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The Gut-Skin Connection
The Gut-Skin Connection

WebMD

time07-07-2025

  • Health
  • WebMD

The Gut-Skin Connection

You've probably heard that the gut and the brain communicate with each other, but do you know about the gut-skin connection? Issues with gut health may be showing up on your face as rosacea, and rosacea may indicate you have gastrointestinal disease. What Is Rosacea? Rosacea is a skin condition that affects the face. It's marked by inflammation that causes reddened skin, visible blood vessels or a rash on the nose and cheeks, and skin thickening. Rosacea can also affect the eyes, making them sore, watery, or dry. An estimated 14 million people in the U.S. have rosacea. Those with fair skin, women, and midlife and older adults are more prone to rosacea. Rosacea symptoms can come and go, and there's no cure. However, there are ways to manage rosacea with diet and lifestyle habits, including supporting gut health. Inflammation Is the Source Inflammation contributes to skin redness and rash in rosacea. Like the gut, the skin has its own community of microbes (mostly bacteria), which may become disturbed and cause rosacea flare-ups. Rosacea may also be triggered by circumstances that cause blood vessels in the face to open up and result in reddened skin, including high temperatures, strong sunlight, alcohol, hot beverages, and spicy foods. The source of the inflammation for rosacea may also lie far below the skin's surface. As disconnected as the two may seem, the gut plays a role in rosacea, according to a recent analysis. Gut bacteria help regulate inflammation throughout the body, including in the skin. Gastrointestinal conditions can throw off the ratio of good to bad bacteria in the gut, allowing inflammatory substances to get into the bloodstream and result in rosacea symptoms. People with rosacea have a higher rate of infection with H. pylori bacteria, which causes bloating, pain, and stomach ulcers, celiac disease, small intestinal bacterial overgrowth (SIBO), or inflammatory bowel disease (IBD). Trying these suggestions may have you well on your way to a healthy gut and healthy skin! If you have rosacea and you also suffer from ongoing abdominal pain or diarrhea, or bloody stools, ask your doctor about your gastrointestinal symptoms. They may be connected to your rosacea. Reducing Rosacea Risk Every case of rosacea is unique. In addition to avoiding foods and lifestyle habits that bother your rosacea, you may benefit by supporting your gut health. Here's how. Eat a high-fiber diet. Include a variety of plant foods, such as whole and lightly processed grains, fruits, vegetables, legumes, and lentils, to include 28 grams of fiber daily on a 2,000-calorie eating plan. Fiber feeds beneficial gut bacteria that produce compounds that fight inflammation and help prevent substances that trigger rosacea from getting into the bloodstream. Consider probiotics: There's some preliminary evidence that taking probiotics, live bacteria that provide health benefits when taken in adequate amounts, may play a role in managing rosacea. However, the effects of probiotic supplements on gut health are strain-specific, which means you must take the type of probiotic that studies prove have the desired effect on gut health, not just any probiotic pill from your pharmacy or the internet. If you're considering probiotic supplements, talk with your doctor or nurse practitioner before taking them.

The Best Way to Clear Up Rosacea: Treatments That Actually Work
The Best Way to Clear Up Rosacea: Treatments That Actually Work

