Latest news with #Ozempic
Perth Now
39 minutes ago
- Health
- Perth Now
Five things you should know before having a weight loss jab
GLP-1 medications are a major breakthrough for people to shed pounds and manage conditions such as Type 2 diabetes. However, doctors say there's a perception that weight-loss drugs such as semaglutide (brand names Ozempic and Wegovy) and tirzepatide (Mounjaro) are all you need to live a healthier life. Diet and exercise still matter, said JoAnn Manson, chief of the division of preventive medicine at Brigham and Women's Hospital in Boston. 'They remain crucial,' Dr Manson said. 'If you're not paying attention to protein intake, hydration and having regular physical activity — especially resistance training — you can end up with poor nutritional status and substantial muscle loss.' GLP-1 drugs mimic a hormone the body produces to regulate hunger and blood sugar. The injections cut cravings for food, slow digestion and keep people feeling full for longer periods of time. However, since the drugs affect the stomach's functions, they also can cause gastrointestinal side effects such as nausea and vomiting. Some people stop taking the drugs because of these gut symptoms. Still, Dr Manson said, with some 'relatively straightforward' changes in behaviour, people can minimise these problems and continue using the drug. Dr Manson is a co-author of two articles — one for clinicians and another for patients — that were recently published in JAMA Internal Medicine. Here are five things Dr Manson and her co-authors want people on these medications to know. These medications can help someone lose around 15 to 21 per cent of their body weight. But a significant portion of that weight - up to one-fourth - can be lean body mass and muscle, Dr Manson said. This protein can come from chicken, fish, beans, chickpeas or tofu, Dr Manson said. Aim for 1 to 1.5 grams of protein each day per kilogram (2.2 pounds) of body weight. If you don't have an appetite or are eating smaller meals, you may want to try drinking a protein shake throughout the day as a supplement. Dr Manson and her co-authors suggest filling a plate this way: half fruits and vegetables, one-quarter protein, and the rest whole grains. You can strengthen your muscles with bands, weights and body-weight exercises to counteract the potential loss in lean body mass, Dr Manson said. Aim for 60 to 90 minutes of resistance training and 150 minutes of aerobic exercise, such as brisk walking, per week. Water can help with the dehydration and constipation associated with the weight-loss drugs, said Dr Manson, who recommended 8 to 12 glasses per day. You also can eat water-rich foods such as cucumbers and watermelon to stay hydrated. And the researchers recommend that people on GLP-1 drugs limit their intake of alcohol, caffeine, and sugary or artificially sweetened beverages. This may help reduce your risk of heartburn. Add fibre to help with constipation, and avoid high-fat foods - or fried foods - because they can worsen feelings of nausea. Andres J Acosta, an associate professor of medicine and a consultant in gastroenterology and hepatology at the Mayo Clinic, who has also consulted for Novo Nordisk and Eli Lilly, and has co-founded two weight-loss-associated companies, Phenomix Sciences and Gila Therapeutics, said he often finds that patients have a 'preconceived notion' that they just need to take the medication and they'll lose weight. But the clinical trials for these weight-loss drugs included 'comprehensive programs' with lifestyle interventions for a calorie-reduced diet and exercise program. 'This perception — just take the shot and don't do anything else - is wrong. It's not going to drive real, long-term behavioural changes,' said Professor Acosta, who is a co-author of The Mayo Clinic Diet: Weight-Loss Medications Edition. 'Patients aren't going to see the outcomes that we're seeing in the trials.' The GLP-1 medications are one tool in a broader weight-management program, Professor Acosta said. He tells people they still need to have a healthy diet, with 'a good amount of protein' and enough water to stay well hydrated. 'I like to set the expectations from the get-go,' Professor Acosta said. 'And I also tell them that not everyone is going to lose weight.' Some people will gain back weight when they stop taking these medications, said Elizabeth Mietlicki-Baase, an associate professor of exercise and nutrition sciences at the University of Buffalo. Researchers are interested in 'finding strategies to prevent weight regain after discontinuation,' she said. 'But we don't have a great handle on that just yet.' (c) 2025 , The Washington Post
