Hyperpigmented Skin? Why Tranexamic Acid Is The Ingredient To Know
Now, tranexamic acid (also denoted by TXA) can be found over the counter and almost everywhere you look. As a beauty editor with skin prone to hyperpigmentation, tranexamic acid serums have been a saving grace. To find out how tranexamic acid works so well, I asked experts for a full breakdown. Ahead, you'll find everything you need to know about the ingredient, from the ideal concentration to all the best tranexamic acid products to use.
Debbie Thomas is a skin and laser expert, VIP facialist and the founder of Clinic.
is a skin and laser expert, VIP facialist and the founder of Clinic. Dr Tatyana Lapa-Wright is an aesthetic doctor and the owner of Hardwick Clinic.
What is tranexamic acid?
'Tranexamic acid is a synthetic derivative of the amino acid lysine,' Dr. Lapa-Wright informs Vogue. It's not an acid in the conventional sense—it does not have exfoliating properties. But it does have brightening benefits on the skin. According to Thomas, tranexamic acid is used topically for treating pigmentation and inflammatory redness. 'It effectively reduces excess melanin production without bleaching or stripping the skin and is ideal for melasma, post-inflammatory pigmentation, and redness-prone skin.'
How does tranexamic acid work on skin?
Oral tranexamic acid is a controlled medicine, typically prescribed to help with menstrual symptoms or nosebleeds, though some dermatologists may prescribe the pills for melasma patients. Whether oral or topical, TXA works by inhibiting tyrosinase (an enzyme that triggers pigment production) to reduce the appearance of dark patches. Studies have shown that tranexamic acid can also reduce inflammation, which makes it helpful in the prevention and reduction of post-inflammatory hyperpigmentation (PIH). Both of our experts add that TXA strengthens the skin barrier, evens skin tone, and can soothe redness when used as part of a dedicated routine.
How to use tranexamic acid for hyperpigmentation:
'Apply tranexamic acid once daily (evening preferred), after cleansing and before moisturizer,' Thomas instructs. 'Avoid layering with strong acids or retinoids initially—use it on its own for two to three weeks before introducing other actives.' Per Dr. Lapa-Wright, beginners should start low and go slow, as TXA can be irritating on sensitive skin. And don't skip the sun protection, which Thomas says will protect your results: 'Use a broad spectrum SPF, and if it is tinted, even better.'
How long does it take for tranexamic acid to work?
Timelines given by our experts vary, but both agree that tranexamic acid offers 'gradual results, not overnight miracles.' On average, you can expect to notice visible improvements in 8 to 16 weeks with consistent use.
What to look for in an effective tranexamic acid formula
Optimal concentration : According to Thomas, effective tranexamic acid formulas will have TXA listed within the top half of the ingredients list, ideally at a 2 to 5% concentration. 'Higher isn't always better,' Dr. Lapa-Wright notes.
: According to Thomas, effective tranexamic acid formulas will have TXA listed within the top half of the ingredients list, ideally at a 2 to 5% concentration. 'Higher isn't always better,' Dr. Lapa-Wright notes. Additional ingredients: Both experts recommend looking for TXA paired with complementary actives such as niacinamide, azelaic acid, and liquorice root, which safely enhance its effects. 'Avoid irritants like alcohol and fragrances, especially for sensitive skin.'
Both experts recommend looking for TXA paired with complementary actives such as niacinamide, azelaic acid, and liquorice root, which safely enhance its effects. 'Avoid irritants like alcohol and fragrances, especially for sensitive skin.' Protective packaging: Per Thomas, look for airtight, opaque packaging that protects ingredient stability.
