Latest news with #pediatrichealth
Yahoo
2 days ago
- Business
- Yahoo
Mesoblast Limited (MESO) Launches First Cell Therapy for Children
We recently compiled a list of Mesoblast Limited stands tenth on our list and has launched the first cell therapy for children. Mesoblast Limited (NASDAQ:MESO) is among the best mid-cap stocks to buy according to billionaires. It is a global leader in developing allogeneic (off-the-shelf) cellular medicines using its proprietary mesenchymal lineage cell technology. The company targets severe inflammatory diseases that lack effective treatment options. Its lead product, Ryoncil (remestemcel-L), became the first and only FDA-approved mesenchymal stromal cell therapy for children with steroid-refractory acute graft versus host disease (GVHD) in March 2025. Following approval, Mesoblast Limited (NASDAQ:MESO) rapidly launched the drug, partnering with over 25 major U.S. transplant centers and securing insurance coverage for over 250 million lives, including mandatory Medicaid coverage in all states. Ryoncil now benefits from seven years of orphan drug exclusivity and biologic exclusivity until 2036, with intellectual property protection through 2044, effectively limiting competition. The approval marks the foundation of the business's broader pediatric inflammatory disease franchise, with plans to expand Ryoncil's use to additional pediatric and adult indications. A healthcare professional examining T-cell immunotherapy. The corporation's manufacturing processes allow scalable production of consistent cell therapies without the need for donor-recipient matching, simplifying access and logistics. The company is also advancing other key candidates: Revascor (rexlemestrocel-L) for ischemic heart failure, which is on track for FDA submission by the end of 2025 under RMAT designation, and a Phase 3 program for rexlemestrocel-L targeting chronic discogenic low back pain, offering a non-opioid alternative for patients. While we acknowledge the potential of MESO as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: The Best and Worst Dow Stocks for the Next 12 Months and 10 Unstoppable Stocks That Could Double Your Money. Disclosure: None. Sign in to access your portfolio
CBS News
3 days ago
- Health
- CBS News
2 years after brain swelling scare, Shorewood toddler is back to her spunky self
Four-year-old Sydney Marcus is a fast-moving, spunky kiddo. "[She was] just very chatty, mobile, running around, learning, just like a little sponge," Sydney Marcus' mom, Britta Marcus, said. But one night two years ago, Sydney Marcus flipped like a light switch. "It was kind of like a one-in-a-million fluke, essentially and her body reacted to it and started attacking itself," Britta Marcus said. She says her toddler went to bed with a run-of-the-mill fever, cold and runny nose — and didn't wake up. "It was just a overnight light switch of where she went from like a healthy, normal kid, and woke up unresponsive," Britta Marcus said. Sydney Marcus was rushed to the hospital where doctors determined a rare, inflammatory condition called cerebellitis was causing swelling, fluid and pressure build-up in her brain. The cause was a combination of common cold viruses. "It's extremely rare. I mean, there's there some case reports that we'll talk about it being one in 500,000 and even one in a million, if million, it's extremely rare," Sydney Marcus' neurosurgeon at Children's Minnesota, Dr. Meysam Kebriaei, said. Sydney Marcus underwent two emergency surgeries at Children's Minnesota. "They removed a small piece of her skull and put a drain into her fluid space to try to relieve the pressure that way," Kebriaei said. The next challenge came post-surgery: rehab. She had to relearn everything — from walking to talking to swallowing her food. "It was literally starting over, like, with a newborn," Sydney Marcus' dad, Ross Marcus, said. "From a neurosurgical perspective, she's 100% and, like, that's, that's the emotional piece, right? Like, we're incredibly lucky to be in this situation." Thanks to physical therapy and rehab, Sydney Marcus is now returning to her spunky self. "I think she's going to have a bright future," Kebriaei said. These days, Sydney Marcus is busy blowing bubbles and chasing her two older sisters. "We were just could not have been more impressed, truly, with the care, the diversity of thought and the consistency of like, their presence and their support of our family," Ross Marcus said. The Marcus family says it's that support that saved their daughter's life. "Giving people hope is something you don't have the opportunity to do a lot, and in those darkest moments, is what really pushes you through and really gets you through and helps you fight for your child, right? And if we can provide that, I mean, we will do it all day long," Ross Marcus said. Doctors say cerebellitis is rare and even more rare in children. Doctors reiterate a common cold is typically nothing to worry about.
