New Covid vaccine developed by USA researchers is ready to fight Coronavirus. How effective it is?
Covid
, they present challenges like the high amount of mRNA needed to produce them and the constantly evolving nature of the pathogen.
"The virus changes, moving the goal post, and updating the vaccine takes some time," said senior author Suresh Kuchipudi, chair of Infectious Diseases and Microbiology at the University of Pittsburgh School of Public Health.
To address these challenges, the researchers created a proof-of-concept
Covid vaccine
using what's known as a "trans-amplifying" mRNA platform.
by Taboola
by Taboola
Sponsored Links
Sponsored Links
Promoted Links
Promoted Links
You May Like
Pare a neuropatia: descubra como
NeuroFit
Undo
In this approach, the mRNA is separated into two fragments -- the antigen sequence and the replicase sequence -- the latter of which can be produced in advance, saving crucial time in the event a new vaccine must be developed urgently and produced at scale.
In addition, the researchers analysed the spike-protein sequences of all known variants of the SARS-CoV-2 for commonalities, rendering what's known as a "consensus spike protein" as the basis for the vaccine's antigen.
Live Events
In mice, the vaccine induced a robust immune response against many strains of SARS-CoV-2.
"This has the potential for more lasting immunity that would not require updating, because the vaccine has the potential to provide broad protection," said Kuchipudi.
"Additionally, this format requires an mRNA dose 40 times less than conventional vaccines, so this new approach significantly reduces the overall cost of the vaccine."
The study, published in the journal npj Vaccines could inform more efficient vaccine development for other constantly evolving RNA viruses with pandemic potential, Kuchipudi said.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Time of India
19 minutes ago
- Time of India
Why Japanese food is healthier? Because their base is water, not oil: 5 other facts that make Japanese one of the healthiest cuisines
Most cuisines kick off with oil in a hot pan. Japanese cooking usually begins with water — or a light broth made from kombu (seaweed), mushrooms, or dried fish. This single shift changes everything. Instead of frying, the food is simmered, steamed, or poached. It keeps flavours clean and meals easier to digest. That's one big reason why Japanese food feels light, yet somehow satisfying. But the health benefits aren't just about skipping oil. Japanese food takes a balanced approach, where nothing is overdone. It isn't obsessed with being 'low carb' or 'sugar-free.' It just leans on smart choices, clean techniques, and tradition that has lasted because it works. Here's what else makes this one of the world's most quietly effective ways of eating: Meals are built on variety, not volume A typical Japanese meal isn't about one big main dish. It's a mix of small, simple things — some rice, a few cooked vegetables, a little grilled fish, miso soup, maybe some pickles or tofu. Nothing is heavy on its own, but together it adds up to a balanced, filling meal. You get what your body needs without feeling weighed down. It's enough, but never too much. Fermented foods are part of the everyday table Miso, soy sauce, pickles, natto — these fermented foods are just normal things people eat in Japan every day. They help with digestion, keep your stomach happy, and make it easier for your body to absorb and use the nutrients from food. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like How Much Does It Cost to Rent a Private Jet - The Prices May Surprise You! Private Jet I Search Ads Learn More Undo Instead of taking probiotics through supplements, the average Japanese meal delivers them naturally, through flavour-rich foods that have been around for centuries. Fish takes the lead over meat Japan has always leaned more towards seafood than red meat. Fish like salmon, sardines, and mackerel show up a lot in Japanese meals. They've got good fats (omega-3s) that help your heart and brain. The way they're cooked is super simple — usually just grilled, eaten raw, or lightly simmered. No heavy sauces, no extra oil, just clean, tasty fish. And they don't overdo it with huge portions either, which keeps the meal light and balanced. Vegetables are central, not a side note Japanese meals tend to include several types of vegetables, served in different ways — raw, steamed, simmered, pickled. Seaweed is also common and adds minerals you won't find in land-based greens. These aren't coated in cream or fried in batter. They're served in ways that preserve texture and nutrition. Vegetables aren't added in to 'be healthy.' They're just part of the meal, always have been. Meals are paced, not rushed Food is eaten slowly, with intention. It's served in separate bowls, eaten with chopsticks, and rarely gulped down. This naturally slows things down. You chew more, taste more, and give your body time to signal when it's full. There's no pressure to clear a huge plate. That slower way of eating really helps — not just with digestion, but with how you actually feel about the food you're eating. Japanese cuisine doesn't need to label itself as healthy. It simply is — because of the way it's cooked, the ingredients it uses, and the habits around how it's eaten. Meals built on water instead of oil, variety instead of overload, and care instead of shortcuts — that's what makes it work.
