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Rare but ‘catastrophic' bacterial infection behind NSW children's deaths

Rare but ‘catastrophic' bacterial infection behind NSW children's deaths

A rare but highly aggressive infection that surged after the lifting of COVID restrictions probably contributed to the death of two-year-old Pippa White, as well as resulting in the deaths of at least four more children in NSW, an inquest has heard.
Associate Professor Kathryn Browning Carmo, acting director of the NSW Newborn & paediatric Emergency Transport Service (NETS), told an inquest into Pippa's death on Tuesday that hers was one of the first 'in a series of cases' of Group A streptococcus (iGAS) the emergency service dealt with over a two-year period.
Carmo said NSW was largely 'immune naive' to what appeared to be a more aggressive form of the bacteria Streptococcus pyogenes when doctors at Orange Base Hospital called for NETS assistance around 6am on June 13, 2022, hours before Pippa's death.
The infection was rare but could lead to 'devastating, crashing and catastrophic' cases of sepsis in children, Carmo said, noting that some children could go from having very little water in the lungs to 'complete whiteout' on scans 'within hours'.
'It was that aggressive … it was an absolutely devastating illness,' she said.
An academic paper co-authored by Carmo and read in court showed the NETS team were referred to 77 cases of children with iGAS between November 2022 and February 2024. Four died from the infection.
In the previous five years, they had responded to just nine cases.
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