Latest news with #digitaltwins
Medscape
04-07-2025
- Health
- Medscape
Digital Twins: Medicine's New Crystal Ball?
Digital twins are rapidly emerging as powerful tools in personalized medicine and beyond. In healthcare, they serve as virtual representations of a patient's body, body parts, specific organs, and systems, such as the circulatory and nervous systems. Functional modeling of the state and behavior of the body or its components has the potential to provide information for clinical and research applications. The goal is to simulate how an organ, system, or even the entire body responds to stimuli and circumstances of clinical relevance to the patient, thereby deriving useful conclusions. These models may be descriptive, predictive, prescriptive, or even generative, capable of filling in missing or unavailable data. A central challenge is accurately replicating the physicochemical, physiological, anatomical, and, when needed, psychological attributes relevant to each specific use case. Building clinically useful digital twins depends on integrating diverse data sources, which is a technically complex task. However, when successful, it enables a dynamic 'dialogue' with the model to evaluate its current state, forecast evolution, and simulate responses to interventions such as therapies. It is important to emphasize that digital twin simulations are tailored to individual patients — they do not represent a generic or archetypal patient but instead aim to create a personalized model for a specific individual. One example is a project led by the Spanish National Cancer Research Centre (CNIO), which is developing digital twins of women with advanced cancer using artificial intelligence. This initiative, titled 'High-Definition Oncology in Women's Cancer,' is part of the Precision Medicine Infrastructure Associated With Science and Technology program. These digital twins consist of multiple layers of information integrated into a single model that reflects reality for a specific application. In the aforementioned project, a wide range of data were incorporated into the digital twin models, spanning tumor metabolism, gene and protein expression, physiological indicators such as circadian rhythms, heart rate, and physical activity, emotional well-being, and conventional clinical data from diagnostics to treatment protocols. Adding more 'layers' of information enhances the model complexity and accuracy, enabling incremental improvements and expanded functionality. A notable innovation in this case is the biological clock model developed by the CNIO, which estimates a patient's biologic age. This can help assess whether biologic aging accelerates or slows during disease progression, providing insight into the effect of treatment. This may guide clinicians in adjusting treatment intensity or modifying therapeutic combinations according to the patient's evolving biologic state. The layers of information used and their integration are key aspects of each type of digital twin, ensuring that it is not only functional but also clinically relevant. In many ways, digital twins serve as 'maps,' both literal and figurative. In the most direct sense, they can guide the planning of physical interventions such as surgical procedures. Broader Applications In addition to simulating the effects of therapies, digital twins can model the natural progression of diseases and support long-term care planning. They may help anticipate the onset of certain conditions, particularly hereditary diseases, when risk factors are present but symptoms have yet to appear. These models offer valuable tools for proactive risk prevention and management. In the context of prevention, the ability to present a stronger, data-driven case — even if derived from simulations — could help persuade patients and improve adherence to preventive care guidelines. Integration With Medical Devices From a certain perspective, digital twins resemble a technology-driven 'crystal ball.' Once refined, these models could allow clinicians to explore alternative therapeutic scenarios and identify the most effective treatment strategies. This minimizes reliance on trial and error, enabling faster data-driven decisions in a controlled simulation environment, a kind of clinical sandbox. A key area of synergy lies between the digital twins and medical devices. Wearable technologies, for instance, can supply real-time or periodic health data that dynamically update a patient's digital twin. Conversely, digital twins can enhance the medical device field by enabling the optimization of device configurations or implant placements. Their integration into the body and potential physiological effects can be modeled and simulated in advance, allowing for more precise and personalized interventions. These models also help to synthesize and manage large volumes of complex data. By serving as intelligent filters, they reduce the cognitive load on clinicians, offering clear visualizations and simulations that support more confident decision-making, especially in complex or uncertain clinical situations. Applications and Regulatory Considerations Digital twins hold promise across a wide range of medical applications, from early diagnosis, prognosis, and personalized therapy selection to treatment monitoring and relapse prevention. In fields such as neurology, cardiology, and oncology, these models have already shown potential. Digital twins have already been applied in neurology, cardiology, and oncology. Focusing on Spain-based developments, two recent advances featured by Univadis Spain , a Medscape Network platform, stand out: One involves using digital twins for research on the human brain to uncover mechanisms linked to psychosis remission, and the other demonstrates the use of digital twin improvements in the diagnosis of premature ventricular contractions. While the field is evolving rapidly, it remains in its early stages. Although technical hurdles and regulatory complexities are expected, the long-term potential is significant. Digital twins could enable faster and safer evaluations of multiple treatment paths and support virtual experimentation in a risk-free environment. One major challenge is clinical validation. Digital twins must be tested with real-world longitudinal data and demonstrate that their predictions provide added value compared to current clinical guidelines. Equally crucial is the development of interoperable, cross-border data infrastructure that enables scalable, coordinated adoption across healthcare systems worldwide. A final and crucial aspect to consider is data privacy, ownership, and ethical use of digital twins. Beyond the data itself, fundamental questions arise about digital twin models: Who owns a person's digital twin? Should these models be transferable, and if so, under what conditions? Informed consent is central to addressing these issues and ensuring the responsible use of digital twin technologies in clinical practice. The use of digital twins in clinical trials is already being explored, and their potential extends further to medical training and patient education, particularly in explaining therapeutic options. As technology evolves, the range of future applications continues to expand.