Health Line

time04-07-2025

  • Health
  • Health Line

The Best Way to Clear Up Rosacea: Treatments That Actually Work

Key takeaways Treatment options for rosacea include topical products, eye drops, oral medications, and light therapy. Identifying and avoiding personal triggers can help manage rosacea flare-ups. Some possible triggers include stress, sunlight, certain foods, and harsh skin care products. Developing a gentle skin care routine can also help minimize symptoms of rosacea. Overview Rosacea is a chronic condition that affects skin of your face. It's not life-threatening, but it can be uncomfortable. Rosacea can cause redness, pimples, pustules, or dilated blood vessels on your face. In some cases, skin on your nose or other parts of your face may thicken. Rosacea might also cause inflammation of your eyes or eyelids. Getting treatment for rosacea may help relieve your symptoms and improve your quality of life. Read on to learn more about your treatment options. Topical treatments Topical treatments are applied directly to your skin. For example, they may be sold as a gel, cream, or lotion. Several topical treatments are available to manage symptoms of rosacea. Depending on your specific symptoms, your doctor might recommend one or more of the following: ivermectin azelaic acid brimonidine dapsone metronidazole oxymetazoline hydrochloride sulfacetamide/sulphur Depending on your condition and the topical treatments that you use, it might take several weeks to notice improvement in your symptoms. Topical treatments sometimes cause side effects, such as skin dryness or irritation. These side effects tend to be mild. Your doctor can help you learn more about the potential benefits and risks of different topical treatments. Eye drops Ocular rosacea is a type of rosacea that affects the eyes. It can cause eye dryness and other symptoms. If you have ocular rosacea, your doctor might encourage you to use 'artificial tears' to relieve eye dryness. Artificial tears are lubricating eye drops that you can buy over the counter, without a prescription. In severe cases, your doctor might prescribe cyclosporin drops. Cyclosporin is a type of immunosuppressant medication that may improve your eyes' production of natural tears. Cyclosporin drops may cause a temporary burning sensation or other side effects. Talk to your doctor to learn more about the potential benefits and risks of using them. Oral medications In more advanced cases, your doctor might prescribe one or more oral medications to treat rosacea. To treat flushing or redness, your doctor might prescribe an oral medication that constricts blood vessels, such as: mirtazapine propranolol carvedilol If you have a lot of pimples or pustules caused by rosacea, your doctor might prescribe an oral antibiotic, such as: minocycline doxycycline erythromycin clarithromycin clindamycin In some cases, they might prescribe a medication known as oral isotretinoin. However, this medication can cause serious side effects, including birth defects. In general, your risk of side effects tends to be higher when you use oral medications rather than topical treatments alone to manage rosacea. That's why your doctor will likely encourage you to try topical treatments before they prescribe oral medications for rosacea. Light therapy Light therapy is also known as phototherapy. It involves the use of lasers or other light-emitting tools to treat skin conditions. Laser therapy and intense pulsed light therapy may help reduce redness caused by rosacea. They may also help reduce the appearance of dilated blood vessels, which are sometimes known as spider veins. Avoiding triggers If you have rosacea, certain triggers might cause your symptoms to get worse. For example, potential triggers include: stress sunlight exposure hot, cold, or windy weather conditions certain types of foods, such as spicy foods and those containing the compound cinnamaldehyde (including tomatoes and citrus fruits) certain types of drinks, such as alcoholic or hot beverages certain types of skin care products Pay close attention to your symptoms and any triggers that might make them worse. After identifying a potential trigger, try to limit or avoid it. For example, to limit sunlight exposure, aim to stay indoors or in shaded areas during the sunniest parts of the day. Wear sunscreen and a wide-brimmed hat when you're outside. It's also important to develop a gentle skin care routine. Use a mild facial cleanser and moisturizer to help reduce irritation and minimize symptoms. Effects of medications and supplements Some medications and supplements may make your rosacea symptoms worse. These include: calcium channel blockers niacin (vitamin B3) supplements nicotinic acid nitrates sildenafil If you take any of these medications or supplements and you think they might be making your rosacea symptoms worse, let your doctor know. In some cases, your doctor might recommend changes to your medication or supplement regimen. In other cases, they might advise you to continue with your treatment plan as usual. Your doctor can help you understand the potential benefits and risks of making a change to any medications or supplements you take.

Why is My Forehead Breaking Out? Plus Tips for Treatment and Prevention
Why is My Forehead Breaking Out? Plus Tips for Treatment and Prevention

