Latest news with #Diseases
Al Etihad
4 days ago
- Health
- Al Etihad
Abu Dhabi Agriculture and Food Safety Authority receives global accreditation for camel disease proficiency testing
18 July 2025 12:21 ABU DHABI (ALETIHAD)Abu Dhabi Agriculture and Food Safety Authority (ADAFSA) has been awarded international accreditation (ISO/IEC 17043:2023) for proficiency testing in camel disease diagnostics, becoming the first globally accredited entity in this field. The accreditation was granted by United Kingdom Accreditation Service (UKAS) after ADAFSA met all stringent international accreditation represents global recognition of ADAFSA's competency in providing proficiency testing services, which are a fundamental tool for ensuring the quality and reliability of laboratory diagnostics for camel diseases. It enhances accuracy and efficiency standards while bridging gaps in specialised measurement programmes within this line with this achievement, Biosecurity Affairs Division at ADAFSA—internationally recognised by World Organisation for Animal Health (WOAH) as a Collaborating Centre for Camel Diseases and a Collaborating Centre for Quality Management Systems—has launched the world's first proficiency programme for evaluating laboratories' efficiency in detecting antibodies for Peste des Petits Ruminants (PPR) in camels. This programme focuses on improving validation processes for diagnostic kits used in antibody detection, supporting global efforts to combat and eradicate the initiatives reflect ADAFSA's commitment to supporting national and international laboratories in developing precise laboratory diagnostics for camel diseases, ensuring high-quality results on a global scale. This latest achievement raises the total number of global certifications obtained by ADAFSA to 15, reinforcing its leadership in food security and animal disease control, particularly camel diseases, and strengthening its scientific status as a global reference centre in this domain. Notably, ADAFSA's Collaborating Centre for Camel Diseases, established in May 2022 and recognised by WOAH, serves as an authoritative scientific body in diagnosing and studying camel diseases. It offers advanced diagnostic, research, and training services in collaboration with leading international institutions. This accreditation further cements Abu Dhabi and the UAE's position as a leading hub for animal health and biosecurity.
Mint
13-07-2025
- Health
- Mint
Endocrinologist shares 10 daily habits that increase cortisol and affect metabolism
When it comes to metabolism, many of us overlook the silent influencers in our daily routines. The truth is, everyday habits can significantly elevate cortisol levels, impacting our metabolism and overall health. Stress, in manageable doses, can propel us through life's challenges. However, chronic stress—lasting weeks or months—takes a toll on our bodies, primarily through the hormone cortisol. This hormone, released during stressful moments, triggers the liver to release more glucose into the bloodstream for quick energy. In situations of immediate danger, this response is lifesaving. However, in the modern world, where stress often stems from deadlines or financial concerns, that energy frequently goes unused. As a result, blood sugar levels rise, and the body compensates by producing more insulin, according to the Centres for Disease Control and Prevention. While this may seem harmless, persistent insulin elevation can lead to insulin resistance. This condition not only raises the risk of type 2 diabetes but is also associated with weight gain, polycystic ovary syndrome (PCOS), and fatty liver disease. Moreover, elevated cortisol levels encourage fat storage, particularly around the abdomen, known as visceral fat, which poses significant risks to cardiovascular health, as reported in the Archives of Pharmacy and Pharmaceutical Sciences. The manifestations of chronic stress infiltrate our daily habits, leading to erratic sleep patterns, heightened cravings for unhealthy foods, and skipped exercise routines. This creates a vicious cycle that perpetuates high cortisol levels and strains our metabolic system, according to the journal Diseases. Dr Vrinda Agrawal, a Consultant Endocrinologist at CARE Hospitals, highlights that managing stress is essential, not just for emotional well-being, but for efficient metabolic function. Inconsistent sleep patterns Lack of regular sleep—even if you manage just seven hours a night—can spike