
The cancer drugs that could lower the risk of Alzheimer's disease
Researchers screened over 1,300 candidate drugs, narrowing them down to five that showed potential for reducing Alzheimer's risk in human patients, including two cancer drugs.
The selected drugs, letrozole (for breast cancer) and irinotecan (for colon and lung cancer), were tested on mice and appeared to improve memory and brain function.
This finding is significant because developing new drugs for Alzheimer's is extremely costly and time-consuming, whereas repurposing existing ones could accelerate clinical trials.
The study, published in the medical journal Cell, offers a promising new direction for treatment given that Alzheimer's affects millions and care costs are projected to rise substantially.
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Daily Mail
43 minutes ago
- Daily Mail
California woman, 18, is disfigured in freak accident involving s'mores on a tabletop firepit
A California woman's been left disfigured after flames 'exploded' in her face while making s'mores over an outdoor firepit. Viana Poggi, 18, was enjoying a fun summer night on July 6 with her cousin Alaina Arbiso when chaos unfolded before their eyes. While using a cement tabletop firepit, flames suddenly blew toward Poggi, leaving her with blistering burns on her face and arms. Her cousin Arbiso said all she could remember was how fast everything happened in that terrifying moment, before she pushed her relative into a nearby pool. Arbiso said: 'Within, like, a millisecond, you don't even see it coming - you have no time to react. It just happened.' After pushing Poggi into the water, Arbiso then grabbed a hose and sprayed down the flames spreading on the table. Another family member was also hit by the dangerous flames, but only Poggi was severely injured. When she got to a local burns center, staff asked Poggi about what was used to fuel the firepit. Poggi said: 'Even when I got to the ER, I just said I got hit by fire, and they asked me, "Was it rubbing alcohol?" Because it's so common for people to be burned that way.' A friend of hers Alexandra Welsh, who's a trauma nurse in the emergency room, was shocked after seeing someone she knew arrive with such intense injuries. Welsh said: 'I work at a trauma center, so I see a lot of traumatic injuries come in, but it is so different when it is someone who you think of as a little sister.' Despite the freak accident impacting her life, Poggi, who's been left with scars and burn marks, decided to make the best of it. She documented her recovery on TikTok, where she showed herself wearing a hospital gown when she was still covered in bandages. Poggi said: 'I always remember it could have been worse. I try to keep a good attitude.' The teen's due to start college soon at the University of San Francisco but, because of the burns, she's also preparing for several procedures to help with her recover. A GoFundMe page was set up by Arbiso to help her cousin with medical expenses while she embarked on the next chapter of her life. Arbiso wrote about Poggi: 'With the big move coming, multiple reconstruction surgeries, and a long emotional/physical recovery in her foreseeable future, [she's] going to need all the help she can get.' Poggi hoped that her unfortunate experience would make other people think twice before they used specific types of firepits. She said: 'I really want people to know the danger of using an alcohol-fueled pit because they are so common. We owned, I think, three of them.' There were several types of tabletop alcohol-fueled firepit available to buy online and in stores. Some were fueled by gel fuel, wood, wood pellets, and propane. Last year, multiple types of the vessel were recalled by the U.S. Consumer Product Safety Commission. The recall on the popular brand Colsen's pits warned that 'alcohol flames can be invisible and lead to flame jetting when refilling the firepit reservoir'.


BBC News
43 minutes ago
- BBC News
Somerset man commended in Parliament for Alzheimer's charity work
An 86-year-old man has been recognised in Parliament for his dedication to charity work. Brian Standring, who lives in Wellington, Somerset, recently completed his fourth skydive to raise funds for the Alzheimer's Society following his close friend's diagnosis in name was put forward for recognition in the House of Commons by his local MP Gideon Amos, who commended his efforts as a "marvellous achievement".While there, Mr Standring raised a discussion on how Parliament may be able to better support dementia and Alzheimer's diagnoses, social care and treatments. During the trip, he was presented with a printed copy of an Early Day Motion tabled in his honour, recognising his years of voluntary service and recent aerial fundraising feat."It just left me speechless," Mr Standring told BBC Radio Somerset. "It's such a great gift which I appreciated so very much." Mr Standring has spent much of the past decade supporting people with Alzheimer's, as well as raising awareness of has earned awards for his work with the organisation, sat on its volunteer advisory panel and helped organise fundraising efforts at his home."Around one million people in the UK live with dementia. It is the UK's leading cause of death and the economic impact of dementia is profound," he said."One of the main reasons for my visit and meeting with Gideon... was to explore whether and how he may be able to support the importance of dementia, locally, and at Westminster nationally."


Reuters
2 hours ago
- Reuters
US health officials, tech executives to launch data-sharing plan, Bloomberg News reports
July 26 (Reuters) - Top Trump administration health officials are expected to bring tech companies to the White House this week to roll out a plan to encourage more seamless sharing of health-care data, Bloomberg News reported on Saturday. Health and Human Services Secretary Robert F. Kennedy Jr. and Centers for Medicare and Medicaid Services Administrator Mehmet Oz are expected to host executives at an event on Wednesday, Bloomberg News reported, citing people familiar with the matter. The initiative was led by Amy Gleason, acting administrator of DOGE, known as Department of Government Efficiency, and Arda Kara, a senior adviser at CMS, the report said. Reuters could not immediately verify the report.