Health Line

time02-07-2025

  • Health
  • Health Line

Why is My Forehead Breaking Out? Plus Tips for Treatment and Prevention

Forehead acne is typically caused by hormones or irritation from products applied to your skin or hair. Some health conditions, like rosacea, may cause similar symptoms. Forehead acne often looks like solid red bumps, called papules. You might also see bumps with a collection of pus at the top. These are called pustules. No matter where you spot acne, it's important to treat it properly. You can use over-the-counter (OTC) or prescription medication to help the pimples clear up more quickly. This article reviews common causes of forehead acne and what you can do to treat and prevent it. What causes acne to form on your forehead? No matter where acne forms on your face, the cause is the same. Oil called sebum normally lubricates and protects your skin. Sebum is produced in tiny oil glands called sebaceous glands. Oil gets to the surface of your skin through small holes called pores. Sometimes, pores get clogged with dirt, excess oil, and dead skin cells. Bacteria grow inside, and inflammation occurs, creating swollen bumps, which are pimples. A number of factors can increase oil production and make you more likely to get acne. Read on to learn about the most common causes. Puberty hormones People of all ages can get acne, but it is more common in teens. This is most likely due to puberty hormones. During puberty, a surge in hormone levels increases oil production, which can lead to pimples. The forehead is one of the most common locations for these early breakouts. Stress hormones While stress doesn't directly cause acne breakouts, stress can trigger the release of cortisol, a stress hormone. Cortisol stimulates sebaceous glands to make more oil, which can lead to clogged pores. Hair and hair products Your hair can also be the source of forehead acne. If you don't wash your hair often enough or if you have oily hair, the oil can deposit on your forehead and clog pores there. Breakouts might also be due to the hair products you use. Hair styling and straightening products are notorious for causing acne. These include: pomades oils gels waxes These products often contain ingredients like cocoa butter or coconut oil. They can leave your skin extra oily. Acne caused by hair products is called pomade acne. Clothing or makeup irritation Irritation from clothing or the chemicals in makeup can also cause forehead acne, especially if your skin is sensitive. You may get a breakout after you use a new makeup brand or if you wear a hat or headband that irritates your skin. Touching your face a lot can also lead to acne. Your fingers deposit oil and bacteria onto your skin and into your pores. Genetics Your chances of getting forehead acne can increase if a close relative, such as your father or mother, has a history of acne. Genetics can also determine how effective your body's immune system is at warding off bacteria that promote acne. Hygiene habits Not washing your face every night can cause a buildup of oil, dirt, and dead skin cells. If you use makeup, it's also important to remove it each night. Infrequent face washing can lead to clogged pores. Certain medications Certain medications may cause acne as a side effect. These include: Oral corticosteroids Contraceptives, such as: medroxyprogesterone injection (Depo-Provera) implanted (Jadelle or Implanon) intrauterine progesterone (e.g., Mirena) oral contraceptives Testosterone Anabolic steroids, such as danazol, stanozolol, and nandrolone What are the best home treatments for forehead acne? To get rid of pimples on your forehead, start with good skin care. Wash your face twice a day with a gentle cleanser. This will remove excess oil from your skin. If that doesn't work, try an OTC acne cream that contains ingredients like benzoyl peroxide or salicylic acid. Natural remedies Some natural remedies may help treat mild acne. These include: aloe vera azelaic acid green tea extract tea tree oil zinc What are the best medical treatments for acne? For more severe acne, see a dermatologist. The Healthline FindCare tool can provide options in your area if you don't already have a dermatologist. A dermatologist can recommend prescription-strength acne treatment, such as: antibiotics benzoyl peroxide formulation retinoids birth control pills (for women) anti-androgen (hormone blocking) agent Antibiotics and retinoids come in a cream. You can take them in pill form, too. Your dermatologist may also recommend other treatments to clear up acne, such as lasers and chemical peels. Larger pimples may need to be drained. Is it safe to pop a pimple on your forehead? You never want to pop a pimple on your forehead — or anywhere else on your face or body. Picking at acne introduces dirt from your fingers into your skin, which can lead to an infection. When you pop a pimple, it'll take longer to heal. Popping can also leave a permanent scar. What other conditions cause forehead breakouts? These other conditions can also cause bumps to form on your forehead: Boils are red, painful lumps that grow out of infected hair follicles. Cellulitis is a skin infection that forms around a cut or scrape. Contact dermatitis is a skin reaction to products you use or touch, such as laundry detergent or clothing. Folliculitis is an infection of the hair follicle. Ringworm is a skin infection caused by fungi. Rosacea is a skin condition that causes redness and pimples on the face. What can you do to prevent forehead breakouts? Try these tips to prevent acne on your forehead and other parts of your face: Wash your face with a gentle cleanser twice a day. Rinse with warm water and gently pat dry. Don't scrub. Rubbing can make acne worse. Wash your hair often. If it's greasy, use a shampoo labeled for oily hair. Avoid using oils or pomade products on your hair. If you have to use them, wipe off your forehead afterward with a damp washcloth. Cut your bangs, or use a hair tie to pull them up and away from your skin. Bangs can cause acne breakouts on your forehead, especially if your hair is oily. Avoid wearing headbands or hats with brims that touch your forehead. Keep your hands away from your skin. Every time you touch your face, you introduce bacteria that can get into your pores. If you do have to touch your forehead, wash your hands first. Use makeup, cleansers, and other products labeled 'noncomedogenic.' This means they won't clog your pores and cause acne. Don't use products that can irritate the skin, like cleansers that contain alcohol.

The Best Moisturizer for Rosacea Soothes Flush and Restores Your Skin Barrier
The Best Moisturizer for Rosacea Soothes Flush and Restores Your Skin Barrier