Now you know what to look for and how best to introduce tranexamic acid into your skincare routine, you can try using the ingredient to get closer to your clear skin goals.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


CNN
39 minutes ago
- CNN
Sliding vaccine rates hang over vote on CDC director nominee as US measles cases hit dangerous milestone
The US Centers for Disease Control and Prevention on Wednesday tallied the highest number of US measles cases since the disease was declared eliminated a quarter-century ago, just as a key Senate committee split the vote to advance President Donald Trump's nominee to lead the public health agency. There have been more measles cases in the US this year than any other since the disease was declared eliminated a quarter-century ago, according to CDC data, with at least 1,288 confirmed cases. Just halfway through the year, the case tally has already surpassed the previous record from 2019, when there were a total of 1,274 cases. And it's well above the average of about 180 measles cases that have been reported each year since the disease was declared eliminated in the US in 2000. CNN reported this new milestone on Saturday using data from the Johns Hopkins University Center for Outbreak Response Innovation, which updates its numbers more frequently than the CDC. HHS has not responded to CNN's request for comment about the measles milestone. Childhood vaccine coverage has been declining in the US, and the vast majority of measles cases this year – more than 90% – have been in people who were unvaccinated or whose vaccination status was unknown, according to the CDC. When the measles case count reached its previous record in 2019 – during the first Trump administration – both the CDC director and the secretary of the US Department of Health and Human Services at the time released statements emphasizing the safety and effectiveness of the measles-mumps-rubella (MMR) vaccine and encouraging Americans to get vaccinated. However, almost six months into Trump's second term, the CDC still does not have a director and HHS Secretary Robert F. Kennedy Jr. has a long and complicated history with measles vaccines. Concerns about vaccine skepticism were front and center Wednesday as members of the Senate Health, Education, Labor and Pensions Committee voted to advance President Donald Trump's nominee to lead the CDC, Dr. Susan Monarez, for a vote by the full Senate. Committee members voted 12-11 to move Monarez's nomination. All of the committee's Republicans backed the longtime immunologist and government scientist, who spoke in her confirmation hearing about restoring trust in the CDC and defended Kennedy's decision to replace the members of a federal panel of vaccine advisers. The vote puts Monarez one step closer to taking the helm at the public health agency, and she will now progress to a full Senate vote. HELP Chairman Sen. Bill Cassidy, a Louisiana Republican and a doctor, voted to advance Monarez's nomination but nodded to falling vaccine coverage and the ongoing measles outbreak. 'Dr. Monarez will work to modernize our data health systems, to improve public health coordination and response while protecting American sensitive health information,' Cassidy said. 'This is especially crucial as the nation combats reemerging public health threats like measles, which has taken three lives in the United States this year.' He continued: 'One that's not included but is tragic: A Canadian woman who was pregnant got exposed to measles and lost her child. [The ongoing outbreak has] hospitalized many more due to misinformation regarding the measles vaccine.' Cassidy publicly pressed Kennedy last month to delay a meeting of the health agency's new vaccine advisers — several of whom have expressed skepticism and safety concerns about long-approved immunizations — amid concerns about their biases. During Wednesday's meeting, Sen. Patty Murray, a Washington Democrat, called on the committee to hold a hearing about the ongoing measles outbreak and Kennedy's shakeup of vaccine oversight. 'I am concerned because this committee, it feels like, has all but abandoned its serious oversight of this crisis,' she said. 'We haven't had a hearing on the record-breaking number of measles outbreaks or a hearing on how the CDC vaccine panel is now stacked with people who are actually not vetted, and all the previous board members, every single one of them, was removed with no credible explanation.' There needs to be congressional oversight of these actions, Murray said after casting a vote against Monarez. 'I really do hope that Dr. Monarez will defy my expectations. I hope she will stand up for science and put public health first. But again, I hope I have hoped that for others, and here we are today,' she said. Some health experts have emphasized the importance of vaccination rates and their trepidation about precedents being set under Kennedy's leadership of HHS. 'It is no surprise that the most widespread measles outbreak affecting the United States in a generation has occurred under Secretary Kennedy's watch,' Dr. Richard Besser, president and CEO of the Robert Wood Johnson Foundation and former acting director of the CDC, said in a statement Wednesday. 'His decades-long campaign to discredit vaccines at every turn, which has continued unabated during his time as health secretary, directly contributes to the alarming decline in routine childhood vaccination rates in our country that is resulting in more frequent outbreaks of vaccine-preventable diseases,' he said. 'In addition, the dramatic funding cuts to public health will mean that small outbreaks will grow and spread.' Three people have died of measles in the US this year – two children in Texas and one adult in New Mexico, all of whom were unvaccinated – matching the total number of US measles deaths from the previous two and a half decades. 'I worry that even more children will be forced to pay with their lives or health because of Secretary Kennedy's malfeasance,' Besser said. 'As a pediatrician, I strongly encourage all parents to talk to their healthcare providers, listen to their local public health officials, and learn the facts about measles vaccines, which are incredibly effective and safe.' The MMR vaccine is highly effective. One dose offers 93% protection against measles, and two doses are 97% effective, according to the CDC. 'Vaccines work—full stop. They are one of the most powerful tools we have to protect patients, families and entire communities. We can prevent diseases through vaccines, but too many diseases that we once had under control are starting to reappear because people are choosing to delay or skip immunization,' Dr. Jennifer Brull, president of the American Academy of Family Physicians, said in a statement. 'There's a lot of confusion around vaccinations, but patients don't have to navigate this alone. Family physicians, pediatricians, pharmacists and other public health workers can help patients wade through all the information and cut through the noise,' she said. 'The bottom line is vaccines are safe, effective and save lives. It's critical that we continue to protect not just individual families, but the health of our entire nation.'