cortisol levels and disrupt metabolic balance. Struggling to maintain an exercise routine? Skipping physical activity contributes to higher cortisol levels and the accumulation of abdominal fat, according to the National Library of Medicine. Consuming too much caffeine, particularly late in the day, can interfere with your sleep quality, thereby further heightening stress and cortisol levels, as reported in the Journal of Clinical Sleep Medicine. Irregular eating patterns can disrupt insulin levels and glycogen storage, negatively affecting metabolism, as reported in the Reproductive Toxicology Journal. Heightened cravings for sugary or salty foods can lead to unhealthy eating habits that keep blood sugar and cortisol levels high, according to Harvard Health. Spending excessive time on screens, whether at work or during leisure time, promotes a sedentary lifestyle and negatively impacts stress levels, potentially leading to metabolic issues, as reported in the Korean Journal of Family Medicine. Neglecting to incorporate moments of calm—such as deep breathing or meditation—can help prevent stress from accumulating in your body. Failing to recognise and address chronic stress can lead to persistent high cortisol levels, affecting your weight and energy levels, according to the International Journal of Preventive Medicine. Failing to monitor your health can delay diagnoses of potential metabolic issues associated with high cortisol levels. A diet high in processed foods and low in fibre can exacerbate metabolic dysfunction, leading to weight gain, as reported in Frontiers in Endocrinology. To counter these effects, enabling consistent, health-oriented habits is crucial. Prioritise regular sleep, gentle daily physical activity, and mindful moments to help you decompress. Simple lifestyle changes can have a significant impact on regulating your metabolism and overall health, according to the American Journal of Lifestyle Medicine. By understanding these connections and taking proactive steps, you can better manage your cortisol levels and promote a healthier metabolic response to the stresses of everyday life.
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Business Standard
09-06-2025
- Health
- Business Standard
New mRNA vaccine is more effective, less costly to develop, shows study
A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a study by researchers at the University of Pittsburgh School of Public Health and the Pennsylvania State University. The study was published today in npj Vaccines. Though highly effective at inducing an immune response, current mRNA vaccines, such as those used to prevent COVID-19, present two significant challenges: the high amount of mRNA needed to produce them and the constantly evolving nature of the pathogen. "The virus changes, moving the goal post, and updating the vaccine takes some time," said senior author Suresh Kuchipudi, Ph.D., chair of Infectious Diseases and Microbiology at Pitt Public Health. To address these challenges, the researchers created a proof-of-concept COVID-19 vaccine using what's known as a "trans-amplifying" mRNA platform. In this approach, the mRNA is separated into two fragments -- the antigen sequence and the replicase sequence -- the latter of which can be produced in advance, saving crucial time in the event a new vaccine must be developed urgently and produced at scale. Additionally, the researchers analysed the spike-protein sequences of all known variants of SARS-CoV-2 for commonalities, rendering what's known as a "consensus spike protein" as the basis for the vaccine's antigen. In mice, the vaccine induced a robust immune response against many strains of SARS-CoV-2. "This has the potential for more lasting immunity that would not require updating, because the vaccine has the potential to provide broad protection," said Kuchipudi. "Additionally, this format requires an mRNA dose 40 times less than conventional vaccines, so this new approach significantly reduces the overall cost of the vaccine." The lessons learned from this study could inform more efficient vaccine development for other constantly evolving RNA viruses with pandemic potential, Kuchipudi said. "We hope to apply the principles of this lower-cost, broad-protection antigen design to pressing challenges like bird flu," added Kuchipudi.
Time of India
03-06-2025
- Health
- Time of India
New Covid vaccine developed by USA researchers is ready to fight Coronavirus. How effective it is?