Daily Mail
7 days ago
- Health
- Daily Mail
HGTV star Jasmine Roth shares major health update after daughter's severe sleep apnea diagnosis
HGTV star Jasmine Roth is known for transforming homes on her show Help! I Wrecked My House, but she recently opened up about a different transformation - her daughter's health. In a heartfelt update shared through an interview with Future of Personal Health, Roth revealed that five-year-old Hazel underwent tonsil and adenoid reduction surgery in November 2023. And now, Hazel is doing much better. 'Hazel is sleeping like a champ!' Roth shared. 'She has no issues, just goes to sleep, sleeps through the night, and wakes up in the morning, which anybody with a child knows is a big deal.' Jasmine admitted she had no idea children could even experience sleep apnea. Hazel showed signs as early as six months old, but the condition remained undiagnosed until she was three. The diagnosis came years after going undetected, despite heavily affecting the entire family's sleep and wellbeing. In an Instagram post from November 2023, Roth spoke about her daughter Hazel's journey after she was first diagnosed of pediatric sleep apnea. It happened after a sleep study confirmed she had borderline severe sleep apnea, which caused her to wake up more than seven times per hour and experience drops in oxygen levels. Before her diagnosis, Jasmine and her husband Brett noticed something was off. 'A few months ago, we noticed a weird breathing/snorting thing happening,' Roth shared on Instagram at the time. Despite Hazel seeming to sleep fine at times, a visit to a pediatric ENT specialist and a follow-up sleep study revealed the severity of her condition. Jasmine recalled, 'Her tonsils were touching… and the x-rays showed her adenoids were also enlarged.' Choosing surgery wasn't a decision they made lightly. 'We opted to do a sleep study instead of jumping right into surgery,' she wrote. But after the results came in, it became clear that surgical intervention was the best path forward. It was found that Hazel's tonsils were touching and that her adenoids were enlarged She praised the care Hazel received at CHOC Children's Hospital and the compassion shown by the medical staff. 'If I ever need surgery, I want to go there,' she said, giving a special shoutout to Dr. Bhatt and the team. The surgery was a success. Just weeks later, Hazel began sleeping soundly through the night - for the first time in her life. 'Like most parents, we wish we'd caught it sooner,' Roth said. 'But once we understood what was going on, everything moved quickly.' In the midst of this health scare, the Roth family also experienced a joyful - though intense - milestone. In September 2024, Jasmine gave birth to their second daughter, Darla, one month early in what she described as a dramatic, near-roadside delivery. Roth shared that the surgery was a success and that Hazel was sleeping through the night for the first time in her life Thankfully, the new addition arrived as Hazel's health was already improving drastically. After spending 15 days in the NICU, Darla is now healthy and bonding with her big sister. With so many personal developments, it's no surprise Jasmine took a step back from filming Help! I Wrecked My House over the past year. But fans won't have to wait much longer as a new season, filmed in the Roths' new home state of Utah, is set to premiere sometime in Fall 2025.
