
BREAKING NEWS Family of Ronnie Coleman post update on legendary bodybuilder's condition after infection in his bloodstream
On Monday, Coleman's family announced that the 61-year-old had been 'admitted to hospital' before later revealing he had suffered an 'infection in his bloodstream'.
Now, the family have taken to Instagram once again to provide the latest update to his followers and revealed that Coleman, 61, is now 'awake' and 'fully conscious'.
In a post on Friday, they wrote: 'Ronnie is currently under close medical care, and while his condition remains delicate, we're encouraged to share that he is awake, aware, and fully conscious.
'The medical team continues to work diligently to identify the source of the infection, and Ronnie is undergoing two advanced diagnostic procedures as we write this to help determine the root cause.
'This is a critical period in his recovery, and more than ever, Ronnie needs our collective strength, positivity, and prayers.
'He's always been a fighter and with all of us standing beside him, we know he will face this battle with the same courage and determination that has defined his life.
'We also want to take a moment to thank everyone for the overwhelming love and support being sent Ronnie's way. Your prayers and messages mean the world during this incredibly challenging time.
'We've heard from several of you asking how you can help Ronnie at this time. Ronnie's team is actively working on a meaningful way for fans to get involved. We'll be sharing more details very soon'.
Coleman, 61, is largely regarded as one of bodybuilding's greatest ever competitors and holds the, joint, all-time record for most Mr. Olympia titles at eight.
He's also previously won 26 International Fitness and Bodybuilding Federation (IFBB) titles and retired back in 2007 after his reign as Mr. Olympia came to an end.
Concerns over his health initially arose after he was forced to postpone a scheduled trip to the UK this week.
In an Instagram post on Sunday, Coleman wrote: 'Hey guys, I hate to break it to y'all, but I won't be able to make it out to the UK this week like I planned. Unfortunately, I had a medical emergency and had to stick around here in the U.S. for treatment.
'But don't worry… I'm in great hands, getting the best care, and I'm staying strong through it all. I'll be back and better than ever, and I can't wait to get out there and see you all real soon!'
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The Guardian
30 minutes ago
- The Guardian
Patients with ultra-rare diseases worry new FDA rules will leave them without treatment
US drug regulators have increasingly signaled a focus on faster approvals and rare diseases, but patients with ultra-rare ailments fear they are falling through the cracks, especially given challenges to conducting clinical trials. One drug, elamipretide, garnered a narrow recommendation from independent advisers for the US Food and Drug Administration (FDA), but the agency rejected the drug's application in May and recommended another potential pathway for approval. Patients and advocates worry about new rules on who may receive the medication during this process, and whether the drug will reach approval before the pharmaceutical company runs out of funding for it. It underscores the challenges of making progress on rare and ultra-rare diseases while also making sure treatments are safe and effective. Hope Filchak is a sassy four-and-a-half-year-old who loves swimming in the lakes and pools near her home in Gainesville, Georgia. She's also deaf and blind, with some functional vision in one eye and hearing with an aid in one ear. Hope was born with an extremely rare mitochondrial condition called MLS syndrome, of which there were only 64 documented cases in the US as of 2018. MLS syndrome, for Hope, causes a potentially life-threatening heart condition called cardiomyopathy, which can make her heart pump blood less efficiently. In February 2024, she started sleeping about 17 hours a day, and her speech began regressing. An echocardiogram revealed that Hope's heart function had dropped about 14 percentage points, into potentially hazardous territory. She then started taking elamipretide, an investigational drug for mitochondrial conditions. 'Pretty soon, honestly, she had a lot more energy,' her mother, Caroline Filchak, said. Most importantly, her heart stabilized. Hope's aunt, Anna Bower, said her niece's 'quality of life dramatically improved' and soon after, she was 'running, dancing, and playing' like any other child her age. First developed in 2004, elamipretide has a long history. Advocates for patients with Barth syndrome – another mitochondrial condition with about 150 known patients – asked Stealth BioTherapeutics to pick up the drug in 2014 and shepherd it through the regulatory process. Stealth submitted its first application to the FDA in 2019, and then it went through four different review divisions at the agency. In an October 2024 meeting of the FDA's cardiovascular and renal drugs advisory committee, patients and physicians spoke about the positive effects of the drug, and the advisers eventually voted 10-6 to recommend it. 'Patients and families saw the [advisory committee's] endorsement as an encouraging sign because the FDA almost always follows its recommendation,' Bower said in June. 'But last month, it didn't.' The FDA rejected the application in May. Internal FDA reviewers noted that the drug had not met its endpoint in phase 2 trials of 12 study participants. 'We don't feel like they looked at a totality of evidence where the patient's voice was heard in the decision,' Caroline Filchak said, who added that it's been difficult to measure the effectiveness of the drug because of how rare the disease is. The FDA did offer a new pathway to approval, Stealth said in a press release. That process takes at least eight months, though it can also take years. Stealth laid off 30% of its staff after the rejection. Advocates such as Filchak are worried the company will not be able to continue pursuing approval. 