On GPS: Jurassic Park … in real life?
Fareed talks with Ben Lamm, the CEO of Colossal Biosciences, who says the company has used gene editing to bring the extinct dire wolf back.
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Medscape
25 minutes ago
- Medscape
Tool Predicts if Seniors with Cancer Can Stay Home Post Op
TOPLINE: A novel predictive model named STAYHOME effectively estimated the risk of losing the ability to live at home among older adults after cancer surgery, demonstrating good calibration with minimal deviation from observed risks. The model predicted a 2.4% and 3.4% risk for admission to a nursing home at 6 months and 12 months, respectively. METHODOLOGY: Older adults prioritize long-term functional independence, and the ability to return and stay at home after cancer surgery remains a key concern. However, current prognostic tools focus on short-term outcomes, lacking individualized long-term risk estimates. To estimate the risk of losing the ability to live at home post-surgery, researchers developed and internally validated a risk prediction model, named STAYHOME, among 97,353 community-dwelling older adults (median age, 76 years) who underwent cancer surgery between 2007 and 2019. The predictive model included preoperative variables such as age, sex, rural residence, previous cancer diagnosis, surgery type, frailty, receipt of home care support, receipt of neoadjuvant therapy, cancer site, and cancer stage. The primary outcome was the inability to stay at home after cancer surgery, defined as the time to admission to a nursing home, and was measured at 6 months and 12 months. TAKEAWAY: Overall, 2658 patients (2.7%) at 6 months and 3746 (3.8%) at 12 months were admitted to a nursing home post-surgery. The mean predicted risk of not staying home was 2.4% at 6 months and 3.4% at 12 months. The STAYHOME tool demonstrated a strong predictive capability, with areas under the curve of 0.76 and 0.75 for 6- and 12-month predictions, respectively. The tool also demonstrated minimal deviation from the observed risk for 6-month (0.33 percentage point on average; calibration slope, 1.27) and 12-month (0.46 percentage point on average; calibration slope, 1.17) predictions. The model's calibration was excellent for most predictors at 6 months and 12 months, with a deviation of < 0.8 percentage points from the observed probability; only age older than 85 years (1.13%), preoperative frailty (1.16%), and receipt of preoperative home care support (1.25%) exceeded the deviation of 1 percentage point at 12 months. Across risk deciles, deviations between predicted and observed probabilities were 0.1%-1.5% at 6 months and 0.1%-1.9% at 12 months, reflecting good calibration. The deviation for the slight overestimation at or above the seventh decile remained under 2% for both timepoints. IN PRACTICE: 'The STAYHOME tool demonstrated good discrimination and was well calibrated. Thus, it may be a useful tool to identify a specific group of individuals at risk of not remaining home,' the authors wrote. '[The tool] used information readily available to patients, care partners, and healthcare professionals and may be implemented to provide them with individualized risk estimates and improve surgical oncology care delivery and experience for older adults,' they concluded. SOURCE: This study, led by Julie Hallet, MD, Odette Cancer Centre, Sunnybrook Health Sciences Centre in Toronto, Ontario, Canada, was published online in JAMA Surgery. LIMITATIONS: The STAYHOME tool showed slightly reduced discrimination for predictor levels of preoperative frailty, preoperative home care use, receipt of neoadjuvant therapy, and having stage IV disease. The model was also less well calibrated at the extremes of the risk distribution, with a slight overestimation in higher-risk categories. DISCLOSURES: This study was funded by operating grants from the Canadian Institutes for Health Research, Ontario Cancer Research Institute, and ICES. One author reported receiving speaker fees from Ipsen, outside the submitted work. This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Yahoo
38 minutes ago
- Yahoo
Blue Origin launches 6 tourists on suborbital trip from Texas, including 750th person ever to fly into space
When you buy through links on our articles, Future and its syndication partners may earn a commission. Blue Origin sent its 70th person into space today (June 29) on its 13th rocket flight to carry passengers. The company's New Shepard suborbital launch vehicle lifted off Saturday at 9:39 a.m. CDT (10:39 a.m. EDT or 1439 GMT) from its Launch Site One in West Texas. On board were husband and wife Allie and Carl Kuehner, Leland Larson, Freddie Rescigno, Jr., Owolabi Salis and James Sitkin. Carl Kuehner became Blue Origin's astronaut number 70, which based on prior precedent, was determined by the seat on board the New Shepard capsule that he assigned for the flight. He also became the 750th person in history to reach space, as recorded by the Association of Space Explorers' Registry of Space Travelers. The 10-minute NS-33 mission — numbered such as this was Blue Origin's 33rd New Shepard flight overall — went to plan, with both the propulsion module (Tail 5) making a safe vertical landing and the crew capsule, named "RSS Kármán Line," returning the passengers to a parachute-slowed, air thruster-cushioned touchdown not far from where they launched. For about three minutes as the gumdrop-shaped capsule reached its apogee, or highest point away from Earth, the Kuehners, Larson, Rescigno, Salis and Sitkin experienced weightlessness and saw the curvature of the planet set against the stark blackness of space. The flight reached a 345,044 feet (105.2 km) above the ground, surpassing the Kármán Line, the internationally-accepted boundary between Earth and space at 62 miles high (100 kilometers). Flying along with the crew were more than 1,000 physical and digital postcards designed by students and the public, as collected by The Museum of Flight in Seattle and Parkcrest Elementary in Burnaby, British Columbia, Canada. The cards are part of an on going project by Blue Origin's non-profit organization Club For the Future. As with all New Shepard fights, the cost per seat on NS-33 was not disclosed. The passengers included an environmentalist, the chairman of a real estate development firm, the former CEO of a public transportation company, an electrical wire and cable distributor, and two attorneys. The six NS-33 passengers dubbed themselves "The Solstice 33," as they were originally scheduled to launch on the summer solstice (June 21) but were delayed by poor weather conditions. Their flight brought the total number of people who have flown on suborbital flights to 123, according to the Association of Space Explorers.