Yahoo
03-07-2025
- Business
- Yahoo
Cadence Announces Second Quarter 2025 Financial Results Webcast
SAN JOSE, Calif., July 03, 2025--(BUSINESS WIRE)--Cadence (Nasdaq: CDNS) will hold its second quarter 2025 financial results webcast on Monday, July 28, 2025. Participating in the webcast will be Dr. Anirudh Devgan, president and chief executive officer, and John Wall, senior vice president and chief financial officer. The webcast will begin Monday, July 28, 2025, at 2:00pm Pacific Time. An archive of the webcast will be available online from 5:00pm Pacific Time on July 28, 2025, until 5:00pm Pacific Time on Monday, September 16, 2025, at About Cadence Cadence is a market leader in AI and digital twins, pioneering the application of computational software to accelerate innovation in the engineering design of silicon to systems. Our design solutions, based on Cadence's Intelligent System Design™ strategy, are essential for the world's leading semiconductor and systems companies to build their next-generation products from chips to full electromechanical systems that serve a wide range of markets, including hyperscale computing, mobile communications, automotive, aerospace, industrial, life sciences and robotics. In 2024, Cadence was recognized by the Wall Street Journal as one of the world's top 100 best-managed companies. Cadence® solutions offer limitless opportunities—learn more at © 2025 Cadence Design Systems, Inc. All rights reserved worldwide. Cadence, the Cadence logo and the other Cadence marks found at are trademarks or registered trademarks of Cadence Design Systems, Inc. All other trademarks are the property of their respective owners. Category: Financial View source version on Contacts For more information, please contact: Cadence Investor Relations408-944-7100investor_relations@
The National
03-07-2025
- Business
- The National
Can AI avatars ensure that a CEO has eyes and ears everywhere?
Having an avatar has seemingly always been for those immersed in video games and social media. It was confined to fun and games, until now. Sebastian Siemiatkowski, chief executive of Klarna, and Zoom chief executive Eric Yuan recently made news when they sent their AI avatars to take their place at quarterly earnings meetings. Better known as digital twins, these AI creations use data to build a visual representation of a real human being and mimic their speech and behaviour. In short, it is a virtual body double. Are business leaders finally getting to a point where they can be in two places (or more) at once? The reason this is possible is the emergence of agentic AI systems that have memory and are self-controlled, contextually aware, and capable of aligning goals. Such AI agents do not simply carry out orders, but know why a decision was made, how organisational dynamics work, and when it is time to act or escalate. To CEOs, this means a strategic leverage unseen before: the ability to triage complexity, extend presence over geographies and functions as well as provide leadership continuity at a machine-speed. The chief executive will be informed by their avatar, but we believe that the line will be drawn at decision making. Yes, the download that the CEO takes from their digital twin will be considered, but no true decision on the direction of a company, staffing, or choice of products or services can be made by an avatar. This is where the CEO must insert themselves and deliver all decisions and messages as themselves, as a human. Real-life implications of digital twins The global digital twin market is estimated to reach $155.84 billion by 2030, according to Grand View Research estimates. In fact, when speaking of advanced industries, about 75 per cent of them have already adopted some form of digital twin technology, a McKinsey study found. The vast majority of this, however, is product simulations and service twins where companies can test and practice scenarios in controlled environments before going to market, not twins of actual humans. The benefits range from faster development, safer products, and greater innovation, to cost savings and greater predictions of outcomes. But, what about a human digital twin? Before any technology is truly embraced, there must be a proof of concept. With the likes of Mr Siemiatkowski and Mr Yaun successfully using digital avatars (albeit in closed one-off internal meetings) the technology is likely to gain momentum across industries. We already see people like Otter chief executive Sam Liang, LinkedIn co-founder Reid Hoffman, and Khosla Ventures managing director Keith Rabois, all using AI digital twin avatars. The drive behind this? Time and availability. In some cases, digital twins have already cut total development times by 20 per cent to 50 per cent, and resulted in 25 per cent less quality issues on entering production, according to the McKinsey report. If these numbers stay true, or probably increase, there will be no stopping this technology from spreading across industries around the globe. When