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Driving safer workplaces: ASSP launches innovative Safety Trekr AI

Driving safer workplaces: ASSP launches innovative Safety Trekr AI

Hamilton Spectator18 hours ago
Park Ridge, Illinois, July 01, 2025 (GLOBE NEWSWIRE) — The American Society of Safety Professionals has launched ASSP Safety Trekr AI, a groundbreaking artificial intelligence-powered search tool designed to fundamentally change how safety professionals access critical workplace safety and health guidance. This innovative solution will accelerate and enhance the work of safety professionals, ultimately reducing the risk of on-the-job injuries, illnesses and fatalities. It also removes communication barriers by engaging safety professionals across multiple languages.
Safety Trekr AI is an expertly engineered online tool that leverages AI capabilities to rapidly and effortlessly navigate the vast knowledge contained within the Society's 'Safety Professionals Handbook, Third Edition.' The comprehensive reference guide is a leading go-to resource for environmental health and safety professionals and students. Several universities use it as a classroom text, showcasing safety research, case studies and practical applications from more than 90 industry experts.
Safety Trekr AI instantly scans and synthesizes the 1,330-page handbook to answer questions and provide precise safety guidance that is based on trusted data and real-world experiences. What once took considerable time through traditional search methods is now available in moments, enabling faster decision-making and more efficient compliance with workplace safety standards. The advanced tool is easily accessible from mobile devices, supporting safety professionals wherever their work takes them.
'While safety professionals can still choose to review specific sections of the handbook, it's now possible to get immediate and trusted guidance when time is of the essence,' said ASSP President Linda Tapp, CSP, ALCM, CPTD. 'In today's dynamic work environments, Safety Trekr AI empowers safety professionals to perform their jobs with unprecedented speed and effectiveness.'
Safety Trekr AI covers essential topics like regulatory guidance and risk management, summarizing information into checklists while dissolving language barriers by translating content.
'It's truly remarkable how this sophisticated tool leverages natural language processing techniques to comprehend a question and communicate the answer in the user's native language,' Tapp said. 'When obstacles are removed, work environments everywhere can be improved, fostering a truly global culture of safety.'
Unlike open AI platforms, Safety Trekr AI is a closed model, ensuring complete accuracy, credibility and transparency by only accessing trusted sources within the handbook and referencing them.
Safety Trekr AI will be demonstrated in the ASSP Marketplace at the
Safety 2025 Professional Development Conference and Exposition
from July 22-24 at the Orange County Convention Center in Orlando, FL. There will be a related Tech Talk on the expo floor. Details are available in the Safety 2025 mobile app.
The 'Safety Professionals Handbook' and the Safety Trekr AI tool can be found in the
online ASSP Store
.
About ASSP – Working together for a safer, stronger future
Since 1911, the American Society of Safety Professionals has helped occupational safety and health professionals protect people, property and the environment. The nonprofit society is based in Chicago's suburbs. Its global membership of over 35,000 professionals develops safety and health management systems that prevent injuries, illnesses and fatalities. ASSP advances its members and the safety profession by providing member communities, serving as a trusted advisor, and elevating safety through workforce development. Its flagship journal, Professional Safety, is a longtime leader in the field. Visit
www.assp.org
and find us on
Facebook
,
LinkedIn
and
YouTube
.
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Household Refrigerators And Freezers Market Is Poised To Reach Valuation Of US$ 147.45 Billion by 2033
Household Refrigerators And Freezers Market Is Poised To Reach Valuation Of US$ 147.45 Billion by 2033

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Household Refrigerators And Freezers Market Is Poised To Reach Valuation Of US$ 147.45 Billion by 2033

The household refrigerators and freezers market holds significant growth potential driven by energy-efficient technologies, rising urbanization, premiumization trends, and increasing demand in developing regions, supported by innovative financing, and evolving consumer preferences globally. Chicago, July 02, 2025 (GLOBE NEWSWIRE) -- The global household refrigerators and freezers market was valued at US$ 101.82 billion in 20224 and is expected to reach US$ 147.45 billion by 2033, growing at a CAGR of 4.20% during the forecast period 2025–2033. The household refrigerators and freezers market is experiencing a sweeping realignment as regulators from California to South Korea tighten minimum energy-performance thresholds, compelling manufacturers to rethink compressor platforms, insulation foams, and algorithmic temperature control. In 2024 the United States Department of Energy introduced test-procedure revisions that add low-load conditions, while the European Union's shift to Energy Label Class 'C' has effectively pushed R-134a units out of mainstream retail. Chinese Tier-1 OEMs such as Haier, Midea, and Hisense have therefore accelerated variable-speed inverter roll-outs, moving from legacy single-speed models to high-efficiency dual-evaporator flagships. Component suppliers confirm the trend, noting that global shipments of micro-controller-based smart compressors climbed to 48 million units last year, underscoring the pace of retrofitting. Download Sample Pages: Outside established economies, the household refrigerators and freezers market is also shaped by voluntary labels pioneered in India, Brazil, and Saudi Arabia that reward models consuming under 300 kilowatt-hours annually, spurring cross-border technology transfer. Whirlpool's Pune R&D center, for instance, adapted vacuum-insulated panels once reserved for Japanese apartments to meet India's Star-5 criteria, trimming cabinet thickness by nearly an inch without shrinking net capacity. Similar material-science gains are emerging in Latin America, where Electrolux is testing aerogel