Time of India
20 minutes ago
- Time of India
India-New Zealand conclude 2nd round of FTA talks; achieve progress on trade, investment, economic cooperation
The second round of India-New Zealand Free Trade Agreement Negotiations, which concluded in New Delhi, made significant advancements in multiple areas, including trade in goods and services, investment, rules of origin, customs procedures and trade facilitation, technical barriers to trade, sanitary and phytosanitary measures, and economic cooperation. According to a release by the Ministry of Commerce & Industry, discussions were marked by mutual interest in achieving early convergence on several texts. Both sides reaffirmed their commitment to concluding a balanced, comprehensive, and forward-looking agreement. Explore courses from Top Institutes in Please select course: Select a Course Category Data Analytics Management Project Management Digital Marketing Technology Healthcare Data Science Operations Management Degree Artificial Intelligence healthcare Public Policy MCA CXO MBA Product Management others Others Design Thinking Leadership Data Science Cybersecurity Finance Skills you'll gain: Data Analysis & Visualization Predictive Analytics & Machine Learning Business Intelligence & Data-Driven Decision Making Analytics Strategy & Implementation Duration: 12 Weeks Indian School of Business Applied Business Analytics Starts on Jun 13, 2024 Get Details The Second Round of negotiations for the India-New Zealand Free Trade Agreement (FTA) concluded successfully on July 25 in New Delhi, further advancing the shared objective of strengthening bilateral trade and economic partnerships. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like ACE Nest Yamuna Expressway – Affordable Luxury Awaits Ace Noida Book Now Undo The Ministry stated that this development catalyses the shared commitment to deepen economic ties, as guided by the Prime Minister of India, Narendra Modi, during the visit of Christopher Luxon , Prime Minister of New Zealand, in March 2025. The FTA was launched during the meeting between Union Minister of Commerce and Industry, Piyush Goyal and Todd McClay, Minister for Trade and Investment, Government of New Zealand, on March 16, 2025. Live Events The Third Round of negotiations is scheduled to be held in New Zealand in September 2025. The intersessional virtual meetings will maintain the forward trajectory set in the second round. According to government data, India's bilateral merchandise trade with New Zealand reached USD 1.3 billion in FY 2024-25, recording a 48.6 per cent growth over the previous financial year, signalling the growing potential of the economic partnership. The FTA is expected to enhance trade flows, support investment linkages, promote supply chain resilience, and establish a predictable and enabling environment for businesses in both countries. Free Trade Agreements (FTAs) are treaties between two or more countries to reduce or eliminate trade barriers such as tariffs, quotas, and import restrictions on goods and services. These agreements aim to promote economic integration, increase market access, and enhance cooperation between nations.
Time of India
23 minutes ago
- Time of India
Astronomers reveal a chilling countdown to the end of the universe
For decades, scientists believed the universe would expand forever, driven endlessly outward by a mysterious force known as dark energy. But a new study has upended that view with a provocative idea: the cosmos may one day stop expanding and instead collapse in on itself in a cataclysmic event called the 'Big Crunch.' According to the research, which is currently in preprint and awaiting peer review, this reversal could happen in about 20 billion years. Based on new models and fresh astronomical data, scientists are rethinking the fate of everything we know. The universe may not expand forever The traditional model of the universe's fate was built on the assumption that dark energy is constant and positive, a force pushing galaxies apart faster over time. But researchers analysing data from the Dark Energy Survey (DES) and the Dark Energy Spectroscopic Instrument (DESI) found evidence that dark energy might not be constant after all. Instead, it could vary over time, as proposed by a new theoretical framework called the axion-dark energy (aDE) model. One of the most striking findings in the new study is the possibility that the cosmological constant — which reflects the energy density of space itself — may be negative. If true, this would mean that gravity could eventually overpower expansion. Over time, this shift would cause the universe's growth to slow, stop, and then reverse into a contraction phase. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Wonorejo: Unsold Sofas May Be at Bargain Prices (Prices May Surprise You) Sofas | Search Ads Search Now Undo What is the Big Crunch If contraction occurs, all matter and energy could eventually be compressed into a single, dense point — an event known as the Big Crunch . This would be the reverse of the Big Bang . According to the aDE model, the total lifespan of the universe would be about 33.3 billion years, and we are already 13.8 billion years into that span. That leaves approximately 20 billion years before the predicted collapse. Not a final verdict yet Although the findings are significant, scientists caution that this new model is not confirmed. It is based on observational trends and evolving theoretical physics. Further investigation using next-generation telescopes and deeper space surveys will be needed to determine whether dark energy truly changes over time and whether a cosmic collapse is on the horizon. Is the end really the end Even if the Big Crunch occurs, it might not mark the permanent end of everything. Some theories propose that a collapsing universe could eventually lead to a rebirth — a new Big Bang triggering a fresh universe cycle. While these ideas remain speculative, the study has opened a bold new chapter in understanding how — and when — our universe might end.
