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Major study finds link between bad habit practiced by 70million Americans and more than 170 diseases

Major study finds link between bad habit practiced by 70million Americans and more than 170 diseases

Daily Mail​3 days ago
People who repeatedly suffer from poor sleeping habits could be at greater risk of more than 170 diseases, ranging from gangrene to dementia, a groundbreaking new study suggests.
The research, led by teams from Peking University and the Army Medical University in China, analyzed objective sleep data from 88,460 adults who took part in a nationwide survey run by the UK Biobank platform.
The participants answered over 160 questions about their sleeping habits, including their ability to fall to sleep, their hours of sleep per night, their quality of sleep and associated lifestyle and behaviors.
From an in-depth analysis of the results, the researchers found significant associations between various sleep traits and 172 diseases.
The included participants were on average 62 years old, and 43 percent were males.
Using data from a wearable device worn over an average of about seven years, researchers identified that 92 diseases had over 20 percent of their risk attributable to poor sleep behavior.
Notably, irregular bedtime, defined in the study as falling asleep after 12:30AM, was linked to a 2.6-fold higher risk of liver cirrhosis, while inconsistent sleeping patterns increased the risk of gangrene, death of body tissue, by 2.6 times.
A total of 42 diseases exhibited over two-fold risk associated with certain sleep traits such as sleep quality, quantity and consistency. These conditions included Parkinson's disease, age-related frailty, gangrene, fibrosis and cirrhosis of liver.
Meanwhile, 122 diseases had at least 1.5-fold risk, including type 2 diabetes, respiratory failure, bone and spine fractures and urinary incontinence.
Among the 172 diseases found to be associated with sleep, up to 52 percent of the risk of a single disease could be attributed to a sleep trait.
Ninety-two diseases had over a 20 percent risk attributable to at least one sleep trait, and 44 diseases had one attributable risk over 30 percent.
Some common diseases showed considerable attributable risk, such as Parkinson's disease (37 percent by caused by inconsistent sleeping patterns) and urinary incontinence (24 percent by how much time you spend asleep while in bed).
Importantly, the study challenges previous claims that 'long sleep' (more than nine hours) is harmful.
While subjective reports have linked long sleep to stroke and heart disease, objective data in the most recent study revealed this association only with heart disease.
Misclassification may be to blame, the researchers say.
Just over 21 percent of 'long sleepers' actually slept less than six hours, suggesting that time spent in bed is often confused with actual sleep time.
Recommended guidelines suggest seven to nine hours is the ideal sleep time for adults.
'Our findings underscore the overlooked importance of sleep regularity,' said Prof. Shengfeng Wang, senior author of the study.
'It's time we broaden our definition of good sleep beyond just duration.'
Looking ahead, the researchers want to look at the impact of sleep treatment plans on chronic disease outcomes.
Dr Chris Winter, a neurologist specializing in sleep, previously told DailyMail.com the link between poor sleep and health issues are 'probably multi-factorial.'
He said that sleeping too little causes the nervous system to malfunction, leading to a higher heart rate, high blood pressure, and elevated stress levels.
Poor sleep can also exacerbate inflammation in the body, a well-known risk factor for cardiovascular disease, stroke, dementia, and autoimmune diseases like rheumatoid arthritis.
Weight and metabolism are also impacted when a person sleeps too poorly, as diet tends to suffer.
Sleep's effects on hormones mean people are likely to make unhealthier food choices.
Dr Beth Frates, director of lifestyle medicine and wellness in the Department of Surgery at Massachusetts General Hospital, said: 'Most people focus on exercise and diet when it comes to weight management and a healthy heart, but few focus on sleep.
'Working to find ways to clean up sleep hygiene may help people to extend sleep time to the recommended seven to nine hours per night.
'This could, in turn, lead to consuming fewer calories and even weight loss in people who are in the overweight category by BMI.'
In another study examining the risk to heart health published in the Journal of the American Heart Association, researchers found that middle-aged adults with conditions like high blood pressure, type 2 diabetes, heart disease, or stroke may face a higher risk of cancer and premature death if they sleep less than six hours a night.
It is known that the effects of poor sleep can be felt immediately, and after around three days of too little sleep, a person can develop hallucinations or psychosis.
It can also lead to an increased risk of death by accident or injury. Almost 20 percent of all serious car crash injuries among the general public are associated with driver sleepiness, independent of alcohol effects.
Compared to drivers who had slept for a regular seven hours, those who reported they'd slept fewer were 1.3 times more likely to crash, while those who slept five to six hours were nearly two times as likely to crash.
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From gangrene to deadly liver damage – the 92 conditions linked to going to bed after a specific time
From gangrene to deadly liver damage – the 92 conditions linked to going to bed after a specific time