CNN
40 minutes ago
- CNN
Biden's physician refuses to answer questions from Republicans in House probe of former president's mental fitness
Joe Biden's White House physician on Wednesday declined to answer questions during a closed-door deposition with the House Oversight Committee, invoking his Fifth Amendment right as the Republican-led panel pushes forward in its probe of the former president's mental fitness and decline. While Dr. Kevin O'Connor appeared on Capitol Hill Wednesday, his attorneys said he 'respectfully declined to answer any questions' from the panel, which had refused to limit the scope of the interview – imperiling, they said, his physician-patient privilege. 'Revealing confidential patient information would violate the most fundamental ethical duty of a physician, could result in revocation of Dr. O'Connor's medical license, and would subject Dr. O'Connor to potential civil liability. Dr. O'Connor will not violate his oath of confidentiality to any of his patients, including President Biden,' O'Connor's attorneys said in a statement on his behalf. The investigation is the latest front in the GOP push to expose alleged cover-ups by Biden and his inner circle that had fallen dormant in the last Congress. Republicans say the interviews are critical to supporting claims of the former president's cognitive decline in the final days of his administration. Democrats, meanwhile, have dismissed the probe in its entirety as a political stunt. The panel subpoenaed O'Connor in June after first seeking a voluntary interview, and has requested interviews with nearly a dozen former White House aides in recent months. But the interviews, which began as voluntary appearances, have grown increasingly contentious after President Donald Trump waived executive privilege for the physician and others. O'Connor's team on Wednesday argued the panel should pause its probe until the Department of Justice concludes its separate criminal investigation into his predecessor's actions and use of the autopen, which Trump had ordered in a memorandum. 'We believe that the Committee should hold its investigation in abeyance until any criminal investigation has concluded,' O'Connor's team said. A committee aide pushed back on the notion that O'Connor pleaded the Fifth Amendment because of doctor-patient privilege, arguing the physician did not answer any questions beyond his name. Invoking the Fifth Amendment is typically done to avoid answering specific questions. Though it can be perceived by the public as a way of avoiding accountability, the US Supreme Court has long regarded the right against self-incrimination as a venerable part of the Constitution and, in legal proceedings, tried to ensure that a witness' silence not be viewed as evidence of guilt. Following O'Connor's departure, House Oversight Chair James Comer accused the doctor of wanting to 'conceal the truth.' 'The American people demand transparency, but Dr. O'Connor would rather conceal the truth. Dr. O'Connor took the Fifth when asked if he was told to lie about President Biden's health and whether he was fit to be President of the United States,' the Kentucky Republican said in a statement. The committee still has multiple interviews scheduled throughout the summer. Unable to invoke executive privilege to avoid answering questions, some witnesses have already sought to stave them off. Former Biden aide Anthony Bernal withdrew from a voluntary interview last month after the White House counsel's office made clear that privilege would be waived. Comer then subpoenaed Bernal for his testimony. At least one interview has already led to a dispute over testimony. Comer claimed that Neera Tanden, Biden's director of the Domestic Policy Council, told the committee during her voluntary closed-door interview last month that she had 'no visibility' into how the approval for Biden's autopen signatures worked – a point that Republicans have latched onto. A Democratic committee official, however, swiftly pushed back on that characterization, saying that Tanden 'repeatedly and explicitly confirmed that she received President Biden's written sign-off on every executive action she presented him with.' 'Any other characterization is a distortion of the testimony,' the official told CNN at the time. Interview transcripts from Tanden's appearance have not yet been released. The top Democrat on the House Oversight Committee, Rep. Robert Garcia of California, criticized the Republican effort, saying the GOP is more concerned with the former president's health than their constituents' access to health care. 'The only person's health that Republicans care about is Joe Biden's – even as 17 million Americans lose access to affordable health care thanks to their big budget betrayal,' Garcia said in a statement. One Biden ally accused Republicans of playing politics with the congressional inquiry. 'It's an attempt to smear and embarrass. And their hope is for just one tiny inconsistency between witnesses to appear so that Trump's DOJ can prosecute his political opponents and continue his campaign of revenge,' the person told CNN.


