Fat jabs slash risk of silent killer which affects thousands of Brits a year by HALF, incredible study finds
Users had a lower danger than those who had slimming surgery — even if they did not lose as much weight, a study found.
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Fat jabs could become a super weapon in the fight against cancer
Credit: Getty
It suggests injections like Ozempic, Wegovy and Mounjaro have anti-cancer effects on top of reducing the risk by burning fat.
Cancer experts now want to test tens of thousands of people in a crucial clinical trial..
They believe the effects on inflammation, hormones and chemicals in the blood might offer added protection on top of the benefits of weight loss.
Dr Matthew Harris, of the Manchester Cancer Research Centre, said: 'Injectable weight loss medications give a genuinely promising possible option for cancer prevention in the future.'
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Experts believe their effects on inflammation, hormones and chemicals in the blood might add extra protection on top of the benefits of weight loss.
A study compared 3,200 patients who lost weight with GLP-1 injections with 3,200 who had surgery.
Follow-up tests showed the cancer rate in surgical patients compared with jab patients.
Study author Dr Yael Wolff Sagy, of Clalit Health Services in Israel, said: 'When we took into account the differences in weight reduction, we found the jabs were 41 per cent more effective at preventing cancer.
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'This indicates there is an additional mechanism beyond simple weight loss. We believe this effect may come from reducing inflammation.
'This is potentially very exciting news for patients at high risk of obesity-related cancer and possibly other cancers.'
Professor Mark Lawler, from Queen's University Belfast, was not part of the study but commented: 'We already know that bariatric surgery cuts obesity-related cancer risk by about a third and these data suggest that GLP-1s may cut that risk by nearly 50 per cent.
'This work could herald a whole new era of preventative cancer medicine.'
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Dr Harris and dozens of international researchers told the European Congress on Obesity that a trial pitting the jabs against cancer should be a priority.
It could involve comparing disease rates among tens of thousands of patients with and without the drugs over a number of years.
Obesity is the second most common cause of cancer in the UK, behind smoking, and around a third of Brits are severely overweight.
Dr Harris added: 'There is going to be a massive increase in obesity related cancers so if we're able to prevent them it could be a really significant public health intervention.'
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Experts hope the trial could be under way within three to five years.
Everything you need to know about fat jabs
Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases.
Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK.
Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market.
Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year.
How do they work?
The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight.
They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists.
They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients' sugar levels are too high.
Can I get them?
NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics.
Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure.
GPs generally do not prescribe the drugs for weight loss.
Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk.
Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health.
Are there any risks?
Yes – side effects are common but most are relatively mild.
Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea.
Dr Sarah Jarvis, GP and clinical consultant at patient.info, said: 'One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.'
Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia.
Evidence has so far been inconclusive about whether the injections are damaging to patients' mental health.
Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines.