Zawya
29-06-2025
- Health
- Zawya
Democratic Republic of the Congo (DRC): New initiative to eliminate Human Immunodeficiency Virus (HIV) in children ‘a beacon of hope'
The Democratic Republic of the Congo (DRC) has launched a bold new national initiative aimed at eliminating AIDS among children by 2030 – a move hailed by the United Nations as 'a beacon of hope' amid growing global funding constraints. 'Our country can no longer tolerate children being born and growing up with HIV, when tools exist to prevent, detect and effectively treat this infection,' President Félix Tshisekedi declared at a recent government conference in the south-eastern Lualaba province, as he launched the five-year initiative. Backed by an initial commitment of $18 million in national funds, the Presidential Initiative to End Pediatric AIDS will focus on political leadership, systems strengthening and inclusive healthcare access particularly for children, adolescents, and pregnant women. It also aligns well with DRC's global commitments under the Sustainable Development Goal 3 (SDG 3) to ensure healthy lives and promote well-being for all. Children lagging behind The initiative marks a renewed commitment by the DRC to address children's extremely limited access to HIV prevention and treatment services. While the DRC has made notable strides in adult HIV response – 91 per cent of adults living with HIV now have access to antiretroviral treatment – children continue to lag far behind. Only 44 per cent of children living with HIV in the country currently receive lifesaving treatment, a figure that has remained unchanged for over a decade. Every year, thousands of Congolese children are still infected, often due to a lack of screening among pregnant women, depriving the health system of a crucial opportunity to prevent mother-to-child transmission as well as saving the mother's live. 'The eradication of paediatric AIDS is a moral imperative, an imperative of social justice and an indicator of dignity,' Mr. Tshisekedi said. Four core priorities The Presidential Initiative targets four core areas: Improving early detection and treatment of HIV for children, adolescents and pregnant women Preventing new infections in children, adolescents and mothers Guarantee systematic and immediate treatment for those diagnosed Remove structural barriers hindering young people's access to health services A breath of fresh air The UN Joint Programme on HIV/AIDS (UNAIDS) praised the initiative as an example of the national leadership needed to close critical gaps in global HIV response. Susan Kasedde, UNAIDS Country Director in the DRC, commended the initiative as 'a breath of fresh air' at a time when global development financing is under strain. 'At a time when development financing is experiencing turbulence and risk jeopardizing the systems that support the most vulnerable, President Tshisekedi's leadership initiative is a beacon of hope,' she said. According to UNAIDS, recent funding cuts are threatening critical HIV services, with stock of medication and condoms feared to run out within months. Key areas like antenatal testing, paediatric treatment and data quality monitoring have also been impacted. Distributed by APO Group on behalf of UN News.
Medscape
27-06-2025
- Health
- Medscape
Food Allergies Less Common in Children With Cystic Fibrosis
TOPLINE: In the US, children with cystic fibrosis (CF) were significantly less likely to develop food allergies than children without CF. However, boys and children not receiving pancreatic enzyme replacement therapy had disproportionately higher rates of food allergy. Determination of food allergy is important in CF because nonspecific gastrointestinal symptoms associated with CF may be misdiagnosed as food allergy. METHODOLOGY: Researchers conducted a retrospective study to observe the prevalence, associated factors, and phenotypes of food allergies in children with CF. They included 289 children with CF (mean age, 11.93 years; 51.21% boys) who had at least one clinical encounter between August 2021 and August 2022 at two academic institutions in St. Louis. The prevalence of food allergy in children with CF was compared with that in a nationally representative 2018 sample of children without the condition. TAKEAWAY: The prevalence of food allergy in children with CF was 3.81% (95% CI, 1.91%-6.71%), significantly lower than the 7.60% (95% CI, 7.10%-8.10%; P = .015) reported in children without CF. Compared with boys with CF (6.08%), girls with CF had a significantly lower prevalence of being diagnosed with food allergy (1.42%; P = .038). Children who did not receive pancreatic enzyme replacement therapy had a higher prevalence of food allergy than those who received it (9.09% vs 2.25%; P = .020). IN PRACTICE: 'These results highlight the importance of thorough investigation into FA [food allergy] labels in patients with CF, particularly as this population may benefit from the incorporation of high-protein, high-fat allergens in the diet,' the study authors wrote. SOURCE: Stephanie Leeds, MD, with the Yale University School of Medicine, New Haven, Connecticut, was the corresponding author of the study, which was published online on June 21 in the Annals of Allergy, Asthma & Immunology. LIMITATIONS: This study was limited by its retrospective design, a small number of food allergy cases, the use of criteria to confirm food allergies that differed from those in a prior study, and potential gaps in electronic medical records. DISCLOSURES: Some authors reported providing consultation services to or receiving funding or scholarships from various pharmaceutical companies or organizations. This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