'If [the FDA] drag their feet like they have throughout this entire process, Stealth is not going to be able to continue operations,' she said. Under the new pathway, the medication is not available for infants. Stealth has said that 35 patients around the world are receiving the medication, and two-thirds of them are very sick infants. In a congressional hearing in late June, the Republican representative Earl L 'Buddy' Carter of Georgia asked Robert F Kennedy Jr, the secretary of the US Department of Health and Human Services, about treatments for rare mitochondrial conditions. Carter mentioned two young constituents with these conditions, including Hope Filchak. The children 'need your help in accessing life-saving medications', Carter said, promising to follow up with Kennedy after the hearing. For now, Hope has a three-month supply of the drug. 'For children like Hope, there are no other options,' Bower said. There are no FDA-approved medications like elamipretide, and there are no similar drugs in late-stage development. Caroline Filchak said that this administration 'does have a stated commitment to accelerating therapies for rare diseases. And it seems like this recent decision by the FDA doesn't align with that commitment.' Marty Makary, the FDA's commissioner, recently announced plans to accelerate approval for select drugs and companies. He has also floated the use of machine learning, often called AI, to review applications quickly. But there are already four ways for the FDA to expedite the review of new medications, and the approval speed is not the sticking point for drugs such as these, Filchak said. Elamipretide is an example of the difficulty of developing drugs for ultra-rare conditions – and for approving them based on clinical evidence, said Holly Fernandez Lynch, bioethicist at the University of Pennsylvania Perelman School of Medicine. 'It's not the poster child of FDA efficiency,' Fernandez Lynch said, noting the long time span and the four different review divisions at FDA. 'But it's also not the poster child of 'Oh my God, we have a drug that works amazingly well, and FDA is standing in the way, and why won't they just use their regulatory flexibility?'' The drug hasn't been approved yet because it hasn't met a pre-specified endpoint, Fernandez Lynch added: 'If the evidence doesn't support approval, if the systematic evidence collection doesn't show benefit, then FDA really can't approve it.' The biotech company is now resubmitting data on knee strength improvement as part of its new application. 'Of course, these patients have a need. Of course, they have an altered tolerance for risk and altered tolerance for uncertainty,' said Fernandez Lynch. 'That's the really devastating part of all of this. And it's really heartbreaking, but it does not mean the FDA should grant approval to a product that hasn't been demonstrated effective, because we really don't know that it works.' Approving a medication without this evidence could lead to issues developing other drugs for the same conditions, Fernandez Lynch said. 'People say, 'Well, what's the big deal? These patients have nothing. Just let them try it.' I get that. If I was that mom, I would do the same thing, right? But the FDA has to make judgments for the population,' she said. For Caroline Filchak, who works for a petroleum delivery company, she plans to continue advocating for her daughter and other affected children – and has even gotten the whole family involved. 'You don't, when you think about having a kid, think that you're going to be doing this, but you do what you've got to do for your kids,' she said, noting that she and her husband, Ben, took their seven-year-old son, Thomas, to the October meeting. 'We call him our baby advocate. Ever since that meeting, every night when he would say his prayers, he would pray that the FDA says 'yes'.'


Daily Mail
an hour ago
- Daily Mail
Sami Sheen grabs some food in LA after revealing plans to remove breast implants
Sami Sheen enjoyed some refreshment at an Erewhon market in Calabasas, California, on Friday. The 21-year-old daughter of Denise Richards and Charlie Sheen was spotted leaving the market with a container of food. Two weeks ago the OnlyFans star revealed she plans to have her breast implants removed less than two years after she got them. She wrote that she's 'been experiencing health issues for nearly 2 years' with 'the weirdest symptoms.' Sami said that she 'finally discovered that I have breast implant illness,' adding, 'idk how I [hadn't] figured this out sooner but I'm so happy to finally have an answer.' She told her 202,000 followers: 'I'm hoping to get them removed asap so I can start feeling better.' And she asked: 'Pls lmk if you know of any good explant surgeons near LA.' Looking back at a picture of her pre-cosmetic surgery figure, Sami said; 'It's definitely gonna be hard going back to this size. not only physically, but mentally.' She lamented: 'I don't want to at all but i know i'll feel so much better once they are out. so i guess it's worth it.' She told fans: 'I posted about this on my TikTok but figured i would talk about it on here in case anyone else is experiencing the same thing. this is your sign to always put your health first!!!' The reality television star also noted that her sickness has affected her hair, writing in parentheses: 'Also I can't believe this is all my real hair, another thing that these implants took from me.' Someone asked Sheen what her symptoms are, which she detailed in a list. Chronic fatigue, headaches, acne, memory loss, brain fog, vertigo, joint pain, dry eyes, and mood swings were just some of the uncomfortable effects. Also listed were hair loss, allergies, skin rashes, severe anxiety, and sensitivity to temperature. Sami shared: 'BII often mimics certain autoimmune diseases, but I'm certain it's my implants because these symptoms started almost immediately after getting them done.' The influencer said she experiences 'nearly all of these symptoms every single day' and that 'it's exhausting'. The list goes on: Also listed were hair loss, allergies, skin rashes, severe anxiety, and sensitivity to temperature As recently as April, Sami said on TikTok that she planned to get another, larger boob job. She said at the time: 'They're finally fully dropped and settled in. I feel like I could've gone bigger and I really wish I went bigger. When the time comes to get them redone I'm definitely going bigger.' The star initially went under the knife in 2023 at age 19. 'I think I'm gonna go over the muscle so they look a little bit more natural,' she shared at the time.


