
Organoid Intelligence: The Biocomputing Breakthrough in the Tech World
Wait, what exactly is Organoid Intelligence?
Organoid Intelligence (OI) is the idea of using living brain cells grown from human stem cells to create miniature, functional brain-like systems. These are called brain organoids. Think of them as tiny, simplified brain models not capable of thought or consciousness but able to process information, learn and even respond to stimuli. These organoids are grown in the lab and connected to computers using special electrodes, allowing them to interact with digital systems. Scientists are already teaching them to play games. Not kidding, little blobs of neurons in a dish can now learn from feedback and adjust their actions. Wild, right?
Why should we care?
Because this changes everything we know about computing. Our traditional computers even today's most powerful AI models are limited by silicon, energy and architecture. The human brain by comparison is a masterpiece of efficiency. It runs on 20 watts and can outperform supercomputers in certain tasks like pattern recognition or creativity.
Organoid intelligence could offer:
Higher learning efficiency
Extreme low-power processing
New ways to model human diseases
Bio-computing platforms that adapt like real brains
In short, we might be entering an age where biology becomes a part of our computing toolkit.
What can Organoids actually do?
Right now, they are still in their baby steps. But even these early abilities are impressive:
Learning basic game mechanics
Responding to electrical stimulation
Mimicking neural activity of human brains
Modelling diseases like Alzheimer's or epilepsy
While they can't yet write code or run simulations, researchers believe that one day they might assist with complex decision-making, adaptive learning or even act as bio-hybrids in AI systems.
Brain cells vs. Silicon chips
Here is the kicker neurons in your brain form billions of connections called synapses. These are not just data highways they change, adapt and remember based on experience. That's what gives biological intelligence its edge plasticity. Silicon chips, on the other hand, do not adapt unless you reprogram them. Even the best AI models need massive training data and power to learn. A small organoid might learn faster with less data using much less energy. And as we struggle with the limits of Moore's Law and growing energy demands of AI training, that's a game-changer.
Ethics: The brainy elephant in the room
Of course, when we start mixing biology with machines we walk into tricky territory. These are human-derived cells. While organoids are not conscious or self-aware, it is still unsettling to think of "training" brain tissue. So, ethical questions arise:
Could an organoid ever feel pain?
Should we give rights to living systems trained for computation?
Where do we draw the line between experiment and exploitation?
Right now, researchers are working closely with ethicists to create safe, humane and respectful guidelines. The focus is on scientific curiosity, medical progress and computing innovation.
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New Indian Express
a day ago
- New Indian Express
Organoid Intelligence: The Biocomputing Breakthrough in the Tech World
By now, most of us have accepted that artificial intelligence is here to stay. It is in our phones, cars and even in our fridges. But just when we thought silicon-based AI was the final frontier, something mind-blowing is emerging from the world of biology which is Organoid Intelligence. Yes, that's right not artificial intelligence but living intelligence grown in labs, using actual brain cells. It sounds like something straight out of a sci-fi movie but it is happening and if you are in tech, you would be wise to pay attention. Because the next big leap in computing power might not come from a chip but from a petri dish. Wait, what exactly is Organoid Intelligence? Organoid Intelligence (OI) is the idea of using living brain cells grown from human stem cells to create miniature, functional brain-like systems. These are called brain organoids. Think of them as tiny, simplified brain models not capable of thought or consciousness but able to process information, learn and even respond to stimuli. These organoids are grown in the lab and connected to computers using special electrodes, allowing them to interact with digital systems. Scientists are already teaching them to play games. Not kidding, little blobs of neurons in a dish can now learn from feedback and adjust their actions. Wild, right? Why should we care? Because this changes everything we know about computing. Our traditional computers even today's most powerful AI models are limited by silicon, energy and architecture. The human brain by comparison is a masterpiece of efficiency. It runs on 20 watts and can outperform supercomputers in certain tasks like pattern recognition or creativity. Organoid intelligence could offer: Higher learning efficiency Extreme low-power processing New ways to model human diseases Bio-computing platforms that adapt like real brains In short, we might be entering an age where biology becomes a part of our computing toolkit. What can Organoids actually do? Right now, they are still in their baby steps. But even these early abilities are impressive: Learning basic game mechanics Responding to electrical stimulation Mimicking neural activity of human brains Modelling diseases like Alzheimer's or epilepsy While they can't yet write code or run simulations, researchers believe that one day they might assist with complex decision-making, adaptive learning or even act as bio-hybrids in AI systems. Brain cells vs. Silicon chips Here is the kicker neurons in your brain form billions of connections called synapses. These are not just data highways they change, adapt and remember based on experience. That's what gives biological intelligence its edge plasticity. Silicon chips, on the other hand, do not adapt unless you reprogram them. Even the best AI models need massive training data and power to learn. A small organoid might learn faster with less data using much less energy. And as we struggle with the limits of Moore's Law and growing energy demands of AI training, that's a game-changer. Ethics: The brainy elephant in the room Of course, when we start mixing biology with machines we walk into tricky territory. These are human-derived cells. While organoids are not conscious or self-aware, it is still unsettling to think of "training" brain tissue. So, ethical questions arise: Could an organoid ever feel pain? Should we give rights to living systems trained for computation? Where do we draw the line between experiment and exploitation? Right now, researchers are working closely with ethicists to create safe, humane and respectful guidelines. The focus is on scientific curiosity, medical progress and computing innovation.