door gaskets sourced from Chilean start-ups. Because energy cost is the single most visible lifetime expense, retailers report that search-filter usage for 'energy saver' tags grew fivefold on leading e-commerce portals in 2024, confirming that efficiency narratives now directly affect conversion rates. Key Findings in Household Refrigerators and Freezers Market Market Forecast (2033) US$ 147.45 billion CAGR 4.20% Largest Region (2024) Asia Pacific (36%) By Door Type Double Door (65%) By Structure Freestanding (55%) Top Drivers Rising demand for smart refrigerators with automated defrost features Increasing consumer preference for energy-efficient appliances to reduce costs Urbanization and growing middle-class incomes in emerging economies Top Trends Adoption of refrigerators with customizable storage and modular designs Growth in demand for larger freezers due to bulk food storage Expansion of smart refrigerators with AI and IoT integration Top Challenges High production costs for advanced refrigerators with smart technologies Supply chain disruptions impacting raw material availability and manufacturing Regulatory pressures for eco-friendly refrigerants and energy compliance Consumer Financing Innovations Expand Ownership Among Lower Income Households Globally The household refrigerators and freezers market is unlocking latent demand among lower-income consumers through inventive financing vehicles that spread risk across data-driven micro-installment models. In 2024 Indonesia's Akulaku teamed with Sharp to bundle top-mount units for as little as US$ 3 weekly, using smartphone metadata to calibrate credit lines and issuing approvals in under two minutes. Latin American fintech Kueski Pay integrated with Whirlpool's online store, letting Mexican shoppers split US$ 650 French-door purchases over 24 fortnights; internal analytics show default rates below micro-credit norms, partly because the appliance is viewed as a productive asset that reduces food spoilage. These results illustrate how algorithmic underwriting widens refrigeration access in hotter climates. From a distribution standpoint, the household refrigerators and freezers market is blending financing with modular design tweaks to minimise upfront cash outlays. Midea offers refrigerators whose freezer compartment can be purchased later as a slide-in upgrade, effectively spreading expenditure over two fiscal periods. In Kenya, Sun King embeds pay-go controllers directly into DC-compressor circuits, disabling units only after a 12-hour grace period to preserve vaccines or groceries—maintaining goodwill while ensuring repayment discipline. Pakistan's Kamyab Pakistan Program has already logged 46,000 refrigerator beneficiaries under its subsidized Islamic-financing scheme. As big-data risk scoring matures, stakeholders expect ownership gaps to narrow sharply, boosting food security and grid-load balancing across emerging economies. Premiumization Driven By Urban Middle Class Demands Smart Cooling Solutions The household refrigerators and freezers market increasingly reflects a premiumization curve as urban middle-class consumers from Bangkok to Barcelona prioritize aesthetics, digital connectivity, and flexible storage over pure capacity. In 2023, global side-by-side and multi-door unit shipments reached 62 million, according to GfK, up from 55 million two years earlier, confirming a steady migration toward large-format platforms with automatic ice, crushed-ice, and hot-water dispensers. Samsung's Family Hub 7.0 panel now supports 6,000 recipe videos and Amazon Fresh cart synchronization, turning the fridge into an e-commerce gateway, while LG's MoodUP color-changing LEDs—unveiled at IFA 2023—equip retailers with an upsell story centered on kitchen personalization rather than raw cooling specs. Importantly, the household refrigerators and freezers market exhibits premium skews even in price-sensitive economies once credit access improves. Flipkart's no-cost EMI program triggered a fourfold jump in French-door sales during its Big Billion Days 2024 campaign, while Mexican chain Liverpool notes that add-on warranty attachment now reaches nine in ten units when bundled with smart-home speakers. Chinese OEMs are leveraging such data by launching mid-range sub-brands—Haier's Casarte and Midea's COLMO—that deliver app-enabled freshness diagnostics yet trim stainless-steel cladding to hit aspirational price points. These offerings show how premiumization today pivots less on luxury materials and more on embedded service ecosystems, insulating demand even as broader inflation pressures discretionary spending. Cold Chain Gaps Accelerate Chest Freezer Adoption In Developing Regions The household refrigerators and freezers market faces a unique dynamic in developing regions, where irregular power supply and incomplete distribution networks keep demand for standalone chest freezers stubbornly high. Nigeria imported close to 1.4 million deep-freezer units in 2023, customs records show, nearly matching its top-mount refrigerator inflows. Across rural Indonesia, World Bank data reveal monthly outage durations of 12 hours; consumers respond by purchasing 350-liter freezers capable of maintaining minus-eighteen-degree chambers for 36 hours without grid power. Multilateral agencies, including UNDP, increasingly procure solar-direct chest freezers from Sure Chill and B Medical Systems for smallholder vaccine storage, further broadening the installed base in off-grid villages. Consequently, the household refrigerators and freezers market proves that 'good-enough cooling' can outpace sophisticated IoT models when infrastructure realities intervene. Brands such as Hisense and Changhong tailor tropicalized compressors rated for ambient temperatures above forty-five degrees Celsius and reinforce lid gaskets to withstand Sahel dust storms. Financing solutions also adapt: East Africa's M-KOPA sells pay-as-you-go chest freezers bundled with 150-watt solar panels, and repayment data show default rates lower than those attached to smartphones, underscoring refrigerators' perceived productivity value. As national cold-chain investments advance—Kenya commissioned 130 new last-mile milk chillers in 2024—analysts expect gradual migration toward frost-free uprights, but timing will hinge on rural electrification milestones rather than headline macro growth. Omni-Channel Sales Strategies Blend DTC Platforms And Traditional Dealerships Seamlessly The