Vogue

time13-06-2025

  • Health
  • Vogue

The Best Moisturizer for Rosacea Soothes Flush and Restores Your Skin Barrier

If you're searching for the best moisturizer for rosacea, I can relate—those red, rosy cheeks (and not the kind from blush) can be frustrating. While I can't always stop the flare-ups, a great cream can soothe the irritation and help repair your skin barrier. 'Rosacea is a skin condition associated with redness, dryness and irritation—and anyone with rosacea should look for a moisturizer with calming ingredients to reduce inflammation,' board-certified dermatologist Dr. Dara Spearman tells Vogue, noting that moisturizers act as a protective barrier and should soothe while adding much needed hydration. I'm fairly new to the rosacea club myself and didn't receive a diagnosis until just a year ago. After months of dealing with flare-ups on my cheeks, I went through a frustrating cycle of thinking it was just acne, applying various pimple creams, and finding no relief. Eventually, I visited my new dermatologist, who took one look at my cheeks and spoted those annoying red speckles as a case of rosacea. Vogue's Favorite Moisturizer for Rosacea In This Story Step one to soothing rosacea is removing any irritants from you skin-care regimen that could be making your flareups worse. Dr. Spearman advises avoiding drying and irritating ingredients all together—with alcohol, fragrances, and harsh exfoliants, being at the top of a non-negotiable no-no's list. Ahead, a look at the best moisturizers to consider to gently soothe and restore your rosacea prone skin—with picks from expert dermatologists. Best Color-Correcting: Skinceuticals Redness Neutralizer Why We Love It: Whether you have dry, sensitive, combination, or mature skin—New York-based, board-certified dermatologist, Dr. Noah Gratch says this SkinCeuticals pick is an excellent choice for those dealing with rosacea on top of their usual skin type. 'The formula features skin soothing ingredients like eperua falcata bark extract, palmitoyl tripeptide-8 and bisabolol, as well as hydrating glycerin—all of which help to soothe irritation immediately,' he explains, adding that it color corrects while treating an inflamed complexion. Whether you have dry, sensitive, combination, or mature skin—New York-based, board-certified dermatologist, Dr. Noah Gratch says this SkinCeuticals pick is an excellent choice for those dealing with rosacea on top of their usual skin type. 'The formula features skin soothing ingredients like eperua falcata bark extract, palmitoyl tripeptide-8 and bisabolol, as well as hydrating glycerin—all of which help to soothe irritation immediately,' he explains, adding that it color corrects while treating an inflamed complexion. Key Ingredients: Palmitoyl tripeptide-8, eperua falcata bark extract, bisabolol, zinc gluconate, glycerin, shea butter Palmitoyl tripeptide-8, eperua falcata bark extract, bisabolol, zinc gluconate, glycerin, shea butter Size: 1.67 oz Best Rich Moisturizer: Clinique Redness Solutions Daily Relief Face Cream Why We Love It : For those with super dry, irritated skin, Dr. Gratch cosigns this face cream—this formula gets it's rich texture from shea butter (though, keep in mind shea butter is a no-no for acne-prone skin types). The true star ingredient of this formula is lactobacillus—a probiotic extract that helps repair the microbiome to rapidly calm redness and irritation. Meanwhile, bisabolol provides additional soothing benefits as well as protection from free radical damage. 'Clinique's hydrates without feeling heavy or greasy, which is key for comfortability. The formula is also fragrance-free, making it a good choice for sensitive skin,' says Dr. Gratch. : For those with super dry, irritated skin, Dr. Gratch cosigns this face cream—this formula gets it's rich texture from shea butter (though, keep in mind shea butter is a no-no for acne-prone skin types). The true star ingredient of this formula is lactobacillus—a probiotic extract that helps repair the microbiome to rapidly calm redness and irritation. Meanwhile, bisabolol provides additional soothing benefits as well as protection from free radical damage. 'Clinique's hydrates without feeling heavy or greasy, which is key for comfortability. The formula is also fragrance-free, making it a good choice for sensitive skin,' says Dr. Gratch. Key Ingredients : Shea butter, lactobacillus extract, bisabolol : Shea butter, lactobacillus extract, bisabolol Size: 1.7 oz Best Viral: Cicapair Intensive Soothing Relief Cream Dr. Jart+ Cicapair Intensive Soothing Repair Cream $54 SEPHORA Why we love it: This TikTok Viral K-beauty is Dr. Blair Murphy-Rose's go-to pick for soothing and repairing inflamed skin. 'Its namesake ingredient cica, or centella asiatica, is rich in fatty acids, vitamins, and amino acids,' she previously told Vogue, noting it's also a great choice for mature skin. 'Centella asiatica is awesome for calming redness and helping your skin heal—this is a popular choice for patients with rosacea,' adds Dr. Gratch. This TikTok Viral K-beauty is Dr. Blair Murphy-Rose's go-to pick for soothing and repairing inflamed skin. 