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R&D Investments Fuel Next-Gen Immunomodulator Development Amid Patent Expiry
R&D Investments Fuel Next-Gen Immunomodulator Development Amid Patent Expiry

Associated Press

time04-07-2025

  • Health
  • Associated Press

R&D Investments Fuel Next-Gen Immunomodulator Development Amid Patent Expiry

DUBLIN--(BUSINESS WIRE)--Jul 4, 2025-- The 'Immunomodulator Therapeutics Market, Global, 2024-2030" report has been added to offering. Revenue estimate for the base year 2024 is $93 billion with a CAGR of 9.0% for the study period 2024-2030. This research service offers a comprehensive analysis of the global immunomodulator therapeutics market, specifically targeting inflammatory disorders in the immunology, gastrointestinal (GI), and dermatology segments. The report defines this market through products designed to modify and regulate pathological immune responses, either by inhibiting or suppressing them. It categorizes the market by modality and key indications, providing a 6-year revenue forecast for global immunomodulator prescription drugs, alongside an analysis of key industry participants. The geographic scope encompasses North America, Europe, Asia-Pacific (APAC), the Middle East and Africa (MEA), and Latin America (LATAM), with regional revenue share estimates presented on a best-effort basis. The report also discusses prevalent and emerging business models, analyzes trends in market access and reimbursement for immunomodulator therapies, and offers competitive assessments and revenue share analyses. It examines the factors driving and restraining growth in this space, offering insights into drug development trends, partnerships, and the investment landscape. The report highlights key companies pioneering disruptive virtual care technologies and adjunctive therapies for effective disease management. Based on clinical needs, technological advancements, business models, and competitive dynamics, the report identifies the growth opportunities emerging from this space for market players and stakeholders to leverage. The base year is 2024, and the forecast period is from 2025 to 2030. Growth Drivers Rising Prevalence of Autoimmune and Inflammatory Diseases Increasing prevalence of diseases like lupus, RA, Crohn's disease, and psoriasis is driving demand for immunomodulators like tumor necrosis factor (TNF) inhibitors (e.g., Humira, Remicade) and JAK inhibitors (e.g., Xeljanz). The rapidly aging global population is more susceptible to chronic autoimmune conditions. It is further bolstering demand for treatments tailored to older adults, such as more tolerable biologics. Biotech Advancements Innovations in biotech platforms and advanced modalities such as CGT, bispecific antibodies, and RNA therapies are enhancing the efficacy and safety profiles of immunomodulators and driving the development of next-gen targeted therapies. Carisma Therapeutics Inc. and Moderna, Inc. have collaborated to use Carisma's proprietary CAR-M technology and Moderna's mRNA/lipid nanoparticles (LNP) platform to develop a macrophage engineering approach for autoimmune diseases. Growing Investment in R&D Increased funding from both public and private sectors is accelerating R&D efforts for discovering new therapies and improving existing ones. The NIH allocates significant funding for research on immunomodulatory therapies, fostering innovation. An increasing number of M&A deals demonstrate a growing focus on immunology by big pharma. Success in Oncology and Expanding Applications The success of immunotherapies in oncology has raised awareness and acceptance of similar approaches in treating autoimmune and inflammatory diseases. For example, Roche's Gazyva/Gazyvaro (obinutuzumab), approved in 100 nations for several lymphoma types, is being investigated in the Phase III REGISTRY trial for lupus nephritis. Growth Restraints Immunomodulator Therapeutics: Growth Restraints, Global, 2025-2030 Stringent Regulatory Processes: Stringent regulatory processes for immunomodulatory treatment approval or the development of novel mechanisms of action, globally, can cause delays in market access and raise development expenses for pharmaceutical companies. Moreover, inadequate reimbursement/insurance coverage globally may deter wide-scale adoption, especially in public health systems or regions with limited healthcare resources. Inadequate coverage of high-cost new drugs would increase