First nasal spray for allergic reactions now available in UK
The Medicines and Healthcare products Regulatory Agency (MHRA) has approved the adrenaline (epinephrine) nasal spray (EURneffy) for emergency treatment.
The manufacturer, ARS Pharma, has been contacted for comment about whether it plans to seek wider approval for use on the NHS.
Julian Beach, MHRA interim executive director of healthcare quality and access, said: 'Patient safety is our top priority, which is why we're pleased to approve the first needle-free nasal spray formulation of adrenaline for the emergency treatment of anaphylaxis in the UK.
'Until now, adrenaline for self-administration has only been available via auto-injectors.
'While this represents an important new option, adrenaline auto-injectors remain a vital and potentially life-saving treatment, giving people experiencing anaphylaxis valuable time before emergency help arrives.
'We continue to encourage everyone at risk of severe allergic reactions, and those around them, to familiarise themselves with how to respond in an emergency.
'Resources and guidance are available on the MHRA website to help people be prepared.'
Anaphylaxis is a sudden and life-threatening allergic reaction that can cause a drop in blood pressure and breathing difficulties.
EURneffy is intended for use in adults and children who weigh 30kg (about 66lb) or more, and can be used even if people have colds or blocked noses.
It is a single dose nasal spray that delivers its entire contents (2mg) upon activation.
People are reminded that the plunger should not be pressed before inserting the product into the nostril, otherwise the single dose will be lost.
The MHRA said patients should always carry two nasal sprays with them in case a second dose is needed, and tell family and friends where it is.
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Reuters
an hour ago
- Reuters
Roche to test if new drug can prevent Alzheimer's disease, Bloomberg News reports
July 27 (Reuters) - Swiss drugmaker Roche Holding (ROG.S), opens new tab plans to test whether an experimental medicine can prevent Alzheimer's disease symptoms in high-risk people, Bloomberg News reported on Sunday. The new late-stage study will target people who are at risk of cognitive decline and aim to slow down the emergence of symptoms or prevent them fully, the report said, citing a statement. The new pre-clinical study is the third largest late-stage trial that the company has announced for its drug trontinemab, which uses an experimental technology called brain shuttle to ferry medicine past the protective blood-brain barrier, according to the report. Rivals like Eli Lilly (LLY.N), opens new tab have been making progress in the complicated field of Alzheimer's recently with Lilly's Alzheimer's drug Kisunla getting recommendation from the European Medicines Agency (EMA) last week. Reuters could not immediately verify the report. Roche did not immediately respond to a request for a comment. Treatments for Alzheimer's approved so far, including Eisai (4523.T), opens new tab and Biogen's (BIIB.O), opens new tab Leqembi, and Eli Lilly's Kisunla, are designed to clear sticky clumps of a protein called amyloid beta in the brain. They also carry hefty price tags and the risk of serious brain swelling and bleeding.
Telegraph
2 hours ago
- Telegraph
Grandmother died of sepsis after being misdiagnosed with stomach complaint
A grandmother died of sepsis after doctors failed to recognise signs of a urinary tract obstruction, a coroner has found. Suzanne Edwards, 71, of Leighton Buzzard, Bedfordshire, visited her GP on Nov 29 2024 with abdominal pain and vomiting but despite urgent blood and urine tests she was not sent to hospital. Later that day her symptoms worsened and she went to A&E at Milton Keynes University Hospital, Bucks. Her test results were indicative of systemic inflammation and dehydration but she was diagnosed with gastroenteritis and discharged. Her condition deteriorated further and the following day her family called NHS 111. She was directed to an urgent care centre and transferred to Bedford Hospital where clinicians identified a 7mm stone in her urinary tract and sepsis. She underwent emergency surgery but died later on the evening of Dec 1 from septic shock. 'Heart of our family' Stacey Edwards, her daughter, said: 'My mum was the heart of our family – full of warmth, compassion and humour. 'It's devastating to know that her death may have been avoided if the signs of sepsis had been recognised sooner.' Her family described her as 'an unbelievably kind and caring woman with a wicked sense of humour and fun'. She leaves behind husband Terence, two children and two granddaughters. Stacey said: 'When she visited her GP she was so unwell she used a wheelchair. 'After she was taken to A&E we were told it was likely gastroenteritis. She was given IV fluids and pain relief but she was still in pain and struggling. 'There was very little communication from doctors and when she was discharged we were simply told to come back if symptoms returned. 'At home, things got worse. But because she'd been examined by medical professionals we thought she just needed time to recover. 'The call we received later that evening asking us to come in urgently is something we'll never forget. 'Neither is watching her suffer in those final days.' Jewellery went missing Soon after her death Mrs Edwards' family realised her jewellery worth thousands of pounds – three necklaces and four bracelets – were missing. Stacey said: 'Mum never took off her jewellery. 'It is heartbreaking to think someone may have taken advantage of such a tragic situation.' Bedfordshire Hospitals NHS Foundation Trust launched a full investigation and search at the time but the items were never found. Tom Osborne, the senior coroner for Milton Keynes, recorded a narrative verdict saying there was a failure to recognise the signs of a urinary tract obstruction, leading to missed opportunities to treat Mrs Edwards before sepsis developed.
The Guardian
4 hours ago
- The Guardian
Parents, beware the devastating consequences of measles
After reading the letters about vaccine misinformation and hesitancy (Measles surge shows why vaccinations are crucial, 20 July), I felt I must write to tell you of one unrecognised cause of the drop in vaccine uptake: when I worked as a community school nursing sister in the 1980s, with 11 state schools and a number of private schools that took up the vaccine service, we had 98% uptake of vaccines in the school setting. This was due to the system of sending letters home to parents requesting their consent and following up by phone, if necessary, by the school office staff. The children came in class batches. Then the local health authority decided that this service should be discontinued and parents were invited to take their child to the local GP surgery for their vaccinations. The uptake plummeted to less than 40% of eligible children due to children not taking the letters home, or parents forgetting or losing the letter – or being unable to take time off to take their child to the surgery. When I asked the GPs at the local health centre what the uptake for the cohort of eligible children was, they looked at their records and were surprised, but reluctant to do anything about it. Health visitors were responsible for, and very successful in, advising new mothers when vaccines were due, where to get them and encouraging uptake. It should be compulsory for all vaccines for preschool children (which includes measles) to be done before a child is admitted to school, as in many other countries. As a midwife, I saw a baby born to a mother who had contact with rubella in early pregnancy. The little girl was born with a body rash, had bilateral cataracts and was totally deaf. She was was very ill. Schools for deaf children may return again for these children if vaccination is not taken up for whatever reason. How StephensLiphook, Hampshire I contracted measles just before the NHS was established. With it came serious ear infections, burst eardrums, etc. There were no vaccines, just ear drops. Over the years the infections and operations continued and now, aged 82, I have no hearing with complications. I beg people to think seriously about vaccination. The consequences of measles can sometimes be devastating. Jean JacksonSeer Green, Buckinghamshire I caught measles aged six in 1953, at a time when parents hoped their children would get it (and chicken pox and mumps) so as to gain immunity. My dad, aged 54, had not had measles as a boy, caught it from me and nearly died. The risk of not vaccinating children is not just to WallLondon