household refrigerators and freezers market has shifted decisively toward omni-channel engagement, recognizing that consumers research online yet often finalize purchases in-store to inspect finish quality and hinge feel. US buying group BrandSource reports that 68,000 refrigerator leads originating from Google Local Inventory Ads in 2023 converted to showroom traffic within 72 hours, demonstrating the power of real-time stock visibility. Chinese giants are doubling down on direct-to-consumer: Haier's Smart Home app now supports live video consultations with installers, while delivered over 900,000 large-capacity units above 350 liters in 2023 using stair-climbing robots, cutting average delivery time in tier-one cities to under three hours. For smaller appliance dealers, the household refrigerators and freezers market presents both challenge and opportunity as social-commerce platforms reshape purchase paths. TikTok Shop's #KitchenUpgrade hashtag exceeded 2.3 billion views by April 2024, prompting GE Appliances to film how-to content tied to affiliate links. Conversely, Best Buy leverages its coast-to-coast network to provide same-day haul-away of legacy units, a service digital-only sellers struggle to match. As buy-online-pick-up-in-store penetration deepens, retailers able to synchronize cloud inventory, last-mile logistics, and after-sales service within a single mobile interface will widen competitive moats, especially in metro areas where delivery windows—not headline prices—now influence final cart decisions. Component Supply Constraints Encourage Regionalized Manufacturing And Localization Strategies Worldwide The household refrigerators and freezers market continues to navigate component bottlenecks—especially in semiconductors, copper tubing, and HFO refrigerants—that surfaced during the pandemic and persist in 2024 amid geopolitical fragmentation. Although automotive chip allocations have eased, high-inrush micro-controllers remain scarce, prompting Whirlpool to dual-source from Renesas in Japan and Microchip in Arizona. Residential construction booms within the Gulf Cooperation Council lifted demand for compressor alloys, pushing LME copper prices to an average of US$ 9,250 per metric ton in Q1 2024. To hedge exposure, Electrolux opened a 15,000-square-foot coil plant in Juarez, Mexico capable of stamping 3.5 million condensers annually, trimming cross-border trucking miles. In response, the household refrigerators and freezers market is seeing localization stretch beyond final assembly to compressor casting, PCB population, and foam chemical blending. Haier's Egyptian factory now sources roughly two-thirds of its sheet metal from local mills, while Hisense's South-African facility extrudes door liners in-house, shaving six weeks off supply cycles previously dependent on Ningbo shipping lanes. Brazil's Embraco is even licensing its full inverter-compressor range to India's Tata Power, signaling a shift from captive to collaborative supply chains. Analysts believe such regional diversification lowers currency risk and speeds compliance with local-content rules emerging across ASEAN and MERCOSUR, ultimately protecting downstream pricing despite raw-material volatility. Get a Customized Version: Cooling Technologies Advance With Hydrocarbon And Solid-State Refrigerants Adoption Trend The household refrigerators and freezers market now leads refrigerant innovation as mandates under the Kigali Amendment and US AIM Act tighten global-warming-potential thresholds. Hydrocarbon R-600a has become standard for charges under 1.5 kilograms; Gree alone shipped 29 million R-600a refrigerators in 2023, according to ChinaIOL. Europe is fast-tracking R-290 conversions even for side-by-side formats, prompting Danfoss to release A3-rated variable-speed compressors with spark arrestors. Beyond hydrocarbons, University of Maryland researchers recently demonstrated a solid-state barocaloric prototype delivering temperature lifts of 25 degrees Celsius under moderate pressure, hinting at a future without gaseous refrigerants. These advances create new differentiation vectors in the household refrigerators and freezers market, where marketing once revolved around door count but now highlights climate-impact scores. Liebherr's BluRoX, showcased at Chillventa 2024, swaps polyurethane foam for vacuum-housed perlite, adding eight liters of net volume on a 300-liter cabinet while lowering energy draw. GE Appliances is field-testing magnetocaloric wine coolers at luxury US resorts, recording vibration reductions that sommeliers say preserve cork integrity. Component ecosystems are mobilizing: Infineon's latest power modules target high-frequency inductor drivers used in magnetocaloric stages, suggesting supply chains are preparing for a post-compressor paradigm. As governments roll out rebate multipliers for ultra-low-GWP cooling, early adopters stand to capture environmentally conscious segments and lift brand equity. Global Household Refrigerators and Freezers Market Major Players: AB Electrolux Dacor Inc. Dover Corporation Godrej Industries Haier Group Corporation Kenmore LG Electronics Panasonic Corporation Philips Electronics Robert Bosch GmbH Samsung Electronics The Whirlpool Corporation Other Prominent Players Key Market Segmentation: By Door Type Double Door French Door Top Mounted Side by Side Single Door By Structure Built-in Freestanding By Distribution Channel Supermarkets/Hypermarkets Specialty Stores E-commerce Others By Region North America Europe Asia Pacific Middle East Africa South America Request Additional Details Before Purchase: About Astute Analytica Astute Analytica is a global market research and advisory firm providing data-driven insights across industries such as technology, healthcare, chemicals, semiconductors, FMCG, and more. We publish multiple reports daily, equipping businesses with the intelligence they need to navigate market trends, emerging opportunities, competitive landscapes, and technological advancements. With a team of experienced business analysts, economists, and industry experts, we deliver accurate, in-depth, and actionable research tailored to meet the strategic needs of our clients. At Astute Analytica, our clients come first, and we are committed to delivering cost-effective, high-value research solutions that drive success in an evolving marketplace. Contact Us:Astute AnalyticaPhone: +1-888 429 6757 (US Toll Free); +91-0120- 4483891 (Rest of the World)For Sales Enquiries: sales@ Follow us on: LinkedIn | Twitter | YouTube CONTACT: Contact Us: Astute Analytica Phone: +1-888 429 6757 (US Toll Free); +91-0120- 4483891 (Rest of the World) For Sales Enquiries: sales@ Website: in to access your portfolio