Daily Mail
4 hours ago
- Daily Mail
EXCLUSIVE 'I fell from a balcony during lads' holiday in Ayia Napa and I've been in hospital in agony for weeks, with nightmares every night and I can't walk. I was an idiot - this is my warning to others'
A holidaymaker who fell from his balcony while on a lads holiday to Ayia Napa has warned other tourists to be prepared for the worst. Sam Hudson, 24, had been partying with his brother and a pal at the resort town when he tumbled from the second floor of his hotel while drunk. The single dad said he is 'absolutely kicking myself' at not taking out travel insurance because of the hefty hospital bill he has been left with as doctors have been desperately trying to mend his broken back, pelvis and leg. 'I know I was an idiot,' he told MailOnline. But the decorator from Lincoln said that wouldn't have even made a difference as he had drunk more than four pints and would not be covered. 'It's just not something you'd think about', he explained. He also advised all travellers make sure they had a Global Health Insurance Card before jetting off. Mr Hudson, who has a two-year-old son, left a pool party alone on June 15 when a passerby spotted him trying to walk between balconies at the Anmaria Beach Hotel, where he was staying. It is believed he was trying to reach his brother's room - which was next door - but Mr Hudson says he can't remember anything before the fall. 'I don't even remember falling, it's just a blur. I haven't got a clue to be honest why I was walking between balconies, I'd never done something like that before. 'Apparently I went to another hospital before this one but I don't remember that either. 'Its scary that I can't remember anything but I would get awful nightmares at the beginning. 'My first memory is being on all these machines but I've tried to block out all that stuff because I was in so much pain.' The passerby phoned the emergency services when they saw Mr Hudson plunge from the balcony. He was then rushed to a local clinic, Famagusta hospital in Paralimni, before being transferred to the biggest hospital on the island, Nicosia General Hospital. Doctors said at the time Mr Hudson, who was in 'unimaginable pain', was 'lucky to be alive'. They operated on his pelvis a week ago. 'It's been getting better since the operation, I can finally get up and I spent an hour in the wheelchair today, but I'm still in absolute agony which is to be expected since I've been laying down for so long,' Mr Hudson said. 'I've been going stir crazy, there's only so many things you can watch on Netflix. I zone out now I hardly even watch it anymore. 'I also miss my son so much, I FaceTime him a couple times a day but he's too little to understand why I'm not there. I hope I can see him when I leave hospital.' He said he didn't regret going on this trip but wished others would not have to go through what he has had to go through. 'I will not be going on another lad's holiday though,' he said and revealed that he will only stay in rooms on the ground floor. 'I'm definitely scared of heights now.' His brother, Nathan, and their friend only discovered the terrifying accident when they returned to the hotel where they were met by police waiting in the lobby. Mr Hudson's stepmother, Karen, and her husband flew out the next day to be with their son and have had to fly back and forth while trying to manage their business. 'You just go totally numb, it was the worst phone call you could get. Your mind goes straight for the worst,' Mrs Hudson told MailOnline. The 'devastated' family have set up a GoFundMe to cover health costs after they were faced with paying for a repatriation plane - which costs around £16,000 - or staying in Cyprus for the duration of Mr Hudson's recovery. Nathan is said to be in shock after seeing his brother in hospital and was unable to eat or sleep immediately after the accident. Ms Hudson said: 'You know what young boys are like but I never could have predicted something like this would happen. 'Doctors at the hospital have said he's lucky to be alive or to not have more severe damage. 'Even though the balcony is second floor, the hotel is on a slope and there's a restaurant too, so it's more like the fourth floor. 'If the passerby hadn't seen him, Sam could have been lying there for much longer because their room was at the back of the hotel. She added: 'We told him so many times before he left that he needed to get travel insurance but he didn't listen. 'I want the government to make it a legal requirement that all young people must have travel insurance before travelling because I don't another family to have to go through what we have. 'I've heard of families having to remortgage their house or sell their car to cover costs of accidents like this - all because they didn't think to take out insurance.' The cops have launched an investigation into the circumstances.