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Business Standard
3 hours ago
- Business
- Business Standard
Dr Reddy's to launch obesity drug in 87 nations starting next year: CEO
Dr Reddy's Laboratories plans to launch a cheaper copycat version of Novo Nordisk's blockbuster weight-loss drug Wegovy in 87 countries next year, the Indian drugmaker's CEO, Erez Israeli, said on Wednesday. The plan for launch of generic semaglutide, active ingredient of Novo's Wegovy and Ozempic, comes as drugmakers race to grab a share of the global obesity drug market which is expected to generate around $150 billion in sales by the early 2030s. The company initially plans to launch the generic version in Canada, India, Brazil, Turkey and other emerging markets, subject to patent expiry, Israeli said at a press conference. "U.S. and Europe will open later," he added. Dr Reddy's has filed relevant regulatory applications in all the countries it is planning to launch the generic version in, Israeli said. Semaglutide will go off patent in India in March next year. (Only the headline and picture of this report may have been reworked by the Business Standard staff; the rest of the content is auto-generated from a syndicated feed.)
Yahoo
4 hours ago
- Business
- Yahoo
Trump Uses Unhinged MAGA Math in Bonkers Drugs Brag
President Donald Trump has promised to reduce American drug prices by mathematically impossible figures of up to '1400 percent.' Speaking during a White House event attended by Republican members of Congress and his Cabinet, Trump said he would tackle the long-running issue of high medication costs in the U.S. But Trump did not set any achievable targets for that aim, instead outlining a range of percentages which would yield negative prices, meaning drug companies would have to pay people to take their medications. 'We will have reduced drug prices by 1,000 percent by 1100, 1200, 1300, 1400, 700, 600,' Trump said. 'Not 30 or 40 or 50 percent, but numbers the likes of which you've never even dreamed of before.' Trump added that his numbers were previously 'not even thought to be achievable,'—mainly because they aren't—but he believes he can somehow pull it off because 'I've used a certain talent that I have and convinced the drug companies that you have no choice.' Trump's threat involves warning European countries that they will no longer be able to sell cars in the U.S. unless their pharmaceutical companies lower their drug prices. 'You're no longer allowed to have Mercedes, BMW, Volkswagen or any of the other many cars and they will say, 'Oh, I love the idea of lower drug prices for America.'' Trump's bragging about how much he claims he will lower drug costs in the U.S. has been widely mocked after a clip of his remarks went viral on social media. 'Hard to imagine this guy was found liable of fraud for making up numbers,' the liberal media company MeidasTouch posted on X. Justin Wolfers, economist and professor at the University of Michigan, added: 'Thank goodness this guy isn't negotiating the percentages we pay in tariffs.' In May, Trump announced his plans to 'almost immediately' cut drug prices by the actually theoretically possible figures of between 30 percent and 80 percent. Trump said the move would be one of the 'most consequential' executive orders in the country's history. During his Tuesday speech, Trump repeated a story about how one of his friends who takes the 'fat drug' Ozempic complained to him about how he paid $88 for it in London, whereas it would cost him $1,300 in New York. 'I explained to him that that's the way it's been for many, many years,' Trump said. The White House did not immediately respond to a request for comment from The Daily Beast.
