Latest news with #GABA
Daily Mirror
6 hours ago
- Health
- Daily Mirror
40p-a-day GP-backed supplement gives 'stressed' shoppers a 'full night's sleep'
Noggin's Pause supplement is usually £29.99 for 60 capsules, but there's a way to get them cheaper Many people struggle to switch off at night, unwind, destress and achieve a good night's sleep. A study by Restorez revealed that 65% of individuals seldom wake up feeling refreshed and recharged, often seeking methods to improve their sleep quality. It's not uncommon for individuals to hunt for hacks, tips, and tricks to facilitate easier sleep, which can become overwhelming if unsuccessful. Now, customers can purchase the supplement Pause from Noggin from £23.99, claimed to soothe the mind, promote relaxation, and foster peaceful, quality sleep. Noggin was founded by GP Dr Clara Doran and is free of fillers, additives or unnecessary ingredients. Customers can now try Pause for themselves with the premium supplement featuring a unique blend of botanicals, minerals and medicinal mushrooms, specifically selected for their clinically proven brain-supportive and nootropic properties. All components have undergone research and clinical testing, providing reassurance to those seeking relaxation that it will indeed be effective. The Pause supplement contains a variety of key ingredients chosen to support brain health and reduce stress and anxiety. These include Ashwagandha, an adaptogenic herb native to India that helps balance the body and mind, reports the Express. It's also shown to reduce cortisol levels, enhance GABA receptors, regulate serotonin, and protect the brain from oxidative damage. Other ingredients include lemon balm, l-thenanine, hop extract, rhodiola rosea, and lion's mane mushroom. For optimal results, customers are advised to take 1-2 capsules with food daily. However, those who are pregnant, breastfeeding, or on medication should consult their healthcare practitioner before use. It's also important to note that the product is not intended as a substitute for a varied diet and healthy lifestyle. Usually £29.99, the supplements can be purchased cheaper via the brand's subscribe and save service. (£23.99) If taking one per day, it would work out at 40p a day, or 80p a day if taking two. This brand isn't the only supplement on the market for stress and sleep and shoppers can try some alternatives. For example, there is the JSHealth Calm + De-Stress 60 Tablets for £15.99 from Boots which is designed to promote serenity and mental wellbeing through a combination of adaptogens, herbs and vitamins. Another option is Bach RESCUE Peaceful Night 30 Capsules for £18.25 from Holland & Barrett which is said to support a peaceful night's sleep and is vegan. Pause has received a high rating of 4.9 out of 5 stars on Noggin's website. One satisfied customer shared: "I've been taking PAUSE for 3 weeks and already feel much calmer and my sleep is so much better." Another wrote: "I've been trying PAUSE for a few weeks and seen a difference. It has helped relax me when I feel anxious and quite stressed throughout the day which then affects my sleep at night. First time in years I had a full nights sleep and improved my overall mood." Not everyone was bowled over and failed to experience all the advantages. One two-star rating read: 'I really wanted to love this product having read all the other reviews, but it didn't seem to work for me. I am back to trying to find a solution to the daily afternoon slump.' However another wrote: "I've been going through a lot of stress at home and couldn't sleep as a result. I've been taking PAUSE for a week and it has made it easier to shut my worries off when I go to bed and actually get some sleep. Less stressed and anxious when I wake up which is such a relief." For those wanting to relax, de-stress and enjoy a proper night's rest, Pause from Noggin might be a brilliant supplement to consider.