Biofuels Market Size to Exceed USD 326.42 Bn by 2034 Growing Need for Clean Energy is Driving Biofuels Adoption
Biofuels Market Size to Exceed USD 326.42 Bn by 2034 Growing Need for Clean Energy is Driving Biofuels Adoption

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Biofuels Market Size to Exceed USD 326.42 Bn by 2034 Growing Need for Clean Energy is Driving Biofuels Adoption

The global biofuels market size is predicted to increase from USD 110.9 billion in 2025 and is anticipated to be worth around USD 326.42 billion by 2034, expanding at a CAGR of 11.4% from 2025 to 2034. A study published by Statifacts a sister firm of Precedence Research. Ottawa, July 02, 2025 (GLOBE NEWSWIRE) -- According to Statifacts, the global biofuels market size was evaluated at USD 110.9 billion in 2024 and is estimated to attain USD 326.42 billion by 2034, growing at a CAGR of 11.4% during the forecast period from 2025 to 2034. Government initiatives for favorable regulatory measures and research endeavors, growing dependence on greenhouse gas emissions, and rising popularity as an eco-friendly fuel for road transportation are driving the growth of the market. This Report is Readily Available for Immediate Delivery, Visit Here to Explore the Report Sample and In-depth Databook Now@ Biofuels Market Overview The biofuels market refers to the production, distribution, and application of biofuels, which are liquid fuels produced from renewable biological sources, including plants and algae. Biofuels offer a solution to one of the challenges of wind, solar, and other alternative energy sources. Biofuels are fuels derived directly or indirectly from biomass. Biofuel benefits include supporting agriculture, rural development, reducing greenhouse gases, low pollution, economic stimulation, efficiency, renewable energy, low emissions, energy security, and reducing foreign oil dependence. The biofuels market growth is driven by government initiatives for suitable regulatory measures & research endeavors, growing dependence on reducing greenhouse gas emissions, rising demand for eco-friendly fuel for road transportation, and technological advancements. There is no emission of hazardous gases like sulfur dioxide (SO) and carbon monoxide (CO). By using biofuels instead of fossil fuels, there is only the emission of non-toxic materials, which reduces the risk of cancer and breathing problems in human beings. Biofuels Market Highlights North America dominated the global market with the largest market share in 2024. Asia Pacific is estimated to expand the fastest CAGR between 2025 and 2034. By fuel type, the bioethanol segment accounted for a considerable share of 72.1% in 2024. By feedstock, the vegetable oil segment registered its dominance over the global market share of 27.7% in 2024. Major Trends in the Biofuels Market What Is the Market Trend for Biofuels Market? Government initiative for suitable regulatory measures: The government policy on biofuels encourages the setting up of a supply chain mechanism for biodiesel production from short gestation crops, used cooking oil, and non-edible oilseeds. The roles and responsibilities of all the concerned departments or ministers concerning biofuels have been captured in the policy document to synergise efforts. India aims to achieve 20% ethanol blending with petrol by 2025-26, largely achieved through 1G ethanol from sugar cane and food grains. Global governments are offering a variety of incentives and enacting regulations to promote biofuel adoption. Technological advancements: Technological advancements in the biofuel industry, electro-fuels, which is a spark-ignited revolution in green hydrogen, synthetic biology designing the future molecules of green energy, waste-to-energy transforming trash into transportable fuel, and algae to oils, a green option, reshaping energy policies. Along with satisfying basic energy requirements, they reduce greenhouse gas emissions, provide energy security, and support regional development. The latest advancements in biofuels include advancements in enzyme technology, fermentation improvement, and the creation of integrated biorefineries capable of producing many streams of biofuel and bioproducts. Technological advancements promote the production and processing of biofuels. Ready to Dive Deeper? Visit Here to Buy Databook & In-depth Report Now@ Is Biofuel a Growing Industry? Yes, the biofuel industry is a growing one due to increasing research and development undertakings by both research institutions and biotechnology companies alike, along with high demand for cleaner fuels, pushed by the global switch to more sustainable and renewable energy forms. Regulatory support: Regulatory support for biofuels adoption, renewable fuel standards (RFS) create a stable and predictable market for biofuel manufacturers, the actuality furnished with the aid of government mandates fosters greater funding in biofuel technologies and infrastructure, and by using biofuels, the RFS allows less harmful emissions, contributing to international climate dreams. Government Policies Driving Biofuel Growth | Advance Biofuel Rising demand: Rising demand for biofuels is contributing to the growth of the biofuels market. Biofuels are green fuels in that they do not contribute to the carbon dioxide (CO2) burden. Biofuel is biodegradable and non-toxic. Unlike renewable diesel, petroleum diesel is derived from a non-renewable resource that will not run out. Growing dependence on reducing greenhouse gas emissions: Due to compatibility with the natural carbon cycle, bio-fuels offer the most beneficial alternative for reducing greenhouse gases from the transportation sector. The benefits of reducing greenhouse gas emissions' impacts on the world include a cut in consumption, regulatory compliance, enhanced stakeholder relations, enhanced external relations, cost savings, slowed climate change, economic growth, and air quality. Replacing fossil fuels with biofuels has the potential to reduce some undesirable environmental impacts of fossil fuel production and use, including conventional & greenhouse gas (GHG) pollutant emissions, exhaustible resource depletion, and dependence on unstable foreign