CNN
41 minutes ago
- CNN
Sliding vaccine rates hang over vote on CDC director nominee as US measles cases hit dangerous milestone
The US Centers for Disease Control and Prevention on Wednesday tallied the highest number of US measles cases since the disease was declared eliminated a quarter-century ago, just as a key Senate committee split the vote to advance President Donald Trump's nominee to lead the public health agency. There have been more measles cases in the US this year than any other since the disease was declared eliminated a quarter-century ago, according to CDC data, with at least 1,288 confirmed cases. Just halfway through the year, the case tally has already surpassed the previous record from 2019, when there were a total of 1,274 cases. And it's well above the average of about 180 measles cases that have been reported each year since the disease was declared eliminated in the US in 2000. CNN reported this new milestone on Saturday using data from the Johns Hopkins University Center for Outbreak Response Innovation, which updates its numbers more frequently than the CDC. HHS has not responded to CNN's request for comment about the measles milestone. Childhood vaccine coverage has been declining in the US, and the vast majority of measles cases this year – more than 90% – have been in people who were unvaccinated or whose vaccination status was unknown, according to the CDC. When the measles case count reached its previous record in 2019 – during the first Trump administration – both the CDC director and the secretary of the US Department of Health and Human Services at the time released statements emphasizing the safety and effectiveness of the measles-mumps-rubella (MMR) vaccine and encouraging Americans to get vaccinated. However, almost six months into Trump's second term, the CDC still does not have a director and HHS Secretary Robert F. Kennedy Jr. has a long and complicated history with measles vaccines. Concerns about vaccine skepticism were front and center Wednesday as members of the Senate Health, Education, Labor and Pensions Committee voted to advance President Donald Trump's nominee to lead the CDC, Dr. Susan Monarez, for a vote by the full Senate. Committee members voted 12-11 to move Monarez's nomination. All of the committee's Republicans backed the longtime immunologist and government scientist, who spoke in her confirmation hearing about restoring trust in the CDC and defended Kennedy's decision to replace the members of a federal panel of vaccine advisers. The vote puts Monarez one step closer to taking the helm at the public health agency, and she will now progress to a full Senate vote. HELP Chairman Sen. Bill Cassidy, a Louisiana Republican and a doctor, voted to advance Monarez's nomination but nodded to falling vaccine coverage and the ongoing measles outbreak. 'Dr. Monarez will work to modernize our data health systems, to improve public health coordination and response while protecting American sensitive health information,' Cassidy said. 'This is especially crucial as the nation combats reemerging public health threats like measles, which has taken three lives in the United States this year.' He continued: 'One that's not included but is tragic: A Canadian woman who was pregnant got exposed to measles and lost her child. [The ongoing outbreak has] hospitalized many more due to misinformation regarding the measles vaccine.' Cassidy publicly pressed Kennedy last month to delay a meeting of the health agency's new vaccine advisers — several of whom have expressed skepticism and safety concerns about long-approved immunizations — amid concerns about their biases. During Wednesday's meeting, Sen. Patty Murray, a Washington Democrat, called on the committee to hold a hearing about the ongoing measles outbreak and Kennedy's shakeup of vaccine oversight. 'I am concerned because this committee, it feels like, has all but abandoned its serious oversight of this crisis,' she said. 'We haven't had a hearing on the record-breaking number of measles outbreaks or a hearing on how the CDC vaccine panel is now stacked with people who are actually not vetted, and all the previous board members, every single one of them, was removed with no credible explanation.' There needs to be congressional oversight of these actions, Murray said after casting a vote against Monarez. 'I really do hope that Dr. Monarez will defy my expectations. I hope she will stand up for science and put public health first. But again, I hope I have hoped that for others, and here we are today,' she said. Some health experts have emphasized the importance of vaccination rates and their trepidation about precedents being set under Kennedy's leadership of HHS. 'It is no surprise that the most widespread measles outbreak affecting the United States in a generation has occurred under Secretary Kennedy's watch,' Dr. Richard Besser, president and CEO of the Robert Wood Johnson Foundation and former acting director of the CDC, said in a statement Wednesday. 'His decades-long campaign to discredit vaccines at every turn, which has continued unabated during his time as health secretary, directly contributes to the alarming decline in routine childhood vaccination rates in our country that is resulting in more frequent outbreaks of vaccine-preventable diseases,' he said. 'In addition, the dramatic funding cuts to public health will mean that small outbreaks will grow and spread.' Three people have died of measles in the US this year – two children in Texas and one adult in New Mexico, all of whom were unvaccinated – matching the total number of US measles deaths from the previous two and a half decades. 'I worry that even more children will be forced to pay with their lives or health because of Secretary Kennedy's malfeasance,' Besser said. 'As a pediatrician, I strongly encourage all parents to talk to their healthcare providers, listen to their local public health officials, and learn the facts about measles vaccines, which are incredibly effective and safe.' The MMR vaccine is highly effective. One dose offers 93% protection against measles, and two doses are 97% effective, according to the CDC. 'Vaccines work—full stop. They are one of the most powerful tools we have to protect patients, families and entire communities. We can prevent diseases through vaccines, but too many diseases that we once had under control are starting to reappear because people are choosing to delay or skip immunization,' Dr. Jennifer Brull, president of the American Academy of Family Physicians, said in a statement. 'There's a lot of confusion around vaccinations, but patients don't have to navigate this alone. Family physicians, pediatricians, pharmacists and other public health workers can help patients wade through all the information and cut through the noise,' she said. 'The bottom line is vaccines are safe, effective and save lives. It's critical that we continue to protect not just individual families, but the health of our entire nation.'