Amid fresh surge in Covid-19 cases, a team of US researchers has developed a new type of mRNA vaccine that is more scalable and adaptable to tackle continuously evolving viruses such as SARS-CoV-2 and H5N1. While the currently available mRNA vaccines are highly effective at inducing an immune response against Covid , they present challenges like the high amount of mRNA needed to produce them and the constantly evolving nature of the pathogen. "The virus changes, moving the goal post, and updating the vaccine takes some time," said senior author Suresh Kuchipudi, chair of Infectious Diseases and Microbiology at the University of Pittsburgh School of Public Health. To address these challenges, the researchers created a proof-of-concept Covid vaccine using what's known as a "trans-amplifying" mRNA platform. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Pare a neuropatia: descubra como NeuroFit Undo In this approach, the mRNA is separated into two fragments -- the antigen sequence and the replicase sequence -- the latter of which can be produced in advance, saving crucial time in the event a new vaccine must be developed urgently and produced at scale. In addition, the researchers analysed the spike-protein sequences of all known variants of the SARS-CoV-2 for commonalities, rendering what's known as a "consensus spike protein" as the basis for the vaccine's antigen. Live Events In mice, the vaccine induced a robust immune response against many strains of SARS-CoV-2. "This has the potential for more lasting immunity that would not require updating, because the vaccine has the potential to provide broad protection," said Kuchipudi. "Additionally, this format requires an mRNA dose 40 times less than conventional vaccines, so this new approach significantly reduces the overall cost of the vaccine." The study, published in the journal npj Vaccines could inform more efficient vaccine development for other constantly evolving RNA viruses with pandemic potential, Kuchipudi said.
The Sun
05-05-2025
- Health
- The Sun
Deploying AI to boost early detection of lung disease
PUTRAJAYA: Malaysia is taking a bold step in the early detection of lung disease by deploying artificial intelligence (AI) software at selected public health clinics to analyse chest X-rays. The initiative seeks to curb the nation's alarmingly high rate of late-stage lung cancer diagnoses. Currently, 90% to 95% of cases are only detected at Stage 3 or 4 when treatment is far less effective and survival rates plummet. Health Minister Datuk Seri Dr Dzulkefly Ahmad said the rollout signals a fundamental shift in the national approach to lung health, anchoring it within a more integrated public health strategy targeting both communicable and non-communicable diseases. 'Instead of treating each disease in isolation, we're now focusing on the lungs as a central point of intervention – an organ that's exposed to multiple risk factors such as smoking, air pollution, occupational hazards and infections,' he said at the Health Ministry headquarters yesterday. 'This technology allows us to monitor lung health in a more comprehensive and proactive way, enabling earlier, more effective interventions before diseases progress to advanced stages.' Disease Control Division (Non-Communicable Diseases) deputy director Dr Noraryana Hassan said the AI software, once integrated with existing X-ray machines, will enhance the accuracy and speed of diagnosis. 'The system can detect abnormalities like nodules or shadowing that may escape the human eye, thus improving the likelihood of catching diseases like lung cancer at an earlier, more treatable stage,' she said. The pilot phase will see the AI technology deployed at seven public health clinics, each serving as a regional analysis hub. The clinics selected are Seberang Perai (Penang), Kok Lanas (Kelantan), Kajang (Selangor), Luyang (Sabah), Beserah (Pahang), Pendang (Kedah) and Batu 9 Cheras (Kuala Lumpur). Clinics not equipped with the software can refer X-ray images to these hubs for analysis. Each centre will also coordinate with nearby hospitals for follow-up consultations and access to advanced diagnostics such as CT scans. Noraryana said the one-off cost of installing the AI software is approximately RM10,000 per clinic, but added that its accessibility across clinic networks means it does not need to be installed at every site. The AI initiative falls under the Malaysia Lung Health Initiative 2025–2030, a national roadmap aimed at transforming how lung diseases are detected, treated and prevented. The plan targets major respiratory illnesses including lung cancer, chronic obstructive pulmonary disease, asthma and tuberculosis. It emphasises early screening, public education, integrated care and coordinated action to reduce exposure to known risk factors. Additional components include enhanced anti-smoking campaigns, stricter enforcement of the newly passed Control of Smoking Products for Public Health Act 2023 (Act 852), improved workplace safety protocols and national-level efforts to address air pollution. The initiative also aims to reduce the burden of preventable respiratory diseases by tackling root causes such as tobacco use, second-hand smoke exposure, environmental pollutants and occupational risks. Malaysia will further elevate the conversation to the global stage with plans to table a resolution on integrated lung health at the upcoming World Health Assembly in Geneva.