suppliers. Role of Artificial Intelligence (AI) in the Biofuels Market Artificial intelligence (AI) role in biofuels provides an emerging and significant convergence in the relationship between advanced technology and energy produced from renewable sources. Many aspects of biofuel production are transformed by AI's data analytics, modelling & prediction abilities, and machine learning, from maximizing biomass utilization and increasing fuel production to improving methods of production and providing the preservation of the environment. AI in biofuels is used for improving biofuel production, such as adjusting irrigation and fertilizer usage to increase yield, conversion process, such as temperature adjusting, and improving pressure levels to improve the efficiency of biofuels. An AI-driven system can improve every stage, helping farmers to grow better feedstocks, enhancing production methods, ensuring fuel quality, and even reducing environmental impacts through smart assessments. Revolutionizing Renewable Energy: AI-Based Solutions for Sustainable Biofuel | IEEE Conference Publication | IEEE Xplore What are the Significant Achievements of the Leading Industrial Firms? According to a report published in September 2024, Petroleum Minister Hardeep S Puri Highlighted India's Bioenergy Progress at India Bio-Energy and Tech Expo 2024. Ethanol blending percentage surges from 1.53% in 2014 to 15% in 2024. E100 fuel launched at over 400 retail outlets nationwide. Puri urges the transport minister, Gadkari, to promote the production of E-100-compatible vehicles. Press Release: Press Information Bureau In May 2025, a landmark achievement in its efforts to deliver clean, locally sourced biofuels in Africa was announced by Jord, the Swedish renewable energy company. The Municipal Council of Sakar, located in Senegal's Sedhiou region, has allocated 300 hectares of land to Jord Africa. This allocation is part of a larger 1000-hectare plan that signals a strong commitment from both the company and local authorities to transform underutilized land into a hub for clean energy production. Jord launches Senegal biofuel project with 300 hectare land allocation - GreentechLead How Does IoT Act as an Opportunity for the Biofuels Market? The Internet of Things (IoT) in the energy sector presents a significant opportunity in the biofuels market, enhancing the operational efficiency, reliability, and sustainability of energy systems. It also helps integrate renewable energy sources, ensure better supply-demand response, and use energy more efficiently. For renewable energy sources, production levels fluctuate based on weather patterns and environmental conditions. IoT devices help to mitigate this variability by offering real-time monitoring and control. IoT technology improves the efficiency of smart grids by collecting real-time data on energy usage and grid performance. This information enables utilities to balance supply and demand effectively, integrate renewable energy solutions, and allow dynamic pricing models. The main purpose of IoT is to connect a multitude of devices and objects to the internet. This connectivity allows these devices to collect, share, and analyze information in real time. This IoT is a critical part of the technological development that is paving the way for a sustainable future. By integrating with renewable energy, environmental compliance, smart cities, waste management, agriculture, and energy management, IoT is having a deep impact on the health of our planet. Limitations and Challenges in the Biofuels Market What are the Potential Concerns Related to the Biofuels Market? Engine compatibility issues: The problems with biofuel engines include biodiesel may contain some 'unconverted' vegetable oil (incomplete processing), traces of chemicals from the making of the biodiesel can remain in the biodiesel. The engine either refuses to start in cold weather or runs only for a few seconds after starting. Biofuels are considered environmentally friendly; their increased water content and oxygen can cause corrosion and damage to fuel system components. Deposits and clogging because of biodiesel have been widely reported, but are generally traceable to biodiesel that is either of low quality or has become oxidized. Using Biodiesel Fuel in Your Engine High production costs: The cost of biofuel production is influenced by many factors, like feedstock selection, labor and land costs, the oil market, and agricultural subsidies. Technological advancements like CELF and advanced enzymatic hydrolysis drive efficiency and cost-effectiveness. The costs of biofuels mainly depend on labor and land costs, feedstock, oil market, and agricultural subsidies. Biofuels are more expensive than petrol. With the current price hikes in many of the feedstocks used for biofuels like cereals, vegetable oils used cooking oil, and animal fats, the price difference to fossil fuels is becoming ever larger. How Did North America Dominate the Biofuels Market in 2025? North America dominated the global biofuels market in 2025. Growing initiatives for suitable regulatory measures & research endeavors, growing dependence on reducing greenhouse gas emissions, and increasing popularity as an eco-friendly fuel for road transportation are driving the growth of the market in the North American region. How Do Biofuels Act as a Key to the Future of Renewable Energy in the United States? The United States holds the fourth-largest global refining capacity and ranks as the seventh-largest exporter of refined petroleum products. The United States is the leading biofuel producer in the World. According to a report published in July 2024 by IEA Bioenergy on biofuels production and development in the United States, the U.S. biofuel production capacity rose to 23.8 billion gallons per year (BGPY) in 2023, a growth of over 1.7 billion gallons compared to 2022. Ethanol production has reached 17.8 BGPY since 2023, while biodiesel production capacity stands at 2.1 BGPY, and renewable diesel capacity is now 3.9 BGPY. Biofuels production and development in the United States – Bioenergy What To Expect from Asia Pacific's Biofuel Market? Asia Pacific is anticipated to grow at the fastest rate in the market during the forecast period. Trend towards contactless interactions, the healthcare sector's expansion, growing adoption of cloud technology, and increasing demand for automation in appointment management are contributing to the