
Ozzy Osbourne: What is Parkinson's disease?
Parkinson's is a progressive neurological condition caused by the death of nerve cells in the brain that create the chemical dopamine.
– What are the symptoms?
People begin to develop symptoms of Parkinson's when the brain is no longer able to make enough dopamine to adequately control movement.
The three main symptoms are tremor (shaking), slowness of movement and rigidity (muscle stiffness).
Subtle changes in a person's walking pattern could be an early sign of Parkinson's disease.
Some people develop very small handwriting, a loss in their sense of smell, nerve pain or insomnia.
Symptoms usually develop slowly over several years.
– Can it be treated?
There is currently no cure for Parkinson's disease.
Treatments include drugs such as levodopa, dopamine agonists and monoamine oxidase-B inhibitors.
Levodopa is absorbed by the nerve cells in the brain and turned into dopamine.
Increasing the levels of dopamine in this way usually cuts down problems with movement.
Other therapies include physiotherapy and, in some cases, surgery.
– What does Parkinson's UK say?
Chief executive Caroline Rassell said: 'News of Ozzy Osbourne's death, so soon after his celebratory homecoming show, will come as a shock to so many.
'By speaking openly about both his diagnosis and life with Parkinson's, Ozzy and all his family helped so many families in the same situation.
'They normalised tough conversations and made others feel less alone with a condition that's on the rise and affecting more people every day.
'All of our heartfelt thoughts are with his family, friends and fans worldwide. His memory and the impact he left on the world will live on in all of them.'

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Daily Mirror
2 days ago
- Daily Mirror
Universal Credit changes 'may see lower payments for people with six conditions'
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However, anti-poverty charity Z2K has identified at least six health conditions that may be adversely affected by the changes. These include: Autism Schizophrenia Dementia Bipolar disorder Multiple sclerosis Parkinson's Furthermore, a select committee report on the matter mentions ME, Premenstrual Dysphoric Disorder (PMDD), and eating disorders as having the potential to be impacted. The assessment for claimants will focus on the effects of their condition rather than the condition itself. No conditions are automatically excluded from the "severe conditions" criteria, which will apply to all health conditions and disabilities. Ayla Ozmen, director of policy and campaigns at Z2K, warned The Sun: "Disabled people with conditions like Parkinsons, schizophrenia and multiple sclerosis are at risk of losing out on over £200 per month as a result of cuts to the Universal Credit health element which have been approved by parliament. "Contrary to government claims, we fear that many of the disabled people affected will never be able to work because of their conditions. We're calling on the government to clarify how it will ensure that disabled people with severe conditions will be protected under these plans." In response to welfare critics, a Government spokesperson said: "Our welfare reforms will support those who can work into jobs and ensure there is always a safety net for those that need it. Our assessment of the pact indicates that our reforms will lift 50,000 children out of poverty – and our additional employment support will elevate even more families from poverty. "The reforms will recalibrate Universal Credit rates to eliminate the perverse incentives that keep people out of work, whilst genuinely assisting disabled individuals and those with long-term health conditions into good, secure work – supported by £3.8billion in employment support over this parliament. "We are also addressing poverty by extending free school meals to all households on Universal Credit, helping to tackle holiday hunger with our Crisis and Resilience Fund, supporting over a million households by introducing a Fair Repayment Rate on Universal Credit deductions, and delivering the largest increase in social and affordable housebuilding in a generation, as part of our Plan for Change."