the expenses of managing long-term conditions, impacting patient compliance and market growth. Potential Adverse Effects and Safety Concerns: Immunomodulators may have serious adverse effects, such as an elevated risk of infections and autoimmune responses. For example, checkpoint inhibitor use in autoimmune disease is linked to immune-related side effects that need to be carefully managed. Adverse outcomes and safety risks may lead to regulatory actions such as market recalls, limited prescriptions, and reduced patient confidence, challenging market uptake. Patent Expiry: Expiry of blockbuster drug patents is leading to the introduction of biosimilars and generic versions, intensifying market competition, resulting in price erosions, and leading to a loss of sales revenue for branded products. For example, AbbVie's blockbuster Humira, approved for several autoimmune conditions like RA, psoriasis, Crohn's disease, and ankylosing spondylitis, started facing biosimilar competition in 2023. Patient Inconvenience: Biotech advancements have facilitated the development of effective biologic therapies; however, therapy administration requires frequent injections or infusions, making it challenging for patients to adhere to their treatment regimens. It may affect overall patient satisfaction and treatment discontinuation. The Impact of the Top 3 Strategic Imperatives on the Immunomodulator Therapeutics Industry Disruptive Technologies Why: There is an increasing incidence of autoimmune diseases, particularly impacting women. Limitations in existing therapies demand more targeted applications. Analyst Perspective: A new wave of drug classes (JAK1, IL, calcineurin, TNF?, TYK2, PDE4), across small molecules, biologics, and cell and gene therapies, will emerge, offering enhanced efficacy and safety profiles for treating autoimmune and inflammatory conditions. There will be a growing trend towards combination therapies that utilize multiple mechanisms of action to achieve better clinical outcomes. Internal Challenges Why: The industry is moving toward an extended patent cliff, with several revenue-generating blockbuster drugs like Humira and Stelara losing their exclusivity, leading to revenue losses and increased biosimilar competition, creating an urgent need for pipeline growth, and driving increased research and development (R&D). Resource demands for R&D can strain budgets, especially for smaller biotech firms. Analyst Perspective: Companies may increasingly seek strategic partnerships to share costs and risks, fostering innovation through collaborative R&D efforts. Companies that emphasize unique value propositions in these strategic alliances will be better positioned to access markets/fair pricing with drugs like JAK inhibitors and women-specific therapies. Payers will scrutinize clinical costs and patient outcomes to ensure balance and sustainable reimbursement models that reflect indication-specific needs and improve affordability. Transformative Megatrends Why: Healthcare systems are under pressure to contain current and future spending. Healthcare plan sponsors are considering their next moves as governments contemplate the impact of the Inflation Reduction Act (IRA) 2022, and associated price cuts in the United States. Analyst Perspective: Firms will invest in adaptive trial designs for evidence generation to expedite approvals for novel MoA-based targeted therapies, advancing precision medicine going forward. Pharma companies will utilize diagnostic delivery services to improve patient access by partnering with telehealth/AI-enabled symptom monitoring platforms (e.g., Ada Health) and focus on an emerging market-expansion strategy. Focus on predictive convergence of drugs and digital therapeutics will likely personalize medicine and improve experiences and outcomes. Scope of Analysis Ecosystem in the Immunomodulator Therapeutics Sector Growth Opportunity Universe in Immunomodulator Therapeutics Sector Key Competitors For more information about this report visit About is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends. View source version on CONTACT: Laura Wood, Senior Press Manager [email protected] For E.S.T Office Hours Call 1-917-300-0470 For U.S./ CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900 KEYWORD: INDUSTRY KEYWORD: BIOTECHNOLOGY PHARMACEUTICAL HEALTH SOURCE: Research and Markets Copyright Business Wire 2025. PUB: 07/04/2025 06:43 AM/DISC: 07/04/2025 06:43 AM