Jordan News
5 hours ago
- Health
- Jordan News
Study Warns of Weight Regain After Stopping Popular Weight Loss Medications - Jordan News
Weight loss medications are increasingly being used as an effective treatment for obesity, significantly helping adults reduce excess weight. Among the most well-known of these drugs are Ozempic and Wegovy, which both contain the active ingredient semaglutide, along with other approved medications aimed at controlling weight and improving overall health. Numerous studies and clinical trials are being conducted to evaluate the efficacy of these drugs, their effects on the body, and the challenges related to their use and discontinuation. اضافة اعلان In this context, a new study has found that patients taking weight-loss medications like Ozempic and Wegovy may regain the weight they lost within a few weeks of stopping the medication. The research team, including scientists from Peking University People's Hospital in China, analyzed data from 11 clinical trials involving around 2,500 participants. They found that most patients gradually regained weight after ending the treatment. The review, published in BMC Medicine, revealed that weight regain typically begins around eight weeks after stopping the medication and may continue for up to 20 weeks before stabilizing. Most of the trials focused on semaglutide, one of six approved medications for treating obesity in adults. Originally developed to treat type 2 diabetes, semaglutide has gained widespread popularity as an effective weight loss drug. The findings showed that the substantial weight loss achieved through these medications is often followed by a rapid regain once the drugs are discontinued. Researchers also observed that factors such as the type of medication and adherence to lifestyle changes—including diet and exercise—significantly impacted the rate of weight regain. For instance, patients who took tirzepatide for 36 weeks regained nearly half of the lost weight after switching to a placebo. The researchers stressed the need for long-term studies to better understand the factors influencing weight change after discontinuing weight loss medications, with the goal of improving obesity treatment strategies and preventing weight regain. Source: The Independent
Daily Mirror
5 hours ago
- Entertainment
- Daily Mirror
Sharon Osbourne said Ozzy hated her Ozempic use as she reveals why she did it
Sharon Osbourne revealed her beloved late husband, Ozzy Osbourne, was worried about her about using Ozempic, which she took to help her lose weight Sharon Osbourne admitted her late husband, Ozzy Osbourne, was concerned about his much-loved wife after she started using Ozempic. The mum-of-three, 72, tried the drug, which is designed to treat diabetes - but is now used for weight loss - in 2023 to help her lose a few pounds. However, after injecting Ozempic, which manages glucose levels, Mrs O, who stopped taking the medication after weighing less than 100 lbs., admitted she had lost too much weight, which left doting husband Ozzy concerned. Revealing she was tired of her weight "going up and down", she told Ben Shephard and Kate Garraway on ITV 's Good Morning Britain: 'I was just fed up of going back and forth with my weight, constantly like this. And I just thought, I've tried everything – everything I've tried. And so, I thought well, might as well try it (Ozempic) and I did.' However, admitting that her husband was not a fan of the drug, she confessed: 'He doesn't like it. And he's scared. He thinks that something's going to happen to me. (He thinks) 'This is it. There's nothing's perfect. If you've got skinny, then something else is gonna happen.'' Speaking on whether she was happy with her weight loss, she concluded: 'I could do with putting on a few pounds, but at this point, the way my body is, it's not listening. It's staying where it is.' Sharon, who is now grieving the tragic loss of her husband Ozzy, after he passed away at the age of 76, mere weeks after his final gig in his home city of Birmingham, has spoken openly about her health concerns over the years. The fiercely protective mum was diagnosed with bowel cancer in the summer of 2002, the same year that The Osbournes premiered on MTV. Sharon, who found fame as Ozzy's manager, did everything she could to protect her children from the heartbreaking realities of the disease, which had spread to her lymph nodes. In a recent interview with Metal Hammer, the X Factor star was asked why she continued working during her illness. Sharon replied: "Because I didn't want my kids and my husband to know how sick I was. When you say 'cancer', everybody always thinks 'death'. And you've got to remember it was 23 years ago." The Celebrity Big Brother star continued: "At that point, cancer wasn't the same as it is now. So everybody always thought it was a death sentence and I didn't want my kids to have fear constantly surrounding them. I didn't want it." Sharon, then 49, didn't shy away from discussing her cancer while filming, with the show including everything from her chemotherapy treatment to her decision to turn to Cher's wig maker after her hair fell out. However, although the family put on a brave united front, Ozzy later opened up about his fears for Sharon's life in an interview with Classic Rock magazine. He revealed: "I thought she was going to die. I never knew anybody that had survived cancer. As far as I was concerned, patient plus cancer equals death. But my wife is a very strong woman."