India Today
2 days ago
- India Today
Can a simple diet change reduce chances of dementia, Alzheimer's disease?
Is the food on your plate the secret to a sharper mind after 60? A growing body of research says yes, and a recent study published in the Journal of Nutrition, Health and Ageing offers some of the strongest evidence study, conducted by researchers at Yonsei University, South Korea, tracked over 1,31,000 adults aged 40 to 69 over a span of thirteen and a half years, investigating how four well-established dietary patterns impacted their risk of developing findings were clear: following diets rich in whole foods, leafy greens, and healthy fats, especially the MIND diet, significantly reduced the risk of dementia by up to 28%. WHAT IS THE MIND DIET?The MIND diet, short for Mediterranean-DASH Intervention for Neurodegenerative Delay, is a hybrid of the Mediterranean diet and the DASH diet (Dietary Approaches to Stop Hypertension). But it goes a step further by targeting nutrients specifically linked to brain health and cognitive brain-boosting components of the MIND diet include:Flavonoids and polyphenols from fruits, vegetables, tea, and dark chocolateFolate from leafy greens and legumesOmega-3 fatty acids from oily fish, seeds, and nutsCompared to general healthy eating guidelines, the MIND diet places special emphasis on daily consumption of green leafy vegetables and weekly servings of berries and fish foods known to nourish neurons and reduce brain HIGHLIGHTS: MIND DIET STANDS OUTResearchers scored participants' diets using four systems: Mediterranean Diet Adherence Screener (MEDAS), MIND Diet Score, Recommended Food Score (RFS), and the Alternative Healthy Eating Index (AHEI)The MIND and RFS diets showed the strongest associations with lower dementia risk, while a higher score on the Energy-adjusted Dietary Inflammatory Index (EDII), which reflects diets high in processed and inflammatory foods, was linked to a 30% higher risk of dementia.'The associations between dietary patterns and dementia were stronger in older adults and women, and varied by obesity status, highlighting how diet affects different populations differently,' the researchers AS PREVENTION, NOT JUST NUTRITIONThis study reinforces findings from earlier research. For instance, a previous trial of 906 older adults found that those with higher MIND diet scores experienced slower cognitive decline over nearly five autopsy-based study of 581 participants revealed that those who had followed the MIND or Mediterranean diet had fewer amyloid plaques in their brains, a biological hallmark of Alzheimer's both studies, higher intake of leafy greens was the most protective dietary CURE, BUT PREVENTION IS POWERFULWith no definitive cure for dementia, researchers stress the urgency of prevention-focused interventions, particularly findings underscore the potential of dietary interventions as modifiable factors to reduce the risk of dementia, especially in vulnerable populations,' the authors also noted that unlike earlier studies, this research compared multiple dietary patterns and followed participants for more than a decade, providing robust, long-term WHAT SHOULD YOU EAT TO PROTECT YOUR BRAIN?To follow the MIND diet, here's a simple roadmap:Eat more of:Leafy greens (daily)Berries (more than two days per week)Whole grainsNuts and seedsLegumesFish (once a week)Poultry (at least twice a week)Olive oil as main cooking fatLimit these foods:Red and processed meatsButter and stick margarineCheesePastries and sweetsFried and fast foodsWith science uncovering more about the links between food and brain health, one thing is becoming clear: what's good for your heart is often good for your no single diet guarantees immunity from cognitive decline, the MIND diet could be practical, sustainable with strong evidence to nourish your brain.- Ends


Hindustan Times
3 days ago
- Hindustan Times
Hepatologist explains how gut influences memory, mood and mental wellbeing; unpacks why gut may be the ‘second brain'