Scottish Sun
3 days ago
- Scottish Sun
From gangrene to deadly liver damage – the 92 conditions linked to going to bed after a specific time
Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) GOING to sleep past a specific time could up the risk of 92 conditions, scientists have suggested. This includes gangrene, liver damage, Parkinson's disease and type 2 diabetes, according to Chinese researchers. Sign up for Scottish Sun newsletter Sign up 1 Going to sleep after 12:30 could up your risk of certain conditions, scientists say Credit: Getty It's no secret that persistent poor sleep can impact your health, with studies showing it may increase the likelihood of developing dementia, heart disease, diabetes, obesity and even cancer. But much of this research focuses on sleep duration – how many hours of kip participants get a night – rather than factors like bedtime and how well people sleep through the night. Now, scientists from Peking University and Army Medical University say going to sleep past 12:30am may increase the risk of ill health. "Evidence suggests that sleep traits might be associated with a number of diseases affecting diverse systems, such as cardiovascular diseases, metabolic disorders, and mental diseases," researchers wrote in Health Data Science. "However, in most publications to date, sleep has been measured by subjective recall of the participants, which has been found to bear systematic error in some aspects and may lead to misunderstanding of sleep's health impact. "Furthermore, the available literature has mainly focused on certain sleep traits, namely, sleep duration, while other traits such as sleep timing and sleep rhythm have less often been analysed." They said sleep regularity - such as going to bed at a consistent time and having stable circadian rhythms - is a little known but critical factor in disease risk. Researchers used data from 88,461 adults who took part in the UK Biobank study. Participants wore small sensors called accelerometers, which collected data on their bedtime, how long they slept a night and whether they woke up, for an average of about seven years. Scientists paired this information with data from NHS records, cancer registries and the National Death Index. I spent three days at a sleep retreat - these are the top 7 things I learnt They found that sleep habits picked up through the accelerometers played a significant role in the risk of developing certain diseases. Researchers studied 172 diseases. Researchers found that poor sleep habits can double the risk of certain diseases. For example, participants with the most irregular sleep patterns had more than double the risk of gangrene compared to those with consistent sleep routines Meanwhile, people who went to sleep after 12:30am had over double the risk of liver problems such as fibrosis and cirrhosis, compared to those who went to bed between 11:00 and 11:30 pm. For 92 diseases, at least 20 per cent of the risk was due to sleep traits and for 44 diseases, more than 30 per cent of the risk was linked to sleep factors. Examples included: Parkinson's disease, where the risk was linked to how consistent sleep was each day. Heart disease, where the risk was tied to balance between activity and rest. Type 2 diabetes, where the risk was linked to regular sleep timing. Obesity, where the risk was tied to balance between activity and rest. Overactive thyroid, where bedtime played a role. Urinary incontinence, where risk was linked to sleep quality. How bad sleep affects weight Previously in The Sun, experts explained how sleep is closely linked with weight. Disrupts hunger hormones Ghrelin is a hormone released after the brain signals the stomach is empty, while leptin is released from fat cells to suppress hunger - and tell the brain it's full. Studies have shown that when you don't get enough shut-eye, the body makes more ghrelin and less leptin - leaving you more hungry. One study of 12 men led by University of Chicago showed two days of sleep deprivation drove leptin levels in the blood down by 18 per cent, while increasing ghrelin by 28 per cent. The men reported a 24 per cent increase in their hunger and appetite compared to when they were given two restful nights. More time to eat The less you are asleep, the more you are awake. This gives more of an opportunity to eat. In the modern day world, people are awake for up to 17 hours at a time - 7am till 12pm. It leaves a huge window for being awake and eating. If you're struggling with both your weight and sleep, try finishing your meals three to four hours before bed time. That might mean limiting your eating window from 9am until 6pm. Reach for takeaways If you have a weird sleeping pattern, chances are your eating schedule is also off-whack. Struggling to sleep can see us turn to convenience - takeaways, ready meals, oven foods and more, whi;e being energised gives us more motivation to cook healthily. Eat more calories than normal Studies suggest that the less sleep you get, the more calorie-dense food you choose to eat. One study in Chicago found that men ate more food at a buffet after four consecutive night's of rough sleep compared with when they were rested. They consumed around 340 calories more, mostly because they ate more snacks and carbohydrate-rich food. Researchers from King's College London also found that adults consumed an additional 385 calories – the equivalent of one and a half Mars Bars – on days after they were deprived of kip by combining the results of 11 previous studies. More desire for food Foods, especially those high in calories, are more appetising when we are sleep deprived because we subconsciously know they will boost our energy. A German study showed the lengths sleepy people would go to for calorific snacks using 32 healthy men. After a normal dinner and either a restful or restless night's sleep, the men were given three Euros to spend on snacks and told to bid the maximum amount they were willing to spend on each item. When sleep deprived. participants were willing to pay extra for the junk food items - which they were allowed to eat afterwards - suggesting a stronger desire. Fat storage more likely Scientists have warned that not getting enough sleep changes how the body deals with food, which could then lead to weight gain. One study showed that men who ate a large bowl of chilli mac and cheese after four nights of bad sleep reacted differently to the food than those who were well-rested. Researchers at Pennsylvania State University said blood tests showed lipids (fats) from foods were cleared faster, suggesting they were being stored almost instantly. The process did not spring back to its normal rate even after the men were given a long night's sleep. The study also challenged previous claims that sleeping over nine hours each night is harmful. Previous research has suggested "long sleepers" could be at higher risk of stroke and heart disease. Researchers said "misclassification" may be to blame, as 21 per cent of 'long sleepers' actually slept less than six hours, suggesting that time spent in bed is often confused with actual sleep time. Prof Shengfeng Wang, senior author of the study, said: 'Our findings underscore the overlooked importance of sleep regularity. 'It's time we broaden our definition of good sleep beyond just duration.' The study team suggested that inflammation could be upping the risk of disease in people who sleep poorly, as disrupted sleep might trigger immune responses that contribute to illness. Researchers concluded: "Our results may suggest that the various dimensions of sleep traits deserve more attention in future studies and that pursuing comprehensive control of sleep traits may have greater benefit for health over merely ensuring adequate sleep duration." Fortunately, there are easy things we can do to correct some – if not all – our poor sleep habits, they suggested. "For example, the disruption of sleep rhythm can be substantially improved if the unhealthy habit of social media use before sleep (so-called Twitter jetlag) can be corrected," they said. Next, the team will look into whether sleep improvements can reduce the risk of disease over time.