Yahoo
38 minutes ago
- Yahoo
Doubleheader rocket launches in Florida before July 4? When to see in Vero, Fort Pierce, Port St. Lucie
Doubleheader rocket launch in Florida hours apart? That's the plan for NASA and Cape Canaveral. If all goes according to plan for SpaceX, another doubleheader rocket launch may be on the horizon for Tuesday, July 1, ahead of the Independence Day holiday. Liftoff will potentially occur at Kennedy Space Center and nearby Cape Canaveral Space Force Station. Though rockets launch in Florida from NASA's Kennedy Space Center or Cape Canaveral Space Force Station, people beyond the area can sometimes see this phenomenon. Weather permitting and depending on cloud cover, a rocket launch from Florida's Space Coast could be visible as far north as Jacksonville Beach and Daytona Beach to as far south as Vero Beach and West Palm Beach. When there's a launch window in the middle of the night or very early morning, there's an opportunity for unique photos — the rocket lights up the dark sky and the contrail after makes for a great photo. Below is more information about the SpaceX rocket launches in Florida, a list of doubleheader rocket launches and suggestions on where to watch them. Rocket launch tally: Here's a list of all 2025 missions from Cape Canaveral, Florida (psst, there's a lot) For questions or comments, email FLORIDA TODAY Space Reporter Rick Neale at rneale@ or Space Reporter Brooke Edwards at bedwards@ For more space news from the USA TODAY Network, visit Mission: A SpaceX Falcon 9 rocket will launch a payload of Starlink broadband satellites into low-Earth orbit, a Federal Aviation Administration operations plan advisory shows. Launch window: 1:52 a.m. to 6:22 a.m. ET Tuesday, July 1, 2025 Launch location: Launch Complex 40 at Cape Canaveral Space Force Station in Cape Canaveral, Florida Sonic booms for the Space Coast of Florida: No Trajectory: Northeast Live coverage starts 90 minutes before liftoff at : You can watch live rocket launch coverage from USA TODAY Network's Space Team, which consists of FLORIDA TODAY space reporters Rick Neale and Brooke Edwards and visuals journalists Craig Bailey, Malcolm Denemark and Tim Shortt. Our Space Team will provide up-to-the-minute updates in a mobile-friendly live blog, complete with a countdown clock, at starting 90 minutes before liftoff. You can download the free FLORIDA TODAY app, which is available in the App Store or Google Play, or type into your browser. Mission: A SpaceX Falcon 9 rocket will launch the European Space Agency's Meteosat Third Generation Sounder satellite into orbit, a Federal Aviation Administration operations plan advisory shows. Launch window: 5:03 p.m. to 8:15 p.m. ET Tuesday, July 1, 2025 Launch location: Launch pad 39A at NASA's Kennedy Space Center near Cape Canaveral, Florida Sonic booms from the Space Coast of Florida: No Trajectory: TBA Live coverage starts 90 minutes before liftoff at : You can watch live rocket launch coverage from USA TODAY Network's Space Team, which consists of FLORIDA TODAY space reporters Rick Neale and Brooke Edwards and visuals journalists Craig Bailey, Malcolm Denemark and Tim Shortt. Our Space Team will provide up-to-the-minute updates in a mobile-friendly live blog, complete with a countdown clock, at starting 90 minutes before liftoff. You can download the free FLORIDA TODAY app, which is available in the App Store or Google Play, or type into your browser. As of Monday, June 30, 2025, there have been 54 rocket launches from NASA's Kennedy Space Center and Cape Canaveral Space Force Station in Cape Canaveral, Florida. Of the 54 rocket launches, some of which have included crew members en route to the International Space Station, seven have been "doubleheaders," or two in one day. Here's a look back at those missions. Tuesday, Feb. 4, 2025: For the SpaceX Starlink 12-3 mission, a Falcon 9 rocket launched at 5:15 a.m. Feb. 4, 2025, from Cape Canaveral Space Force Station, followed by a 6:13 p.m. Feb. 