Scottish Sun

time2 days ago

  • Scottish Sun

From gangrene to deadly liver damage – the 92 conditions linked to going to bed after a specific time

Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) GOING to sleep past a specific time could up the risk of 92 conditions, scientists have suggested. This includes gangrene, liver damage, Parkinson's disease and type 2 diabetes, according to Chinese researchers. Sign up for Scottish Sun newsletter Sign up 1 Going to sleep after 12:30 could up your risk of certain conditions, scientists say Credit: Getty It's no secret that persistent poor sleep can impact your health, with studies showing it may increase the likelihood of developing dementia, heart disease, diabetes, obesity and even cancer. But much of this research focuses on sleep duration – how many hours of kip participants get a night – rather than factors like bedtime and how well people sleep through the night. Now, scientists from Peking University and Army Medical University say going to sleep past 12:30am may increase the risk of ill health. "Evidence suggests that sleep traits might be associated with a number of diseases affecting diverse systems, such as cardiovascular diseases, metabolic disorders, and mental diseases," researchers wrote in Health Data Science. "However, in most publications to date, sleep has been measured by subjective recall of the participants, which has been found to bear systematic error in some aspects and may lead to misunderstanding of sleep's health impact. "Furthermore, the available literature has mainly focused on certain sleep traits, namely, sleep duration, while other traits such as sleep timing and sleep rhythm have less often been analysed." They said sleep regularity - such as going to bed at a consistent time and having stable circadian rhythms - is a little known but critical factor in disease risk. Researchers used data from 88,461 adults who took part in the UK Biobank study. Participants wore small sensors called accelerometers, which collected data on their bedtime, how long they slept a night and whether they woke up, for an average of about seven years. Scientists paired this information with data from NHS records, cancer registries and the National Death Index. I spent three days at a sleep retreat - these are the top 7 things I learnt They found that sleep habits picked up through the accelerometers played a significant role in the risk of developing certain diseases. Researchers studied 172 diseases. Researchers found that poor sleep habits can double the risk of certain diseases. For example, participants with the most irregular sleep patterns had more than double the risk of gangrene compared to those with consistent sleep routines Meanwhile, people who went to sleep after 12:30am had over double the risk of liver problems such as fibrosis and cirrhosis, compared to those who went to bed between 11:00 and 11:30 pm. For 92 diseases, at least 20 per cent of the risk was due to sleep traits and for 44 diseases, more than 30 per cent of the risk was linked to sleep factors. Examples included: Parkinson's disease, where the risk was linked to how consistent sleep was each day. Heart disease, where the risk was tied to balance between activity and rest. Type 2 diabetes, where the risk was linked to regular sleep timing. Obesity, where the risk was tied to balance between activity and rest. Overactive thyroid, where bedtime played a role. Urinary incontinence, where risk was linked to sleep quality. How bad sleep affects weight Previously in The Sun, experts explained how sleep is closely linked with weight. Disrupts hunger hormones Ghrelin is a hormone released after the brain signals the stomach is empty, while leptin is released from fat cells to suppress hunger - and tell the brain it's full. Studies have shown that when you don't get enough shut-eye, the body makes more ghrelin and less leptin - leaving you more hungry. One study of 12 men led by University of Chicago showed two days of sleep deprivation drove leptin levels in the blood down by 18 per cent, while increasing ghrelin by 28 per cent. The men reported a 24 per cent increase in their hunger and appetite compared to when they were given two restful nights. More time to eat The less you are