Several cognitive functions, such as memory, thinking, and concentration, don't just stem from brain activity alone; they are also deeply influenced by gut health. This further demonstrates the importance of gut health in maintaining overall well-being, as it has the ability to influence major functions, including immunity and mental performance. In an interview with HT Lifestyle, Dr Amey Sonavane, consultant hepatology, AHNM, explained how key brain functions are connected to gut health. From memory to concentration, much of the cognitive functions are influenced by gut health. (Shutterstock) ALSO READ: Gastroenterologist shares what your stool's colour, consistency, and frequency tell about your gut health He said, 'Memory and brain function are also closely linked to gut health. The gut sends signals to the brain that affect focus, memory, and even decision-making. When gut bacteria are in poor shape, they can produce chemicals that travel through the bloodstream to the brain, potentially increasing inflammation and contributing to cognitive decline. Some early studies suggest that changes in gut bacteria may appear even before signs of memory loss or Alzheimer's disease show up. This makes the gut an important area to watch, not just for digestion, but for long-term brain health.' Let's take a closer look at the gut-brain axis and explore the fundamentals of this connection, from the microbiome and the chemicals that make the gut the 'second brain' to how your diet can help support this bi-directional relationship. Role of microbiome The microbiome is one of the vital factors at play that form the bedrock of the gut-brain axis, shaping and influencing major cognitive functions and mood regulation. While the gut-brain axis may seem complex, the gut microbiome holds the answers and simplifies it. Dr Amey spoke about the role of microbiome and explained, 'Over the past few years, scientists have discovered something quite remarkable - your gut does a lot more than digest food. Inside your digestive system lives a massive population of bacteria and other tiny organisms, collectively called the gut microbiome. These microorganisms affect how you feel, how your body handles food, and even how your brain works. In simple terms, your gut could be quietly shaping your mood, metabolism, and memory every single day.' Gut is the second brain for mood The roots of your happy moods may be in your gut.(Shutterstock) While cognitive functions like memory, concentration, attention, decision-making, and processing are shaped by gut health, even emotions can be influenced by what's going on in your gut. It signifies the powerful role of gut health, influencing both mind and mood. Dr Amey shed light on the connection to mood regulation and said, 'The gut and the brain are constantly in touch with each other through a network known as the gut-brain axis. In fact, the gut is often called the 'second brain' because it produces many of the same chemicals that your brain does.' 'For example, about 90 percent of your body's serotonin, a chemical that influences mood, is made in the gut. It regulates things like gut motility, secretion, and blood clotting. If the balance of bacteria in your gut is disturbed, it can trigger low moods, anxiety, or even depression. New research shows that improving gut health can actually help some people feel mentally better, giving rise to what are now being called 'psychobiotics', probiotics that support mental health,' he added. Brain-friendly foods Curd in Indian dishes like raita contains good bacteria that help to balance the oral microbiome. (Shutterstock) If the role of gut health in mental wellbeing feels intimidating because it's something that is beyond your conscious control and awareness, but it turns out you can actively take charge and consciously support this gut-brain axis by adding gut-healthy food to your diet. The hepatologist shared some gut-healthy foods and warned against one common habit. Dr Amey suggested, 'Traditional Indian diets actually offer a natural advantage. Fermented foods like curd, buttermilk, dosa, and idli are full of beneficial bacteria. Fruits, vegetables, whole grains, and lentils feed the good microbes in your gut and help keep harmful ones in check. On the other hand, overuse of antibiotics, low-fibre diets, stress, and lack of physical activity can damage the microbiome.' Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.