Rising Popularity of Remote Work Elevates Demand for Caravans with Modern Amenities
Rising Popularity of Remote Work Elevates Demand for Caravans with Modern Amenities

Associated Press

time03-07-2025

  • Automotive
  • Associated Press

Rising Popularity of Remote Work Elevates Demand for Caravans with Modern Amenities

DUBLIN--(BUSINESS WIRE)--Jul 3, 2025-- The 'Caravans Market Outlook 2025-2034" report has been added to offering. Caravans Market is valued at USD 14.9 billion in 2025. Further the market is expected to grow by a CAGR of 5.6% to reach global sales of USD 24.4 billion in 2034 The caravans market has experienced steady growth as consumers increasingly seek flexible and comfortable travel options. Caravans, also known as travel trailers or camper vans, offer a home-on-wheels experience, allowing travelers to explore various destinations without compromising on comfort or convenience. This market encompasses a wide range of products, from compact teardrop trailers to luxurious motorhomes, catering to different budgets, preferences, and travel needs. One of the key trends shaping the caravans market is the rising demand for eco-friendly and energy-efficient models. Many manufacturers are integrating solar panels, energy-efficient appliances, and sustainable materials into their designs. Additionally, the popularity of remote work and digital nomad lifestyles has driven the demand for caravans equipped with workspaces, reliable internet connectivity, and modern amenities. This trend has encouraged innovation in layout design, storage solutions, and off-grid capabilities. Regionally, North America and Europe have been the largest markets for caravans, supported by a well-established camping culture, extensive road networks, and strong leisure travel industries. Meanwhile, the Asia-Pacific region is emerging as a key growth area, driven by rising disposable incomes, an expanding middle class, and growing interest in outdoor recreation. As consumer preferences evolve and manufacturers continue to innovate, the caravans market is poised for sustained growth and diversification. Key Insights Caravans Market Your Takeaways From this Report Key Attributes: Companies Featured Caravans Market Segmentation By Type By Price By Application By Geography For more information about this report visit About is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends. View source version on CONTACT: Laura Wood, Senior Press Manager [email protected] E.S.T Office Hours Call 1-917-300-0470 For U.S./ CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900 KEYWORD: INDUSTRY KEYWORD: OTHER AUTOMOTIVE RECREATIONAL VEHICLES PERFORMANCE & SPECIAL INTEREST AUTOMOTIVE SOURCE: Research and Markets Copyright Business Wire 2025. PUB: 07/03/2025 12:28 PM/DISC: 07/03/2025 12:28 PM

Agriculture Imaging Sensor Market Size, Share, Trends, Analysis, and Forecast 2025-2034
Agriculture Imaging Sensor Market Size, Share, Trends, Analysis, and Forecast 2025-2034

Associated Press

time03-07-2025

  • Business
  • Associated Press

Agriculture Imaging Sensor Market Size, Share, Trends, Analysis, and Forecast 2025-2034

DUBLIN--(BUSINESS WIRE)--Jul 3, 2025-- The 'Agriculture Imaging Sensor Market Size, Share, Trends, Analysis, and Forecast 2025-2034 | Global Industry Growth, Competitive Landscape, Opportunities, and Challenges' has been added to offering. The global agriculture imaging sensor market is projected to reach a value of USD 6.4 billion by 2034, growing at a CAGR of 15.7% from USD 1.7 billion in 2025. This research aids top management, strategists, business developers, sales managers, and investors by offering global and regional market sales data, insights on market trends, competitive analysis through SWOT, and financial projections to navigate and invest strategically in the agriculture imaging sensor market. This growth reflects the increasing demand for advanced monitoring solutions in precision agriculture. Imaging sensors like multispectral, hyperspectral, and thermal sensors capture high-resolution imagery and crucial data, providing insights into crop health, soil conditions, and environmental factors. These technologies enhance farmers' ability to detect diseases, pests, and nutrient deficiencies, optimize irrigation systems, and ultimately improve crop yields. As agriculture becomes more data-driven, imaging sensors' role in this technological evolution is set to expand significantly. The market is currently witnessing notable advancements in sensor technology. Multispectral and hyperspectral sensors' increasing precision allows farmers to gather more detailed data on plant health and soil conditions. These sensors are increasingly integrated with drones, UAVs, and satellite systems to facilitate large-scale monitoring, improving efficiency and coverage. The proliferation of IoT-based systems further enhances real-time data collection and analysis capabilities. Additionally, incorporating AI and machine learning with sensor data is yielding actionable insights, empowering farmers with data for informed decision-making regarding crop management and resource allocation. Looking towards 2025 and beyond, the market anticipates further innovation in sensor miniaturization and affordability, extending these technologies' accessibility to small-scale farmers. Integration with AI-powered analytics platforms paves the way for predictive analytics that will enable anticipation of crop needs and environmental changes. The focus on sustainable and climate-resilient agriculture is rising, prompting demand for advanced imaging sensors to monitor environmental variables and improve resource efficiency. With the increasing adoption of smart farming practices, imaging sensors will become even more critical in optimizing operations and boosting yields. Key Market Trends: Market Drivers: Market Challenges: Market Segmentation: Key Attributes: Companies Featured For more information about this report visit About is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends. View source version on CONTACT: Laura Wood, Senior Press Manager [email protected] For E.S.T Office Hours Call 1-917-300-0470 For U.S./ CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900 KEYWORD: INDUSTRY KEYWORD: TECHNOLOGY PHOTOGRAPHY AGRICULTURE NATURAL RESOURCES SOURCE: Research and Markets Copyright Business Wire 2025. PUB: 07/03/2025 07:11 AM/DISC: 07/03/2025 07:11 AM

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