biofuels market in the Asia Pacific region. How Do Biofuels Act as a Key to the Biofuels Market in India? The main source of biofuel is ethanol, which is primarily produced from sugarcane. Overall, ethanol from sugarcane remains the main source of biofuel used in India. In March 2025, according to the Minister of Petroleum and Natural Gas, India has emerged as the world's third-largest biofuel producer. India has achieved 19.6% ethanol blending in petrol as of January and is on track to reach 20%, five years ahead of its original 2030 target. Biofuels Market Scope Report Attribute Key Statistics Market Size in 2025 USD 141 Billion Market Size by 2034 USD 257.6 Billion Growth Rate from 2025 to 2034 CAGR of 6.9% Largest Market North America Fastest Growing Market Asia Pacific Base Year 2024 Forecast Period 2025 to 2034 Segments Covered By Fuel Type, By Feedstock, and By Region Regions Covered North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa Biofuels Market Segmentation Fuel Type Insights Biofuels Market Size by Fuel Type 2024 to 2034 (USD Million) Segment 2024 2025 2034 Biodiesel 37,031.4 39,802.5 79,377.0 Ethanol 95,103.4 1,01,201.1 1,78,224.2 What Made Bioethanol the Dominant Segment in the Biofuels Market in 2024? The bioethanol segment underwent notable growth in the market during 2024. Bioethanol is a fuel made from plant material like sugarcane or corn. It is produced by fermenting the sugars in the plants with yeast to produce ethanol and carbon dioxide. Bioethanol can be used in many ways, including producing ethanol-based fuel spray to clean industrial equipment and fuel in vehicles modified to run on it. Benefits of bioethanol include reducing air pollution, reducing dependence on crude oil, helping to reduce greenhouse gas emissions, mitigating global warming, and more. Bioethanol | Definition, Production Process, Uses, & Benefits The biodiesel fuel type segment is expected to grow at the fastest rate in the market during the forecast period of 2025 to 2034. Using biodiesel fuel as a vehicle fuel improves public health and the environment, as it provides safety benefits and contributes to a resilient transport system. Biodiesel in its pure, unblended form causes far less damage than petroleum diesel if released or spilled to the environment. Feedstock Insights Biofuels Market Size by Feedstock 2024 to 2034 (USD Million) Segments 2024 2025 2034 Coarse Grains 35,999.2 38,125.4 65,589.2 Non-agri Feedstock 11,729.8 12,703.4 25,817.6 Biomass 8,834.2 9,555.0 19,247.6 Vegetable oil 36,565.5 38,889.8 69,228.6 Sugar crop 22,300.6 23,729.9 42,407.4 Jatropha 3,688.4 4,248.2 12,133.9 Others 13,017.2 13,751.9 23,176.9 How the Vegetable Oil Segment Dominated the Biofuels Market in 2024? The vegetable oil segment enjoyed a prominent position in the market during 2024. Vegetable oils are used as a substitute for fossil fuels. Vegetable oils are the basis of biodiesel, which can be used like conventional diesel. Biodiesel is produced from vegetable oil by transesterification, a process that converts fats and oils into biodiesel and glycerin. Recycled used vegetable oil is used to produce renewable fuels, which are clean and therefore help minimize pollution. Carbon dioxide emissions are reduced when substituting traditional fuels with renewable fuels. The jatropha segment is projected to experience the highest growth rate in the market between 2025 and 2034. Benefits of jatropha as a biofuel include its resilience to harsh environmental conditions, adaptability to marginal lands, and ability to produce high yields of oil-rich seeds, making it a valuable resource for addressing the global energy crisis. The oil extracted from jatropha seeds can be converted into biodiesel, a renewable fuel alternative to fossil fuels. Browse More Research Reports: The global biogas market size accounted for USD 43,055 million in 2024 and is expected to exceed around USD 94,688 million by 2034, growing at a CAGR of 8.2% from 2024 to 2034. The global bioethanol market size was estimated at USD 86.5 billion in 2024 and is projected to be worth around USD 124.16 billion by 2034, growing at a CAGR of 3.68% from 2025 to 2034. The global fuel storage tank market size accounted for USD 15,400 million in 2024 and is expected to exceed around USD 24,610 million by 2034, growing at a CAGR of 4.8% from 2024 to 2034. The global gasoline fuel additives market size was USD 214.15 million in 2023, calculated at USD 226.14 million in 2024 and is expected to reach around USD 389.96 million by 2034, expanding at a CAGR of 5.6% from 2024 to 2034. The global octane improver fuel additives market size was USD 98 million in 2023, calculated at USD 103.49 million in 2024 and is expected to reach around USD 178.46 million by 2034, expanding at a CAGR of 5.6% from 2024 to 2034. Ready to Dive Deeper? Visit Here to Buy Databook & In-depth Report Now@ Competitive Landscape in the Biofuels Market BTG International Ltd.: This company is an international specialist healthcare company that is developing and commercializing products targeting critical care, cancer, and other disorders. Renewable Energy Group, Inc.: This company is a leader in the biofuels industry, providing lower-carbon fuel solutions to fleets. Abengoa Bioenergy S.A.: This company is a global leader in the development of new industrial biotechnologies and debuts an advanced biorefinery for cellulosic ethanol in Southwest Kansas. Cargill: Cargill is committed to providing food, ingredients, agricultural solutions, and industrial products to nourish the world in a safe, responsible, and sustainable way. DowDuPont, Inc.: It is a leader in Agriculture and Specialty Products, combining the complementary portfolios, resources, and capabilities of heritage Dow and DuPont. Wilmar International Ltd: Wilmar International Ltd's business activities include oil palm cultivation, edible oils refining, oilseeds crushing, consumer-packaged edible oils processing and merchandising, specialty fats, oleochemicals, biodiesel manufacturing, gains processing and merchandising, and sugar milling and refining. POET, LLC: This is a US biofuel company that specializes in the creation of bioethanol. Archer Daniels Midland Company: They are a global leader in human and animal nutrition and the world's premier agricultural organization and processing company. VERBIO Vereinigte BioEnergie AG: They produce biofuels and chemical products from rapeseed oil, rye, wheat, triticale, maize, and