CEOs find that there is an increase in safety, production times are lessened, R&D time and expense goes down, and their profits go up from using digital twins, why would they not use digital twin technology? As more and more leaders around the globe see this technology used successfully, they will follow suit with a digital version of themselves. They will decide what meetings they will need to attend and then send their digital self to the rest. There will be no more double booking or missed opportunities. They can attend every meeting and have eyes and ears everywhere. They no longer have to rely on notes from someone else. The digital twin avatar will report back based on the data input it receives. The ethical dilemma As this technology spreads, we will begin to ask where the physical world ends and the digital world begins. Is there too much of a blur? Is it the moral responsibility of a leader to inform everyone before a meeting that an avatar will attend on their behalf? Consequently, will the people required to be in that meeting feel disrespected that the CEO did not physically show up? Leaders will need to struggle with this continuously. The follow-up from a digital twin also raises ethical concerns. How do you ensure that inherent biases are accounted for? As a human you can read facial expressions, notice that someone spends a lot of the meeting off camera, or appears to be having side conversations while the meeting is taking place. Will the avatar have these same instinctual observations and report back? As the technology evolves so will the demands put upon it by its human creators. This new power a chief executive can harness will be accompanied with an additional dimension of ethical and fiduciary responsibility. The digital twin of a CEO should have well-established guardrails and transparency, traceability and accountability of all the decisions that it might be involved in and influence. Auditability of agentic actions and alignment to corporate governance practices should be guaranteed to the boards and shareholders, not black-box behaviours. The ethical requirement is not simply to enable digital avatars, but to root them in human control, corporate responsibility and the interests of the business in the long term. This technology will become commonplace throughout the corporate world. But it will be up to each individual leader to decide what responsibilities they abdicate to a machine and which they keep for themselves. It will be interesting to see this evolution and monitor what becomes of businesses and the reputations of leaders that send digital twins to do their work.
Yahoo
01-07-2025
- Business
- Yahoo
Grid Dynamics Holdings Releases Intralogistics Optimization Starter Kit for the NVIDIA
Grid Dynamics Holdings, Inc. (NASDAQ:GDYN) is one of the 12 Small Cap Stocks with High Upside Potential. On June 11, Grid Dynamics released an intralogistics optimization starter kit for the NVIDIA Omniverse. The solution promises improved warehouse efficiency and a reduction in labor costs. Intralogistics operators can now create digital twins of warehouses, distribution centers, and production facilities. The digital twins facilitate potential layouts and what-if analyses. The kit ensures that the digital twins integrate historical order patterns, the facility's physical layout, and inventory management structures. A close-up of a server running a cloud-native platform, symbolizing the power of the software-as-a-service (SaaS) business area. Customers of Grid Dynamics believe that building digital twins brings a lot of value to their systems. To meet growing demand, the company is expanding its portfolio of supply chain and smart manufacturing solutions. Grid Dynamics Holdings, Inc. (NASDAQ:GDYN) is a technology consulting and advanced analytics service. Its services include a cloud platform and product engineering services to the retail, technology, media, telecom, and finance sectors. While we acknowledge the potential of GDYN as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: The Best and Worst Dow Stocks for the Next 12 Months and 10 Unstoppable Stocks That Could Double Your Money. Disclosure: None. Sign in to access your portfolio
Arab News
07-06-2025
- Business
- Arab News
SAS digital twins transform manufacturing
SAS is poised to help transform critical processes in the manufacturing industry with enhanced digital twins that combine SAS' powerful AI and advanced analytics with Unreal Engine from Epic Games. With these digital twins, manufacturers like Georgia-Pacific can experiment with new strategies in simulated digital worlds, then take the best approaches and implement them in the real world. One of the world's leading manufacturers of paper and wood-based building products, GP is piloting these enhanced digital twins at its Savannah River Mill, which manufactures napkins, paper towels and toilet tissue. GP is leveraging SAS' technology to optimize its use of automated guided vehicles and other processes.