4, 2025, launch for SpaceX Maxar 3 mission from NASA's Kennedy Space Center. Wednesday, Feb. 26, 2025: For the SpaceX Intuitive Machines IM-2 mission, a Falcon 9 rocket launched at 7:16 p.m. Feb. 26, 2025, from NASA's Kennedy Space Center, followed by a 10:34 p.m. Feb. 26, 2025, launch for SpaceX Starlink 12-13 from Cape Canaveral Space Force Station. Monday, March 31, 2025: For the SpaceX Starlink 6-80 mission, a Falcon 9 rocket launched at 3:52 p.m. March 31, 2025, from Cape Canaveral Space Force Station, followed by a 9:46 p.m. March 31, 2025, launch for SpaceX Fram2 from NASA's Kennedy Space Center. Monday, April 21, 2025: For the NASA-SpaceX CRS-32 mission, a Falcon 9 rocket launched at 4:15 a.m. April 21, 2025, from NASA's Kennedy Space Center, followed by a 8:48 p.m. April 21, 2025, launch for SpaceX Bandwagon-3 from Cape Canaveral Space Force Station. Monday, April 28, 2025: For United Launch Alliance's first Project Kuiper mission, an Atlas V rocket launched at 7:01 p.m. April 28, 2025, from Cape Canaveral Space Force Station, followed by a 10:34 p.m. April 28, 2025, launch of the Falcon 9 rocket for SpaceX Starlink 12-10 from NASA's Kennedy Space Center. Monday, June 23, 2025: For the SpaceX Starlink 10-23 mission, a Falcon 9 rocket launched at 1:58 a.m. June 23, 2025, from Launch Complex 40 at Cape Canaveral Space Force Station, followed by a 6:54 a.m. June 23, 2025, United Launch Alliance-Amazon Project Kuiper 2 launch of the Atlas V rocket from Launch Complex 41 at Cape Canaveral Space Force Station. Wednesday, June 25, 2025: For the SpaceX-Axiom Space Mission 4 (Ax-4), after multiple delays, the fourth astronaut crew of Axiom Space finally took off for the International Space Station at 2:31 a.m. June 25, 2025. It was the first flight of a brand new SpaceX Dragon, which was named Grace. SpaceX launched Axiom Space crew from NASA's Kennedy Space Center in Florida. SpaceX Starlink 10-16 mission followed at 3:54 p.m. June 25, 2025, from Launch Complex 40 at Cape Canaveral Space Force Station. The payload was 27 Starlink internet satellites. FLORIDA TODAY's Space Team consistently covers rocket launches from NASA's Kennedy Space Center and Cape Canaveral Space Force Station for the USA TODAY Network. Of the seven doubleheader rocket launches in Florida for 2025, four happened on a Monday, and only one occurred at the same launch complex station location on the same day (June 23 SpaceX and ULA missions). Coincidentally, the ULA-Amazon Project Kuiper launches each happened on a Monday, and both fell on a doubleheader rocket launch day. Sebastian Inlet State Park, 9700 S. State Road A1A, Melbourne Beach, Florida (cost to enter) Wabasso Beach Park, 1808 Wabasso Beach Road, Wabasso, Florida Ambersands Beach Park, 12566 N. SR A1A, Vero Beach, Florida (free parking) South Beach Park, 1700 Ocean Drive, Vero Beach, Florida (free parking) Merrill Barber Bridge in Vero Beach, Florida Alma Lee Loy Bridge in Vero Beach, Florida Fort Pierce Inlet State Park, 905 Shorewinds Drive, Fort Pierce, Florida Blind Creek Beachside North and South, 5460 S. Ocean Drive, Fort Pierce, Florida Blue Heron Beach, 2101 Blue Heron Blvd., Fort Pierce, Florida Frederick Douglass Memorial Park, 3600 S. Ocean Drive, Fort Pierce, Florida Dollman Park Beachside, 9200 S. Ocean Drive, Jensen Beach, Florida Herman's Bay Beach, 7880 S. Ocean Drive, Jensen Beach, Florida John Brooks Park Beachside, 3300 S. Ocean Drive, Fort Pierce, Florida Middle Cove Beach, 4600 S. Ocean Drive, Fort Pierce, Florida Normandy Beach in Jensen Beach, Florida Pepper Park Beachside, 3302 N. SR A1A, Fort Pierce, Florida Walton Rocks Beach, 6700 S. Ocean Drive, Jensen Beach, Florida (dog park) Waveland Beach, 10350 S. Ocean Drive, Jensen Beach, Florida State Road A1A causeway in Stuart, Florida House of Refuge and beach, 301 S.E. MacArthur Blvd., Stuart, Florida This article originally appeared on Treasure Coast Newspapers: SpaceX rocket launches: Where to watch from Treasure Coast, Florida