straw. My Eco Energy: They specialize in creating renewable fuel solutions and green energy innovations. China Clean Energy Inc.: This is a biodiesel and specialty chemical producer operating in the People's Republic of China and selling products both domestically and worldwide. What Are the Latest Advancements in Biofuels? In May 2025, the forthcoming release of BioxiGuard, Japan's first antioxidant specially developed for marine biodiesel fuel ('biofuel'), was announced by an NYK Group Company specializing in chemical R&D as well as the manufacture and sale of chemical products, Nippon Yuka Kogyo Co., Ltd. NYK Group Company Launches Japan's First Antioxidant for Marine Biodiesel Fuel | NYK Line In April 2025, 'Scheme for Implementation of Biofuel Projects in Madhya Pradesh', under the Madhya Pradesh Renewable Energy Policy, 2025, was officially launched by the Madhya Pradesh Government in a significant move towards a sustainable future. Madhya Pradesh Launches Biofuel Scheme to Boost Sustainability - Asia Pacific | Energetica India Magazine Segments Covered in the Report By Fuel Type Biodiesel Bioethanol By Feedstock Coarse Grain Non-agri Feedstock Biomass Vegetable Oil Sugar Crop Jatropha Others By Geography North America U.S. Canada Europe Germany France United Kingdom Rest of Europe Asia Pacific China Japan India Southeast Asia Rest of Asia Pacific Latin America Brazil Rest of Latin America Middle East & Africa (MEA) GCC North Africa South Africa Rest of Middle East & Africa You can place an order or ask any questions, please feel free to contact us at sales@ Statifacts offers subscription services for data and analytics insights. This page provides options to explore and purchase a subscription tailored to your needs, granting access to valuable statistical resources and tools. Access here - Contact US Ballindamm 22, 20095 Hamburg, Germany Web: Europe: +44 7383 092 044 About US Statifacts is a leading provider of comprehensive market research and analytics services, offering over 1,000,000 market and custoer data sets across various industries. Their platform enables businesses to make informed strategic decisions by providing full access to statistics, downloadable in formats such as XLS, PDF, and PNG. For Latest Update Follow Us: Our Trusted Data Partners: Precedence Research | Towards Healthcare | Towards Packaging | Towards Automotive | Towards Food and Beverages | Towards Chemical and Materials | Towards Dental | Towards EV Solutions | Nova One AdvisorError in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

I-Mab Presents Positive Givastomig Phase 1b Dose Escalation Data in Combination with Immunochemotherapy in Patients with 1L Gastric Cancers at ESMO GI 2025
I-Mab Presents Positive Givastomig Phase 1b Dose Escalation Data in Combination with Immunochemotherapy in Patients with 1L Gastric Cancers at ESMO GI 2025

Associated Press

timean hour ago

  • Associated Press

I-Mab Presents Positive Givastomig Phase 1b Dose Escalation Data in Combination with Immunochemotherapy in Patients with 1L Gastric Cancers at ESMO GI 2025

Data show confirmed ORR of 83% (10/12) at doses selected for ongoing expansion study Median follow-up of 9.0 months as of the updated data cutoff Responses observed in patients with low PD-L1 and/or CLDN18.2 expression Company to host investor event on Tuesday, July 8th ROCKVILLE, Md., July 02, 2025 (GLOBE NEWSWIRE) -- I-Mab (NASDAQ: IMAB) (the Company), a U.S.-based, global biotech company, focused on the development of precision immuno-oncology agents for the treatment of cancer, today announced the presentation of positive Phase 1b combination data for givastomig, in combination with nivolumab and mFOLFOX6, at the European Society for Medical Oncology Gastrointestinal Cancers Congress 2025 (ESMO GI 2025) in Barcelona (abstract #388MO) . Givastomig is a bispecific antibody targeting Claudin 18.2 and 4-1BB. I-Mab plans to host a virtual investor event on Tuesday, July 8th (register here ) to review these data. The Phase 1b data (NCT04900818) show a confirmed objective response rate (ORR) of 71% across all doses (12/17), and 83% (10/12) at doses selected for the ongoing dose expansion study (8 mg/kg and 12 mg/kg). Responses occurred in tumors with low levels of PD-L1 expression and/or Claudin 18.2 (CLDN18.2) expression, with favorable overall tolerability. There were no Grade 3 or greater events for nausea and vomiting, and only one Grade 3 TRAE for increased liver enzymes. The data are based on the results of the dose escalation part of a Phase 1b study evaluating the givastomig combination as first line therapy (1L) in patients with Claudin 18.2-positive gastric cancers (≥1+ IHC staining intensity in ≥1% of tumor cells). The primary endpoint is safety. The study enrolled only patients in the U.S. 'The positive Phase 1b combination data presented at ESMO GI bolster our confidence in givastomig's potential to be a best-in-class Claudin 18.2 directed therapy. Givastomig has been well tolerated when combined with immuno-oncology and chemotherapy, has shown a high objective response rate, with rapid onset and durable responses that have deepened over time, supported by consistent pharmacokinetic data and soluble 4-1BB induction,' said Phillip Dennis, MD, PhD, Chief Medical Officer of I-Mab. 'In addition, we are optimistic about the results from the 8 mg/kg and 12 mg/kg doses. These doses showed an ORR of 83%, with consistent responses across PD-L1 and Claudin 18.2 expression levels, and a favorable overall safety profile. These data further our conviction in the ongoing Phase 1b dose expansion study. We believe givastomig has broad potential in a number of gastric cancer settings and look forward to continued advancement of the program.' 'I am encouraged by the response rates, as well as the deepening of responses over time, demonstrated by the givastomig combination regimen in the Phase 1b dose escalation study that we presented today at ESMO GI. Despite approved therapies, targeted treatment options for gastric cancers continue to be limited. While the data are early, givastomig combination therapy demonstrates a high response rate across Claudin 18.2 and PD-L1 expression levels,' said Samuel J Klempner, MD, Associate Professor of Medicine at Massachusetts General Hospital. 