'Its namesake ingredient cica, or centella asiatica, is rich in fatty acids, vitamins, and amino acids,' she previously told Vogue, noting it's also a great choice for mature skin. 'Centella asiatica is awesome for calming redness and helping your skin heal—this is a popular choice for patients with rosacea,' adds Dr. Gratch. Key ingredients : Cica complex, allantoin : Cica complex, allantoin Size: 1.69 oz Best French Pharmacy: La Roche Posay Toleriane Double Repair Face Moisturizer La Roche-Posay Toleraine Double Repair Face Moisturizer $24 AMAZON Why We Love It : This La Roche-Posay moisturizer is beloved by dermatologists for a good reason: it does exactly what it promises. The lightweight, oil-free cream sinks in effortlessly, instantly soothing skin with a refreshing dose of prebiotic thermal water and barrier-repairing ceramides. Niacinamide adds a layer of calm (redness, be gone), while glycerin locks in hydration for the long haul. Fragrance-free and non-comedogenic, it plays well with everything from exfoliants to actives, making it a true staple for even the most sensitive complexions. : This La Roche-Posay moisturizer is beloved by dermatologists for a good reason: it does exactly what it promises. The lightweight, oil-free cream sinks in effortlessly, instantly soothing skin with a refreshing dose of prebiotic thermal water and barrier-repairing ceramides. Niacinamide adds a layer of calm (redness, be gone), while glycerin locks in hydration for the long haul. Fragrance-free and non-comedogenic, it plays well with everything from exfoliants to actives, making it a true staple for even the most sensitive complexions. Key Ingredients: Ceramide-3, niacinamide, glycerin, prebiotic thermal water Ceramide-3, niacinamide, glycerin, prebiotic thermal water Size: 3.38 fl oz Best With Niacinamide: EltaMD Barrier Renewal Complex EltaMD Barrier Renewal Complex $62 AMAZON Why We Love It: Formulated with a blend of ceramides, hyaluronic acid, and squalane, this moisturizer provides deep hydration and strengthens the skin's natural defenses. Its lightweight, non-greasy texture makes it suitable for daily use, even under makeup. 'This pick from EltaMd has niacinamide to reduce redness, and includes antioxidants and barrier support— it's an all around a solid choice for rosacea,' says Dr. Gratch. Formulated with a blend of ceramides, hyaluronic acid, and squalane, this moisturizer provides deep hydration and strengthens the skin's natural defenses. Its lightweight, non-greasy texture makes it suitable for daily use, even under makeup. 'This pick from EltaMd has niacinamide to reduce redness, and includes antioxidants and barrier support— it's an all around a solid choice for rosacea,' says Dr. Gratch. Key Ingredients: Ceramide blend, hyaluronic acid, squalane, niacinamide, vitamin E (tocopherol) Ceramide blend, hyaluronic acid, squalane, niacinamide, vitamin E (tocopherol) Size: 1.7 oz Best With Colloidal Oatmeal: Aveeno Calm + Restore Oat Gel Moisturizer Aveeno Calm + Restore Oat Gel Moisturizer $27 AMAZON Why We Love It: Looking for a solid drugstore gel moisturizer? 'Aveeno's star ingredient used in this formula is colloidal oatmeal, a classic calming ingredient. The gel texture is lightweight but still soothing and hydrating, perfect if your skin feels irritated,' says Dr. Gratch. This hypoallergenic formula is free from parabens, alcohols, dyes, and phthalates, making it ideal for those with reactive skin. Looking for a solid drugstore gel moisturizer? 'Aveeno's star ingredient used in this formula is colloidal oatmeal, a classic calming ingredient. The gel texture is lightweight but still soothing and hydrating, perfect if your skin feels irritated,' says Dr. Gratch. This hypoallergenic formula is free from parabens, alcohols, dyes, and phthalates, making it ideal for those with reactive skin. Key Ingredients: Prebiotic oat, feverfew Prebiotic oat, feverfew Size: 1.7 oz Best With Peptides: Skinfix Triple Lipid-Peptide Cream Skinfix Barrier+ Moisturizing Triple Lipid-Peptide Cream $54 AMAZON Why We Love It : 'This hydrating face cream works to brighten, firm, plump and moisturize using key ingredients such as lipids, peptides, hyaluronic acid, and shea butter,' Dr. Garshick. previously told Vogue. Not to mention, it's this beauty writer's go-to moisturizer during a particularly angry rosacea flair up, when in need of extra TLC for irritated skin. Best of all, it's a super hygienic choice, given the pump cap (i.e., no digging your fingers into the jar to scoop product!). : 'This hydrating face cream works to brighten, firm, plump and moisturize using key ingredients such as lipids, peptides, hyaluronic acid, and shea butter,' Dr. Garshick. previously told Vogue. Not to mention, it's this beauty writer's go-to moisturizer during a particularly angry rosacea flair up, when in need of extra TLC for irritated skin. Best of all, it's a super hygienic choice, given the pump cap (i.e., no digging your fingers into the jar to scoop product!). Key ingredients : Triple lipid complex, nutri-peptide blend, glycerin : Triple lipid complex, nutri-peptide blend, glycerin Size: 1.7 oz Best for Reactive Skin: Etude House SoonJung 2x Barrier