Daily Mail
4 days ago
- Daily Mail
Major study finds link between bad habit practiced by 70million Americans and more than 170 diseases
People who repeatedly suffer from poor sleeping habits could be at greater risk of more than 170 diseases, ranging from gangrene to dementia, a groundbreaking new study suggests. The research, led by teams from Peking University and the Army Medical University in China, analyzed objective sleep data from 88,460 adults who took part in a nationwide survey run by the UK Biobank platform. The participants answered over 160 questions about their sleeping habits, including their ability to fall to sleep, their hours of sleep per night, their quality of sleep and associated lifestyle and behaviors. From an in-depth analysis of the results, the researchers found significant associations between various sleep traits and 172 diseases. The included participants were on average 62 years old, and 43 percent were males. Using data from a wearable device worn over an average of about seven years, researchers identified that 92 diseases had over 20 percent of their risk attributable to poor sleep behavior. Notably, irregular bedtime, defined in the study as falling asleep after 12:30AM, was linked to a 2.6-fold higher risk of liver cirrhosis, while inconsistent sleeping patterns increased the risk of gangrene, death of body tissue, by 2.6 times. A total of 42 diseases exhibited over two-fold risk associated with certain sleep traits such as sleep quality, quantity and consistency. These conditions included Parkinson's disease, age-related frailty, gangrene, fibrosis and cirrhosis of liver. Meanwhile, 122 diseases had at least 1.5-fold risk, including type 2 diabetes, respiratory failure, bone and spine fractures and urinary incontinence. Among the 172 diseases found to be associated with sleep, up to 52 percent of the risk of a single disease could be attributed to a sleep trait. Ninety-two diseases had over a 20 percent risk attributable to at least one sleep trait, and 44 diseases had one attributable risk over 30 percent. Some common diseases showed considerable attributable risk, such as Parkinson's disease (37 percent by caused by inconsistent sleeping patterns) and urinary incontinence (24 percent by how much time you spend asleep while in bed). Importantly, the study challenges previous claims that 'long sleep' (more than nine hours) is harmful. While subjective reports have linked long sleep to stroke and heart disease, objective data in the most recent study revealed this association only with heart disease. Misclassification may be to blame, the researchers say. Just over 21 percent of 'long sleepers' actually slept less than six hours, suggesting that time spent in bed is often confused with actual sleep time. Recommended guidelines suggest seven to nine hours is the ideal sleep time for adults. 'Our findings underscore the overlooked importance of sleep regularity,' said Prof. Shengfeng Wang, senior author of the study. 'It's time we broaden our definition of good sleep beyond just duration.' Looking ahead, the researchers want to look at the impact of sleep treatment plans on chronic disease outcomes. Dr Chris Winter, a neurologist specializing in sleep, previously told the link between poor sleep and health issues are 'probably multi-factorial.' He said that sleeping too little causes the nervous system to malfunction, leading to a higher heart rate, high blood pressure, and elevated stress levels. Poor sleep can also exacerbate inflammation in the body, a well-known risk factor for cardiovascular disease, stroke, dementia, and autoimmune diseases like rheumatoid arthritis. Weight and metabolism are also impacted when a person sleeps too poorly, as diet tends to suffer. Sleep's effects on hormones mean people are likely to make unhealthier food choices. Dr Beth Frates, director of lifestyle medicine and wellness in the Department of Surgery at Massachusetts General Hospital, said: 'Most people focus on exercise and diet when it comes to weight management and a healthy heart, but few focus on sleep. 'Working to find ways to clean up sleep hygiene may help people to extend sleep time to the recommended seven to nine hours per night. 'This could, in turn, lead to consuming fewer calories and even weight loss in people who are in the overweight category by BMI.' In another study examining the risk to heart health published in the Journal of the American Heart Association, researchers found that middle-aged adults with conditions like high blood pressure, type 2 diabetes, heart disease, or stroke may face a higher risk of cancer and premature death if they sleep less than six hours a night. It is known that the effects of poor sleep can be felt immediately, and after around three days of too little sleep, a person can develop hallucinations or psychosis. It can also lead to an increased risk of death by accident or injury. Almost 20 percent of all serious car crash injuries among the general public are associated with driver sleepiness, independent of alcohol effects. Compared to drivers who had slept for a regular seven hours, those who reported they'd slept fewer were 1.3 times more likely to crash, while those who slept five to six hours were nearly two times as likely to crash.