'In addition, I have been pleased to observe that givastomig has a favorable overall tolerability profile with a low level of gastrointestinal side effects -- especially important for patients with gastric cancer. I look forward to participating in the ongoing givastomig clinical development program, and hope we may be able to expand the population of patients who may benefit from Claudin 18.2 directed agents.' Virtual Investor Event: Register ( here ) for the Post-ESMO GI 2025 Investor Event to be held on Tuesday, July 8th at 2:00 PM EDT. A replay of the webinar will be accessible on the Events page of the I-Mab website for 90 days. Fireside Chat Event with Lucid Capital Markets to Recap the Presentation: Tune in ( here ) for a fireside chat sponsored by Christopher Liu, PharmD, Managing Director at Lucid Capital Markets that will be accessible today at 2:00pm EDT on the Events page of the I-Mab website. A replay of the fireside chat will be available for 90 days. ESMO GI Presentation Details: A full copy of the ESMO GI presentation is available on the Publications and Presentations page of the I-Mab website here. Givastomig Phase 1b Dose Escalation Data Summary in 1L Gastric Cancers Patient Characteristics: Efficacy Results: Durability: Safety: About Givastomig Givastomig (TJ033721 / ABL111) is a bispecific antibody targeting Claudin 18.2 (CLDN18.2)-positive tumor cells. It conditionally activates T cells through the 4-1BB signaling pathway in the tumor microenvironment where CLDN18.2 is expressed. Givastomig is being developed for first line (1L) metastatic gastric cancers, with further potential in other solid tumors. In Phase 1 trials, givastomig has shown promising anti-tumor activity attributable to a potential synergistic effect of proximal interaction between CLDN18.2 on tumor cells and 4-1BB on T cells in the tumor microenvironment, while minimizing toxicities commonly seen with other 4-1BB agents. An ongoing Phase 1b study is evaluating givastomig for the treatment of gastric cancer in the 1L setting in combination with standard of care, nivolumab (an anti-PD-1 checkpoint inhibitor) plus chemotherapy, in dose escalation and dose expansion cohorts. Dose escalation is complete, and enrollment in the first dose expansion cohort (n=20) finished ahead of schedule. Enrollment continues to progress ahead of schedule in the second dose expansion cohort (n=20). The study builds on positive Phase 1 monotherapy data. Givastomig is being jointly developed through a global partnership with ABL Bio, in which I-Mab is the lead party and shares worldwide rights, excluding Greater China and South Korea, equally with ABL Bio. About I-Mab I-Mab (NASDAQ: IMAB) is a U.S.-based, global biotech company, focused on the development of precision immuno-oncology agents for the treatment of cancer. The Company's differentiated pipeline is led by givastomig, a potential best-in-class, bispecific antibody (Claudin 18.2 x 4-1BB) designed to treat Claudin 18.2-positive gastric cancers. Givastomig conditionally activates T cells via the 4-1BB signaling pathway in the tumor microenvironment where Claudin 18.2 is expressed. Givastomig is being developed for first-line metastatic gastric cancers, with additional potential in other solid tumors. In Phase 1 trials, givastomig was observed to maintain strong tumor-binding and anti-tumor activity, attributable to a potential synergistic effect of proximal interaction with Claudin 18.2 and 4-1BB, while minimizing toxicities commonly seen with other 4-1BB agents. For more information, please visit and follow us on LinkedIn and X. I-Mab Forward Looking Statements This announcement contains forward-looking statements. These statements are made under the 'safe harbor' provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as 'will', 'expects', 'believes', 'designed to', 'anticipates', 'future', 'intends', 'plans', 'potential', 'estimates', 'confident', and similar terms or the negative thereof. I-Mab may also make written or oral forward-looking statements in its periodic reports to the U.S. Securities and Exchange Commission (the SEC), in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or employees to third parties. Statements that are not historical facts, including statements about I-Mab's beliefs and expectations, are forward-looking statements. Forward-looking statements in this press release include, without limitation, statements regarding: the Company's pipeline and clinical development of I-Mab's drug candidates, including givastomig; the projected advancement of the Company's portfolio and anticipated milestones and related timing; the Company's expectations regarding the impact of data from ongoing and future clinical trials; the timing and progress of studies and trials (including with respect to patient enrollment); the potential benefits of givastomig; and the availability of data and information from ongoing studies and trials. Forward-looking statements involve inherent risks and uncertainties that may cause actual results to differ materially from those contained in these forward-looking statements, including but not limited to the following: I-Mab's ability to demonstrate the safety and efficacy of its drug candidates; the clinical results for its drug candidates, which may or may not support further development or New Drug Application/Biologics License Application (NDA/BLA) approval; the content and timing of decisions made by the relevant regulatory authorities regarding regulatory approval of I-Mab's drug candidates; I-Mab's ability to achieve commercial success for its drug candidates, if approved; I-Mab's ability to obtain and maintain protection of intellectual property for its technology and drugs; I-Mab's reliance on third parties to conduct drug development, manufacturing and other services; and I-Mab's limited operating history and I-Mab's ability to obtain additional funding for operations and to complete the development and commercialization of its drug candidates, as well as those risks more fully discussed in the 'Risk Factors' section in I-Mab's annual report on Form 20-F filed with the SEC on April 3, 2025, as well as the discussions of potential risks, uncertainties, and other important factors in I-Mab's subsequent filings with the SEC. All forward-looking statements are based on information currently available to I-Mab. I-Mab undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise, except as may be required by law. I-Mab Investor & Media Contacts PJ Kelleher LifeSci Advisors +1-617-430-7579 [email protected] [email protected]

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