Intensive Cream Etude SoonJung 2x Barrier Intensive Cream $17 AMAZON Why We Love It : Made for very sensitive skin types (we're looking at you too, eczema girlies!), this pick is formulated without mineral oil, fragrance, and other common allergens. For added assurance, the formula is dermatologist tested to ensure that it won't irritate reactive skin or lead to hypersensitivity. A combination of panthenol (which boosts skin's ability to retain moisture) and madecassoside (from which redness-reducing cica is derived) power its soothing benefits. : Made for very sensitive skin types (we're looking at you too, eczema girlies!), this pick is formulated without mineral oil, fragrance, and other common allergens. For added assurance, the formula is dermatologist tested to ensure that it won't irritate reactive skin or lead to hypersensitivity. A combination of panthenol (which boosts skin's ability to retain moisture) and madecassoside (from which redness-reducing cica is derived) power its soothing benefits. Key Ingredients : Panthenol, madecassoside, green tea extract : Panthenol, madecassoside, green tea extract Size: 2.02 fl. oz. Best for Healing: Tower 28 SOS Barrie Recovery Cream Tower 28 SOS Recovery Cream $24 AMAZON Why We Love It: You've probably heard of Tower 28's popular SOS Daily Rescue Facial Spray. Well, now, there's a moisturizer formula to complement it. This rich formula is filled with skin-soothing ingredients like oat extract and ceramides, which help calm irritation and strengthen your skin's natural defenses. It's ideal for post-treatment care, or everyday hydration. The formula instantly soothes redness and discomfort while locking in moisture throughout the day. It's lightweight enough to wear under makeup but nourishing enough to use overnight. You've probably heard of Tower 28's popular SOS Daily Rescue Facial Spray. Well, now, there's a moisturizer formula to complement it. This rich formula is filled with skin-soothing ingredients like oat extract and ceramides, which help calm irritation and strengthen your skin's natural defenses. It's ideal for post-treatment care, or everyday hydration. The formula instantly soothes redness and discomfort while locking in moisture throughout the day. It's lightweight enough to wear under makeup but nourishing enough to use overnight. Key Ingredients: Oat extract, ceramides, squalane, shea butter, vitamin E Oat extract, ceramides, squalane, shea butter, vitamin E Size: 1.7 oz (50 mL) Best Water Cream: The Inkey List Omega Water Cream The Inkey List Omega Water Cream $12 AMAZON Why We Love It: Another affordable, gel-cream formula, this Inkey List pick transforms into a water-like texture upon contact with the skin, providing a lightweight veil of moisture. Formulated with a blend of omega fatty acids, niacinamide, and glycerin, it helps strengthen the skin barrier, lock in moisture, and promote a smooth, balanced complexion Another affordable, gel-cream formula, this Inkey List pick transforms into a water-like texture upon contact with the skin, providing a lightweight veil of moisture. Formulated with a blend of omega fatty acids, niacinamide, and glycerin, it helps strengthen the skin barrier, lock in moisture, and promote a smooth, balanced complexion Key Ingredients: Omega fatty acids,niacinamide, glycerin Omega fatty acids,niacinamide, glycerin Size: 1.7 oz Best Classic: Vanicream Moisturizing Skin Cream Vanicream Daily Facial Moisturizer $14 AMAZON Why We Love It: Vanicream is another classic skin-care choice in any dermatologist's office, thanks to its no-nonsense formulation. This fragrance-free formula is specifically for sensitive skin types. Its lightweight, non-greasy texture provides long-lasting hydration with a blend of hyaluronic acid and five essential ceramides, to restore and maintain the skin's natural moisture barrier. 'This is a great simple option. It's free from dyes and irritants—just pure, effective moisturizing,' says Dr. Gratch. Vanicream is another classic skin-care choice in any dermatologist's office, thanks to its no-nonsense formulation. This fragrance-free formula is specifically for sensitive skin types. Its lightweight, non-greasy texture provides long-lasting hydration with a blend of hyaluronic acid and five essential ceramides, to restore and maintain the skin's natural moisture barrier. 'This is a great simple option. It's free from dyes and irritants—just pure, effective moisturizing,' says Dr. Gratch. Key Ingredients: Hyaluronic acid, ceramides (EOP, NG, NP, AS, AP), squalane, glycerin Hyaluronic acid, ceramides (EOP, NG, NP, AS, AP), squalane, glycerin Size: 3 fl oz Best Night Cream: Cetaphil Redness Relieving Night Moisturizer for Face Why We Love It: Another tried-and-true choice for anyone battling skin concerns—Cetaphil's night cream delivers no fluff, just high performing ingredients. It features anti-inflammatory licorice extract and nourishing allantoid, plus caffeine to supercharge skin healing overnight. While beverages containing the substance can trigger rosacea flare-ups, topical caffeine helps instantly fade redness for a more even-toned complexion. Another tried-and-true choice for