New York Post
a day ago
- Health
- New York Post
The ‘very potent' supplement once given to Soviet cosmonauts can curb anxiety
Houston, we have a chill pill. Back in the 1960s, Soviet scientists developed a sweet little supplement that they stocked in the space kits of cosmonauts — the Russian version of an astronaut — to keep them cool under pressure. Still a popular over-the-counter option in Russia today, the drug promises to curb anxiety, cure insomnia, manage alcohol withdrawal and PTSD and promote clear thinking. Advertisement 3 Back in the 1960s, Soviet scientists developed a sweet little supplement that they stocked in the space kits of cosmonauts — the Russian version of an astronaut — to keep them cool under pressure. Gamma-Keystone via Getty Images It can even give you a bit of a high — but experts are warning that phenibut can also be a Red Scare in disguise. Utah recently classified it as a Schedule I controlled substance, placing it among the 'most dangerous drugs with no accepted medical use.' Phenibut's soothing properties come from its ability to mimic GABA — the neurotransmitter that mellows out brain activity — which makes it not dissimilar to benzodiazepines like Xanax and Valium. Advertisement Writer Delynn Willis started taking phenibut, sold under the brand names Anvifen, Fenibut and Noofen, precisely because she wanted to avoid the potentially addictive properties of benzos. A friend told her the Russian drug was dependence-free. 3 Phenibut's soothing properties come from its ability to mimic GABA — the neurotransmitter that mellows out brain activity — which makes it not dissimilar to benzodiazepines like Xanax and Valium. terovesalainen – Advertisement However, things quickly went south. 'After I had been using it for a few weeks, I started to notice I needed higher and higher doses to get the same effect,' she told Discover Magazine. When she tried to wean herself off the drug, the withdrawal symptoms were out of this world. Advertisement 'My anxiety skyrocketed, my temper shortened and I experienced dizzy spells,' she said. 'The drug has very potent psychoactive properties,' University of Michigan psychiatrist Edward Jouney told the outlet at the time. 'There's evidence it can cause addiction.' Jouney noted that it's possible that phenibut could be used as an effective treatment for anxiety under strict medical supervision. 3 While low doses — under a gram — might be safe, side effects can include vomiting, nausea, diarrhea, insomnia, depression, hallucinations, tremors and difficulty breathing. LIGHTFIELD STUDIOS – While it is technically legal in most of the US and sold online for as little as $50, buying phenibut this way is a dubious prospect. Telehealth companies aren't held to the same quality assurance standards as doctors, who can't prescribe it because it's not approved by the Food and Drug Administration for medical use. Advertisement Poison control centers have been flooded with phenibut-related calls since 2015, according to the Centers for Disease Control and Prevention, with reports describing agitation, heart irregularities, confusion — and even coma. In 2019, the FDA sent warning letters to three companies in the US for marketing phenibut as a 'dietary supplement.' Alabama took matters into its own hands and classified it as a Schedule II controlled substance in 2021, making it illegal. As of May, it is also illegal to possess, distribute or manufacture phenibut in Utah. Advertisement While low doses — under a gram — might be safe, side effects can include vomiting, nausea, diarrhea, insomnia, depression, hallucinations, tremors and difficulty breathing. It can be easy to become dependent, which can lead to death. 'The reported adverse events of phenibut are just scratching surface of a largely unregulated online drug market with no standards of quality assurance,' pharmacologists Janet Cheung and Jonathan Penm wrote in The Conversation. 'So for those students seeking the competitive edge, it looks like those extra marks are not worth it after all.'
Yahoo
15-07-2025
- Health
- Yahoo
O Positiv Launches Boldest Sexual Wellness Innovation Yet: URO Vaginal Moisture + Mood
A science-backed daily supplement supporting vaginal moisture, arousal, and sexual function*—designed to help close the orgasm gap and destigmatize female libido and sexual desire. LOS ANGELES, July 15, 2025 /PRNewswire/ -- O Positiv, the leading women's health brand known for disrupting stigmas around hormonal, digestive, and sexual wellness, today announced the launch of URO Vaginal Moisture + Mood, a first-of-its-kind daily supplement designed to support healthy sexual function, natural lubrication, and emotional well-being for women 18 and older. Formulated with clinically studied ingredients including GABA, KSM-66 Ashwagandha, Ginkgo Biloba, and the proprietary Passion Positiv Blend, URO Vaginal Moisture + Mood uniquely targets blood flow, stress, and mood – three essential yet often overlooked factors that impact desire and satisfaction. Unlike on-demand products or hormonal options, the supplement is designed for consistent daily use, helping women feel more connected, confident, and in control of their sexual health. "The orgasm gap isn't just a statistic – it reflects a systemic failure to center women's experiences in conversations about sex and health," said Brianna Bitton, Co-Founder of O Positiv. "We formulated URO Vaginal Moisture + Mood to directly address what's often ignored: the mental load, the dryness, the burnout. This isn't about a libido quick fix; it's about restoring connection to self and redefining what it means to feel good in your body. Change starts with conversation, and we're not interested in staying quiet." Why URO Vaginal Moisture + Mood Is Different: One of the few formulations that improves blood flow as a mechanism to support arousal* Supports natural vaginal lubrication, healthy sexual stimulation, and overall sexual satisfaction* Formulated to promote relaxation, support mood, and manage cortisol levels* Hormone-free, developed