
  • Daily Mail​

My 600lb Life star Latonya Pottain's tragic final warning from doctors before her death

Tragic My 600lb Life star Latonya Pottain received a chilling final warning from doctors two years before her death aged just 40. Pottain who appeared on season 11 of the TLC show when she weighed 632lbs in 2023, died on Saturday, May 17 at CHRISTUS Highland Medical Center in Shreveport, Louisiana. The preliminary autopsy report found Pottain died from congestive heart failure. Bariatric surgeon Dr Younan Nowzaradan, known as Dr Now, urged Pottain to drastically change her eating habits after she was hospitalized with leg pain after gaining more weight. With a medication and controlled diet she was able to drop to 594lbs but Dr Now had a dire warning for her if she did not lose more weight. He said: 'Now the echocardiogram shows all four chambers of the heart are distended and overstrained. 'Your heart is overstrained because of your weight and your lung capacity is restricted because of your weight. 'So this is a time for you to learn what the healthy eating habits should be. 'You can't go back to what you like to eat and what you consider to be a healthy food. 'We got your heart at a critical place over the past couple of weeks. 'But if you don't keep losing weight your heart is going to get to a critical place very quickly again So change and learn what to do at home because there is something wrong with your eating habit that you're not losing weight 'No excuses, because you're running out of time.' She also memorably clashed with Dr Now over her dislike of the healthy hospital food. Pottain said: 'I haven't really ate since I been here' the Dr responded: 'You're not gonna fade away. You're gonna be fine.' Pottain said: 'I still have to eat something' with Dr Now retorting: 'No, you've already eaten the food that belongs to the next four years ahead of time.' Pottain's brother said he and other family members had visited her at her home on Saturday morning and noticed she was having trouble breathing and told them she was 'extremely uncomfortable'. He added she didn't 'look well.' A nurse later called Pottain's brother to tell them Pottain had called an ambulance to bring her to the hospital because she was going into cardiac arrest, which led to her death. Pottain first appeared on the show in 2023 when her weight had left her mostly bedbound. In harrowing scenes Pottain proclaimed that food 'took the stress away' as her carer brought her breakfast in bed. She said: 'That's what I do to help me cope with things. 'I know the food is unhealthy and not good for me. But with the habit that I have for long, it's hard to change it. I'm disappointed in myself for getting to this place.' She had visited with the show's Doctor Younan Nowzaradan five years prior when she was 482lbs but had left the weight loss program. Despite vowing she was determined to change after battling with her weight her whole life, Pottain struggled with the strict new diet and was seen eating fried food - before gaining weight at her next weigh-in. Last year Pottain took to Facebook to ask for prayers due to her heart issues. She wrote: 'Y'all pray for me my heart not working right and there is nothing more the doctors can do here in Louisiana please keep me lifted.' This year she launched a GoFundMe to get urgent medical care - and revealed her weight was now more than 700lbs. She wrote: 'I'm currently getting close to my highest weight of 740 pounds and I worked extremely hard to get it down. Now I currently weigh about 705 pounds and have been bedridden since June 2024 due to severe health issues. 'After the show aired, I experienced overwhelming backlash, which sent me into a deep depression. My mental health suffered, and I became fearful of undergoing weight loss surgery. This year she launched a GoFundMe to get urgent medical care - and revealed her weight was now more than 700lbs 'In 2023, I moved to Houston, hoping for a fresh start, but instead, I found myself in an abusive relationship while also dealing with the devastating news that my father had been diagnosed with cancer. 'Unable to take the emotional and physical toll, I returned home to Louisiana. Unfortunately, my health continued to decline, and I developed severe sciatica nerve pain, which caused extreme stomach cramps. I was prescribed fentanyl, but my body rejected the medication, leading me to begin therapy. 'Now, I am completely bedridden and unable to get to the hospital because EMTs say transporting me would be a fire hazard due to my weight. Without the ability to work, I have no income to purchase a car or arrange for special medical transportation. 'I am asking for your help to raise funds for: Medical transportation so I can get to the hospital for urgent care 'Proper medical treatment and rehabilitation to regain my mobility 'Basic living expenses since I am currently unable to work 'This has been an incredibly difficult journey, and I truly want to fight for my health and my life. Any amount you can contribute will bring me one step closer to the care I desperately need. If you are unable to donate, please share my story to help me get the assistance I need.' The $20,000 appeal raised a little over $1000.

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