anyone battling skin concerns—Cetaphil's night cream delivers no fluff, just high performing ingredients. It features anti-inflammatory licorice extract and nourishing allantoid, plus caffeine to supercharge skin healing overnight. While beverages containing the substance can trigger rosacea flare-ups, topical caffeine helps instantly fade redness for a more even-toned complexion. Key Ingredients: Licorice extract, allantoin, caffeine Licorice extract, allantoin, caffeine Size: 8 fl oz Best With Azelaic: The Ordinary Azelaic Acid 10% Suspension Brightening Cream The Ordinary Azelaic Acid 10% Suspension Brightening Cream $12 AMAZON Why We Love It: Azelaic acid, a dicarboxylic acid derived from yeast, is often prescribed as a topical treatment to address acne-like rosacea at a concentration of 15% or 20%. This budget-friendly, over-the-counter pick features the active at a potent 10% concentration in a silky, primer-like base. 'In addition to gently exfoliating away rough texture and decongesting pores, azelaic acid has antibacterial and anti-inflammatory properties that make it great for rosacea,' says board-certified dermatologist Dr. Morgan Rabach. Azelaic acid, a dicarboxylic acid derived from yeast, is often prescribed as a topical treatment to address acne-like rosacea at a concentration of 15% or 20%. This budget-friendly, over-the-counter pick features the active at a potent 10% concentration in a silky, primer-like base. 'In addition to gently exfoliating away rough texture and decongesting pores, azelaic acid has antibacterial and anti-inflammatory properties that make it great for rosacea,' says board-certified dermatologist Dr. Morgan Rabach. Key Ingredients: Azelaic acid, tocopherol, dimethicone Azelaic acid, tocopherol, dimethicone Size: 1 oz Best Brightening: Eadem Cloud Cushion Airy Brightening Moizturizer EADEM Cloud Cushion Airy Brightening Moisturizer $58 AMAZON Why We Love It: Eadem's moisturizer features a lightweight texture rich in powerful ingredients. Infused with ceramides, this formula strengthens the skin and retains moisture in essential areas. Additionally, peptides and niacinamide help protect against dark spots while brightening the skin and refining pores. Plus, this formula has been dermatologist-tested. Eadem's moisturizer features a lightweight texture rich in powerful ingredients. Infused with ceramides, this formula strengthens the skin and retains moisture in essential areas. Additionally, peptides and niacinamide help protect against dark spots while brightening the skin and refining pores. Plus, this formula has been dermatologist-tested. Key Ingredients: Snow mushroom extract, peptides, ceramides, squalane Snow mushroom extract, peptides, ceramides, squalane Size: 1.7 oz Best Whipped: Youth To The People Superfood Air Whip Moisture Cream Why We Love It: If you're a fan of clean beauty, you'll love Youth To The People's gel cream, which is enriched with leafy greens such as kale and spinach, and bolstered by a moisturizing dose of hyaluronic acid—all of which boast anti-inflammatory properties. Think of it as a green juice smoothie, but for your face—it's both refreshing and packed with antioxidants from superfood ingredients. If you're a fan of clean beauty, you'll love Youth To The People's gel cream, which is enriched with leafy greens such as kale and spinach, and bolstered by a moisturizing dose of hyaluronic acid—all of which boast anti-inflammatory properties. Think of it as a green juice smoothie, but for your face—it's both refreshing and packed with antioxidants from superfood ingredients. Key Ingredients: Sunflower seed oil, glycerin, vitamin B5, vitamin E, vitamin C, kale leaf extract, green tea leaf extract Sunflower seed oil, glycerin, vitamin B5, vitamin E, vitamin C, kale leaf extract, green tea leaf extract Size: 2 oz Best with Honey: Farmacy Honey Halo Ultra-Hydrating Ceramide Moisturizer Farmacy Honey Halo Ultra-Hydrating Ceramide Moisturizer $25 Shop Now Why We Love It : Farmacy's honey-infused moisturizer offers clean, cruelty-free nourishment to lock in hydration for glowing skin. Another TikTok-darling on our list, this is exceptionally hydrating without weighing skin down (and almost 4,000 glowing Amazon reviews back that claim). With consistent use, skin appears brighter and fine lines look smoother. What's more, Honey Halo is gentle enough for day or night. : Farmacy's honey-infused moisturizer offers clean, cruelty-free nourishment to lock in hydration for glowing skin. Another TikTok-darling on our list, this is exceptionally hydrating without weighing skin down (and almost 4,000 glowing Amazon reviews back that claim). With consistent use, skin appears brighter and fine lines look smoother. What's more, Honey Halo is gentle enough for day or night. Key Ingredients : Ceramide NP, buckwheat honey, royal jelly extract, fig fruit extract, osmolytes, and panthenol : Ceramide NP, buckwheat honey, royal jelly extract, fig fruit extract, osmolytes, and panthenol Available size : 0.3 oz, 0.5 oz, 0.84 oz, 1.7 oz, 3.4 oz : 0.3 oz, 0.5 oz, 0.84 oz, 1.7 oz, 3.4 oz Type : Cream : Cream Fragrance: Yes, natural fragrance Everything You Need To Know