asleep, the more you are awake. This gives more of an opportunity to eat. In the modern day world, people are awake for up to 17 hours at a time - 7am till 12pm. It leaves a huge window for being awake and eating. If you're struggling with both your weight and sleep, try finishing your meals three to four hours before bed time. That might mean limiting your eating window from 9am until 6pm. Reach for takeaways If you have a weird sleeping pattern, chances are your eating schedule is also off-whack. Struggling to sleep can see us turn to convenience - takeaways, ready meals, oven foods and more, whi;e being energised gives us more motivation to cook healthily. Eat more calories than normal Studies suggest that the less sleep you get, the more calorie-dense food you choose to eat. One study in Chicago found that men ate more food at a buffet after four consecutive night's of rough sleep compared with when they were rested. They consumed around 340 calories more, mostly because they ate more snacks and carbohydrate-rich food. Researchers from King's College London also found that adults consumed an additional 385 calories – the equivalent of one and a half Mars Bars – on days after they were deprived of kip by combining the results of 11 previous studies. More desire for food Foods, especially those high in calories, are more appetising when we are sleep deprived because we subconsciously know they will boost our energy. A German study showed the lengths sleepy people would go to for calorific snacks using 32 healthy men. After a normal dinner and either a restful or restless night's sleep, the men were given three Euros to spend on snacks and told to bid the maximum amount they were willing to spend on each item. When sleep deprived. participants were willing to pay extra for the junk food items - which they were allowed to eat afterwards - suggesting a stronger desire. Fat storage more likely Scientists have warned that not getting enough sleep changes how the body deals with food, which could then lead to weight gain. One study showed that men who ate a large bowl of chilli mac and cheese after four nights of bad sleep reacted differently to the food than those who were well-rested. Researchers at Pennsylvania State University said blood tests showed lipids (fats) from foods were cleared faster, suggesting they were being stored almost instantly. The process did not spring back to its normal rate even after the men were given a long night's sleep. The study also challenged previous claims that sleeping over nine hours each night is harmful. Previous research has suggested "long sleepers" could be at higher risk of stroke and heart disease. Researchers said "misclassification" may be to blame, as 21 per cent of 'long sleepers' actually slept less than six hours, suggesting that time spent in bed is often confused with actual sleep time. Prof Shengfeng Wang, senior author of the study, said: 'Our findings underscore the overlooked importance of sleep regularity. 'It's time we broaden our definition of good sleep beyond just duration.' The study team suggested that inflammation could be upping the risk of disease in people who sleep poorly, as disrupted sleep might trigger immune responses that contribute to illness. Researchers concluded: "Our results may suggest that the various dimensions of sleep traits deserve more attention in future studies and that pursuing comprehensive control of sleep traits may have greater benefit for health over merely ensuring adequate sleep duration." Fortunately, there are easy things we can do to correct some – if not all – our poor sleep habits, they suggested. "For example, the disruption of sleep rhythm can be substantially improved if the unhealthy habit of social media use before sleep (so-called Twitter jetlag) can be corrected," they said. Next, the team will look into whether sleep improvements can reduce the risk of disease over time.

From gangrene to deadly liver damage – the 92 conditions linked to going to bed after a specific time
From gangrene to deadly liver damage – the 92 conditions linked to going to bed after a specific time

The Sun

time2 days ago

  • The Sun

From gangrene to deadly liver damage – the 92 conditions linked to going to bed after a specific time