for daily use across all adult life stages Backed by the brand behind the best-selling URO Vaginal Probiotic, reinforcing O Positiv's authority in vaginal and sexual wellness "I've treated countless women facing challenges with arousal, moisture, and stress. This formula was designed with those needs in mind, to effectively support sexual health, mood, and pleasure," said Dr. Roxanne Pero, OBGYN, MD, from O Positiv's Medical Board of Directors. The product launch is supported by Wet Girl Summer, O Positiv's largest integrated campaign to date. The bold initiative includes an out-of-home campaign, a large-scale consumer activation in New York City on Saturday, August 23, and a robust social media push—all designed to spotlight the cultural taboos that continue to silence women's experiences with arousal, dryness, and intimacy. By encouraging open dialogue and unapologetic advocacy, the campaign reinforces O Positiv's belief that sexual health is health. As part of their commitment, O Positiv will also be donating to a women's health research partner, further underscoring the campaign's purpose-driven mission. "Sexual health is a vital part of overall wellness, yet it remains underserved and stigmatized," said Bobby Bitton, Co-Founder and CEO of O Positiv. "We're committed to breaking that cycle with data-backed solutions designed around what we hear directly from our community. URO Vaginal Moisture + Mood reflects our continued investment in redefining women's health—centered in confidence, comfort, and conversation." URO Vaginal Moisture + Mood is available now direct-to-consumer on and launching on Amazon in July. With science-backed ingredients, sexual health physician and OBGYN validation, and a mission to normalize conversations around female pleasure, URO Vaginal Moisture + Mood sets a new standard in sexual wellness, and signals a cultural shift long overdue. URO Vaginal Moisture + Mood was inspired by the success of MENO Vaginal Moisture, a best-seller that's helped women in menopause reclaim their sex lives. While MENO addresses moisture and libido concerns tied to estrogen loss, URO is formulated for women outside of menopause—targeting arousal, mood, and blood flow at any life stage. Sexual health is health. URO Vaginal Moisture + Mood is here to prove it. For more information, visit About O Positiv HealthO Positiv Health is a brand dedicated to prioritizing women's health by offering effective products that address historically overlooked health issues, delivering results you can feel. The brand's lineup includes solutions like the MENO Menopause Gummy, the #1 OB/GYN recommended menopause relief gummy2, as well as best-selling FLO PMS to help uncomfortable PMS symptoms and URO Vaginal Probiotic, #1 vaginal probiotic1 designed to combat vaginal odor. With more than 25,000 five-star reviews on both and O Positiv is on a mission to challenge taboos and provide solutions for vaginal, skin, digestive, menstrual, and menopausal health. To further advocate for women's health, O Positiv works closely with the American Cancer Society and is the leading sponsor of their annual 5K walk in Santa Monica, California. Shop all O Positiv products at and follow O Positiv on Instagram and TikTok at @opositiv. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Footnotes Based on aggregate internal, Amazon and retail sales, L5Y as of 5/2/2025 Aggregated review count across Shop App, Amazon, TikTok Shop, all products, as of 4/29/2025 Circana IRI Total Target Dollar Sales 12 weeks ending 3/23/25 View original content to download multimedia: SOURCE O Positiv Health Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
14-07-2025
- Health
- Yahoo
This Tasty Magnesium Supplement Turns Your Nighttime Routine Into A True Wind-Down
If your evenings feel like a fight between a racing mind and your desire for deep, uninterrupted sleep, magnesium might just be the wind-down ritual you're missing. Magnesium is an essential mineral that powers more than 600 reactions in your body, from muscle relaxation to DNA repair. But it's also a nighttime hero. It calms the nervous system, soothes tense muscles and can help you transition from 'on' all day to blissfully 'off' at night. That said, not all magnesium supplements are created equal. Pills and capsules can be hard to absorb, and some single-form magnesium options just don't deliver the whole-body support you need. That's where Mellö steps in, offering a carefully crafted powdered blend that's become a staple in thousands of bedtime routines. GET IT! Mellö's formula isn't just magnesium. It's a combination of three highly bioavailable forms — magnesium lactate gluconate, aquamin magnesium and magnesium glycinate — so your body can actually absorb and use it effectively. It also includes calming ingredients like GABA and L-theanine, plus 70+ essential trace minerals for comprehensive support. In short? It's designed to help you ease out of stress mode and into sleep mode without the crash or grogginess that often comes with traditional sleep aids. This powdered blend is also incredibly versatile. Choose from two delicious flavors or go with the unflavored 'naked' option to stir into your favorite evening tea or water without even noticing it's there. For anyone who struggles with sleep, stress or that wired-but-tired feeling, this could be the supplement that finally works with your routine instead of against it. Don't just take our word for it — customers rave about how it's transformed their nights. One wrote, 'I notice a significant difference in my quality of sleep. I really like this flavor too!' Another shared, 'It's delicious and calming in the evening, and I relax into sleep much easier when I drink it before bed.' If you're ready to make your nights smoother and your mornings brighter, mellö might be the gentle, effective ritual you've been looking for. GET IT! Get for just at Mellö! Us Weekly and Yahoo have affiliate partnerships. We receive compensation when you click on a link and make a purchase. Learn more!