Julia Hartley-Brewer slams government plan for NHS to offer free 'fat jabs' to tackle obesity crisis
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The Irish Sun
6 hours ago
- The Irish Sun
Can't get fat jabs on the NHS? The 6 ‘Nozempic' foods that mimic the effects of weight-loss injections
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But certain foods can put the brakes on hunger like this too… THE 'NOZEMPIC' DIET 'EVERYBODY creates GLP-1 after they eat, along with a whole swathe of other hormones that tell us we're full and don't necessarily need to carry on eating,' says Emily Lenoir, a registered associate nutritionist and behaviour change coach at Voy. 'There are a few foods that might increase the feeling of fullness, and that often is in relation to a slight peak in GLP-1.' So, pop these in your basket when you next do a big shop… 1. MEAT FEAST 7 Protein takes longer digest and seems to increase GLP-1 levels which will help support that feeling of fullness for longer Credit: Getty CHICKEN, turkey, salmon, eggs… 'Protein takes a little bit longer to digest; it stays in our stomach for longer,' says Lenoir. 'There also seems to be a slight increase in GLP-1 after eating protein.' She adds: 'If a quarter of your meals is coming from protein, which is often what we recommend, then you're likely to have that meal stay in your stomach for a bit longer, and help support that feeling of fullness.' Research from 2020 found that egg whites are particularly handy for GLP-1 release, so get boiling. 2. THE F-WORD 7 Eating fibres in your meal will help slow digestion and make sure you feel fuller Credit: Getty 'That comes from a variety of fruits and vegetables,' says Lenoir. 'If you're getting a whole range of fibres - fermentable fibres (loved by good gut bacteria), and soluble fibres (which slow digestion) - in your meal, that will help slow digestion and make sure you're feeling fuller." Insoluble fibre includes wholegrains like brown rice and wholegrain cereals, as well as leafy greens, nuts and seeds. Soluble fibre, the best type for keeping you full, includes oats, lentils, beans, apples, pears and root vegetables. It turns into a gel-like substance in the gut. Like fat jabs - but by different mechanism - this slows the rate at which food exits, keeping you fuller for longer. Berries are incredibly fibre-rich, as are apples, broccoli, peas, beans and Brussels sprouts. Some studies have found you can reduce glucose spikes, often caused by carbs, by eating your veg first, but Lenoir says not to worry about that too much. 'If you're eating carbohydrates alongside lots of different foods, you're likely to manage that quite well anyway,' she says. And eating things separately isn't always realistic. 'If you're making Bolognese, you're not going to split that up into your veggies, beef and then pasta,' says Lenoir. 3. OATS SO SIMPLE 7 Overnight oats and homemade granola ticks all the boxes to help you feel fuller Credit: Getty GO big on homemade granola and porridge for breakfast to curb hunger pangs through the day - oats are a soluble A 2024 study in the Journal of Nutrition, led by University of Arizona, showed that beta-glucan, found in insoluble fibres like oats, barley and mushrooms, was the only type of fibre that helped mice lose weight by facilitating the release of GLP-1. Lenoir says: 'Oats are high in fibre and have some proteins. 'They tick all the boxes in that respect and definitely help people feel fuller. 'It's important to also pair your meals so you're having a bit of everything. WHO IS ELIGIBLE FOR WEIGHT LOSS JABS ON THE NHS? NHS eligibility for weight loss injections has expanded but still lags behind the number who could potentially benefit from taking them. Wegovy, medical name semaglutide, is only available for weight loss through specialist weight management clinics. Patients are typically expected to have tried other weight loss methods before getting a prescription. They may be eligible if their body mass index (BMI) is higher than 30, or higher than 27 if they have a weight-related health condition such as high blood pressure. Mounjaro, known as tirzepatide, is also available from GP practices but currently only to patients with a BMI of 40 or higher (or 37.5 if from a minority ethnic background) plus four weight-related health conditions. The medicines are currently being rationed to the patients most in need. NHS watchdog NICE estimates that more than three million Brits will ultimately be eligible. The GLP-1 injections are prescribed separately by GPs for people with type 2 diabetes, and patients should discuss this with their doctor. 'Oats are the majority carbohydrates, so you want to pair that with some yogurt, berries, nuts and seeds on top, to give you that full variety. 'That can help you feel satisfied for a prolonged period, and stop that big peak and trough that can come from a higher carb meal.' 4. GO NUTS 7 Having a handful of almonds or pistachios as a snack might increase your GLP-1 levels too Credit: Getty NUTS can divide a room - some people feel saintly snacking on them, but others are wary of eating too many for fear of getting fat. However, a review from 2016 revealed almonds, pistachios, and peanuts might actually increase GLP-1 levels thanks to being packed with protein, fibre and healthy fats. Lenoir says: 'They're shown to overall be quite beneficial if you're adding a handful here and there, but obviously, if you were eating a huge amount, that might have an impact on your energy levels across a day.' Too many could also impact your waistline, so keep portion sizes under control. 5. 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Extra.ie
7 hours ago
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Top comedian Alison Spittle speaks out on fat jabs and online abuse
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