GOING to sleep past a specific time could up the risk of 92 conditions, scientists have suggested. This includes gangrene, liver damage, Parkinson's disease and type 2 diabetes, according to Chinese researchers. It's no secret that persistent poor sleep can impact your health, with studies showing it may increase the likelihood of developing dementia, heart disease, diabetes, obesity and even cancer. But much of this research focuses on sleep duration – how many hours of kip participants get a night – rather than factors like bedtime and how well people sleep through the night. Now, scientists from Peking University and Army Medical University say going to sleep past 12:30am may increase the risk of ill health. "Evidence suggests that sleep traits might be associated with a number of diseases affecting diverse systems, such as cardiovascular diseases, metabolic disorders, and mental diseases," researchers wrote in Health Data Science. "However, in most publications to date, sleep has been measured by subjective recall of the participants, which has been found to bear systematic error in some aspects and may lead to misunderstanding of sleep's health impact. "Furthermore, the available literature has mainly focused on certain sleep traits, namely, sleep duration, while other traits such as sleep timing and sleep rhythm have less often been analysed." They said sleep regularity - such as going to bed at a consistent time and having stable circadian rhythms - is a little known but critical factor in disease risk. Researchers used data from 88,461 adults who took part in the UK Biobank study. Participants wore small sensors called accelerometers, which collected data on their bedtime, how long they slept a night and whether they woke up, for an average of about seven years. Scientists paired this information with data from NHS records, cancer registries and the National Death Index. I spent three days at a sleep retreat - these are the top 7 things I learnt They found that sleep habits picked up through the accelerometers played a significant role in the risk of developing certain diseases. Researchers studied 172 diseases. Researchers found that poor sleep habits can double the risk of certain diseases. For example, participants with the most irregular sleep patterns had more than double the risk of gangrene compared to those with consistent sleep routines Meanwhile, people who went to sleep after 12:30am had over double the risk of liver problems such as fibrosis and cirrhosis, compared to those who went to bed between 11:00 and 11:30 pm. For 92 diseases, at least 20 per cent of the risk was due to sleep traits and for 44 diseases, more than 30 per cent of the risk was linked to sleep factors. Examples included: Parkinson's disease, where the risk was linked to how consistent sleep was each day. Heart disease, where the risk was tied to balance between activity and rest. Type 2 diabetes, where the risk was linked to regular sleep timing. Obesity, where the risk was tied to balance between activity and rest. Overactive thyroid, where bedtime played a role. Urinary incontinence, where risk was linked to sleep quality. How bad sleep affects weight Previously in The Sun, experts explained how sleep is closely linked with weight. Disrupts hunger hormones Ghrelin is a hormone released after the brain signals the stomach is empty, while leptin is released from fat cells to suppress hunger - and tell the brain it's full. Studies have shown that when you don't get enough shut-eye, the body makes more ghrelin and less leptin - leaving you more hungry. One study of 12 men led by University of Chicago showed two days of sleep deprivation drove leptin levels in the blood down by 18 per cent, while increasing ghrelin by 28 per cent. The men reported a 24 per cent increase in their hunger and appetite compared to when they were given two restful nights. More time to eat The less you are asleep, the more you are awake. This gives more of an opportunity to eat. In the modern day world, people are awake for up to 17 hours at a time - 7am till 12pm. It leaves a huge window for being awake and eating. If you're struggling with both your weight and sleep, try finishing your meals three to four hours before bed time. That might mean limiting your eating window from 9am until 6pm. Reach for takeaways If you have a weird sleeping pattern, chances are your eating schedule is also off-whack. Struggling to sleep can see us turn to convenience - takeaways, ready meals, oven foods and more, whi;e being energised gives us more motivation to cook healthily. Eat more calories than normal Studies suggest that the less sleep you get, the more calorie-dense food you choose to eat. One study in Chicago found that men ate more food at a buffet