Time of India
14-07-2025
- Health
- Time of India
Magnesium vs Melatonin: Which supplement is better for nerves, sleep, and overall health, and why
Sleep is vital for human health, and yet more than 60% of adults experience poor quality. Lack of sleep can contribute to chronic disease, including cardiovascular disease and diabetes. Tired of too many ads? go ad free now Stress, diet, poor sleep habits, mental health conditions, and medical conditions may affect sleep. To reclaim restful sleep, people turn to many remedies. These range from listening to white noise on devices to supplementation. Among the most popular supplements that dominate are magnesium and melatonin. These supplements work in different ways and offer unique benefits. But is one more effective than the other? Let's take a look. Role of magnesium Magnesium is an essential mineral commonly found on Earth and in the foods we eat. This mineral is responsible for over 300 bodily functions. It helps in the regulation of blood sugar, blood pressure, and normal heart rhythm. Magnesium also calms the nerves after a long day to help you sleep better. It will make you feel more energized and also keep your heart healthy. It's found naturally in foods like leafy greens, nuts, and whole grains. Role of melatonin Melatonin is a hormone that the brain produces. This hormone is in control of the body's sleep-wake cycle, called the circadian rhythm. Melatonin is produced in response to darkness. It's often taken as a supplement to combat insomnia or adjust sleep patterns, especially for shift workers or those with jet lag. Magnesium supplements Magnesium helps with sleep and also calms the nervous system and relaxes the muscles. It acts as a natural calcium channel blocker, preventing overstimulation of nerves that can lead to anxiety or muscle spasms. Tired of too many ads? go ad free now It also decreases the level of the stress hormone cortisol, which promotes relaxation. There are many types of magnesium supplements present in the market, including magnesium oxide, hydroxide, citrate, glycinate, taurate, sulfate, chloride, threonate, and aspartate. Magnesium supports sleep by relaxing muscles and calming the nervous system. It also helps regulate gamma-aminobutyric acid (GABA), a neurotransmitter that promotes relaxation. Melatonin supplements Melatonin supplements too promote sleep, however, it has less direct impact on nerve health. Though taking melatonin supplementation may reduce stress-related nerve activity by promoting relaxation through better sleep, its primary role is hormonal, not neurological. Melatonin may improve symptoms of , such as fatigue, trouble sleeping, and an upset stomach. It may also help people who are working on the night shift to stay alert and sleep during the day. It is also used to treat conditions such as delayed sleep-wake phase disorder, some sleep disorders in children, and anxiety before and after surgery. Which is better? (Pic courtesy: iStock) Magnesium has been shown to improve and reduce mild anxiety. It also helps to relieve muscle tension and thereby contributes to a relaxed and restful sleep. It is also a cost-effective option. However, magnesium usually takes several weeks to see a visible improvement. These supplements could also lead to side effects such as diarrhea, nausea, and stomach cramps, especially when taken at higher doses. It can also interact with some of the common medications. Melatonin supplements, on the other hand, act quickly compared to magnesium. It promotes sleep within hours of taking it. It helps you to fall asleep faster. Hence, it may be beneficial for people working odd shifts. Despite its quick action, there is not enough to support its long-term safety. The effects of the melatonin supplement will also vary based on the dosage and time you take it. This supplement may also interact with common medications such as antibiotics, birth control pills, and antidepressants. Magnesium Oil Foot Ritual Gains Popularity for Health Benefits Magnesium and melatonin have unique advantages for nerves, sleep, and overall health. Which is best really depends on understanding your specific needs. You can make an informed decision about which supplement or combination best supports your well-being. It is important to consult with your doctor before starting any new supplement.