Gut Health in Rosacea: Diet, Probiotics, and the Microbiome
Gut Health in Rosacea: Diet, Probiotics, and the Microbiome

Medscape

time29-05-2025

  • Health
  • Medscape

Gut Health in Rosacea: Diet, Probiotics, and the Microbiome

Growing evidence suggested that the skin and gut may be more closely linked than once thought — especially in chronic inflammatory conditions like rosacea. In a comprehensive review recently published in Biomolecules , Marco Manfredini, MD, from the Department of Dermatology at the University of Modena and Reggio Emilia, Modena, Italy, and colleagues explored the evolving science around how diet, gut microbiota, and probiotics may influence rosacea pathogenesis and symptom severity. While more clinical studies are needed, the review highlighted new pathways linking gastrointestinal dysbiosis to cutaneous inflammation. The authors proposed that specific dietary modifications and the use of probiotics could support traditional treatment approaches for certain patients. Pathogenesis of Rosacea: A Multifactorial Inflammatory Process Rosacea arises from a complex interplay of multiple contributing factors. 'The pathogenesis of rosacea continues to be a subject of investigation,' the authors wrote, involving 'dysregulation of the innate immune response and neuropeptide activity, microbial involvement, environmental factors, dietary triggers, and skin barrier dysfunction.' Central to these mechanisms is the innate immune system. In rosacea, elevated levels of kallikrein-5 trigger excessive processing of antimicrobial peptides into proinflammatory fragments such as LL-37. These fragments promote oxidative stress, cytokine release, and blood vessel changes, contributing to the inflammation and vascular symptoms seen in the disease, according to the authors. Neurovascular dysregulation is also a hallmark of the disease. The authors noted, 'activation of TRPV1 [Transient Receptor Potential Cation Channel Subfamily V Member 1] and related channels by environmental triggers like heat and UV [ultraviolet] radiation exacerbate flushing and erythema by promoting vasodilation and neurogenic inflammation.' These channels are hypersensitive in patients with rosacea, contributing to enhanced symptom severity. While the skin microbiome — particularly Demodex folliculorum and its associated Bacillus oleronius — has long been considered a contributing factor, recent attention has turned to the gut. 'Emerging evidence suggests that while microorganisms may not be central causative factors… alterations in the skin microbiome across multiple rosacea subtypes may act as trigger factors or potentiate inflammation,' the review authors wrote. 'Gastrointestinal dysbiosis, including conditions such as Helicobacter pylori infection and small intestinal bacterial overgrowth (SIBO),' they noted, 'has been hypothesized as a potential contributor to rosacea development.' Gut Dysbiosis and the Skin: The Available Evidence The concept of a gut–skin axis describes the bidirectional relationship between intestinal microbiota and skin inflammation. In rosacea, this relationship is supported by associations with conditions like SIBO, H pylori infection, and inflammatory bowel diseases, as highlighted in the Manfredini review. Asked to comment on this emerging topic, Rajani Katta, MD, clinical professor of dermatology at the McGovern Medical School, University of Texas, Houston, noted, 'We have strong evidence linking gut dysbiosis to rosacea, but it is important to note that this applies only to certain patients. In other words, only a subset of patients with rosacea seems to have gut dysbiosis, and in those patients, there appears to be a link.' Rajani Katta, MD Katta added that the most compelling mechanisms relate to inflammation. 'Patients with SIBO may have higher levels of inflammatory mediators, such as tumor necrosis factor alpha. In other studies, gut dysbiosis can lead to the activation of specific inflammatory pathways like the kallikrein-kinin pathway. Activation of these pathways has multiple downstream effects, which may ultimately increase neurogenic inflammation in the skin.' The review by Manfredini and colleagues supported these theories, citing studies that show improvement in rosacea symptoms following SIBO eradication, although the benefit of H pylori treatment is less clear. 'The association between Helicobacter pylori infection and rosacea remains complex and influenced by several confounding factors,' the authors wrote. 'The antibiotic treatment required for H pylori eradication represents an important confounding factor.' The authors caution that without large-scale prospective studies examining the gut microbiome before and after intervention, firm conclusions about causality remain elusive. Dietary Triggers: What the Evidence Supports Dietary factors may influence rosacea by promoting vasodilation, activating sensory receptors, or altering the gut microbiome. Yet, data on specific triggers remain mixed, according to the authors. Asked to comment on dietary triggers in rosacea, Lauren Kole, MD, associate professor of dermatology at the University of Alabama at Birmingham, said that 'the best data for dietary triggers for rosacea are for alcohol and hot beverages. Alcohol may induce peripheral vasodilation, promote inflammation, modulate the immune system, and may trigger histamine release. Hot beverages may cause direct vasodilation and trigger other pathways that lead to flushing, stinging, and sensitive skin.' Katta also noted that alcohol and hot beverages 'are common triggers, likely because they lead to vasodilation, which causes flushing.' She also highlighted spicy foods as a culprit. 'Foods that contain capsaicin may result in vasodilation and thus flare rosacea, so avoiding spicy foods may be helpful.' Another category included foods that contain cinnamaldehyde — a compound found in cinnamon, tomatoes, and citrus —which may trigger flushing in sensitive individuals, according to Katta. Katta recommended a practical approach for patients. 'For most patients, a 6-week trial of eliminating the most commonly reported food triggers in rosacea is a good first step… I tell patients that it can take 6 weeks of avoiding these foods to see if it will be helpful, and I recommend a food diary.' Interestingly, certain foods may offer benefits. Dairy products have been associated with reduced rosacea severity in some populations, potentially because of their anti-inflammatory effects. High-fiber diets may support gut microbial diversity and caffeine — despite its reputation — has been inversely associated with rosacea in large observational studies, cited in the Manfredini review. Probiotics: Potential but Preliminary Probiotics are another area of growing interest. These live microorganisms may influence rosacea by rebalancing the gut microbiome, reducing inflammatory cytokine production, and enhancing skin barrier function, according to the authors. 'Dietary probiotics may help normalize skin dysbiosis in rosacea and may limit substance P-induced skin inflammation,' said Kole. She referenced a study that found improved skin barrier function and reduced sensitivity with oral probiotic use alongside doxycycline therapy. Katta said that she has not used probiotics for rosacea in her practice. 'Preliminary results appear intriguing, but there are still many questions about the optimal strain of probiotics as well as dose and duration,' she told Medscape Medical News . She added that the current evidence is 'too preliminary to recommend specific strains or delivery routes, although some have shown benefit,' referencing studies on strains of Bifidobacterium , Lactobacillus , and Escherichia coli Nissle included in the Manfredini review. Topical formulations are also being explored with promising results, and a product containing Vitreoscilla filiformis has shown reductions in facial erythema and Demodex density while improving transepidermal water loss, according to the review's authors. However, mirroring Katta's sentiment, the authors concluded that 'despite promising results, the evidence supporting the use of probiotics in the treatment of rosacea remains relatively limited. Further clinical trials are necessary to evaluate and compare the effectiveness of various probiotic strains and different methods of delivery, such as oral ingestion and topical use.' Looking Ahead: Clinical Considerations and Research Needs While the current research is promising, more rigorous studies are needed. 'One of the research areas that I'd love to see more of,' Katta said, 'is measuring rates of gut dysbiosis in patients with rosacea, with prospective studies examining gut microbiome composition before and after treatment, and how that correlates to rosacea severity.' For now, clinicians may consider an individualized approach, she said, and asking about gastrointestinal symptoms, evaluating for common dietary triggers, and discussing a food elimination trial can be helpful strategies. Although formal probiotic guidelines for rosacea are lacking, some patients may benefit from a monitored trial of supplementation — particularly if they also have gut-related complaints, she added. 'There are many gaps in our understanding of the gut–skin axis,' Katta emphasized. 'But it's an exciting area of dermatologic research.'

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