after four consecutive night's of rough sleep compared with when they were rested. They consumed around 340 calories more, mostly because they ate more snacks and carbohydrate-rich food. Researchers from King's College London also found that adults consumed an additional 385 calories – the equivalent of one and a half Mars Bars – on days after they were deprived of kip by combining the results of 11 previous studies. More desire for food Foods, especially those high in calories, are more appetising when we are sleep deprived because we subconsciously know they will boost our energy. A German study showed the lengths sleepy people would go to for calorific snacks using 32 healthy men. After a normal dinner and either a restful or restless night's sleep, the men were given three Euros to spend on snacks and told to bid the maximum amount they were willing to spend on each item. When sleep deprived. participants were willing to pay extra for the junk food items - which they were allowed to eat afterwards - suggesting a stronger desire. Fat storage more likely Scientists have warned that not getting enough sleep changes how the body deals with food, which could then lead to weight gain. One study showed that men who ate a large bowl of chilli mac and cheese after four nights of bad sleep reacted differently to the food than those who were well-rested. Researchers at Pennsylvania State University said blood tests showed lipids (fats) from foods were cleared faster, suggesting they were being stored almost instantly. The process did not spring back to its normal rate even after the men were given a long night's sleep. The study also challenged previous claims that sleeping over nine hours each night is harmful. Previous research has suggested "long sleepers" could be at higher risk of stroke and heart disease. Researchers said "misclassification" may be to blame, as 21 per cent of 'long sleepers' actually slept less than six hours, suggesting that time spent in bed is often confused with actual sleep time. Prof Shengfeng Wang, senior author of the study, said: 'Our findings underscore the overlooked importance of sleep regularity. 'It's time we broaden our definition of good sleep beyond just duration.' The study team suggested that inflammation could be upping the risk of disease in people who sleep poorly, as disrupted sleep might trigger immune responses that contribute to illness. Researchers concluded: "Our results may suggest that the various dimensions of sleep traits deserve more attention in future studies and that pursuing comprehensive control of sleep traits may have greater benefit for health over merely ensuring adequate sleep duration." Fortunately, there are easy things we can do to correct some – if not all – our poor sleep habits, they suggested. "For example, the disruption of sleep rhythm can be substantially improved if the unhealthy habit of social media use before sleep (so-called Twitter jetlag) can be corrected," they said. Next, the team will look into whether sleep improvements can reduce the risk of disease over time. The best sleep routine and environment Thomas Høegh Reisenhus, TEMPUR® sleep specialist & sleep counsellor, reveals the key components of a good bedtime routine and environment... A sure-fire way to facilitate a better night's sleep is to practice good sleep hygiene. Establish a sleep routine that works for you and stick to it. This will help your body establish a consistent, natural sleep-wake cycle which can do wonders for your overall sleep quality. As such, try to avoid making up for lost sleep with a lie-in. Instead of sleeping in, spend your morning reading a book in bed or having a leisurely coffee in the kitchen. Ensure that your bedroom, bedding, and sleepwear are fit for purpose too. The ideal sleep environment is dark, quiet, and cool – much like a cave. If you find unwelcome sources of light are keeping you up, consider investing in an eye mask or black-out curtains. Adding soft furnishings can be a great way to reduce noise, with the surfaces having an absorptive quality, but if this doesn't work, consider embracing a soothing soundtrack to block it out. In terms of temperature, try to keep your bedroom at 18°C. You can further reduce the risk of waking up due to overheating by ensuring that all your bedding and sleepwear is made with natural, breathable materials such as cotton and linen. Bear in mind that everyone is different; what might work for most, may not work for you! Whilst knowing how much sleep you should get, how to overcome common barriers, and practicing good sleep hygiene can facilitate a great night's sleep, if you continue to struggle with sleep or fatigue persistently, do not hesitate to visit a doctor or health professional for support.

