Single injection sees seven-year-old regain almost all hearing
A clinical trial, detailed in Nature Medicine, involved injecting a healthy OTOF gene into the inner ear of 10 participants with OTOF gene mutations.
All participants experienced significant hearing improvement, with a seven-year-old girl regaining almost full hearing within weeks of treatment.
The therapy led to rapid hearing recovery, often within a month, and sustained improvement over six months, with children aged five to eight responding best.
Researchers confirmed the treatment was safe and well-tolerated, and are now exploring similar therapies for other genetic causes of deafness.
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