Major study finds link between bad habit practiced by 70million Americans and more than 170 diseases
Major study finds link between bad habit practiced by 70million Americans and more than 170 diseases

Daily Mail​

time3 days ago

  • Daily Mail​

Major study finds link between bad habit practiced by 70million Americans and more than 170 diseases

People who repeatedly suffer from poor sleeping habits could be at greater risk of more than 170 diseases, ranging from gangrene to dementia, a groundbreaking new study suggests. The research, led by teams from Peking University and the Army Medical University in China, analyzed objective sleep data from 88,460 adults who took part in a nationwide survey run by the UK Biobank platform. The participants answered over 160 questions about their sleeping habits, including their ability to fall to sleep, their hours of sleep per night, their quality of sleep and associated lifestyle and behaviors. From an in-depth analysis of the results, the researchers found significant associations between various sleep traits and 172 diseases. The included participants were on average 62 years old, and 43 percent were males. Using data from a wearable device worn over an average of about seven years, researchers identified that 92 diseases had over 20 percent of their risk attributable to poor sleep behavior. Notably, irregular bedtime, defined in the study as falling asleep after 12:30AM, was linked to a 2.6-fold higher risk of liver cirrhosis, while inconsistent sleeping patterns increased the risk of gangrene, death of body tissue, by 2.6 times. A total of 42 diseases exhibited over two-fold risk associated with certain sleep traits such as sleep quality, quantity and consistency. These conditions included Parkinson's disease, age-related frailty, gangrene, fibrosis and cirrhosis of liver. Meanwhile, 122 diseases had at least 1.5-fold risk, including type 2 diabetes, respiratory failure, bone and spine fractures and urinary incontinence. Among the 172 diseases found to be associated with sleep, up to 52 percent of the risk of a single disease could be attributed to a sleep trait. Ninety-two diseases had over a 20 percent risk attributable to at least one sleep trait, and 44 diseases had one attributable risk over 30 percent. Some common diseases showed considerable attributable risk, such as Parkinson's disease (37 percent by caused by inconsistent sleeping patterns) and urinary incontinence (24 percent by how much time you spend asleep while in bed). Importantly, the study challenges previous claims that 'long sleep' (more than nine hours) is harmful. While subjective reports have linked long sleep to stroke and heart disease, objective data in the most recent study revealed this association only with heart disease. Misclassification may be to blame, the researchers say. Just over 21 percent of 'long sleepers' actually slept less than six hours, suggesting that time spent in bed is often confused with actual sleep time. Recommended guidelines suggest seven to nine hours is the ideal sleep time for adults. 'Our findings underscore the overlooked importance of sleep regularity,' said Prof. Shengfeng Wang, senior author of the study. 'It's time we broaden our definition of good sleep beyond just duration.' Looking ahead, the researchers want to look at the impact of sleep treatment plans on chronic disease outcomes. Dr Chris Winter, a neurologist specializing in sleep, previously told the link between poor sleep and health issues are 'probably multi-factorial.' He said that sleeping too little causes the nervous system to malfunction, leading to a higher heart rate, high blood pressure, and elevated stress levels. Poor sleep can also exacerbate inflammation in the body, a well-known risk factor for cardiovascular disease, stroke, dementia, and autoimmune diseases like rheumatoid arthritis. Weight and metabolism are also impacted when a person sleeps too poorly, as diet tends to suffer. Sleep's effects on hormones mean people are likely to make unhealthier food choices. Dr Beth Frates, director of lifestyle medicine and wellness in the Department of Surgery at Massachusetts General Hospital, said: 'Most people focus on exercise and diet when it comes to weight management and a healthy heart, but few focus on sleep. 'Working to find ways to clean up sleep hygiene may help people to extend sleep time to the recommended seven to nine hours per night. 'This could, in turn, lead to consuming fewer calories and even weight loss in people who are in the overweight category by BMI.' In another study examining the risk to heart health published in the Journal of the American Heart Association, researchers found that middle-aged adults with conditions like high blood pressure, type 2 diabetes, heart disease, or stroke may face a higher risk of cancer and premature death if they sleep less than six hours a night. It is known that the effects of poor sleep can be felt immediately, and after around three days of too little sleep, a person can develop hallucinations or psychosis. It can also lead to an increased risk of death by accident or injury. Almost 20 percent of all serious car crash injuries among the general public are associated with driver sleepiness, independent of alcohol effects. Compared to drivers who had slept for a regular seven hours, those who reported they'd slept fewer were 1.3 times more likely to crash, while those who slept five to six hours were nearly two times as likely to crash.

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